6173 results
Cited 4 times since 1997 (0.1 per year)
source: EuropePMC
Pflugers Archiv : European journal of physiology,
Volume 435, Issue 1, 1 1 1997, Pages 130-136
The effect of sarcoplasmic reticulum blockade on the force/frequency relationship and systolic contraction patterns in the newborn pig heart.
Klautz RJ, Baan J, Teitel DF
We investigated the relationship between heart rate and contractility in seven anaesthetized young piglets by measuring contractility at different atrial pacing rates. To study the origin of this relationship we repeated the measurements after blocking the sarcoplasmic reticulum calcium release channel with ryanodine. We assessed contractility using indices derived from instantaneous left ventricular pressure and volume measured by micromanometric and conductance catheters during rapid inferior...
Abstract
Cited 38 times since 1997 (1.4 per year)
source: EuropePMC
Circulation,
Volume 96, Issue 9, 1 1 1997, Pages 2978-2986
Left ventricular pressure-volume relationships before and after cardiomyoplasty in patients with heart failure.
Schreuder JJ, van der Veen FH, van der Velde ET, Delahaye F, Alfieri O, Jegaden O, Lorusso R, Jansen JR, Hoeksel SA, Finet G, Volterrani M, Kaulbach HG, Baan J, Wellens HJ
Background: The aim of this study was to elucidate whether beneficial effects of cardiomyoplasty (CMP) in patients with dilated cardiomyopathy are the result of a decrease in existing ventricular dilatation or a prevention of further dilatation. Methods and results: Combined micromanometer-conductance catheters were used to evaluate left ventricular pressure-volume relationships in six patients with dilated cardiomyopathy before and at 6 and 12 months after CMP. Acute changes in preload and afte...
Abstract
Cited 37 times since 1997 (1.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 30, Issue 6, 1 1 1997, Pages 1491-1499
Modulation of lipoprotein(a) atherogenicity by high density lipoprotein cholesterol levels in middle-aged men with symptomatic coronary artery disease and normal to moderately elevated serum cholesterol. Regression Growth Evaluation Statin Study (REGRESS) Study Group.
Cobbaert C, Jukema JW, Zwinderman AH, Withagen AJ, Lindemans J, Bruschke AV
Objectives: This study sought to examine whether lipoprotein(a) levels predict coronary artery lumen changes in patients with symptomatic coronary artery disease (CAD) and normal to moderate hypercholesterolemia. Background: Recent conflicting reports have confirmed or refuted the association of lipoprotein(a) with clinical events or angiographically verified disease progression. Methods: The association between serum lipoprotein(a) and changes in coronary artery lumen was studied in 704 men ent...
Abstract
Cited 93 times since 1997 (3.4 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 17, Issue 11, 1 1 1997, Pages 2837-2842
Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients.
Jansen H, Verhoeven AJ, Weeks L, Kastelein JJ, Halley DJ, van den Ouweland A, Jukema JW, Seidell JC, Birkenhäger JC
We studied the molecular basis of low hepatic lipase (HL) activity in normolipidemic male patients with angiographically documented coronary artery disease (CAD). In 18 subjects with a lowered HL activity (< 225 mU/mL), all nine exons of the HL gene and part of the promoter region (nucleotides -524 to +7) were sequenced. No structural mutations in the coding part of the HL gene were found, but 50% of the subjects showed a C-to-T substitution at nucleotide -480. Screening for the base substitu...
Abstract
Cited 13 times since 1997 (0.5 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 114, Issue 5, 1 1 1997, Pages 844-846
Switch back: using the pulmonary autograft to replace the aortic valve after arterial switch operation.
