7959 results
Cited 12 times since 2022 (5 per year)
source: EuropePMC
European journal of human genetics : EJHG,
Volume 31, Issue 12, 12 2 2022, Pages 1364-1370
Dutch pharmacogenetics working group (DPWG) guideline for the gene-drug interaction of CYP2D6 and COMT with atomoxetine and methylphenidate.
Nijenhuis M, Soree B, Jama WOM, de Boer-Veger NJ, Buunk AM, Guchelaar HJ, Houwink EJF, Rongen GA, van Schaik RHN, Swen JJ, Touw D, van der Weide J, van Westrhenen R, Deneer VHM, Risselada A
Pharmacogenetics (PGx) studies the effect of heritable genetic variation on drug response. Clinical adoption of PGx has remained limited, despite progress in the field. To promote implementation, the Dutch Pharmacogenetics Working Group (DPWG) develops evidence-based guidelines on how to optimize pharmacotherapy based on PGx test results. This guideline describes optimization of atomoxetine therapy based on genetic variation in the CYP2D6 gene. The CYP2D6 enzyme is involved in conversion of atom...
Abstract
Cited 18 times since 2022 (7.4 per year)
source: EuropePMC
The American journal of medicine,
Volume 136, Issue 3, 10 2 2022, Pages 260-269.e7
Integrating Coronary Atherosclerosis Burden and Progression with Coronary Artery Disease Risk Factors to Guide Therapeutic Decision Making.
Freeman AM, Raman SV, Aggarwal M, Maron DJ, Bhatt DL, Parwani P, Osborne J, Earls JP, Min JK, Bax JJ, Shapiro MD
Importance: Although atherosclerosis represents the primary driver of coronary artery disease, evaluation and treatment approaches have historically relied upon indirect markers of atherosclerosis that include surrogates (cholesterol), signs (angina), and sequelae (ischemia) of atherosclerosis. Direct quantification and characterization of atherosclerosis may encourage a precision heart care paradigm that improves diagnosis, risk stratification, therapeutic decision-making, and longitudinal dise...
Abstract
Cited 4 times since 2022 (1.6 per year)
source: EuropePMC
Journal of magnetic resonance imaging : JMRI,
Volume 57, Issue 5, 9 2 2022, Pages 1320-1339
Particle Tracing Based on 4D Flow Magnetic Resonance Imaging: A Systematic Review into Methods, Applications, and Current Developments.
Roos PR, Rijnberg FM, Westenberg JJM, Lamb HJ
Background: Particle tracing based on 4D Flow MRI has been applied as a quantitative and qualitative postprocessing technique to study temporally evolving blood flow patterns. Purpose: To systematically review the various methods to perform 4D Flow MRI-based particle tracing, as well as the clinical value, clinical applications, and current developments of the technique. Study type: The study type is systematic review. Subjects: Patients with cardiovascular disease (such as Marfan, Fontan, Tetra...
Abstract
Cited 14 times since 2022 (5.8 per year)
source: EuropePMC
Environmental research,
Volume 218, 8 2 2022, Pages 114961
The spatial distribution of microplastics in topsoils of an urban environment - Coimbra city case-study.
Leitão IA, van Schaik L, Ferreira AJD, Alexandre N, Geissen V
Due to their seemingly ubiquitous nature and links to environmental and human health problems, microplastics are quickly becoming a major concern worldwide. Artificial environments, such as those found in urban environments, represent some of the main sources of microplastic. However, very few studies have focused on the occurrence of microplastics in urban soils. The aim of the current research was to evaluate the microplastic contamination in urban soils from artificial and natural land uses t...
Abstract
Cited 8 times since 2022 (3.3 per year)
source: EuropePMC
European journal of pediatrics,
Volume 182, Issue 2, 7 1 2022, Pages 757-767
Long-term neurocognitive functioning of children treated with propranolol or atenolol for infantile hemangioma.
Hermans MM, Rietman AB, Schappin R, de Laat PCJ, Mendels EJ, Breur JMPJ, Langeveld HR, de Wildt SN, Breugem CC, de Graaf M, Raphael MF, Pasmans SGMA
The purpose of this study was to compare long-term neurocognitive functioning (working memory, processing speed, and attention) between children who had been treated with either propranolol or atenolol for infantile hemangioma during infancy. All eligible children (n = 158) aged 6 years or older and treated with propranolol or atenolol as infants were invited to participate in this two-center cross-sectional study. The primary outcome was the Wechsler Intelligence Scale for Children-V Cognitive...
Abstract
Cited 5 times since 2022 (2.1 per year)
source: EuropePMC
JTCVS open,
Volume 13, 6 1 2022, Pages 54-74
Early and late effects of aortic root enlargement: Results from the Pericardial Surgical Aortic Valve Replacement Pivotal Trial: A multicenter, prospective clinical trial.
