6173 results
Cited 3 times since 2022 (1 per year)
source: EuropePMC
Drug discovery today,
Volume 27, Issue 6, 4 1 2022, Pages 1716-1723
Advanced molecular imaging for the characterisation of complex medicines.
Yilmaz D, Sharp PS, Main MJ, Simpson PB
A growing number and diversity of complex medicines is in development and reaching the market, with many of these medicines utilising innovative delivery technology to achieve appropriate biodistribution and exposure. Accurate assessment of biodistribution, cell penetration, internalised form, cargo release and efficacy are essential for the development of these medicines. Advanced imaging technologies, deploying different labelling techniques that allow the assessment of both carrier and cargo,...
Abstract
Cited 7 times since 2022 (2.2 per year)
source: EuropePMC
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
Volume 30, Issue 3, 3 1 2022, Pages 364-371
Normalization of Time-Intensity Curves for Quantification of Foot Perfusion Using Near-Infrared Fluorescence Imaging With Indocyanine Green.
Van Den Hoven P, Tange F, Van Der Valk J, Nerup N, Putter H, Van Rijswijk C, Van Schaik J, Schepers A, Vahrmeijer A, Hamming J, Van Der Vorst J
Purpose: Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) is gaining popularity for the quantification of tissue perfusion, including foot perfusion in patients with lower extremity arterial disease (LEAD). However, the absolute fluorescence intensity is influenced by patient-and system-related factors limiting reliable and valid quantification. To enhance the quality of quantitative perfusion assessment using ICG NIR fluorescence imaging, normalization of the measured time...
Abstract
Cited 3 times since 2022 (1 per year)
source: EuropePMC
Seminars in nuclear medicine,
Volume 52, Issue 5, 2 1 2022, Pages 597-610
Nuclear medicine imaging methods of radiation-induced cardiotoxicity.
Polomski ES, Antoni ML, Jukema JW, Kroep JR, Dibbets-Schneider P, Sattler MGA, de Geus-Oei LF
Breast cancer survival is significantly improved over the past decades due to major improvements in anti-tumor therapies and the implementation of regular screening, which leads to early detection of breast cancer. Therefore, it is of utmost importance to prevent patients from long-term side effects, including radiotherapy-induced cardiotoxicity. Radiotherapy may contribute to damage of myocardial structures on the cellular level, which eventually could result in various types of cardiovascular...
Abstract
Cited 7 times since 2022 (2.2 per year)
source: EuropePMC
Vascular and endovascular surgery,
Volume 56, Issue 5, 2 1 2022, Pages 472-479
Doppler Ultrasonography Derived Maximal Systolic Acceleration: Value Determination With Artificially Induced Stenosis.
Brouwers JJWM, van Doorn LP, Pronk L, van Wissen RC, Putter H, Schepers A, Hamming JF
BackgroundIn diagnosing peripheral arterial disease (PAD), medial arterial calcification (MAC) hampers arterial compression and could lead to unreliable ankle brachial index (ABI), toe brachial index (TBI) and toe pressure (TP). Doppler ultrasonography (DUS) derived maximal systolic acceleration (ACCmax) might be more accurate to diagnose PAD. In an in vitro study, a strong correlation between ACCmax and the severity of stenotic disease was determined. The aim of this study was to investigate th...
Abstract
Cited 28 times since 2022 (8.9 per year)
source: EuropePMC
JACC. Cardiovascular interventions,
Volume 15, Issue 5, 1 1 2022, Pages 523-532
The PARTNER 3 Bicuspid Registry for Transcatheter Aortic Valve Replacement in Low-Surgical-Risk Patients.
Williams MR, Jilaihawi H, Makkar R, O'Neill WW, Guyton R, Malaisrie SC, Brown DL, Blanke P, Leipsic JA, Pibarot P, Hahn RT, Leon MB, Cohen DJ, Bax JJ, Kodali SK, Mack MJ, Lu M, Webb JG
Objectives: The study compared 1-year outcomes between transcatheter aortic valve replacement (TAVR) patients with bicuspid aortic valve (BAV) morphology and clinically similar patients having tricuspid aortic valve (TAV) morphology. Background: There are limited prospective data on TAVR using the SAPIEN 3 device in low-surgical-risk patients with severe, symptomatic aortic stenosis and bicuspid anatomy. Methods: Low-risk, severe aortic stenosis patients with BAV were candidates for the PARTNER...
