9618 results
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
Annals of surgery,
Volume 271, Issue 4, 1 1 2020, Pages 781-789
Variation in Surgical Treatment of Abdominal Aortic Aneurysms With Small Aortic Diameters in the Netherlands.
Karthaus EG, Vahl A, van der Werf LR, Elsman BHP, Van Herwaarden JA, Wouters MWJM, Hamming JF
Objective: To evaluate reasons to deviate from aneurysm diameter thresholds, and focus on the difference in how Dutch vascular surgical units (VSUs) perceive their deviation and their actual deviation. Background: Guidelines recommend surgical treatment for asymptomatic abdominal aortic aneurysms (AAAs) with a diameter of at least 55 mm for men and 50 mm for women. We evaluate reasons to deviate from these guidelines, and focus on the difference in how Dutch vascular surgical units (VSUs) percei...
Abstract
Cited 63 times since 2020 (11.7 per year)
source: EuropePMC
JAMA network open,
Volume 3, Issue 4, 1 1 2020, Pages e202165
Effect of Smartphone-Enabled Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial Infarction: A Randomized Clinical Trial.
Treskes RW, van Winden LAM, van Keulen N, van der Velde ET, Beeres SLMA, Atsma DE, Schalij MJ
Importance: Smart technology via smartphone-compatible devices might improve blood pressure (BP) regulation in patients after myocardial infarction. Objectives: To investigate whether smart technology in clinical practice can improve BP regulation and to evaluate the feasibility of such an intervention. Design, setting, and participants: This study was an investigator-initiated, single-center, nonblinded, feasibility, randomized clinical trial conducted at the Department of Cardiology of the Lei...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 57, Issue 4, 1 1 2020, Pages 815
Concomitant aortic root enlargement is perhaps safe, but is it also effective?
Vriesendorp MD, de Lind van Wijngaarden RAF, Klautz RJM
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 67, 1 1 2020, Pages 346-353
Vascular Surgeons' Views on Ejaculation Disorders After Abdominal Aortic Surgery: Results of a Dutch Survey.
van Schaik J, van der Vorst JR, Hamming JF, Elzevier HW, Nicolai MPJ
Background: The aim of this study is to evaluate vascular surgeons' knowledge and appreciation of ejaculatory dysfunction after open aortic aneurysm repair and the knowledge of possible nerve-preserving techniques. Methods: A Dutch national survey was conducted on sexual counseling in the case of open aortic surgery. For this purpose, a designed questionnaire based on a review of the literature in the field and on other surveys aiming to analyze care for sexual health by medical specialists...
Abstract
Cited 49 times since 2020 (9.1 per year)
source: EuropePMC
Alimentary pharmacology & therapeutics,
Volume 51, Issue 9, 1 1 2020, Pages 880-888
Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry.
Biemans VBC, Sleutjes JAM, de Vries AC, Bodelier AGL, Dijkstra G, Oldenburg B, Löwenberg M, van Bodegraven AA, van der Meulen-de Jong AE, de Boer NKH, Srivastava N, West RL, Römkens TEH, Horjus Talabur Horje CS, Jansen JM, van der Woude CJ, Hoekstra J, Weersma RK, van Schaik FDM, Hoentjen F, Pierik MJ, Dutch Initiative on Crohn and Colitis (ICC)
Background: Tofacitinib is a Janus kinase inhibitor approved for the treatment of ulcerative colitis (UC). Aim: To evaluate effectiveness, safety and use of tofacitinib in daily practice. Methods: UC patients initiating tofacitinib were prospectively enrolled in 15 hospitals in the Netherlands. Corticosteroid-free clinical remission (short clinical colitis activity index [SCCAI] ≤2), biochemical remission (faecal calprotectin level ≤250 µg/g), combined corticosteroid-free clinical and biochemica...
Abstract
Cited 6 times since 2020 (1.1 per year)
source: EuropePMC
Perception,
Volume 49, Issue 4, 1 1 2020, Pages 484-487
When Is Moving a Cursor With a Computer Mouse Intuitive?