Rao V, Linick JA, Reardon MJ, Vriesendorp MD, Ruel M, Patel HJ, Liu F, Klautz RJM
Objective: During surgical aortic valve replacement, prosthesis-patient mismatch is avoided by implanting the largest possible valve, which sometimes requires annular enlargement (ARE). The effects of ARE on mortality remain controversial. We reviewed data from a multinational clinical trial evaluating a novel pericardial bioprosthesis to determine the influence of ARE 5 years postimplant. Methods: Patients with aortic valve disease requiring surgical aortic valve replacement were prospectively...
Abstract
Frontiers in cardiovascular medicine,
Volume 9, 6 1 2022, Pages 1053100
Editorial: Atherosclerosis and functional imaging.
Huang JY, Lin YH, Hung CL, Chen WP, Tamaki N, Bax JJ, Morris DA, Korosoglou G, Wu YW
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 30, Issue 1, 6 1 2022, Pages 10-13
Third decade of the Journal of Nuclear Cardiology: reflections of an author, reviewer, and editor.
Bax JJ
Abstract
Cited 1 times since 2022 (0.4 per year)
source: EuropePMC
Frontiers in pharmacology,
Volume 13, 5 1 2022, Pages 1032995
Effects of CYP3A4*22 and CYP3A5 on clinical outcome in patients treated with ticagrelor for ST-segment elevation myocardial infarction: POPular Genetics sub-study.
Azzahhafi J, Bergmeijer TO, van den Broek WWA, Chan Pin Yin DRPP, Rayhi S, Peper J, Bor WL, Claassens DMF, van Schaik RHN, Ten Berg JM
Aims: To determine the clinical efficacy, adverse events and side-effect dyspnea of CYP3A4*22 and CYP3A5 expressor status in ticagrelor treated patients. Methods and results: Ticagrelor treated patients from the POPular Genetics randomized controlled trial were genotyped for CYP3A4*22 and CYP3A5*3 alleles. Patients were divided based on their genotype. In total 1,281 patients with ST-segment elevation myocardial infarction (STEMI) were included. CYP3A4*22 carriers (n = 152) versus CYP3A4*22 non-...
Abstract
Cited 3 times since 2022 (1.2 per year)
source: EuropePMC
Journal of scleroderma and related disorders,
Volume 8, Issue 1, 5 1 2022, Pages 64-71
Mouth opening in systemic sclerosis: Its course over time, determinants and impact on mouth handicap.
Khidir SJH, Boonstra M, Bergstra SA, Boerrigter GWM, Voogt-van der Harst EM, Ninaber MK, Ajmone Marsan N, Huizinga TWJ, van der Helm-van Mil AHM, de Vries-Bouwstra JK
Objective: Decreased maximal mouth opening is a common and disabling manifestation in systemic sclerosis patients. We aimed to study the course of maximal mouth opening, determinants of smaller maximal mouth opening over time and the burden of smaller maximal mouth opening on mouth handicap. Methods: Consecutive systemic sclerosis patients participating in the prospective Leiden Combined Care in systemic sclerosis cohort were included. Annual clinical assessment included maximal mouth opening me...
Abstract
Cited 10 times since 2022 (4.1 per year)
source: EuropePMC
Clinical chemistry and laboratory medicine,
Volume 61, Issue 3, 5 1 2022, Pages 442-451
Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy.
van Zundert SKM, Griffioen PH, van Rossem L, Willemsen SP, de Rijke YB, van Schaik RHN, Steegers-Theunissen RPM, Mirzaian M
Objectives: In this study we describe the development and validation of a liquid chromatography mass spectrometry method (LC-MS/MS) to quantify five tryptophan (TRP) metabolites within the kynurenine- and serotonin pathway and apply the method to serum samples of women in the first trimester of pregnancy. A secondary aim was to investigate the correlation between body mass index (BMI) and the five analytes. Methods: A LC-MS/MS was developed for the analysis of TRP, kynurenine (KYN), 5-hydroxytry...
Abstract
Cited 3 times since 2022 (1.2 per year)
source: EuropePMC
Cancers,
Volume 14, Issue 23, 5 1 2022, Pages 5994
Association of Pretreatment Physical and Geriatric Parameters with Treatment Tolerance and Survival in Elderly Patients with Stage I-II Non-Small Cell Lung Cancer: An Evaluation of Usual Care Data.
Voorn MJJ, Bootsma MFR, Bootsma GP, van Kampen-van den Boogaart VEM, van Riet GJA, de Ruysscher DK, Bongers BC, Janssen-Heijnen MLG
In this study, the association of pretreatment physical and geriatric parameters with treatment tolerance and survival in elderly patients with stage I−II NSCLC was evaluated. Retrospective data for patients aged ≥70 years, diagnosed between 2016 and 2020 with stage I−II NSCLC, and who underwent surgery or stereotactic ablative radiotherapy (SABR) in a large Dutch teaching hospital were retrieved from medical records. Associations of pretreatment physical and geriatric parameters with treatment...
