6128 results
Cited 57 times since 2007 (3.1 per year)
source: EuropePMC
Circulation,
Volume 115, Issue 4, 22 4 2007, Pages 493-500
Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation.
Pires NM, Pols TW, de Vries MR, van Tiel CM, Bonta PI, Vos M, Arkenbout EK, Pannekoek H, Jukema JW, Quax PH, de Vries CJ
Background: Restenosis is a common complication after percutaneous coronary interventions and is characterized by excessive proliferation of vascular smooth muscle cells (SMCs). We have shown that the nuclear receptor Nur77 protects against SMC-rich lesion formation, and it has been demonstrated that 6-mercaptopurine (6-MP) enhances Nur77 activity. We hypothesized that 6-MP inhibits neointima formation through activation of Nur77. Methods and results: It is demonstrated that 6-MP increases Nur77...
Abstract
Cited 1 times since 2007 (0.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 49, Issue 4, 12 2 2007, Pages 502-508
Highlights of the 2006 Scientific sessions of the American Society of Nuclear Cardiology: Montreal, Canada, September 7 to 10, 2006.
Bax JJ, Abbott BG, Beanlands RS, Bengel F, Berman DS, Garcia EV, Hendel RC, Mieres JH, Shaw LJ, Wackers FJ
Abstract
Cited 22 times since 2007 (1.2 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 34, Issue 6, 10 2 2007, Pages 900-909
Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: validation of an elastic surface model approach in comparison to cardiac magnetic resonance imaging, 4D-MSPECT and QGS.
Stegger L, Lipke CS, Kies P, Nowak B, Schober O, Buell U, Schäfers M, Schaefer WM
Purpose: The segmentation algorithm ESM based on an elastic surface model was validated for the assessment of left ventricular volumes and ejection fraction from ECG-gated myocardial perfusion SPECT. Additionally, it was compared with the commercially available quantification packages 4D-MSPECT and QGS. Cardiac MRI was used as the reference method. Methods: SPECT and MRI were performed on 70 consecutive patients with suspected or proven coronary artery disease. End-diastolic (EDV) and end-systol...
Abstract
Cited 76 times since 2007 (4.2 per year)
source: EuropePMC
Circulation,
Volume 115, Issue 3, 8 2 2007, Pages 326-332
Cyclooxygenase-2 inhibition increases mortality, enhances left ventricular remodeling, and impairs systolic function after myocardial infarction in the pig.
Timmers L, Sluijter JP, Verlaan CW, Steendijk P, Cramer MJ, Emons M, Strijder C, Gründeman PF, Sze SK, Hua L, Piek JJ, Borst C, Pasterkamp G, de Kleijn DP
Background: Cyclooxygenase (COX)-2 expression in the heart increases after myocardial infarction (MI). In murine models of MI, COX-2 inhibition preserves left ventricular dimensions and function. We studied the effect of selective COX-2 inhibition on left ventricular remodeling and function after MI in a pig model. Methods and results: Twenty-two pigs were assigned to COX-2 inhibition with a COX-2 inhibitor (COX-2i; celecoxib 400 mg twice daily; n=14) or a control group (n=8). MI was induced by...
Abstract
Cited 4 times since 2007 (0.2 per year)
source: EuropePMC
European radiology,
Volume 17, Issue 6, 6 1 2007, Pages 1422-1432
Molecular cardiovascular imaging using scintigraphic methods.
Stegger L, Schäfers K, Kopka K, Wagner S, Hermann S, Kies P, Law M, Schober O, Schäfers M
Molecular cardiovascular imaging plays an increasingly important role both in basic research and in clinical diagnosis. Scintigraphic methods have long been used to study pathophysiological changes on a cellular and molecular level, and they are likely to remain important molecular imaging modalities in the foreseeable future. This article provides an overview over current developments in cardiovascular molecular imaging using scintigraphic methods. The focus lies on imaging of cardiac innervati...
Abstract
Cited 174 times since 2007 (9.6 per year)
source: EuropePMC
The American journal of cardiology,
Volume 99, Issue 5, 4 1 2007, Pages 657-660
Effect of total scar burden on contrast-enhanced magnetic resonance imaging on response to cardiac resynchronization therapy.
