9618 results
Cited 4 times since 2014 (0.4 per year)
source: EuropePMC
Mediators of inflammation,
Volume 2014, 6 1 2014, Pages 395278
Danger signals in cardiovascular disease.
Frantz S, Monaco C, Arslan F
Abstract
Cited 17 times since 2014 (1.5 per year)
source: EuropePMC
BMC neurology,
Volume 14, 4 1 2014, Pages 72
Deterioration after corticosteroids in CIDP may be associated with pure focal demyelination pattern.
Eftimov F, Liesdek MH, Verhamme C, van Schaik IN, PREDICT study group
Background: In the PREDICT study, a randomised controlled trial comparing dexamethasone with prednisolone in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), almost a quarter of patients deteriorated soon after starting treatment. The primary objective of this post-hoc analysis was to test the hypothesis that a focal demyelination pattern is associated with early deterioration after corticosteroid treatment and to explore whether various clinical characteristics ar...
Abstract
Cited 55 times since 2014 (4.8 per year)
source: EuropePMC
American heart journal,
Volume 168, Issue 1, 4 1 2014, Pages 45-52.e7
A metabolomic profile is associated with the risk of incident coronary heart disease.
Vaarhorst AA, Verhoeven A, Weller CM, Böhringer S, Göraler S, Meissner A, Deelder AM, Henneman P, Gorgels AP, van den Brandt PA, Schouten LJ, van Greevenbroek MM, Merry AH, Verschuren WM, van den Maagdenberg AM, van Dijk KW, Isaacs A, Boomsma D, Oostra BA, van Duijn CM, Jukema JW, Boer JM, Feskens E, Heijmans BT, Slagboom PE
Background: Metabolomics, defined as the comprehensive identification and quantification of low-molecular-weight metabolites to be found in a biological sample, has been put forward as a potential tool for classifying individuals according to their risk of coronary heart disease (CHD). Here, we investigated whether a single-point blood measurement of the metabolome is associated with and predictive for the risk of CHD. Methods and results: We obtained proton nuclear magnetic resonance spectra in...
Abstract
Cited 54 times since 2014 (4.7 per year)
source: EuropePMC
Injury,
Volume 45, Issue 8, 4 1 2014, Pages 1224-1230
Circumstances leading to injurious falls in older men and women in the Netherlands.
Boyé ND, Mattace-Raso FU, Van der Velde N, Van Lieshout EM, De Vries OJ, Hartholt KA, Kerver AJ, Bruijninckx MM, Van der Cammen TJ, Patka P, Van Beeck EF, IMPROveFALL trial collaborators
Background: Fall-induced injuries in persons aged 65 years and older are a major public health problem. Data regarding circumstances leading to specific injuries, such as traumatic brain injury (TBI) and hip fractures in older adults are scarce. Objective: To investigate the activity distributions leading to indoor and outdoor falls requiring an emergency department (ED) visit, and those resulting in TBIs and hip fractures. Participants: 5880 older adults who visited the ED due to a fall. Method...
Abstract
Cited 3 times since 2014 (0.3 per year)
source: EuropePMC
Heart, lung & circulation,
Volume 23, Issue 8, 2 1 2014, Pages e169-71
Transcatheter mitral valve repair in osteogenesis imperfecta associated mitral valve regurgitation.
van der Kley F, Delgado V, Ajmone Marsan N, Schalij MJ
Objectives: Osteogenesis imperfecta is associated with increased prevalence of significant mitral valve regurgitation. Surgical mitral valve repair and replacement are feasible but are associated with increased risk of bleeding and dehiscence of implanted valves may occur more frequently. The present case report describes the outcomes of transcatheter mitral valve repair in a patient with osteogenesis imperfecta. Patients/methods: A 60 year-old patient with osteogenesis imperfecta and associated...
Abstract
Cited 2 times since 2014 (0.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 21, Issue 2, 1 1 2014, Pages 245-247
The importance of heart rate response during myocardial perfusion imaging.
Bax JJ, Delgado V
Abstract
Cited 30 times since 2014 (2.6 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 16 Suppl 1, 1 1 2014, Pages i1-78
Statistics on the use of cardiac electronic devices and electrophysiological procedures in 55 ESC countries: 2013 report from the European Heart Rhythm Association (EHRA).
Arribas F, Auricchio A, Boriani G, Brugada J, Deharo JC, Hindriks G, Kuck KH, Merino JL, Vardas P, Wolpert C, Zeppenfeld K
Abstract
Cited 152 times since 2014 (13.3 per year)
source: EuropePMC
JAMA,
Volume 311, Issue 15, 1 1 2014, Pages 1515-1525
Effect of aleglitazar on cardiovascular outcomes after acute coronary syndrome in patients with type 2 diabetes mellitus: the AleCardio randomized clinical trial.