Abstract
Cited 6 times since 2022 (1.9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 4, 1 1 2022, Pages 578-585
Prognostic implications of cardiac damage classification based on computed tomography in severe aortic stenosis.
Hirasawa K, vanRosendael PJ, Fortuni F, Singh GK, Kuneman JH, Vollema EM, Ajmone Marsan N, Knuuti J, Bax JJ, Delgado V
Aims: An echocardiographic staging system of severe aortic stenosis (AS) based on additional extra-valvular cardiac damage has been associated with prognosis after transcatheter aortic valve implantation (TAVI). Multidetector row computed tomography (MDCT) is key in the evaluation of AS patients undergoing TAVI and can potentially detect extra-valvular cardiac damage. This study aimed at evaluating the prognostic implications of an MDCT staging system of severe AS in patients undergoing TAVI. Me...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
European journal of cardiovascular nursing,
Volume 21, Issue 2, 1 1 2022, Pages 169-173
Implantable cardioverter-defibrillators and the older patient: the Dutch clinical practice.
Yilmaz D, Egorova AD, Schalij MJ, van Erven L
Background and objective: Balance between benefit and burden of implantable cardioverter-defibrillator (ICD) therapy is more debatable in older patients, compared to younger patients. Of around 6000 yearly implanted ICDs in the Netherlands, 1:4 is received by patients ≥75 years. We aimed to evaluate the current clinical practice in the Netherlands for ICD implants and generator replacements, with a special focus on the older ICD patients. Research design and methods: Cardiologists from all Dutch...
Abstract
Cited 5 times since 2022 (1.6 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 4, 1 1 2022, Pages 447-449
How to do lung ultrasound.
Stassen J, Bax JJ
Abstract
Cited 33 times since 2022 (10.5 per year)
source: EuropePMC
Diabetes care,
Volume 45, Issue 3, 1 1 2022, Pages 674-683
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.
DiCorpo D, LeClair J, Cole JB, Sarnowski C, Ahmadizar F, Bielak LF, Blokstra A, Bottinger EP, Chaker L, Chen YI, Chen Y, de Vries PS, Faquih T, Ghanbari M, Gudmundsdottir V, Guo X, Hasbani NR, Ibi D, Ikram MA, Kavousi M, Leonard HL, Leong A, Mercader JM, Morrison AC, Nadkarni GN, Nalls MA, Noordam R, Preuss M, Smith JA, Trompet S, Vissink P, Yao J, Zhao W, Boerwinkle E, Goodarzi MO, Gudnason V, Jukema JW, Kardia SLR, Loos RJF, Liu CT, Manning AK, Mook-Kanamori D, Pankow JS, Picavet HSJ, Sattar N, Simonsick EM, Verschuren WMM, Willems van Dijk K, Florez JC, Rotter JI, Meigs JB, Dupuis J, Udler MS
Objective: Type 2 diabetes (T2D) has heterogeneous patient clinical characteristics and outcomes. In previous work, we investigated the genetic basis of this heterogeneity by clustering 94 T2D genetic loci using their associations with 47 diabetes-related traits and identified five clusters, termed β-cell, proinsulin, obesity, lipodystrophy, and liver/lipid. The relationship between these clusters and individual-level metabolic disease outcomes has not been assessed. Research design and methods:...
Abstract
Cited 9 times since 2022 (2.9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 4, 1 1 2022, Pages 515-523
Orientation of the right superior pulmonary vein affects outcome after pulmonary vein isolation.