Ypenburg C, Roes SD, Bleeker GB, Kaandorp TA, de Roos A, Schalij MJ, van der Wall EE, Bax JJ
It was shown that improvement in left ventricular (LV) function and reverse remodeling after cardiac resynchronization therapy (CRT) were greater in patients with nonischemic cardiomyopathy than in those with ischemic cardiomyopathy. The aim of this study is to evaluate the influence of scar burden on response to CRT. We included 34 patients with ischemic cardiomyopathy (New York Heart Association class 3.1 +/- 0.4, LV ejection fraction 23 +/- 7%). Contrast-enhanced magnetic resonance imaging wa...
Abstract
Cited 82 times since 2007 (4.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 99, Issue 4, 2 1 2007, Pages 554-557
Intrathoracic impedance monitoring to predict decompensated heart failure.
Ypenburg C, Bax JJ, van der Wall EE, Schalij MJ, van Erven L
Intrathoracic impedance measurement has been introduced in the InSync Sentry biventricular implantable cardioverter-defibrillator and may permit the early identification of pulmonary fluid accumulation secondary to left-sided heart failure (HF). An audible alarm (the OptiVol alert) can be triggered when the impedance index increases to greater than a predefined level of 60 Omega . day. The aim of this study was to evaluate the clinical value of the OptiVol alert and its prediction for decompensa...
Abstract
Cited 6 times since 2007 (0.3 per year)
source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,
Volume 9, Issue 6, 1 1 2007, Pages 877-882
Tissue cardiovascular magnetic resonance demonstrates regional diastolic dysfunction in remote tissue early after inferior myocardial infarction.
Paelinck BP, Vrints CJ, Bax JJ, Bosmans JM, de Roos A, Lamb HJ
Purpose: To investigate regional diastolic and systolic function using tissue cardiovascular magnetic resonance (CMR), early after transmural myocardial infarction of the inferior wall due to single proximal right coronary artery disease. Materials and methods: Velocity encoded CMR was used to measure early diastolic transmitral flow velocity (E), and regional, longitudinal, myocardial systolic (Sa) and early diastolic (Ea) velocities (tissue CMR) in 15 patients with a recent transmural inferior...
Abstract
Cited 13 times since 2007 (0.7 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 14, Issue 1, 1 1 2007, Pages 75-81
Prognostic value of gated SPECT in patients with left bundle branch block.
America YG, Bax JJ, Boersma E, Stokkel M, van der Wall EE
Background: The aim of this study was to assess the prognostic value of quantitative gated technetium 99m tetrofosmin single photon emission computed tomography (SPECT) imaging in patients with left bundle branch block (LBBB). Methods and results: We followed up 101 consecutive patients with LBBB using Tc-99m tetrofosmin gated SPECT imaging. The mean follow-up was 1.24 years (maximum, 2.48 years). Hard endpoints were all-cause death and acute myocardial infarction. Event-free survival curves wer...
Abstract
Cited 116 times since 2007 (6.4 per year)
source: EuropePMC
European journal of endocrinology,
Volume 156, Issue 1, 1 1 2007, Pages 137-142
Increased preoperative glucose levels are associated with perioperative mortality in patients undergoing noncardiac, nonvascular surgery.
Noordzij PG, Boersma E, Schreiner F, Kertai MD, Feringa HH, Dunkelgrun M, Bax JJ, Klein J, Poldermans D
Objective: To determine the relationship between preoperative glucose levels and perioperative mortality in noncardiac, nonvascular surgery. Research design and methods: We performed a case-control study in a cohort of 108 593 patients who underwent noncardiac surgery at the Erasmus MC during 1991-2001. Cases were 989 patients who underwent elective noncardiac, nonvascular surgery and died within 30 days during hospital stay. From the remaining patients, 1879 matched controls (age, sex, calendar...
Abstract
Cited 19 times since 2007 (1 per year)
source: EuropePMC
Anesthesia and analgesia,
Volume 104, Issue 1, 1 1 2007, Pages 8-10
Pro: Beta-blockers are indicated for patients at risk for cardiac complications undergoing noncardiac surgery.
Schouten O, Bax JJ, Dunkelgrun M, Feringa HH, Poldermans D
Abstract
Cited 1 times since 2007 (0.1 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 9, Issue 1, 1 1 2007, Pages 48-9; author reply 61
Biventricular pacing and transmural dispersion of the repolarization.
Swenne CA, van Huysduynen BH, Bax JJ, Bleeker GB, Draisma HH, van Erven L, Molhoek SG, van de Vooren H, van der Wall EE, Schalij MJ
Abstract
Cited 25 times since 2007 (1.4 per year)
source: EuropePMC
Current pharmaceutical design,
Volume 13, Issue 10, 1 1 2007, Pages 1039-1052
Chemokines and atherosclerotic plaque progression: towards therapeutic targeting?