Brenner E, de Graaf ML, Stam MJ, Schonwetter M, Smeets JBJ, van Beers RJ
Abstract
Cited 4 times since 2020 (0.7 per year)
source: EuropePMC
Journal of graduate medical education,
Volume 12, Issue 2, 1 1 2020, Pages 153-158
E-ASSESS: Creating an EPA Assessment Tool for Structured Simulated Emergency Scenarios.
Andler C, Daya S, Kowalek K, Boscardin C, van Schaik SM
Background: The entrustable professional activity (EPA) assessment framework allows supervisors to assign entrustment levels to physician trainees for specific activities. Limited opportunity for direct observation of trainees hampers entrustment decisions, in particular for infrequently performed activities. Simulation allows for direct observation, so tools to assess performance of EPAs in simulation could potentially provide additional data to complement clinical assessments. Objective: We de...
Abstract
Cited 21 times since 2020 (3.9 per year)
source: EuropePMC
Cardiovascular research,
Volume 116, Issue 5, 1 1 2020, Pages 931-943
Stress-induced remodelling of the mitral valve: a model for leaflet thickening and superimposed tissue formation in mitral valve disease.
Kruithof BPT, Paardekooper L, Hiemstra YL, Goumans MJ, Palmen M, Delgado V, Klautz RJM, Ajmone Marsan N
Aims: In mitral valve prolapse (MVP), leaflet thickening has recently been suggested to be due, in addition to a myxomatous degeneration, to the presence of a superimposed tissue (SIT), defined as an additional fibrous layer on top of the original leaflet. The mechanisms of SIT formation are currently unknown. We hypothesized that SIT formation would result from excessive leaflet stress and we used a unique ex vivo model to assess the correlation between leaflet remodelling and the type and loca...
Abstract
Cited 21 times since 2020 (3.9 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 7, 31 5 2020, Pages 43
Multicellular <i>In vitro</i> Models of Cardiac Arrhythmias: Focus on Atrial Fibrillation.
van Gorp PRR, Trines SA, Pijnappels DA, de Vries AAF
Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice with a large socioeconomic impact due to its associated morbidity, mortality, reduction in quality of life and health care costs. Currently, antiarrhythmic drug therapy is the first line of treatment for most symptomatic AF patients, despite its limited efficacy, the risk of inducing potentially life-threating ventricular tachyarrhythmias as well as other side effects. Alternative, in-hospital treatment modalitie...
Abstract
Nature communications,
Volume 11, Issue 1, 31 5 2020, Pages 1702
Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies.
Hagenbeek FA, Pool R, van Dongen J, Draisma HM, Jan Hottenga J, Willemsen G, Abdellaoui A, Fedko IO, den Braber A, Visser PJ, de Geus EJCN, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, van Duijn CM, BBMRI Metabolomics Consortium, Harms AC, Hankemeier T, Bartels M, Nivard MG, Boomsma DI
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Abstract
Cited 107 times since 2020 (19.8 per year)
source: EuropePMC
Circulation,
Volume 141, Issue 20, 29 5 2020, Pages 1608-1617
Peripheral Artery Disease and Venous Thromboembolic Events After Acute Coronary Syndrome: Role of Lipoprotein(a) and Modification by Alirocumab: Prespecified Analysis of the ODYSSEY OUTCOMES Randomized Clinical Trial.
Schwartz GG, Steg PG, Szarek M, Bittner VA, Diaz R, Goodman SG, Kim YU, Jukema JW, Pordy R, Roe MT, White HD, Bhatt DL, ODYSSEY OUTCOMES Committees and Investigators*
Background: Patients with acute coronary syndrome are at risk for peripheral artery disease (PAD) events and venous thromboembolism (VTE). PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce lipoprotein(a) and low-density lipoprotein cholesterol (LDL-C) levels. Our objective was to ascertain whether PCSK9 inhibition reduces the risk of PAD events or VTE after acute coronary syndrome, and if such effects are related to levels of lipoprotein(a) or LDL-C. Methods: This was a pre...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 6, Issue 4, 29 5 2020, Pages 461-462
Whole Heart Histology: A Method for the Direct Integration of Histology With Electrophysiological and Imaging Data.