Hazekamp MG, Schoof PH, Suys BE, Hutter PA, Meijboom EJ, Ottenkamp J, Huysmans HA
Abstract
Cited 18 times since 1997 (0.7 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 17, Issue 10, 1 1 1997, Pages 2177-2187
Involvement of calcium and G proteins in the acute release of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells.
van den Eijnden-Schrauwen Y, Atsma DE, Lupu F, de Vries RE, Kooistra T, Emeis JJ
In this study, we investigated the role of Ca2+ and G proteins in thrombin-induced acute release (regulated secretion) of tissue-type plasminogen activator (TPA) and von Willebrand factor (vWF), using a previously described system of primary human umbilical vein endothelial cells (HUVECs). The acute release of TPA and vWF, as induced by alpha-thrombin, was almost zero after chelation of Ca2+i, showing that an increase in [Ca2+]i was required. It did not matter whether the increase in [Ca2+]i cam...
Abstract
Cited 106 times since 1997 (3.8 per year)
source: EuropePMC
Circulation,
Volume 96, Issue 8, 1 1 1997, Pages 2573-2577
Thermolabile methylenetetrahydrofolate reductase in coronary artery disease.
Kluijtmans LA, Kastelein JJ, Lindemans J, Boers GH, Heil SG, Bruschke AV, Jukema JW, van den Heuvel LP, Trijbels FJ, Boerma GJ, Verheugt FW, Willems F, Blom HJ
Background: Hyperhomocysteinemia, an independent and graded risk factor for coronary artery disease (CAD), may result from both environmental and hereditary factors. Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of methylenetetrahydrofolate to methyltetrahydrofolate, the methyl donor in the remethylation of homocysteine to methionine. A 677C-->T mutation in the MTHFR gene has been associated with elevated homocysteine concentrations in homozygous (+/+) individuals. Meth...
Abstract
Cited 6 times since 1997 (0.2 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 114, Issue 4, 1 1 1997, Pages 560-567
Acute elevation of coronary venous pressure does not affect left ventricular contractility in the normal and stressed swine heart: implications for the Fontan operation.
Klautz RJ, van Rijk-Zwikker GL, Steendijk P, Wilde J, Teitel DF, Baan J
Objective: After the Fontan operation the right atrium and, thus, the coronary sinus are connected to the pulmonary arterial system, which causes the coronary venous pressure to increase. We investigated the acute effects of elevation of coronary venous pressure on baseline hemodynamics, coronary venous flow, and left ventricular contractility. Methods: In acutely instrumented pigs, during complete right heart bypass and during constant cardiac output, pressure in the right atrium, right ventric...
Abstract
Cited 11 times since 1997 (0.4 per year)
source: EuropePMC
AJR. American journal of roentgenology,
Volume 169, Issue 4, 1 1 1997, Pages 995-999
Biventricular function in patients with nonischemic right ventricle tachyarrhythmias assessed with MR imaging.
Kayser HW, Schalij MJ, van der Wall EE, Stoel BC, de Roos A
Abstract
Cited 2 times since 1997 (0.1 per year)
source: EuropePMC
The Journal of pathology,
Volume 183, Issue 1, 1 1 1997, Pages 99-104
Identification of host and donor cells in porcine homograft heart valve explants by fluorescence in situ hybridization.
Braun J, Hazekamp MG, Koolbergen DR, Sugihara H, Goffin YA, Huysmans HA, Cornelisse CJ
The pathogenesis of the primary tissue degeneration that limits the life-span of aortic and pulmonary homografts has still not been revealed. Histopathological studies on homograft explants have not given definitive insight into the eventual fate of donor cells, nor have they demonstrated the assumed importance of host cell ingrowth into the graft tissue. In this experimental study, fluorescence in situ hybridization (FISH) is introduced as a new approach to examine the distribution of host and...
Abstract
Investigative radiology,
Volume 32, Issue 9, 1 1 1997, Pages 540-549
Quantitative assessment of the presence of a single leg separation in Björk-Shiley convexoconcave prosthetic heart valves.
