6173 results
Cited 2 times since 2004 (0.1 per year)
source: EuropePMC
Physiological measurement,
Volume 25, Issue 2, 1 1 2004, Pages 565-576
Assessment of parallel conductance for the trans-cardiac conductance method: can we use the hypertonic saline method with pulmonary artery injections?
Staal EM, Baan J, Jukema JW, van der Wall EE, Steendijk P
The trans-cardiac conductance (TCC) method provides on-line left ventricular (LV) volume signals by determining the electrical conductance of blood in the LV using central venous and epithoracic electrodes. Conductive structures outside the LV cause a 'parallel conductance' offset term (Vp) that is determined by bolus injections of hypertonic saline in the pulmonary artery (Vp(saline)). Analysis of the increased conductance signal during passage of the bolus through the LV yields Vp(sa...
Abstract
Cited 16 times since 2004 (0.8 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 39, Issue 4, 1 1 2004, Pages 850-858
Ingrowth of aorta wall into stent grafts impregnated with basic fibroblast growth factor: a porcine in vivo study of blood vessel prosthesis healing.
van der Bas JM, Quax PH, van den Berg AC, Visser MJ, van der Linden E, van Bockel JH
Objective: Endovascular aneurysm repair is an alternative treatment of abdominal aortic aneurysm. The procedure is less invasive, and morbidity and most probably mortality are reduced. However, some problems, such as endoleakage, are yet to be resolved. Endoleakage can occur after graft migration, as a result of insufficient fixation of the stent graft. One cause is deficient healing between the aortic neck and the stent graft. We hypothesize that better healing, achieved by induction of vascula...
Abstract
Cited 19 times since 2004 (0.9 per year)
source: EuropePMC
Virology,
Volume 321, Issue 2, 1 1 2004, Pages 287-296
Stable transduction of large DNA by high-capacity adeno-associated virus/adenovirus hybrid vectors.
Gonçalves MA, van der Velde I, Knaän-Shanzer S, Valerio D, de Vries AA
Viral vectors with high cloning capacity and host chromosomal integration ability are in demand for the efficient and permanent genetic modification of target cells with large DNA molecules. We have generated a hybrid gene transfer vehicle consisting of recombinant adeno-associated virus (AAV) replicative intermediates packaged in adenovirus (Ad) capsids. This arrangement allows cell cycle-independent nuclear delivery of recombinant AAV genomes with lengths considerably above the maximum size (i...
Abstract
Cited 9 times since 2004 (0.4 per year)
source: EuropePMC
Human gene therapy,
Volume 15, Issue 3, 1 1 2004, Pages 229-238
Pronounced antitumor efficacy by extracellular activation of a doxorubicin-glucuronide prodrug after adenoviral vector-mediated expression of a human antibody-enzyme fusion protein.
de Graaf M, Pinedo HM, Oosterhoff D, van der Meulen-Muileman IH, Gerritsen WR, Haisma HJ, Boven E
Tumor-specific activation of the glucuronide prodrug of doxorubicin, N-[4-doxorubicin-N-carbonyl(oxymethyl)phenyl]-O-beta-glucuronyl carbamate (DOX-GA3), by beta-glucuronidase present in necrotic tumor areas might be improved after transduction of tumor cells to secrete a targeted form of beta-glucuronidase. To that end, we constructed an adenovirus vector, designated Ad/C28-GUSh, encoding human beta-glucuronidase fused to a human single-chain Fv (scFv) against the epithelial cell adhesion molec...
Abstract
Cited 122 times since 2004 (5.8 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 27, Issue 3, 1 1 2004, Pages 308-313
QRS duration and shortening to predict clinical response to cardiac resynchronization therapy in patients with end-stage heart failure.
Molhoek SG, VAN Erven L, Bootsma M, Steendijk P, Van Der Wall EE, Schalij MJ
Despite current selection criteria (NYHA Class III-IV, LVEF < 35%, QRS > 120 ms with LBBB), 30% of patients do not benefit from cardiac resynchronization therapy (CRT). The use of QRS duration as selection criteria for CRT has not been evaluated systematically yet. Accordingly, the value of QRS duration at baseline (and reduction in QRS duration after CRT) to predict responders was studied. Patients were evaluated at baseline and after 6 months of CRT for NYHA Class, quality of life score,...
Abstract
Cited 47 times since 2004 (2.2 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 43, Issue 5, 1 1 2004, Pages 854-857
The cholesteryl ester transfer protein (CETP) TaqIB polymorphism in the cholesterol and recurrent events study: no interaction with the response to pravastatin therapy and no effects on cardiovascular outcome: a prospective analysis of the CETP TaqIB polymorphism on cardiovascular outcome and interaction with cholesterol-lowering therapy.
de Grooth GJ, Zerba KE, Huang SP, Tsuchihashi Z, Kirchgessner T, Belder R, Vishnupad P, Hu B, Klerkx AH, Zwinderman AH, Jukema JW, Sacks FM, Kastelein JJ, Kuivenhoven JA
Objectives: On the basis of quantitative coronary angiography data, the cholesteryl ester transfer protein (CETP) TaqIB gene polymorphism has been postulated to predict the progression of coronary atherosclerosis and response to cholesterol-lowering therapy. Background: Cholesteryl ester transfer protein mediates the exchange of lipids between anti-atherogenic high-density lipoprotein (HDL) and atherogenic apolipoprotein B containing lipoproteins and therefore plays a key role in human lipid met...