Glashan CA, Tofig BJ, Tao Q, Blom SA, Sørensen JCH, Zeppenfeld K, Kristiansen SB
Abstract
Cited 9 times since 2020 (1.7 per year)
source: EuropePMC
Cells,
Volume 9, Issue 4, 29 5 2020, Pages E824
Loss of Endothelial Glycocalyx Hyaluronan Impairs Endothelial Stability and Adaptive Vascular Remodeling After Arterial Ischemia.
Wang G, de Vries MR, Sol WMPJ, van Oeveren-Rietdijk AM, de Boer HC, van Zonneveld AJ, Quax PHA, Rabelink TJ, van den Berg BM
We recently reported that loss of hyaluronan (HA) from the endothelial glycocalyx leads to loss of vessel stability in specific microcirculatory vascular beds. Here we hypothesized that such derangements in the glycocalyx may also impair the adaptive response to vascular ischemia. Endothelial specific conditional hyaluronan synthase 2-KO (Has2-cKO) mice revealed reduced endothelial HA expression and lower hindlimb perfusion at baseline compared to control mice. After a single ligation of the com...
Abstract
Cited 165 times since 2020 (30.6 per year)
source: EuropePMC
The New England journal of medicine,
Volume 382, Issue 18, 29 5 2020, Pages 1696-1707
Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.
Nijenhuis VJ, Brouwer J, Delewi R, Hermanides RS, Holvoet W, Dubois CLF, Frambach P, De Bruyne B, van Houwelingen GK, Van Der Heyden JAS, Toušek P, van der Kley F, Buysschaert I, Schotborgh CE, Ferdinande B, van der Harst P, Roosen J, Peper J, Thielen FWF, Veenstra L, Chan Pin Yin DRPP, Swaans MJ, Rensing BJWM, van 't Hof AWJ, Timmers L, Kelder JC, Stella PR, Baan J, Ten Berg JM
Background: The roles of anticoagulation alone or with an antiplatelet agent after transcatheter aortic-valve implantation (TAVI) have not been well studied. Methods: We performed a randomized trial of clopidogrel in patients undergoing TAVI who were receiving oral anticoagulation for appropriate indications. Patients were assigned before TAVI in a 1:1 ratio not to receive clopidogrel or to receive clopidogrel for 3 months. The two primary outcomes were all bleeding and non-procedure-related ble...
Abstract
Cited 23 times since 2020 (4.3 per year)
source: EuropePMC
The Journal of arthroplasty,
Volume 35, Issue 8, 27 4 2020, Pages 1986-1992
Predictors of (Un)successful Same-Day Discharge in Selected Patients Following Outpatient Hip and Knee Arthroplasty.
Keulen MHF, Asselberghs S, Boonen B, Hendrickx RPM, van Haaren EH, Schotanus MGM
Background: It is generally accepted that only selected patients are suitable for outpatient joint arthroplasty (OJA); however, no consensus exists on the optimal selection criteria. We believe patients undergoing OJA should undergo risk stratification and mitigation in an attempt to optimize quality and minimize costs. Methods: Patient factors of 525 patients who were selected to have primary elective unicompartmental knee arthroplasty (N = 158), total knee arthroplasty (N = 277), or total hip...
Abstract
Genes,
Volume 11, Issue 4, 27 4 2020, Pages E358
Influence of Genetic Variation in <i>COMT</i> on Cisplatin-Induced Nephrotoxicity in Cancer Patients.
Agema BC, Koolen SLW, With M, Doorn NV, Heersche N, Hoop EO, Visser S, Aerts JGJV, Bins S, Schaik RHNV, Mathijssen RHJ
Cisplatin is a chemotherapeutic agent widely used for multiple indications. Unfortunately, in a substantial set of patients treated with cisplatin, dose-limiting acute kidney injury (AKI) occurs. Here, we assessed the association of 3 catechol-O-methyltransferase (COMT) single nucleotide polymorphisms (SNPs) with increased cisplatin-induced nephrotoxicity. In total, 551 patients were genotyped for the 1947 G>A (Val158Met, rs4680), c.615 + 310 C>T (rs4646316), and c.616 - 367 C>T (rs9332...
