Research

Publications

Below you can find a list of our published research.

9618 results

Cited 29 times since 2013 (2.4 per year) source: EuropePMC

International journal of epidemiology, Volume 42, Issue 5, 1 1 2013, Pages 1371-1380 Parental smoking during pregnancy and cardiovascular structures and function in childhood: the Generation R Study. Taal HR, de Jonge LL, van Osch-Gevers L, Steegers EA, Hofman A, Helbing WA, van der Heijden AJ, Jaddoe VW

Background: Foetal smoke exposure might lead to foetal developmental adaptations that permanently affect the cardiovascular system. We assessed the associations of both maternal and paternal smoking during pregnancy with childhood cardiovascular structures and function. Method: In a prospective cohort study among 5565 children, we examined whether maternal and paternal smoking during pregnancy are associated with blood pressure, carotid-femoral pulse wave velocity and left cardiac structures and... Abstract

Cited 10 times since 2013 (0.8 per year) source: EuropePMC

Cardiovascular drugs and therapy, Volume 27, Issue 5, 1 1 2013, Pages 433-439 Long term effects of epoetin alfa in patients with ST- elevation myocardial infarction. Fokkema ML, Kleijn L, van der Meer P, Belonje AM, Achterhof SK, Hillege HL, van 't Hof A, Jukema JW, Peels HO, Henriques JP, ten Berg JM, Vos J, van Gilst WH, van Veldhuisen DJ, Voors AA

Purpose: The HEBE III trial showed that epoetin alfa administration in patients with a first ST-elevation myocardial infarction (STEMI) did not improve left ventricular function at 6 weeks after primary percutaneous coronary intervention (PCI). The long term effects of erythropoiesis- stimulating agents on cardiovascular morbidity and mortality are unknown, therefore we evaluated clinical events at 1 year after PCI. Methods: A total of 529 patients with a first STEMI and successful primary PCI w... Abstract

Cited 4 times since 2013 (0.3 per year) source: EuropePMC

Indian dermatology online journal, Volume 4, Issue 4, 1 1 2013, Pages 369-371 A cases series of Piezogenic pedal papules. Karadag AS, Bilgili SG, Guner S, Yilmaz D

Abstract

Cited 18 times since 2013 (1.5 per year) source: EuropePMC

Journal of African earth sciences (Oxford, England : 1994), Volume 86, 1 1 2013, Pages 65-106 Orogen styles in the East African Orogen: A review of the Neoproterozoic to Cambrian tectonic evolution. Fritz H, Abdelsalam M, Ali KA, Bingen B, Collins AS, Fowler AR, Ghebreab W, Hauzenberger CA, Johnson PR, Kusky TM, Macey P, Muhongo S, Stern RJ, Viola G

The East African Orogen, extending from southern Israel, Sinai and Jordan in the north to Mozambique and Madagascar in the south, is the world́s largest Neoproterozoic to Cambrian orogenic complex. It comprises a collage of individual oceanic domains and continental fragments between the Archean Sahara-Congo-Kalahari Cratons in the west and Neoproterozoic India in the east. Orogen consolidation was achieved during distinct phases of orogeny between ∼850 and 550 Ma. The northern part of the oroge... Abstract

Cited 63 times since 2013 (5.3 per year) source: EuropePMC

Therapeutic drug monitoring, Volume 35, Issue 5, 1 1 2013, Pages 608-616 Impact of CYP3A4*22 allele on tacrolimus pharmacokinetics in early period after renal transplantation: toward updated genotype-based dosage guidelines. Elens L, Capron A, van Schaik RH, De Meyer M, De Pauw L, Eddour DC, Latinne D, Wallemacq P, Mourad M, Haufroid V

Background: Tacrolimus (Tac) metabolism is mainly mediated by the cytochrome P450 3A (CYP3A) subfamily. Recently, it has been reported that kidney transplant recipients carrying the CYP3A4*22 decrease-of-function allele require lower Tac doses and are more at risk of Tac overexposure than CYP3A4*1/*1 patients. This effect was shown to be independent of the CYP3A5*3 allelic status. However, the pharmacokinetic (PK) parameters assessed in previous studies were limited on single time point whole bl... Abstract

