7965 results
Cited 6 times since 2013 (0.5 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 29, Issue 8, 27 4 2013, Pages 1829-1837
Association of atherosclerosis in the descending thoracic aorta with coronary artery disease on multi detector row computed tomography coronary angiography in patients with suspected coronary artery disease.
Roos CJ, Witkowska AJ, de Graaf MA, Veltman CE, Delgado V, de Grooth GJ, Jukema JW, Bax JJ, Scholte AJ
The association between atherosclerosis in the descending thoracic aorta (DTA) visualized on computed tomography coronary angiography (CTA) and coronary artery disease (CAD) has not been extensively explored. Therefore, a comprehensive analysis of DTA atherosclerosis on CTA was performed and the association of DTA atherosclerosis with CAD was evaluated in patients with suspected CAD. A total of 344 patients (54 ± 12 years, 54% men) with suspected CAD underwent CTA. CTA were classified based on C...
Abstract
Cited 589 times since 2013 (50.7 per year)
source: EuropePMC
Nature reviews. Clinical oncology,
Volume 10, Issue 9, 23 4 2013, Pages 507-518
Image-guided cancer surgery using near-infrared fluorescence.
Vahrmeijer AL, Hutteman M, van der Vorst JR, van de Velde CJ, Frangioni JV
Paradigm shifts in surgery arise when surgeons are empowered to perform surgery faster, better and less expensively than current standards. Optical imaging that exploits invisible near-infrared (NIR) fluorescent light (700-900 nm) has the potential to improve cancer surgery outcomes, minimize the time patients are under anaesthesia and lower health-care costs largely by way of its improved contrast and depth of tissue penetration relative to visible light. Accordingly, the past few years have wi...
Abstract
Cited 90 times since 2013 (7.8 per year)
source: EuropePMC
The Journal of physiology,
Volume 591, Issue 17, 22 4 2013, Pages 4189-4206
Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs.
Jost N, Virág L, Comtois P, Ordög B, Szuts V, Seprényi G, Bitay M, Kohajda Z, Koncz I, Nagy N, Szél T, Magyar J, Kovács M, Puskás LG, Lengyel C, Wettwer E, Ravens U, Nánási PP, Papp JG, Varró A, Nattel S
The species-specific determinants of repolarization are poorly understood. This study compared the contribution of various currents to cardiac repolarization in canine and human ventricle. Conventional microelectrode, whole-cell patch-clamp, molecular biological and mathematical modelling techniques were used. Selective IKr block (50-100 nmol l(-1) dofetilide) lengthened AP duration at 90% of repolarization (APD90) >3-fold more in human than dog, suggesting smaller repolarization reserve in h...
Abstract
Cited 25 times since 2013 (2.2 per year)
source: EuropePMC
Seminars in fetal & neonatal medicine,
Volume 18, Issue 5, 22 4 2013, Pages 237-244
Embryology of the heart and its impact on understanding fetal and neonatal heart disease.
Gittenberger-de Groot AC, Bartelings MM, Poelmann RE, Haak MC, Jongbloed MR
Heart development is a complex process during which the heart needs to transform from a single tube towards a fully septated heart with four chambers and a separated outflow tract. Several major events contribute to this process, that largely overlap in time. Abnormal heart development results in congenital heart disease, which has an estimated incidence of 1% of liveborn children. Eighty percent of cases of congenital heart disease are considered to have a multifactoral developmental background...
Abstract
Cited 31 times since 2013 (2.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 112, Issue 8, 19 3 2013, Pages 1197-1206
Arrhythmogenic right ventricular dysplasia/cardiomyopathy according to revised 2010 task force criteria with inclusion of non-desmosomal phospholamban mutation carriers.
Groeneweg JA, van der Zwaag PA, Olde Nordkamp LR, Bikker H, Jongbloed JD, Jongbloed R, Wiesfeld AC, Cox MG, van der Heijden JF, Atsma DE, de Boer K, Doevendans PA, Vink A, van Veen TA, Dooijes D, van den Berg MP, Wilde AA, van Tintelen JP, Hauer RN
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is frequently associated with desmosomal mutations. However, nondesmosomal mutations may be involved. The aim of this study was to assess the contribution of a phospholamban (PLN) gene mutation to ARVD/C diagnosis according to the revised 2010 task force criteria (TFC). In 142 Dutch patients (106 men, mean age 51 ± 13 years) with proven ARVD/C (fulfillment of 2010 TFC for diagnosis), 5 known desmosomal genes (PKP2, DSP, DSC2, DSG...