Kraaijeveld AO, de Jager SC, van Berkel TJ, Biessen EA, Jukema JW
Atherosclerosis is currently viewed as an inflammatory disease in which the initiation and progression of the atherosclerotic plaque towards a rupture prone, unstable plaque is driven by leukocyte recruitment mediated by various inflammatory mediators. Recently, interest in chemotactic cytokines or chemokines with regard to atherosclerosis has been growing as chemokines mediate the influx of leukocytes that is typical of atherothrombosis. The activity of the majority of chemokines is overlapping...
Abstract
Cited 1 times since 2007 (0.1 per year)
source: EuropePMC
The American heart hospital journal,
Volume 5, Issue 2, 1 1 2007, Pages 110-113
What is the value of QRS duration for the prediction of response to cardiac resynchronization therapy?
Bleeker GB, Bax JJ
Abstract
Critical care medicine,
Volume 35, Issue 1, 1 1 2007, Pages 321-322
Effect of thoracic epidural anesthesia on right ventricular function and homeometric autoregulation.
Steendijk P
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 15, Issue 7-8, 1 1 2007, Pages 247
Different aspects of coronary artery disease.
Jukema JW
Abstract
Cited 4 times since 2007 (0.2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 93, Issue 1, 1 1 2007, Pages 113-114
Feasibility of trans-endocardial cell transplantation in chronic ischaemia.
Beeres SL, Bax JJ, Zeppenfeld K, Dibbets-Schneider P, Stokkel MP, Fibbe WE, van der Wall EE, Schalij MJ, Atsma DE
Abstract
Cited 160 times since 2007 (8.8 per year)
source: EuropePMC
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
Volume 22, Issue 1, 1 1 2007, Pages 19-28
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation.
van Bezooijen RL, Svensson JP, Eefting D, Visser A, van der Horst G, Karperien M, Quax PH, Vrieling H, Papapoulos SE, ten Dijke P, Löwik CW
Unlabelled: Sclerostin is an osteocyte-derived negative regulator of bone formation. It inhibits BMP-stimulated bone formation both in vitro and in vivo but has no direct effect on BMP signaling. Instead, sclerostin inhibits Wnt signaling that is required for BMP-stimulated osteoblastic differentiation. Introduction: Sclerostin is a member of the Dan family of glycoproteins of which many members have been reported to antagonize BMP activity. Sclerostin has been shown to inhibit BMP-stimulated bo...
Abstract
Cited 5 times since 2007 (0.3 per year)
source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,
Volume 9, Issue 3, 1 1 2007, Pages 557-563
Validation of a high-resolution, phase contrast cardiovascular magnetic resonance sequence for evaluation of flow in coronary artery bypass grafts.
Salm LP, Schuijf JD, Lamb HJ, Bax JJ, Vliegen HW, Jukema JW, van der Wall EE, de Roos A, Doornbos J
The aim was to validate a magnetic resonance high-resolution, phase-contrast sequence for quantifying flow in small and large vessels and to demonstrate its feasibility to measure flow in coronary artery bypass grafts. A breathhold, echo planar imaging (EPI) sequence was developed and validated in a flow phantom using a fast field echo (FFE) sequence as reference. In 17 volunteers aortic flow was measured using both sequences. In 5 patients flow in the left internal mammary artery (LIMA) and aor...
Abstract
Cited 5 times since 2007 (0.3 per year)
source: EuropePMC
Acute cardiac care,
Volume 9, Issue 4, 1 1 2007, Pages 243-251
Intramyocardial bone marrow cell transplantation and the progression of coronary atherosclerosis in patients with chronic myocardial ischemia.
Beeres SL, Bax JJ, Roes SD, Lamb HJ, Fibbe WE, De Roos A, Van Der Wall EE, Schalij MJ, Atsma DE
Background: Cell therapy has been proposed as a novel treatment strategy for patients with ischemic heart disease. However, two recent studies suggested that cardiac cell transplantation might aggravate coronary atherosclerosis. The aim of the current study was to assess whether intramyocardial bone marrow cell transplantation in patients with chronic myocardial ischemia is associated with progression of coronary atherosclerosis. Methods: In 30 patients with chronic ischemia, bone marrow was asp...
Abstract
