9618 results
Cited 2 times since 2013 (0.2 per year)
source: EuropePMC
Frontiers in psychology,
Volume 4, 26 4 2013, Pages 883
Visual attention for a desktop virtual environment with ambient scent.
Toet A, van Schaik MG
In the current study participants explored a desktop virtual environment (VE) representing a suburban neighborhood with signs of public disorder (neglect, vandalism, and crime), while being exposed to either room air (control group), or subliminal levels of tar (unpleasant; typically associated with burned or waste material) or freshly cut grass (pleasant; typically associated with natural or fresh material) ambient odor. They reported all signs of disorder they noticed during their walk togethe...
Abstract
Cited 12 times since 2013 (1 per year)
source: EuropePMC
Breast cancer research and treatment,
Volume 143, Issue 1, 22 4 2013, Pages 171-179
CYP2D6 genotype in relation to hot flashes as tamoxifen side effect in a Dutch cohort of the tamoxifen exemestane adjuvant multinational (TEAM) trial.
Dezentjé VO, Gelderblom H, Van Schaik RH, Vletter-Bogaartz JM, Van der Straaten T, Wessels JA, Kranenbarg EM, Berns EM, Seynaeve C, Putter H, Van de Velde CJ, Nortier JW, Guchelaar HJ
In tamoxifen-treated breast cancer patients the occurrence of hot flashes may be associated with effective estrogen receptor antagonism dependent on genetic variations of metabolic enzymes and the estrogen receptor. Early breast cancer patients who were randomized to receive tamoxifen, followed by exemestane within the tamoxifen exemestane adjuvant multinational trial were genotyped for five CYP2D6 alleles. CYP2D6 genotypes and phenotypes were related to the occurrence of hot flashes as adverse...
Abstract
Cited 2 times since 2013 (0.2 per year)
source: EuropePMC
Frontiers in neuroscience,
Volume 7, 15 3 2013, Pages 212
The ripple pond: enabling spiking networks to see.
Afshar S, Cohen GK, Wang RM, Van Schaik A, Tapson J, Lehmann T, Hamilton TJ
We present the biologically inspired Ripple Pond Network (RPN), a simply connected spiking neural network which performs a transformation converting two dimensional images to one dimensional temporal patterns (TP) suitable for recognition by temporal coding learning and memory networks. The RPN has been developed as a hardware solution linking previously implemented neuromorphic vision and memory structures such as frameless vision sensors and neuromorphic temporal coding spiking neural networks...
Abstract
Cited 19 times since 2013 (1.6 per year)
source: EuropePMC
Thyroid : official journal of the American Thyroid Association,
Volume 24, Issue 2, 13 2 2013, Pages 208-214
Subclinical thyroid dysfunction and functional capacity among elderly.
Virgini VS, Wijsman LW, Rodondi N, Bauer DC, Kearney PM, Gussekloo J, den Elzen WP, Jukema JW, Westendorp RG, Ford I, Stott DJ, Mooijaart SP, PROSPER Study Group
Background: Subclinical thyroid dysfunction is common among older people and has been associated with decreased functional capacity but with conflicting data. The aim of this study was to assess the association between subclinical thyroid dysfunction and functional capacity in an elderly population. Methods: We included 5182 participants with a mean age of 75.2 years from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Self-reported functional capacity was assessed using t...
Abstract
Cited 47 times since 2013 (4 per year)
source: EuropePMC
General and comparative endocrinology,
Volume 195, 13 2 2013, Pages 151-156
Hair as a long-term retrospective cortisol calendar in orang-utans (Pongo spp.): new perspectives for stress monitoring in captive management and conservation.
Carlitz EH, Kirschbaum C, Stalder T, van Schaik CP
This study examined whether the method of hair cortisol analysis is applicable to orang-utans (Pongo spp.) and can help to advance the objective monitoring of stress in non-human primates. Specifically, we examined whether fundamental prerequisites for hair cortisol analysis are given in orang-utans and, subsequently, whether segmental hair analysis may provide a retrospective calendar of long-term cortisol levels. For this, hair samples were examined from 71 zoo-living orang-utans (38 males, me...