Abstract
Cited 10 times since 2013 (0.9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 15, Issue 2, 18 3 2013, Pages 189-194
Ventricular response to dobutamine stress relates to the change in peak oxygen uptake during the 5-year follow-up in young patients with repaired tetralogy of Fallot.
Luijnenburg SE, Mekic S, van den Berg J, van der Geest RJ, Moelker A, Roos-Hesselink JW, Bogers AJ, de Rijke YB, Strengers JL, Mulder BJ, Vliegen HW, Helbing WA
Aims: To evaluate the additional value of dobutamine stress testing in patients with repaired tetralogy of Fallot (TOF) by relating stress imaging parameters at baseline to relevant parameters of clinical condition and right ventricular (RV) size during a serial follow-up. Methods and results: We prospectively included 27 patients (14 ± 4 years at baseline), who were studied twice with a 5-year interval. Patients underwent cardiovascular magnetic resonance imaging to assess RV systolic and diast...
Abstract
Cited 7 times since 2013 (0.6 per year)
source: EuropePMC
Archives of orthopaedic and trauma surgery,
Volume 133, Issue 10, 17 3 2013, Pages 1407-1414
Early conversion to below-elbow cast for non-reduced diaphyseal both-bone forearm fractures in children is safe: preliminary results of a multicentre randomised controlled trial.
Colaris JW, Reijman M, Allema JH, Biter LU, Bloem RM, van de Ven CP, de Vries MR, Kerver AJ, Verhaar JA
Introduction: This multicentre randomised controlled trial was designed to explore whether 6 weeks above-elbow cast (AEC) or 3 weeks AEC followed by 3 weeks below-elbow cast (BEC) cause similar limitation of pronation and supination in non-reduced diaphyseal both-bone forearm fractures in children. Materials and methods: Children were randomly allocated to 6 weeks AEC or to 3 weeks AEC followed by 3 weeks BEC. The primary outcome was limitation of pronation and supination after 6 months. The sec...
Abstract
Cited 10 times since 2013 (0.9 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 96, Issue 4, 16 3 2013, Pages 1390-1397
Variation in coronary anatomy in adult patients late after arterial switch operation: a computed tomography coronary angiography study.
Veltman CE, Beeres SLMA, Kalkman DN, Kelder TP, Kiès P, Vliegen HW, Hazekamp MG, Delgado V, Kroft LJM, van der Wall EE, Gittenberger-de Groot AC, Scholte AJHA, Schalij MJ, Jongbloed MRM
Background: The arterial switch operation is the current treatment for transposition of the great arteries. Long-term outcome mainly depends on the patency of the transferred coronary arteries. This study assessed the presence of abnormal coronary findings and neoaortic root dilation late after arterial switch operation. Methods: In 30 adult patients after arterial switch operation (22 men, 22 ± 3 years), computed tomography angiography was performed to assess the coronary anatomy and abnormal c...
Abstract
Cited 46 times since 2013 (4 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 26, Issue 9, 13 2 2013, Pages 1053-1062
Left atrial function by two-dimensional speckle-tracking echocardiography in patients with severe organic mitral regurgitation: association with guidelines-based surgical indication and postoperative (long-term) survival.
Debonnaire P, Leong DP, Witkowski TG, Al Amri I, Joyce E, Katsanos S, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background: Left atrial (LA) mechanics in patients with severe mitral regurgitation (MR) remain largely unexplored. The aim of the present evaluation was to assess the effect of severe MR on LA function, its potential relation with conventional surgical indications, and long-term postoperative survival. Methods: Two-dimensional speckle-tracking strain and volumetric indices of LA reservoir, conduit, and contractile function were assessed in 121 patients with severe MR and 70 controls. Patients w...
Abstract
Cited 5 times since 2013 (0.4 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 15, Issue 12, 12 2 2013, Pages 1757-1762
Atrial-based pacing has no benefit over ventricular pacing in preventing atrial arrhythmias in adults with congenital heart disease.
Opic P, Yap SC, Van Kranenburg M, Van Dijk AP, Budts W, Vliegen HW, Van Erven L, Can A, Sahin G, De Groot NM, Witsenburg M, Roos-Hesselink JW
Aims: To determine whether atrial-based pacing prevents atrial arrhythmias in adults with congenital heart disease (CHD) compared with ventricular pacing. Methods and results: All adult CHD patients from four participating centres with a permanent pacemaker were identified. Patients with permanent atrial arrhythmias at pacemaker implantation and patients who received a pacemaker for treatment of drug-refractory atrial arrhythmias were excluded. The final study population consisted of 211 patient...