Cited 10 times since 2013 (0.8 per year) source: EuropePMC

Current pain and headache reports, Volume 17, Issue 10, 1 1 2013, Pages 365 Fabry disease: a rare cause of neuropathic pain. Biegstraaten M, Linthorst GE, van Schaik IN, Hollak CE

Fabry disease is characterized by burning or shooting pains in hands and feet, which have a severe impact on the quality of life of patients. It is therefore of importance that Fabry patients receive adequate diagnosis, counseling, treatment and follow up. This review describes neuropathic pain in classical Fabry disease with the aim to help clinicians to recognize Fabry patients among patients presenting with chronic extremity pain. The diagnostic dilemmas in patients with neuropathic pain and... Abstract

Cited 32 times since 2013 (2.7 per year) source: EuropePMC

Current opinion in neurology, Volume 26, Issue 5, 1 1 2013, Pages 496-502 Chronic inflammatory demyelinating polyradiculoneuropathy: update on clinical features, phenotypes and treatment options. Eftimov F, van Schaik I

Purpose of review: In this review, we focus on less recognised signs and symptoms in typical chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and on the clinical presentation, course of disease and response to treatment of the atypical CIDP phenotypes. Recent findings: Frequently occurring and often disabling symptoms in CIDP such as fatigue, pain and tremor have recently been emphasised, whereas autonomic dysfunction, if present, is usually mild. Sensory CIDP is probably the mos... Abstract

Cited 7 times since 2013 (0.6 per year) source: EuropePMC

Computational and mathematical methods in medicine, Volume 2013, 30 5 2013, Pages 238937 Comparison of SVM and ANFIS for snore related sounds classification by using the largest Lyapunov exponent and entropy. Ankışhan H, Yılmaz D

Snoring, which may be decisive for many diseases, is an important indicator especially for sleep disorders. In recent years, many studies have been performed on the snore related sounds (SRSs) due to producing useful results for detection of sleep apnea/hypopnea syndrome (SAHS). The first important step of these studies is the detection of snore from SRSs by using different time and frequency domain features. The SRSs have a complex nature that is originated from several physiological and physic... Abstract

Cited 55 times since 2013 (4.6 per year) source: EuropePMC

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Volume 33, Issue 4, 29 5 2013, Pages 479-490 Determinants of virulence of influenza A virus. Schrauwen EJ, de Graaf M, Herfst S, Rimmelzwaan GF, Osterhaus AD, Fouchier RA

Influenza A viruses cause yearly seasonal epidemics and occasional global pandemics in humans. In the last century, four human influenza A virus pandemics have occurred. Occasionally, influenza A viruses that circulate in other species cross the species barrier and infect humans. Virus reassortment (i.e. mixing of gene segments of multiple viruses) and the accumulation of mutations contribute to the emergence of new influenza A virus variants. Fortunately, most of these variants do not have the... Abstract

Cited 30 times since 2013 (2.5 per year) source: EuropePMC

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Volume 25, Issue 3, 27 4 2013, Pages 875-885 The societal costs of femoral neck fracture patients treated with internal fixation. Zielinski SM, Bouwmans CA, Heetveld MJ, Bhandari M, Patka P, Van Lieshout EM, FAITH trial investigators

Summary: The study rationale was to provide a detailed overview of the costs for femoral neck fracture treatment with internal fixation in the Netherlands. Mean total costs per patient at 2-years follow-up were 19,425. Costs were higher for older, less healthy patients. Results are comparable to internationally published costs. Introduction: The aim of this study was to provide a detailed overview of the cost and healthcare consumption of patients treated for a hip fracture with internal fixatio... Abstract

Cited 7 times since 2013 (0.6 per year) source: EuropePMC

Heart and vessels, Volume 29, Issue 5, 27 4 2013, Pages 619-628 Prognostic implications of left ventricular regional function heterogeneity assessed with two-dimensional speckle tracking in patients with ST-segment elevation myocardial infarction and depressed left ventricular ejection fraction. Hoogslag GE, Thijssen J, Höke U, Boden H, Antoni ML, Debonnaire P, Haeck ML, Holman ER, Bax JJ, Ajmone Marsan N, Schalij MJ, Delgado V