Vrooman HA, Maliepaard C, van der Linden LP, Jessurun ER, Ludwig JW, Plokker HW, Schalij MJ, Weeda HW, Laufer JL, Huysmans HA, Reiber JH
Rationale and objectives: The authors developed an analytic software package for the objective and reproducible assessment of a single leg separation (SLS) in the outlet strut of Björk-Shiley convexoconcave (BSCC) prosthetic heart valves. Methods: The radiographic cinefilm recordings of 18 phantom valves (12 intact and 6 SLS) and of 43 patient valves were acquired. After digitization of regions of interest in a cineframe, several processing steps were carried out to obtain a one-dimensional corr...
Abstract
Cited 31 times since 1997 (1.1 per year)
source: EuropePMC
European heart journal,
Volume 18, Issue 9, 1 1 1997, Pages 1505-1513
Comparison of echocardiography with magnetic resonance imaging in the assessment of the athlete's heart.
Pluim BM, Beyerbacht HP, Chin JC, Zwinderman A, Van der Laarse A, De Roos A, Vliegen HW, Van der Wall EE
Aim: The purpose of the study was to compare the accuracy of M-mode echocardiography and two different two-dimensional echocardiographic approaches in the assessment of left ventricular mass and volumes in endurance-trained and strength-trained athletes, using magnetic resonance imaging as reference standard. Methods and results: We studied 19 athletes and 10 untrained control subjects, M-mode and two-dimensional echocardiography were compared to magnetic resonance imaging. M-mode echocardiograp...
Abstract
Cited 6 times since 1997 (0.2 per year)
source: EuropePMC
Circulation,
Volume 96, Issue 3, 1 1 1997, Pages 1025-1030
Hemodynamic effects of chronic prenatal ventricular pacing for the treatment of complete atrioventricular block.
Liddicoat JR, Klein JR, Reddy VM, Klautz RJ, Teitel DF, Hanley FL
Background: Increasing the heart rate of the fetus with cardiac failure caused by complete AV block (CAVB) may allow delivery of a full-term, stable neonate with preserved ventricular function. Direct fetal pacing may be a feasible method to achieve this, but the effect of pacing on the structure and function of the rapidly developing fetal heart is unknown. Methods and results: CAVB was created in fetal lambs at 80% gestation by cryoablating the AV node. Epicardial ventricular pacing at 130 bpm...
Abstract
Cited 37 times since 1997 (1.3 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 64, Issue 2, 1 1 1997, Pages 521-525
Modified ultrafiltration after cardiopulmonary bypass in pediatric cardiac surgery.
Draaisma AM, Hazekamp MG, Frank M, Anes N, Schoof PH, Huysmans HA
Background: Cardiopulmonary bypass in children results in considerable water retention, especially in neonates and small infants. Dilution of plasma proteins increases water loss into the extravascular compartments. Excessive total body water may prolong ventilatory support and may contribute to a prolongation of intensive care convalescence. After discontinuation of cardiopulmonary bypass, modified ultrafiltration can be used to withdraw plasma water from the total circulating volume. Methods:...
Abstract
Cited 27 times since 1997 (1 per year)
source: EuropePMC
The Prostate,
Volume 32, Issue 3, 1 1 1997, Pages 196-204
Plasminogen activator and matrix metalloproteinase production and extracellular matrix degradation by rat prostate cancer cells in vitro: correlation with metastatic behavior in vivo.
Quax PH, de Bart AC, Schalken JA, Verheijen JH
Background: The plasminogen activation (PA) and metalloproteinase (MMP) system are involved in tumor cell migration and invasion. Methods: The proteolytic activity of cell lines originating from the rat Dunning R-3327 prostate tumor was analyzed by measuring in vitro extracellular matrix degradation, enzyme activity, and mRNA levels of enzymes, inhibitors, and receptors, and compared with their known metastatic behavior in vivo. Results: Only the highly metastatic sublines AT-3, MATLu, and MATLy...
Abstract
Cited 33 times since 1997 (1.2 per year)
source: EuropePMC
Thrombosis and haemostasis,
Volume 78, Issue 2, 1 1 1997, Pages 880-886
The migration of human smooth muscle cells in vitro is mediated by plasminogen activation and can be inhibited by alpha2-macroglobulin receptor associated protein.