Abstract
Cited 18 times since 2013 (1.5 per year)
source: EuropePMC
PloS one,
Volume 8, Issue 7, 10 2 2013, Pages e67936
CT coronary angiography is feasible for the assessment of coronary artery disease in chronic dialysis patients, despite high average calcium scores.
de Bie MK, Buiten MS, Gaasbeek A, Boogers MJ, Roos CJ, Schuijf JD, Krol MJ, Rabelink TJ, Bax JJ, Schalij MJ, Jukema JW
Purpose: Significant obstructive coronary artery disease (CAD) is common in asymptomatic dialysis patients. Identifying these high risk patients is warranted and may improve the prognosis of this vulnerable patient group. Routine catheterization of incident dialysis patients has been proposed, but is considered too invasive. CT-angiography may therefore be more appropriate. However, extensive coronary calcification, often present in this patient group, might hamper adequate lumen evaluation. The...
Abstract
Cited 44 times since 2013 (3.8 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 62, Issue 13, 10 2 2013, Pages 1195-1202
Neurohormonal, structural, and functional recovery pattern after premature ventricular complex ablation is independent of structural heart disease status in patients with depressed left ventricular ejection fraction: a prospective multicenter study.
Penela D, Van Huls Van Taxis C, Van Huls Vans Taxis C, Aguinaga L, Fernández-Armenta J, Mont L, Castel MA, Heras M, Tolosana JM, Sitges M, Ordóñez A, Brugada J, Zeppenfeld K, Berruezo A
Objectives: This study aimed to assess the benefit after ablation of premature ventricular complexes (PVC) in patients with frequent PVC and left ventricular (LV) dysfunction, regardless of previous structural heart disease (SHD) diagnosis, PVC morphology, or estimated site of origin. Background: Ablation of PVC in patients with LV dysfunction is usually restricted to patients with suspected PVC-induced cardiomyopathy. Methods: Consecutive patients with frequent PVC and LV dysfunction accepted f...
Abstract
Cited 26 times since 2013 (2.2 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 62, Issue 10, 10 2 2013, Pages 926-936
Right ventricular end-diastolic volume combined with peak systolic blood pressure during exercise identifies patients at risk for complications in adults with a systemic right ventricle.
van der Bom T, Winter MM, Groenink M, Vliegen HW, Pieper PG, van Dijk AP, Sieswerda GT, Roos-Hesselink JW, Zwinderman AH, Mulder BJ, Bouma BJ
Objectives: The aim of this study was to identify which patients with a systemic right ventricle are at risk for clinical events. Background: In patients with congenitally or atrially corrected transposition of the great arteries, worsening of the systemic right ventricle is accompanied by clinical events such as clinical heart failure or the occurrence of arrhythmia. Methods: At baseline, all subjects underwent electrocardiography, echocardiography, cardiopulmonary exercise testing, and cardiov...
Abstract
Cited 21 times since 2013 (1.8 per year)
source: EuropePMC
Nucleic acids research,
Volume 41, Issue 17, 5 1 2013, Pages 8107-8125
Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis.
Trilling M, Bellora N, Rutkowski AJ, de Graaf M, Dickinson P, Robertson K, Prazeres da Costa O, Ghazal P, Friedel CC, Albà MM, Dölken L
Interferons (IFN) play a pivotal role in innate immunity, orchestrating a cell-intrinsic anti-pathogenic state and stimulating adaptive immune responses. The complex interplay between the primary response to IFNs and its modulation by positive and negative feedback loops is incompletely understood. Here, we implement the combination of high-resolution gene-expression profiling of nascent RNA with translational inhibition of secondary feedback by cycloheximide. Unexpectedly, this approach reveale...
Abstract
Cited 11 times since 2013 (0.9 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 36, Issue 11, 4 1 2013, Pages 1391-1401
Clinical, echocardiographic, and neurohormonal response to cardiac resynchronization therapy: are they interchangeable?
Hoogslag GE, Höke U, Thijssen J, Auger D, Marsan NA, Wolterbeek R, Holman ER, Schalij MJ, Bax JJ, Verwey HF, Delgado V
Background: The relationship between changes in N-terminal pro-brain natriuretic peptide (NT-proBNP) and echocardiographic or clinical definitions of response to cardiac resynchronization therapy (CRT) has not been evaluated. The aims of the present evaluation were to assess: (1) the relationship between changes in NT-proBNP after 6 months of CRT and clinical and echocardiographic responses; (2) the association between NT-proBNP changes and long-term outcome. Methods: In 170 patients treated wit...