The aim of the current study was to evaluate the prognostic implications of myocardial tissue heterogeneity assessed with two-dimensional speckle-tracking echocardiography in patients three months after first ST-segment elevation myocardial infarction (STEMI) with left ventricular ejection fraction (LVEF) ≤35 %. For this purpose, a total of 79 patients with first STEMI and LVEF ≤35 % at three months postinfarction were evaluated. Based on left ventricular (LV) speckle-tracking longitudinal strai... Abstract

Cited 7 times since 2013 (0.6 per year) source: Scopus

Interactive cardiovascular and thoracic surgery, Volume 18, Issue 1, 26 4 2013, Pages 33-37 Primary closure using Redon drains for the treatment of post-sternotomy mediastinitis. Vos RJ, van Putte BP, Sonker U, Kloppenburg GT

Objectives: Post-sternotomy mediastinitis is a severe complication of open heart surgery resulting in prolonged hospital stay and increased mortality. Vacuum-assisted closure is commonly used as treatment for post-sternotomy mediastinitis, but has some disadvantages. Primary closure over high vacuum suction Redon drains previously has shown to be an alternative approach with promising results. We report our short- and long-term results of Redon therapy-treated mediastinitis. Methods: We performe... Abstract

American heart journal, Volume 166, Issue 5, 24 4 2013, Pages e43 Reply to letter to the editor by Koza et al. Kooiman J, le Haen PA, Gezgin G, de Vries JP, Boersma D, Brulez HF, Sijpkens YW, van der Molen AJ, Cannegieter SC, Hamming JF, Huisman MV

Abstract

Cited 30 times since 2013 (2.5 per year) source: EuropePMC

Circulation, Volume 128, Issue 25, 24 4 2013, Pages 2732-2744 Atrium-specific Kir3.x determines inducibility, dynamics, and termination of fibrillation by regulating restitution-driven alternans. Bingen BO, Neshati Z, Askar SF, Kazbanov IV, Ypey DL, Panfilov AV, Schalij MJ, de Vries AA, Pijnappels DA

Background: Atrial fibrillation is the most common cardiac arrhythmia. Ventricular proarrhythmia hinders pharmacological atrial fibrillation treatment. Modulation of atrium-specific Kir3.x channels, which generate a constitutively active current (I(K,ACh-c)) after atrial remodeling, might circumvent this problem. However, it is unknown whether and how I(K,ACh-c) contributes to atrial fibrillation induction, dynamics, and termination. Therefore, we investigated the effects of I(K,ACh-c) blockade... Abstract

Cited 70 times since 2013 (5.9 per year) source: EuropePMC

The American journal of cardiology, Volume 112, Issue 12, 21 3 2013, Pages 1867-1872 Outcome after ST elevation myocardial infarction in patients with cancer treated with primary percutaneous coronary intervention. Velders MA, Boden H, Hofma SH, Osanto S, van der Hoeven BL, Heestermans AA, Cannegieter SC, Jukema JW, Umans VA, Schalij MJ, van Boven AJ

The simultaneous occurrence of cancer and coronary heart disease is increasing in the Western world. Nevertheless, the influence of cancer on ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) has not been investigated extensively. This multicenter registry included patients with STEMI treated with primary PCI from 2006 to 2009. Patients were stratified according to history of cancer, and primary focus lay on all-cause and cardiac mortalities... Abstract

Cited 20 times since 2013 (1.7 per year) source: EuropePMC

PloS one, Volume 8, Issue 9, 19 3 2013, Pages e75573 Erythrocyte-bound apolipoprotein B in relation to atherosclerosis, serum lipids and ABO blood group. Klop B, van de Geijn GJ, Bovenberg SA, van der Meulen N, Elte JW, Birnie E, Njo TL, Janssen HW, van Miltenburg A, Jukema JW, Cabezas MC