Abstract
Cited 70 times since 2013 (5.9 per year)
source: EuropePMC
PloS one,
Volume 8, Issue 11, 13 2 2013, Pages e80017
Linkage to HIV, TB and non-communicable disease care from a mobile testing unit in Cape Town, South Africa.
Govindasamy D, Kranzer K, van Schaik N, Noubary F, Wood R, Walensky RP, Freedberg KA, Bassett IV, Bekker LG
Background: HIV counseling and testing may serve as an entry point for non-communicable disease screening. Objectives: To determine the yield of newly-diagnosed HIV, tuberculosis (TB) symptoms, diabetes and hypertension, and to assess CD4 count testing, linkage to care as well as correlates of linkage and barriers to care from a mobile testing unit. Methods: A mobile unit provided screening for HIV, TB symptoms, diabetes and hypertension in Cape Town, South Africa between March 2010 and Septembe...
Abstract
Cited 109 times since 2013 (9.3 per year)
source: EuropePMC
The lancet. Diabetes & endocrinology,
Volume 2, Issue 3, 12 2 2013, Pages 210-217
Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study.
Bakker LE, Boon MR, van der Linden RA, Arias-Bouda LP, van Klinken JB, Smit F, Verberne HJ, Jukema JW, Tamsma JT, Havekes LM, van Marken Lichtenbelt WD, Jazet IM, Rensen PC
Background: Individuals of south Asian origin have a very high risk of developing type 2 diabetes compared with white Caucasians. We aimed to assess volume and activity of brown adipose tissue (BAT), which is thought to have a role in energy metabolism by combusting fatty acids and glucose to produce heat and might contribute to the difference in incidence of type 2 diabetes between ethnic groups. Methods: We enrolled Dutch nationals with south Asian ancestry and matched Caucasian participants a...
Abstract
Cited 8 times since 2013 (0.7 per year)
source: EuropePMC
Clinical genitourinary cancer,
Volume 12, Issue 3, 12 2 2013, Pages 190-195
Radical cystectomy in a Dutch University hospital: long-term outcomes and prognostic factors in a homogeneous surgery-only series.
Bruins HM, Arends TJ, Pelkman M, Hulsbergen-van de Kaa CA, van der Heijden AG, Witjes JA
Background: The aim of this study was to present survival outcomes and identify prognostic factors in patients undergoing radical cystectomy (RC) for urothelial bladder cancer (UBC) in a homogeneous surgery-only series. Patients and methods: Patients who underwent RC for UBC with intent-to-cure between January 1998 and December 2010 without neoadjuvant or adjuvant treatment were included in this retrospective study. Clinical and histopathologic data were collected and institutional review board...
Abstract
Cited 50 times since 2013 (4.2 per year)
source: EuropePMC
Psychological research,
Volume 78, Issue 6, 8 2 2013, Pages 878-891
Optimal training design for procedural motor skills: a review and application to laparoscopic surgery.
Spruit EN, Band GP, Hamming JF, Ridderinkhof KR
This literature review covers the choices to consider in training complex procedural, perceptual and motor skills. In particular, we focus on laparoscopic surgery. An overview is provided of important training factors modulating the acquisition, durability, transfer, and efficiency of trained skills. We summarize empirical studies and their theoretical background on the topic of training complex cognitive and motor skills that are pertinent to proficiency in laparoscopic surgery. The overview pe...
Abstract
Cited 4 times since 2013 (0.3 per year)
source: EuropePMC
PloS one,
Volume 8, Issue 11, 8 2 2013, Pages e78721
No effect of ambient odor on the affective appraisal of a desktop virtual environment with signs of disorder.
Toet A, van Schaik M, Theunissen NC
Background: Desktop virtual environments (VEs) are increasingly deployed to study the effects of environmental qualities and interventions on human behavior and safety related concerns in built environments. For these applications it is essential that users appraise the affective qualities of the VE similar to those of its real world counterpart. Previous studies have shown that factors like simulated lighting, sound and dynamic elements all contribute to the affective appraisal of a desktop VE....