Wijnberg MJ, Quax PH, Nieuwenbroek NM, Verheijen JH
The plasminogen activation system is thought to be important in cell migration processes. A role for this system during smooth muscle cell migration after vascular injury has been suggested from several animal studies. However, not much is known about its involvement in human vascular remodelling. We studied the involvement of the plasminogen activation system in human smooth muscle cell migration in more detail using an in vitro wound assay and a matrix invasion assay. Inhibition of plasmin act...
Abstract
Cited 5 times since 1997 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 18, Issue 8, 1 1 1997, Pages 1313-1321
Beneficial effect of enalapril on left ventricular remodelling in patients with a severe residual stenosis after acute anterior wall infarction.
Baur LH, Schipperheyn JJ, van der Wall EE, van der Velde EA, Schalij MJ, van Eck-Smit BL, van der Laarse A, Voogd PJ, Sedney MI, Reiber JH, Bruschke AV
Objective: The present study was designed to evaluate the effects of early angiotensin converting enzyme (ACE) inhibition on left ventricular enlargement in patients with anterior wall infarction following reperfusion therapy. Methods: Seventy-one consecutive patients with an anterior wall myocardial infarction were randomly allocated to enalapril (n = 36) or placebo (n = 35). All patients received either thrombolytic therapy (n = 46) or underwent primary coronary angioplasty (n = 25). Medicatio...
Abstract
Cited 9 times since 1997 (0.3 per year)
source: EuropePMC
European journal of pediatrics,
Volume 156, Issue 7, 1 1 1997, Pages 516-520
The value of MRI in diagnosing vascular abnormalities causing stridor.
Beekman RP, Beek FJ, Hazekamp MG, Meijboom EJ
Unlabelled: In a 2 year period seven patients who presented with stridor, without respiratory compromise, and three patients without obstructive symptoms were prospectively selected, and underwent MRI. In eight patients with a vascular ring and a pulmonary sling, MRI delineated the vascular abnormality and normal great vessels were found in two patients. Conclusion: MRI successfully delineates the great vessels and demonstrates the presence of a vascular ring and pulmonary sling.
Abstract
Cited 15 times since 1997 (0.5 per year)
source: EuropePMC
Biochemical and biophysical research communications,
Volume 236, Issue 3, 1 1 1997, Pages 544-548
Autosomal recessive liver phosphorylase kinase deficiency caused by a novel splice-site mutation in the gene encoding the liver gamma subunit (PHKG2).
van Beurden EA, de Graaf M, Wendel U, Gitzelmann R, Berger R, van den Berg IE
To facilitate mutation analysis of patients with an autosomal recessive form of liver phosphorylase kinase deficiency, the genomic structure of the gene encoding the testis/liver gamma subunit (PHKG2) was established. The gene consist of 10 exons. The translation start site is located in exon 2. Analysis of DNA from two female siblings, affected with liver phosphorylase kinase deficiency, by exon specific amplification followed by direct sequencing, revealed a single donor splice site mutation i...
Abstract
Cited 25 times since 1997 (0.9 per year)
source: EuropePMC
Circulation,
Volume 96, Issue 2, 1 1 1997, Pages 429-435
Functional evaluation of lipid-lowering therapy by pravastatin in the Regression Growth Evaluation Statin Study (REGRESS)
Aengevaeren WR, Uijen GJ, Jukema JW, Bruschke AV, van der Werf T
Background: Lipid-lowering therapy during 2 years in the Regression Growth Evaluation Statin Study (REGRESS) was associated with less progression of coronary atherosclerosis in the pravastatin group compared with the placebo group. The effect of lipid-lowering therapy on the functional state of the coronary circulation is less well known. The purpose of this study was to evaluate this effect. Methods and results: In a substudy of REGRESS, 69 patients were randomized to pravastatin or placebo. Th...
Abstract