Abstract
Cited 8 times since 2020 (1.5 per year)
source: EuropePMC
Journal of clinical medicine,
Volume 9, Issue 4, 26 4 2020, Pages E911
Ventricular Repolarization is Associated with Cognitive Function, but Not with Cognitive Decline and Brain Magnetic Resonance Imaging (MRI) Measurements in Older Adults.
Zonneveld MH, Noordam R, Grond JV, Sabayan B, Mooijaart SP, Mcfarlane PW, Jukema JW, Trompet S
We aimed to investigate the cross-sectional and longitudinal associations of electrocardiogram (ECG)-based QT, QTc, JT, JTc, and QRS intervals with cognitive function and brain magnetic resonance imaging (MRI) measurements in a cohort of older individuals at increased risk for cardiovascular disease, but free of known arrhythmias. We studied 4627 participants (54% female, mean age 75 years) enrolled in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Ten-second ECGs were co...
Abstract
Cited 23 times since 2020 (4.3 per year)
source: EuropePMC
Current opinion in cell biology,
Volume 64, 26 4 2020, Pages 58-66
How to maintain the genome in nuclear space.
Mitrentsi I, Yilmaz D, Soutoglou E
Genomic instability can be life-threatening. The fine balance between error-free and mutagenic DNA repair pathways is essential for maintaining genome integrity. Recent advances in DNA double-strand break induction and detection techniques have allowed the investigation of DNA damage and repair in the context of the highly complex nuclear structure. These studies have revealed that the 3D genome folding, nuclear compartmentalization and cytoskeletal components control the spatial distribution of...
Abstract
Cited 14 times since 2020 (2.6 per year)
source: EuropePMC
Journal of clinical medicine,
Volume 9, Issue 4, 26 4 2020, Pages E908
The Development of the Ascending Aortic Wall in Tricuspid and Bicuspid Aortic Valve: A Process from Maturation to Degeneration.
Grewal N, Gittenberger-de Groot AC, Thusen JV, Wisse LJ, Bartelings MM, DeRuiter MC, Klautz RJM, Poelmann RE
Background: Patients with a bicuspid aortic valve (BAV) have an increased risk for aortic dilation and dissection. In this study, we provide a histological stratification of the developing aorta in the tricuspid aortic valve (TAV) and the BAV populations as a reference for future studies on aortopathy and related syndromes. Methods: Non-dilated TAV and BAV ascending aortic wall samples were collected, including 60 TAV (embryonic-70 years) and 32 BAV specimens (fetal-72 years, categorized in eigh...
Abstract
Cited 9 times since 2020 (1.7 per year)
source: EuropePMC
JACC. Basic to translational science,
Volume 5, Issue 4, 25 4 2020, Pages 360-373
Therapeutic Antibody Against Phosphorylcholine Preserves Coronary Function and Attenuates Vascular <sup>18</sup>F-FDG Uptake in Atherosclerotic Mice.
Ståhle M, Silvola JMU, Hellberg S, de Vries M, Quax PHA, Kroon J, Rinne P, de Jong A, Liljenbäck H, Savisto N, Wickman A, Stroes ESG, Ylä-Herttuala S, Saukko P, Abrahamsson T, Pettersson K, Knuuti J, Roivainen A, Saraste A
This study showed that treatment with a therapeutic monoclonal immunoglobulin-G1 antibody against phosphorylcholine on oxidized phospholipids preserves coronary flow reserve and attenuates atherosclerotic inflammation as determined by the uptake of 18F-fluorodeoxyglucose in atherosclerotic mice. The noninvasive imaging techniques represent translational tools to assess the efficacy of phosphorylcholine-targeted therapy on coronary artery function and atherosclerosis in clinical studies.
Abstract