Abstract
Cited 21 times since 2013 (1.8 per year)
source: EuropePMC
IEEE transactions on biomedical circuits and systems,
Volume 8, Issue 4, 8 2 2013, Pages 453-464
Asynchronous binaural spatial audition sensor with 2 × 64 × 4 channel output.
Liu SC, van Schaik A, Minch BA, Delbruck T
This paper proposes an integrated event-based binaural silicon cochlea system aimed at efficient spatial audition and auditory scene analysis. The cochlea chip has a matched pair of digitally-calibrated 64-stage cascaded analog second-order filter banks with 512 pulse-frequency modulated (PFM) address-event representation (AER) outputs. The quality factors (Qs) of channels are individually adjusted by local DACs. The 2P4M 0.35 um CMOS chip consumes an average power of 14 mW including its integra...
Abstract
Cited 10 times since 2013 (0.8 per year)
source: EuropePMC
American heart journal,
Volume 167, Issue 2, 6 1 2013, Pages 178-185
Erectile dysfunction in the cardiology practice-a patients' perspective.
Nicolai MP, van Bavel J, Somsen GA, de Grooth GJ, Tulevski II, Lorsheyd A, Putter H, Schalij MJ, Pelger RC, Elzevier HW
Background: Erectile dysfunction (ED) is an independent risk factor for cardiovascular events sharing mutual risk factors with coronary artery disease. Several guidelines for the management of ED in cardiovascular disease have been proposed, recommending cardiologists to routinely inquire about erectile function. However, males' specific needs and wishes regarding sexual health care in cardiology are unknown. We sought to identify male patients' view concerning possible improvements in...
Abstract
Cited 12 times since 2013 (1 per year)
source: EuropePMC
Gene,
Volume 534, Issue 2, 6 1 2013, Pages 197-203
High prevalence of cerebral venous sinus thrombosis (CVST) as presentation of cystathionine beta-synthase deficiency in childhood: molecular and clinical findings of Turkish probands.
Karaca M, Hismi B, Ozgul RK, Karaca S, Yilmaz DY, Coskun T, Sivri HS, Tokatli A, Dursun A
Classical homocystinuria is the most commonly inherited disorder of sulfur metabolism, caused by the genetic alterations in human cystathionine beta-synthase (CBS) gene. In this study, we present comprehensive clinical findings and the genetic basis of homocystinuria in a cohort of Turkish patients. Excluding some CBS mutations, detailed genotype-phenotype correlation for different CBS mutations has not been established in literature. We aimed to make clinical subgroups according to main clinica...
Abstract
Cited 36 times since 2013 (3.1 per year)
source: EuropePMC
Annals of surgery,
Volume 258, Issue 5, 1 1 2013, Pages 743-51; discussion 752-3
The 14q32 microRNA-487b targets the antiapoptotic insulin receptor substrate 1 in hypertension-induced remodeling of the aorta.
Nossent AY, Eskildsen TV, Andersen LB, Bie P, Brønnum H, Schneider M, Andersen DC, Welten SM, Jeppesen PL, Hamming JF, Hansen JL, Quax PH, Sheikh SP
Objectives: To study the role of microRNAs in hypertension-induced vascular pathology before the onset of symptoms of severe cardiovascular disease. Background: MicroRNAs play a crucial role in cardiovascular disease. However, microRNAs are often studied in full-blown cardiovascular disease models, not during development of cardiovascular pathology. Methods: Angiotensin II was infused into healthy adult rats, inducing chronic hypertension, and microRNA expression profiles were obtained. The most...
Abstract
Cited 43 times since 2013 (3.6 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 7, Issue 1, 1 1 2013, Pages 74-81
Association between left ventricular global longitudinal strain and adverse left ventricular dilatation after ST-segment-elevation myocardial infarction.