Szegedi N, Vecsey-Nagy M, Simon J, Szilveszter B, Herczeg S, Kolossváry M, Idelbi H, Osztheimer I, Klaudia Nagy V, Tahin T, Széplaki G, Delgado V, Bax JJ, Maurovich-Horvat P, Merkely B, Gellér L
Aims: Controversial results have been published regarding the influence of pulmonary vein (PV) anatomical variations on outcomes after pulmonary vein isolation (PVI). However, no data are available on the impact of PV orientation on the long-term success rates of point-by-point PVI. We sought to determine the impact of PV anatomy and orientation on atrial fibrillation (AF)-free survival in patients undergoing PVI using the radiofrequency point-by-point technique. Methods and results: We retrospe...
Abstract
Cited 8 times since 2022 (2.5 per year)
source: EuropePMC
American journal of epidemiology,
Volume 191, Issue 5, 1 1 2022, Pages 886-899
Evaluation of the Value of Waist Circumference and Metabolomics in the Estimation of Visceral Adipose Tissue.
Boone SC, van Smeden M, Rosendaal FR, le Cessie S, Groenwold RHH, Jukema JW, van Dijk KW, Lamb HJ, Greenland P, Neeland IJ, Allison MA, Criqui MH, Budoff MJ, Lind LL, Kullberg J, Ahlström H, Mook-Kanamori DO, de Mutsert R
Visceral adipose tissue (VAT) is a strong prognostic factor for cardiovascular disease and a potential target for cardiovascular risk stratification. Because VAT is difficult to measure in clinical practice, we estimated prediction models with predictors routinely measured in general practice and VAT as outcome using ridge regression in 2,501 middle-aged participants from the Netherlands Epidemiology of Obesity study, 2008-2012. Adding waist circumference and other anthropometric measurements on...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
The Journal of cardiovascular nursing,
Volume 37, Issue 2, 1 1 2022, Pages 192-196
Type D Personality Associated With Increased Risk for Mortality in Adults With Congenital Heart Disease.
Kauw D, Schoormans D, Sieswerda GT, Van Melle JP, Vliegen HW, Van Dijk APJ, Hulsbergen-Zwarts MS, Post MC, Ansink TJ, Mulder BJM, Bouma BJ, Schuuring MJ
Background: Type D personality has been previously shown to increase the risk for mortality in patients with acquired heart disease. Objective: We aimed to compare mortality in adult patients with congenital heart disease (CHD) with and without type D. Methods: Survival was assessed using prospective data from the Dutch national Congenital Corvitia registry for adults with CHD. Patients were randomly selected from the registry and characterized at inclusion in 2009 for the presence of type D usi...
Abstract
Cited 20 times since 2022 (6.4 per year)
source: EuropePMC
JAMA cardiology,
Volume 7, Issue 3, 1 1 2022, Pages 309-319
Association of Plaque Location and Vessel Geometry Determined by Coronary Computed Tomographic Angiography With Future Acute Coronary Syndrome-Causing Culprit Lesions.
Han D, Lin A, Kuronuma K, Tzolos E, Kwan AC, Klein E, Andreini D, Bax JJ, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, Hadamitzky M, Kim YJ, Leipsic JA, Maffei E, Marques H, Plank F, Pontone G, Villines TC, Al-Mallah MH, de Araújo Gonçalves P, Danad I, Gransar H, Lu Y, Lee JH, Lee SE, Baskaran L, Al'Aref SJ, Yoon YE, Van Rosendael A, Budoff MJ, Samady H, Stone PH, Virmani R, Achenbach S, Narula J, Chang HJ, Min JK, Lin FY, Shaw LJ, Slomka PJ, Dey D, Berman DS
Importance: Distinct plaque locations and vessel geometric features predispose to altered coronary flow hemodynamics. The association between these lesion-level characteristics assessed by coronary computed tomographic angiography (CCTA) and risk of future acute coronary syndrome (ACS) is unknown. Objective: To examine whether CCTA-derived adverse geometric characteristics (AGCs) of coronary lesions describing location and vessel geometry add to plaque morphology and burden for identifying culpr...
Abstract
Cited 5 times since 2022 (1.6 per year)
source: EuropePMC
The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland,
Volume 21, Issue 1, 28 4 2022, Pages 1-7
Exploring the surgical personality.