Lincoff AM, Tardif JC, Schwartz GG, Nicholls SJ, Rydén L, Neal B, Malmberg K, Wedel H, Buse JB, Henry RR, Weichert A, Cannata R, Svensson A, Volz D, Grobbee DE, AleCardio Investigators
Importance: No therapy directed against diabetes has been shown to unequivocally reduce the excess risk of cardiovascular complications. Aleglitazar is a dual agonist of peroxisome proliferator-activated receptors with insulin-sensitizing and glucose-lowering actions and favorable effects on lipid profiles. Objective: To determine whether the addition of aleglitazar to standard medical therapy reduces cardiovascular morbidity and mortality among patients with type 2 diabetes mellitus and a recen...
Abstract
Cited 40 times since 2014 (3.5 per year)
source: EuropePMC
The Journal of urology,
Volume 192, Issue 3, 1 1 2014, Pages 708-713
Combined chemohyperthermia: 10-year single center experience in 160 patients with nonmuscle invasive bladder cancer.
Arends TJ, van der Heijden AG, Witjes JA
Purpose: Nonmuscle invasive bladder cancer is characterized by a high recurrence rate. New adjuvant treatments are needed to decrease this high number of recurrences. We present the results of more than 10 years of experience with chemohyperthermia in patients with nonmuscle invasive bladder cancer. Materials and methods: Using standardized medical record forms we prospectively collected patient and tumor characteristics of patients treated with chemohyperthermia between 2002 and 2013. Median fo...
Abstract
Pharmacogenomics,
Volume 15, Issue 6, 1 1 2014, Pages 739-744
Conference scene: pharmacogenomics: from cell to clinic (part 2).
Siest G, Medeiros R, Melichar B, Stathopoulou M, Van Schaik RH, Cacabelos R, Abt PM, Monteiro C, Gurwitz D, Queiroz J, Mota-Filipe H, Ndiaye NC, Visvikis-Siest S
Second International ESPT Meeting Lisbon, Portugal, 26-28 September 2013 The second European Society of Pharmacogenomics and Theranostics (ESPT) conference was organized in Lisbon, Portugal, and attracted 250 participants from 37 different countries. The participants could listen to 50 oral presentations, participate in five lunch symposia and were able to view 83 posters and an exhibition. Part 1 of this Conference Scene was presented in the previous issue of Pharmacogenomics. This second part...
Abstract
Cited 5 times since 2014 (0.4 per year)
source: EuropePMC
JAMA,
Volume 311, Issue 14, 1 1 2014, Pages 1401-1402
A piece of my mind. Pimping Socrates.
van Schaik KD
Abstract
Cited 21 times since 2014 (1.8 per year)
source: EuropePMC
The American journal of cardiology,
Volume 113, Issue 12, 1 1 2014, Pages 1947-1955
Feasibility of an automated quantitative computed tomography angiography-derived risk score for risk stratification of patients with suspected coronary artery disease.
de Graaf MA, Broersen A, Ahmed W, Kitslaar PH, Dijkstra J, Kroft LJ, Delgado V, Bax JJ, Reiber JH, Scholte AJ
Coronary computed tomography angiography (CTA) has important prognostic value. Additionally, quantitative CTA (QCT) provides a more detailed accurate assessment of coronary artery disease (CAD) on CTA. Potentially, a risk score incorporating all quantitative stenosis parameters allows accurate risk stratification. Therefore, the purpose of this study was to determine if an automatic quantitative assessment of CAD using QCT combined into a CTA risk score allows risk stratification of patients. In...
Abstract
Pharmacogenomics,
Volume 15, Issue 5, 1 1 2014, Pages 593-599
Pharmacogenomics: from cell to clinic (Part 1).
Siest G, Medeiros R, Melichar B, Stathopoulou M, Van Schaik RH, Cacabelos R, Abt PM, Monteiro C, Gurwitz D, Queiroz J, Mota-Filipe H, Ndiaye NC, Visvikis-Siest S
The second international European Society of Pharmacogenomics and Theranostics (ESPT) conference was organized in Lisbon, Portugal, and attracted 250 participants from 37 different countries. The participants could listen to 50 oral presentations, participate in five lunch symposia and were able to view 83 posters and an exhibition. The first part of this Conference Scene will focus on the pharmacogenomics and biomarkers used in medical oncology, and in particular solid tumors. In addition, this...
Abstract
Cited 33 times since 2014 (2.9 per year)
source: EuropePMC
British journal of clinical pharmacology,
Volume 77, Issue 4, 1 1 2014, Pages 715-728
Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks.
Elens L, Bouamar R, Shuker N, Hesselink DA, van Gelder T, van Schaik RH
Pharmacogenetics has generated many expectations for its potential to individualize therapy proactively and improve medical care. However, despite the huge amount of reported genetic associations with either pharmacokinetics or pharmacodynamics of drugs, the translation into patient care is still slow. In fact, strong evidence for a substantial clinical benefit of pharmacogenetic testing is still limited, with a few exceptions. In kidney transplantation, established pharmacogenetic discoveries a...