Abstract
Cited 6 times since 2004 (0.3 per year)
source: EuropePMC
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
Volume 22, Issue 6, 1 1 2004, Pages 1153-1156
Case 2. Intracardiac metastasis from a Merkel cell carcinoma.
Jongbloed MR, Kanen BL, Visser M, Niessen H, Flens MJ, Loffeld RJ
Abstract
Cited 43 times since 2004 (2 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 77, Issue 3, 1 1 2004, Pages 794-9; discussion 799
Long-term follow-up of coronary artery bypass grafting in three-vessel disease using exclusively pedicled bilateral internal thoracic and right gastroepiploic arteries.
Tavilla G, Kappetein AP, Braun J, Gopie J, Tjien AT, Dion RA
Background: Considerable data now exist that show that coronary artery bypass grafting with bilateral internal thoracic artery (ITA) grafts produce better outcomes than the use of a single ITA graft. The benefit of a third arterial graft has been less well established. Therefore this article describes the survival and cardiac-related event-free survival in patients having bilateral ITA and gastroepiploic artery (GEA) grafting for 3-vessel disease. Methods: From November 1992 to May 2002, 201 pat...
Abstract
Cited 5 times since 2004 (0.2 per year)
source: EuropePMC
Journal of pediatric hematology/oncology,
Volume 26, Issue 3, 1 1 2004, Pages 154-155
Propionic acidemia with myelodysplasia and neutropenia in a Turkish child.
Sipahi T, Yilmaz D, Tavil B
Abstract
Cited 34 times since 2004 (1.6 per year)
source: EuropePMC
Journal of hypertension,
Volume 22, Issue 3, 1 1 2004, Pages 501-509
Relation between exercise-induced hypertension and sustained hypertension in adult patients after successful repair of aortic coarctation.
Vriend JW, van Montfrans GA, Romkes HH, Vliegen HW, Veen G, Tijssen JG, Mulder BJ
Objectives: To investigate whether exercise-induced hypertension in successfully repaired adult post-coarctectomy patients is associated with hypertension on 24-h blood pressure measurement and increased left ventricular mass. Methods: One hundred and forty-four consecutive post-coarctectomy patients (mean age 31.5 years, range 17-74 years; mean age at repair 7.9 years, range 0-45 years) from three tertiary referral centres were studied using ambulatory blood pressure monitoring, treadmill exerc...
Abstract
Cited 4 times since 2004 (0.2 per year)
source: EuropePMC
European journal of heart failure,
Volume 6, Issue 2, 1 1 2004, Pages 187-193
QT dispersion correlates to myocardial viability assessed by dobutamine stress echocardiography in patients with severely depressed left ventricular function due to coronary artery disease.
Bountioukos M, Schinkel AF, Poldermans D, Rizzello V, Vourvouri EC, Krenning BJ, Biagini E, Roelandt JR, Bax JJ
Background: QT dispersion is prolonged in numerous cardiac diseases, representing a general repolarization abnormality. Aim: To evaluate the influence of viable myocardium on QT dispersion in patients with severely depressed left ventricular (LV) function due to coronary artery disease. Methods and results: 103 patients with ischemic cardiomyopathy (LV ejection fraction [EF]: 25+/-6%) were studied. Patients underwent 12-lead electrocardiography to assess QT dispersion, and two-dimensional echoca...
Abstract
Cited 71 times since 2004 (3.4 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 43, Issue 6, 1 1 2004, Pages 1027-1033
The effects of cardiac resynchronization therapy on left ventricular function, myocardial energetics, and metabolic reserve in patients with dilated cardiomyopathy and heart failure.
Sundell J, Engblom E, Koistinen J, Ylitalo A, Naum A, Stolen KQ, Kalliokoski R, Nekolla SG, Airaksinen KE, Bax JJ, Knuuti J
Objectives: The effects of long-term cardiac resynchronization therapy (CRT) on left ventricular (LV) energetics and metabolic reserve were evaluated. Background: Cardiac resynchronization therapy is a new therapy for patients with drug-refractory severe heart failure (HF). Methods: Ten patients with idiopathic dilated cardiomyopathy who had undergone implantation of biventricular pacemaker 8 +/- 5 months earlier were studied during two conditions: CRT switched on, and after CRT was switched off...
Abstract
Cited 229 times since 2004 (10.8 per year)
source: EuropePMC
Journal of clinical microbiology,
Volume 42, Issue 3, 1 1 2004, Pages 981-986
Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages.