Abstract
Cited 17 times since 2013 (1.5 per year)
source: EuropePMC
PloS one,
Volume 8, Issue 7, 2 1 2013, Pages e67923
TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation.
Karper JC, Ewing MM, de Vries MR, de Jager SC, Peters EA, de Boer HC, van Zonneveld AJ, Kuiper J, Huizinga EG, Brondijk TH, Jukema JW, Quax PH
Background: RP105 (CD180) is TLR4 homologue lacking the intracellular TLR4 signaling domain and acts a TLR accessory molecule and physiological inhibitor of TLR4-signaling. The role of RP105 in vascular remodeling, in particular post-interventional remodeling is unknown. Methods and results: TLR4 and RP105 are expressed on vascular smooth muscle cells (VSMC) as well as in the media of murine femoral artery segments as detected by qPCR and immunohistochemistry. Furthermore, the response to the TL...
Abstract
Cited 1 times since 2013 (0.1 per year)
source: EuropePMC
Iranian journal of basic medical sciences,
Volume 16, Issue 7, 1 1 2013, Pages 813-821
Generation of Helper Plasmids Encoding Mutant Adeno-associated Virus Type 2 Capsid Proteins with Increased Resistance against Proteasomal Degradation.
Ahmadiankia N, Neshati V, Neshati Z, Swildens J, de Vries AA
Objective(s): Adeno-associated virus type 2 (AAV2) vectors are widely used for both experimental and clinical gene therapy. A recent research has shown that the performance of these vectors can be greatly improved by substitution of specific surface-exposed tyrosine residues with phenylalanines. In this study, a fast and simple method is presented to generate AAV2 vector helper plasmids encoding capsid proteins with single, double or triple Y→F mutations. Materials and methods: A one-step, high-...
Abstract
Cited 13 times since 2013 (1.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 21, Issue 7-8, 1 1 2013, Pages 347-353
Different value of coronary calcium score to predict obstructive coronary artery disease in patients with and without moderate chronic kidney disease.
Yiu KH, de Graaf FR, van Velzen JE, Marsan NA, Roos CJ, de Bie MK, Tse HF, van der Wall EE, Schalij MJ, Bax JJ, Schuijf JD, Jukema JW
Purpose: The coronary calcium score (CCS) predicts significant coronary artery disease (CAD) in the general population. While moderate chronic kidney disease (CKD) is associated with high CCS, the use of CCS to predict significant CAD in these patients is unknown. Methods: A total of 704 patients underwent computed tomography coronary angiography for the assessment of CCS and CAD. Sixty-nine (10 %) patients had moderate CKD, defined by an estimated glomerular filtration rate (eGFR) between 30 an...
Abstract
Cited 16 times since 2013 (1.4 per year)
source: EuropePMC
Radiology,
Volume 269, Issue 2, 25 4 2013, Pages 370-377
Aortic disease in patients with Marfan syndrome: aortic volume assessment for surveillance.
den Hartog AW, Franken R, de Witte P, Radonic T, Marquering HA, van der Steen WE, Timmermans J, Scholte AJ, van den Berg MP, Zwinderman AH, Mulder BJ, Groenink M
Purpose: To assess the reproducibility of aortic volume estimates and to serially test their use in patients with Marfan syndrome. Materials and methods: The study was approved by the medical ethics committee and all subjects gave written informed consent. In 81 patients with Marfan syndrome and seven healthy control subjects, aortic volumes and diameters at baseline were estimated by means of contrast material-enhanced magnetic resonance (MR) imaging. At 3 years of follow-up, aortic expansion r...
Abstract
Cited 1001 times since 2013 (85.6 per year)
source: EuropePMC
European heart journal,
Volume 34, Issue 29, 24 4 2013, Pages 2281-2329
2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA).
Brignole M, Auricchio A, Baron-Esquivias G, Bordachar P, Boriani G, Breithardt OA, Cleland J, Deharo JC, Delgado V, Elliott PM, Gorenek B, Israel CW, Leclercq C, Linde C, Mont L, Padeletti L, Sutton R, Vardas PE, ESC Committee for Practice Guidelines (CPG), Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S, Document Reviewers, Kirchhof P, Blomstrom-Lundqvist C, Badano LP, Aliyev F, Bänsch D, Baumgartner H, Bsata W, Buser P, Charron P, Daubert JC, Dobreanu D, Faerestrand S, Hasdai D, Hoes AW, Le Heuzey JY, Mavrakis H, McDonagh T, Merino JL, Nawar MM, Nielsen JC, Pieske B, Poposka L, Ruschitzka F, Tendera M, Van Gelder IC, Wilson CM
Abstract