Introduction: Erythrocytes carry apolipoprotein B on their membrane, but the determining factors of erythrocyte-bound apolipoprotein B (ery-apoB) are unknown. We aimed to explore the determinants of ery-apoB to gain more insight into potential mechanisms. Methods: Subjects with and without CVD were included (N = 398). Ery-apoB was measured on fresh whole blood samples using flow cytometry. Subjects with ery-apoB levels ≤ 0.20 a.u. were considered deficient. Carotid intima media thickness (CIMT)... Abstract

Cited 65 times since 2013 (5.5 per year) source: EuropePMC

PloS one, Volume 8, Issue 9, 16 3 2013, Pages e74083 BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality. Boon MR, van den Berg SA, van den Berg SA, Wang Y, van den Bossche J, Karkampouna S, Bauwens M, De Saint-Hubert M, van der Horst G, Vukicevic S, de Winther MP, Havekes LM, Jukema JW, Tamsma JT, van der Pluijm G, van Dijk KW, Rensen PC

Background/aims: Brown adipose tissue (BAT) dissipates energy stored in triglycerides as heat via the uncoupling protein UCP-1 and is a promising target to combat hyperlipidemia and obesity. BAT is densely innervated by the sympathetic nervous system, which increases BAT differentiation and activity upon cold exposure. Recently, Bone Morphogenetic Protein 7 (BMP7) was identified as an inducer of BAT differentiation. We aimed to elucidate the role of sympathetic activation in the effect of BMP7 o... Abstract

Cited 12 times since 2013 (1 per year) source: EuropePMC

Journal of surgical education, Volume 71, Issue 2, 14 2 2013, Pages 222-228 Quality of life of surgical oncology residents and fellows across Europe. Mordant P, Deneuve S, Rivera C, Carrabin N, Mieog JS, Malyshev N, Van Der Vorst JR, Audisio RA, French Association of Young Surgical Oncologists (AJCO), European Society of Surgical Oncology Young Surgeons and Alumni Club (EYSAC)

Background: Data are currently lacking regarding the quality of life of surgical oncology (SO) trainees. We sought to assess the training conditions and quality of life of SO residents and fellows across Europe. Material and methods: Members of the European Society for Surgical Oncology were invited to complete a Web-based survey that included a questionnaire specifically designed for SO trainees. Demographics, timing, and incentive to choose for SO, quality of life, and symptoms of fatigue, sle... Abstract

Cited 16 times since 2013 (1.3 per year) source: Scopus

The American journal of cardiology, Volume 112, Issue 11, 13 2 2013, Pages 1800-1806 Multidetector row computed tomography parameters associated with paravalvular regurgitation after transcatheter aortic valve implantation. Katsanos S, Ewe SH, Debonnaire P, van der Kley F, de Weger A, Palmen M, Scholte AJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V

Multidetector row computed tomographic (MDCT) assessment of aortic annulus dimensions and frame position and deployment have been associated with paravalvular aortic regurgitation (PAVR) after transcatheter aortic valve implantation (TAVI). The present evaluation investigated the (pre- and postprocedure) MDCT associates of PAVR ≥2+. In total, 123 patients referred for TAVI underwent clinical evaluation, transthoracic echocardiography, and pre- and post-TAVI MDCT. Pre-TAVI MDCT measurements of th... Abstract

Cited 96 times since 2013 (8 per year) source: EuropePMC

Circulation, Volume 128, Issue 21, 13 2 2013, Pages 2289-2295 Initial human feasibility of infusion needle catheter ablation for refractory ventricular tachycardia. Sapp JL, Beeckler C, Pike R, Parkash R, Gray CJ, Zeppenfeld K, Kuriachan V, Stevenson WG

Background: Ablation of ventricular tachycardia (VT) is sometimes unsuccessful when ablation lesions are of insufficient depth to reach arrhythmogenic substrate. We report the initial experience with the use of a catheter with an extendable/retractable irrigated needle at the tip capable of intramyocardial mapping and ablation. Methods and results: Sequential consenting patients with recurrent VT underwent ablation with the use of a needle-tipped catheter. At target sites, the needle was advance... Abstract