Maertzdorf J, Wang CK, Brown JB, Quinto JD, Chu M, de Graaf M, van den Hoogen BG, Spaete R, Osterhaus AD, Fouchier RA
The discovery of human metapneumovirus and its implications for respiratory tract disease have emphasized the need for a sensitive, specific, and rapid assay to detect this virus in a clinical setting. It recently became clear that human metapneumovirus can be grouped into at least four genetic lineages. Previously described assays for the detection of human metapneumovirus were developed by using limited sequence information and failed to detect viruses from all four genetic lineages with compa...
Abstract
Cited 83 times since 2004 (3.9 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 15, Issue 3, 1 1 2004, Pages 349-355
Embryonic conduction tissue: a spatial correlation with adult arrhythmogenic areas.
Jongbloed MR, Schalij MJ, Poelmann RE, Blom NA, Fekkes ML, Wang Z, Fishman GI, Gittenberger-De Groot AC
Introduction: The occurrence of arrhythmias in adult patients may arise preferentially in anatomic regions derived from the specialized cardiac conduction system. To examine this hypothesis, we performed a detailed analysis of the developing cardiac conduction system using the recently described CCS-lacZ transgenic mouse strain. Methods and results: Transgenic embryos (E9.5-15.5) were stained for beta-galactosidase activity and co-stained with the myocardial marker HHF35. Results were reconstruc...
Abstract
Cited 298 times since 2004 (14 per year)
source: EuropePMC
Arthritis research & therapy,
Volume 6, Issue 2, 5 1 2004, Pages R142-50
Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin.
Vossenaar ER, Després N, Lapointe E, van der Heijden A, Lora M, Senshu T, van Venrooij WJ, Ménard HA
Antibodies directed to the Sa antigen are highly specific for rheumatoid arthritis (RA) and can be detected in approximately 40% of RA sera. The antigen, a doublet of protein bands of about 50 kDa, is present in placenta and in RA synovial tissue. Although it has been stated that the Sa antigen is citrullinated vimentin, experimental proof for this claim has never been published. In this study, we investigated the precise nature of the antigen. Peptide sequences that were obtained from highly pu...
Abstract
Cited 5 times since 2004 (0.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 20, Issue 1, 1 1 2004, Pages 53-60
Six-months of recombinant human GH therapy in patients with ischemic cardiac failure.
van Thiel SW, Smit JW, de Roos A, Bax JJ, van der Wall EE, Biermasz NR, Viergever E, Vliegen HW, Romijn JA, Roelfsema F, Lamb HJ
Growth hormone therapy in patients with idiopathic dilated cardiomyopathy and ischemic cardiac failure has revealed varying effects on systolic function, probably related to the response in serum insulin-like growth factor I (IGF-I) levels. As diastolic function has not been studied thoroughly, we studied the effects of 6 months of recombinant human growth hormone (rh GH) treatment on systolic and diastolic function in patients with ischemic cardiac failure, using cardiovascular magnetic resonan...
Abstract
Cited 3 times since 2004 (0.1 per year)
source: EuropePMC
Circulation,
Volume 109, Issue 4, 1 1 2004, Pages e25-6
Images in cardiovascular medicine. Dynamic multislice computed tomography of left ventricular function.
Dirksen MS, Bax JJ, de Roos A, Jukema JW, van der Geest RJ, Geleijns J, van der Wall EE, Lamb HJ
Abstract
Cited 1 times since 2004 (0 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 77, Issue 2, 1 1 2004, Pages 725
Elective surgery for fibroelastoma of the aortic valve.
Koolbergen DR, Voigt P, Kolowca M, Smit VT, Somer ST, Dion RA
Abstract
Cited 28 times since 2004 (1.3 per year)
source: EuropePMC
Expert opinion on pharmacotherapy,
Volume 5, Issue 2, 1 1 2004, Pages 459-468
Amlodipine and atorvastatin in atherosclerosis: a review of the potential of combination therapy.
Jukema JW, van der Hoorn JW
Hypertension and hyperlipidaemia are major risk factors for the development of atherosclerosis. Calcium channel blockers (CCBs) have been used for decades and have established antihypertensive effects. Statins have been extensively used because of their potent lipid lowering properties. Amongst other factors, inflammation and oxidation are involved in enhanced progression of atherosclerosis and new lesion development. Therefore, research has been initiated focusing on the antioxidant and anti-in...
Abstract
Cited 5 times since 2004 (0.2 per year)
source: EuropePMC
Clinical science (London, England : 1979),
Volume 106, Issue 2, 1 1 2004, Pages 173-181
Dobutamine induces ineffective work in regional ischaemic myocardium: an experimental strain rate imaging study.
Weidemann F, Broscheit J, Eberbach N, Steendijk P, Voelker W, Greim C, Ertl G, Roewer N, Strotmann JM
In the present study, we sought to investigate the effects of differing inotropic conditions on regional myocardial function in ischaemic segments. In an experimental pig model ( n =11), the regional deformation parameters peak systolic strain rate [SR(SYS) (peak velocity of thickening)], systolic strain [epsilon(SYS) (systolic wall thickening)] and post-systolic strain [epsilon(PST) (ongoing wall thickening after end of systole)] were measured during normal perfusion and regional ischaemia of t...
Abstract