Abstract
Cited 25 times since 2014 (2.2 per year)
source: EuropePMC
Therapeutic drug monitoring,
Volume 36, Issue 2, 1 1 2014, Pages 152-158
P450 oxidoreductase *28 (POR*28) and tacrolimus disposition in pediatric kidney transplant recipients--a pilot study.
Gijsen VM, van Schaik RH, Soldin OP, Soldin SJ, Nulman I, Koren G, de Wildt SN
Background: Both age and CYP3A5 genotype are important determinants of tacrolimus disposition in pediatric kidney transplant recipients. In a recent study in adults, POR*28 was associated with increased dosing requirements early after transplant of CYP3A5-expressing kidney transplant recipients. The authors aimed to evaluate the additional contribution of POR*28 to early tacrolimus disposition in pediatric kidney transplant recipients. Methods: Retrospective data of 43 pediatric kidney transplan...
Abstract
Cited 95 times since 2014 (8.3 per year)
source: EuropePMC
Surgical endoscopy,
Volume 28, Issue 4, 1 1 2014, Pages 1076-1082
Optimization of near-infrared fluorescence cholangiography for open and laparoscopic surgery.
Verbeek FP, Schaafsma BE, Tummers QR, van der Vorst JR, van der Made WJ, Baeten CI, Bonsing BA, Frangioni JV, van de Velde CJ, Vahrmeijer AL, Swijnenburg RJ
Background: During laparoscopic cholecystectomy, common bile duct (CBD) injury is a rare but severe complication. To reduce the risk of injury, near-infrared (NIR) fluorescent cholangiography using indocyanine green (ICG) has recently been introduced as a novel method of visualizing the biliary system during surgery. To date, several studies have shown feasibility of this technique; however, liver background fluorescence remains a major problem during fluorescent cholangiography. The aim of the...
Abstract
Cited 13 times since 2014 (1.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 4, 1 1 2014, Pages 186-189
Using genetic variation for establishing causality of cardiovascular risk factors: overcoming confounding and reverse causality.
Smit RA, Trompet S, de Craen AJ, Jukema JW
Cardiovascular disease (CVD) remains the leading cause of death in developed countries, despite the decline of CVD mortality over the last two decades. From observational, predictive research, efforts have been made to find causal risk factors for CVD. However, in recent years, some of these findings have been shown to be mistaken. Possible explanations for the discrepant findings are confounding and reverse causation. Genetic epidemiology has tried to address these problems through the use of M...
Abstract
Cited 221 times since 2014 (19.4 per year)
source: EuropePMC
Cell,
Volume 157, Issue 2, 1 1 2014, Pages 329-339
Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus.
Linster M, van Boheemen S, de Graaf M, Schrauwen EJA, Lexmond P, Mänz B, Bestebroer TM, Baumann J, van Riel D, Rimmelzwaan GF, Osterhaus ADME, Matrosovich M, Fouchier RAM, Herfst S
Recently, A/H5N1 influenza viruses were shown to acquire airborne transmissibility between ferrets upon targeted mutagenesis and virus passage. The critical genetic changes in airborne A/Indonesia/5/05 were not yet identified. Here, five substitutions proved to be sufficient to determine this airborne transmission phenotype. Substitutions in PB1 and PB2 collectively caused enhanced transcription and virus replication. One substitution increased HA thermostability and lowered the pH of membrane f...
Abstract
Cited 36 times since 2014 (3.2 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 4, 1 1 2014, Pages 160-166
Left cardiac sympathetic denervation in the Netherlands for the treatment of inherited arrhythmia syndromes.
Olde Nordkamp LR, Driessen AH, Odero A, Blom NA, Koolbergen DR, Schwartz PJ, Wilde AA
Introduction: Treating therapy-resistant patients with inherited arrhythmia syndromes can be difficult and left cardiac sympathetic denervation (LCSD) might be a viable alternative treatment option. We provide an overview of the indications and outcomes of LCSD in patients with inherited arrhythmia syndromes in the only tertiary referral centre in the Netherlands where LCSD is conducted in these patients. Methods: This was a retrospective study, including all patients with inherited arrhythmia s...
Abstract
Cited 27 times since 2014 (2.4 per year)
source: EuropePMC
Annals of oncology : official journal of the European Society for Medical Oncology,
Volume 25, Issue 6, 31 5 2014, Pages 1198-1203
Screening for coronary artery disease after mediastinal irradiation in Hodgkin lymphoma survivors: phase II study of indication and acceptance†.
Daniëls LA, Krol AD, de Graaf MA, Scholte AJ, Van't Veer MB, Putter H, de Roos A, Schalij MJ, Creutzberg CL
Background: Cardiovascular diseases are the most common nonmalignant cause of death in Hodgkin lymphoma (HL) survivors, especially after mediastinal irradiation. We investigated the role of computed tomographic coronary angiography (CTA) as a screening tool for coronary artery disease (CAD) in asymptomatic HL survivors, and related CTA findings to exercise testing and subsequent interventions. Patients and methods: Patients were eligible for this phase II study if at least 10 years disease-free...
Abstract