Sier VQ, Schmitz RF, Schepers A, van der Vorst JR
Surgery is a demanding field, requiring determination and emotional stability. This review explores the surgical personality, addressing international personality differences between surgical and non-surgical specialties. Across the globe, surgically-interested individuals (i.e., medical students, residents, surgeons) generally scored higher on conscientiousness, open mindedness, and extraversion, and lower on neuroticism compared to non-surgically-interested contemporaries. Extraversion was inv...
Abstract
The international journal of cardiovascular imaging,
Volume 38, Issue 5, 26 4 2022, Pages 927-929
Patterns of cardiac involvement characterized by strain echocardiography in amyloidosis.
Tjahjadi C, Fortuni F, Stassen J, Marsan NA, Delgado V, Bax JJ
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 30, Issue 6, 24 4 2022, Pages 338-339
Multiple culprit lesions in ST-segment elevation myocardial infarction with cardiogenic shock: a case of simultaneous thrombosis of two infarct-related arteries.
Caliskan R, Ince H, Arslan F
Abstract
Cited 8 times since 2022 (2.5 per year)
source: EuropePMC
JMIR cardio,
Volume 6, Issue 1, 22 4 2022, Pages e29473
A Preoperative Virtual Reality App for Patients Scheduled for Cardiac Catheterization: Pre-Post Questionnaire Study Examining Feasibility, Usability, and Acceptability.
Aardoom JJ, Hilt AD, Woudenberg T, Chavannes NH, Atsma DE
Background: Pre- and postoperative anxiety is a common phenomenon associated with negative postoperative outcomes. Symptoms of posttraumatic stress disorder, such as fear, nightmares, and sleep deprivation, are prevalent in approximately 30% to 50% of patients following discharge from intensive care units after cardiac surgery. Preliminary evidence suggests a promising role of virtual reality (VR) in preventing stress-related reactions using stress inoculation training. Such training enables cog...
Abstract
Frontiers in psychiatry,
Volume 13, 22 4 2022, Pages 774251
Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies.
Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C
Background: In non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the treatment/exposure group and control group. This may bias the study and consequently a meta-analysis (MA) estimate. These estimates may differ across statistical methods used to deal with this issue. Analysis of individual participant data (IPD) allows standardization of methods acr...
Abstract
The American journal of cardiology,
Volume 170, 21 3 2022, Pages 1-9
Prognostic Relevance of Right Ventricular Remodeling after ST-Segment Elevation Myocardial Infarction in Patients Treated With Primary Percutaneous Coronary Intervention.
Chimed S, van der Bijl P, Lustosa RP, Hirasawa K, Yedidya I, Fortuni F, van der Velde E, Montero-Cabezas JM, Marsan NA, Gersh BJ, Delgado V, Bax JJ
ST-segment elevation myocardial infarction (STEMI) often leads to changes in right ventricular (RV) function and size over time. The prognostic implications of RV remodeling after STEMI, however, are unknown. RV remodeling in patients who underwent STEMI with primary percutaneous coronary intervention (PCI) was defined by RV end-systolic area (RV ESA) change at 6 months after STEMI compared with baseline. The optimal threshold of RV ESA change (≥40%) to define RV remodeling was derived from spli...
Abstract
Cited 3 times since 2022 (0.9 per year)
source: EuropePMC
International journal of cardiology,
Volume 355, 18 3 2022, Pages 65-71
Prognostic implications of staging cardiac remodeling in patients undergoing cardiac resynchronization therapy.
Stassen J, Khidir M, Galloo X, Hirasawa K, Knuuti J, Marsan NA, Delgado V, van der Bijl P, Bax JJ
Background: Cardiac resynchronization therapy (CRT) candidates often present with significant mitral and tricuspid regurgitation, pulmonary hypertension and right ventricular dysfunction when referred for device implantation. This study investigated the prognostic value of a novel cardiac staging system, based on the extent of cardiac remodeling prior to implantation. Methods: Data were collected from an ongoing registry of CRT recipients. Patients were divided into 4 groups according to the ext...
Abstract