Abstract
Cited 23 times since 2022 (9.4 per year)
source: EuropePMC
Allergy,
Volume 78, Issue 3, 3 1 2022, Pages 875-878
Dupilumab has a profound effect on specific-IgE levels of several food allergens in atopic dermatitis patients.
Spekhorst LS, van der Rijst LP, de Graaf M, van Megen M, Zuithoff NPA, Knulst AC, de Bruin-Weller MS, Le TM
Abstract
European heart journal. Cardiovascular Imaging,
Volume 24, Issue 1, 1 1 2022, Pages 36-37
Coronary artery calcium scoring in the general population.
van der Bijl P, Kuneman J, Bax JJ
Abstract
Cited 4 times since 2022 (1.6 per year)
source: EuropePMC
Nature,
Volume 612, Issue 7938, 1 1 2022, Pages E7
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.
Mishra A, Malik R, Hachiya T, Jürgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, Yang C, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Børte S, Cain A, Ridker PM, Cho K, Chen Z, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P, Launer LJ, Lee KJ, Lepik K, Li J, Li L, Manichaikul A, Markus HS, Marston NA, Meitinger T, Mitchell BD, Montellano FA, Morisaki T, Mosley TH, Nalls MA, Nordestgaard BG, O'Donnell MJ, Okada Y, Onland-M
Abstract
Cited 3 times since 2022 (1.2 per year)
source: EuropePMC
Medical education online,
Volume 27, Issue 1, 1 1 2022, Pages 2016561
Publishing your scholarship: a survey of pearls from top reviewers.
Jauregui J, Artino AR, Ilgen JS, Sullivan G, van Schaik SM
Experts have described ways to improve peer review quality. Perspectives from expert reviewers are largely absent in the health professions education literature. To gather guidance from expert reviewers, to aid authors striving to publish and reviewers aiming to perform their task effectively. This study surveyed the Journal of Graduate Medical Education (JGME) 'Top Reviewers' from 2017, 2018, and 2019. 'Top Reviewers' perform four or more reviews per year, with high average...
Abstract
Journal of clinical medicine,
Volume 11, Issue 23, 1 1 2022, Pages 7147
The Predictive Power of the 14-51 Ng/L High Sensitive Troponin T (hsTnT) Values for Predicting Cardiac Revascularization in a Clinical Setting.
De Jongh FW, Pouwels S, De Jongh MC, Dubois EA, van Schaik RHN
Background: high sensitive Troponin T (hsTnT) values between 14−50 ng/L represent a challenge in diagnosing acute coronary syndrome (ACS) at the Emergency Department (ED). The European Society for Cardiology (ESC) recommends a second hsTnT measurement 3 h later to distinguish between ACS and other causes depending on the Δ hsTnT. Our study aims to evaluate the predictive power this approach in a clinical setting by following patients presenting at the ED with hsTnT values 14−51 ng/L. Materials a...
Abstract
Cited 12 times since 2022 (4.9 per year)
source: EuropePMC
Omega,
Volume 91, Issue 2, 1 1 2022, Pages 851-884
The Effect of the COVID-19 Pandemic on Grief Experiences of Bereaved Relatives: An Overview Review.
van Schaik T, Brouwer MA, Knibbe NE, Knibbe HJJ, Teunissen SCCM
The COVID-19 pandemic has disrupted grief experiences of bereaved relatives and altered accustomed ways of coping with loss. To understand how bereaved relatives experienced grief during COVID-19, a review, using the overview method, was conducted. An overview of empirical data about this subject has been lacking and therefore, PubMed and CINAHL databases were searched for empirical studies published from January 1, 2020 until December 31, 2021. 28 articles were included in the review. Thematic...
Abstract
Cited 11 times since 2022 (4.5 per year)
source: EuropePMC
Rheumatology (Oxford, England),
Volume 62, Issue 1, 1 1 2022, Pages 300-309
Ultrasound and MR muscle imaging in new onset idiopathic inflammatory myopathies at diagnosis and after treatment: a comparative pilot study.
Walter AW, Lim J, Raaphorst J, Smithuis FF, den Harder JM, Eftimov F, Potters W, Saris CGJ, de Visser M, van Schaik IN, de Haan RJ, van der Kooi AJ, Verhamme C
Objectives: To prospectively compare ultrasound (US) and whole-body MRI for detection of muscle abnormalities compatible with idiopathic inflammatory myopathies (IIM). Methods: Newly diagnosed IIM patients underwent US (14 muscles) and MRI (36 muscles) at diagnosis and after nine weeks monotherapy with intravenous immunoglobulin. Muscles were compatible with IIM when quantitative US echo-intensity (EI) z scores was ≥1.5, semi-quantitative US Heckmatt score was ≥2, qualitative US was abnormal, or...
Abstract
Cardiovascular research,
Volume 118, Issue 15, 1 1 2022, Pages e105-e107
Conditional immortalization of human cardiomyocytes for translational in vitro modelling of cardiovascular disease.
Harlaar N, Pijnappels DA, de Vries AAF
Abstract