Joyce E, Hoogslag GE, Leong DP, Debonnaire P, Katsanos S, Boden H, Schalij MJ, Marsan NA, Bax JJ, Delgado V
Background: Myocardial infarct size is a major determinant of left ventricular (LV) remodeling after ST-segment-elevation myocardial infarction. We evaluated whether LV global longitudinal strain (GLS), proposed as a novel marker of infarct size, is associated with 3- and 6-month LV dilatation after ST-segment-elevation myocardial infarction. Methods and results: In the first ST-segment-elevation myocardial infarction patients treated with primary percutaneous coronary intervention, baseline LVG...
Abstract
Cited 40 times since 2013 (3.4 per year)
source: EuropePMC
Emerging infectious diseases,
Volume 19, Issue 11, 1 1 2013, Pages 1797-1802
Transmissibility of livestock-associated methicillin-resistant Staphylococcus aureus.
Hetem DJ, Bootsma MC, Troelstra A, Bonten MJ
Previous findings have suggested that the nosocomial transmission capacity of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is lower than that of other MRSA genotypes. We therefore performed a 6-month (June 1-November 30, 2011) nationwide study to quantify the single-admission reproduction number, RA, for LA-MRSA in 62 hospitals in the Netherlands and to compare this transmission capacity to previous estimates. We used spa typing for genotyping. Quantification of RA...
Abstract
Cited 7 times since 2013 (0.6 per year)
source: EuropePMC
Clinical chemistry and laboratory medicine,
Volume 51, Issue 11, 1 1 2013, Pages 2187-2193
Assessment of plasma aminothiol levels and the association with recurrent atherothrombotic events in patients hospitalized for an acute coronary syndrome: a prospective study.
Focks JJ, van Schaik A, Clappers N, van Dijk EG, van Oijen MG, Verheugt FW, Peters WH
Background: The aminothiols homocysteine and, to a lesser extent, cysteine have been associated with adverse cardiovascular outcome, whereas glutathione, as an antioxidant, may protect against atherosclerosis and thrombosis. Potentially, the combined assessment of these aminothiols may provide a more accurate association with future cardiovascular outcome. We evaluated the association between recurrent atherothrombotic events and the concentration of total plasma cysteine, homocysteine, and glut...
Abstract
Cited 16 times since 2013 (1.4 per year)
source: EuropePMC
Journal of electrocardiology,
Volume 47, Issue 2, 1 1 2013, Pages 175-182
Electrocardiographic detection of right ventricular pressure overload in patients with suspected pulmonary hypertension.
Kamphuis VP, Haeck ML, Wagner GS, Maan AC, Maynard C, Delgado V, Vliegen HW, Swenne CA
Background and purpose: Early, preferably noninvasive, detection of pulmonary hypertension improves prognosis. Our study evaluated the diagnostic accuracy of the electrocardiographically derived Butler-Leggett (BL) score and ventricular gradient (VG) to estimate mean pulmonary artery pressure (PAP). Methods: In 63 patients with suspected pulmonary hypertension, BL score and VG were calculated. The VG was projected on a direction optimized for detection of right ventricular pressure overload (VG-...
Abstract
Cited 14 times since 2013 (1.2 per year)
source: EuropePMC
European journal of anaesthesiology,
Volume 30, Issue 11, 1 1 2013, Pages 685-694
Minimised closed circuit coronary artery bypass grafting in the elderly is associated with lower levels of organ-specific biomarkers: a prospective randomised study.
van Boven WJ, Gerritsen WB, Driessen AH, van Dongen EP, Klautz RJ, Aarts LP
Background: Restrictive fluid management may protect organ function and improve postoperative outcome in elderly coronary artery bypass grafting (CABG) patients. Objective: We assessed organ-specific biomarker release to study the contribution of a fluid restrictive closed circuit concept to organ protection in elderly CABG patients. Cardiac, respiratory and abdominal organ injury was measured during and following minimal fluid coronary artery bypass grafting (mCABG), off-pump coronary artery by...
Abstract
Cited 6 times since 2013 (0.5 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 6, Issue 6, 1 1 2013, Pages 855-857
Papillary muscle infarction, mitral regurgitation, and long-term prognosis.
Bax JJ, Delgado V
Abstract
