6125 results
Cited 8 times since 2022 (2.6 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 3 1 2022, Pages 784980
Interfering in the ALK1 Pathway Results in Macrophage-Driven Outward Remodeling of Murine Vein Grafts.
de Jong A, Sier VQ, Peters HAB, Schilder NKM, Jukema JW, Goumans MJTH, Quax PHA, de Vries MR
Aims: Vein grafts are frequently used to bypass coronary artery occlusions. Unfortunately, vein graft disease (VGD) causes impaired patency rates. ALK1 mediates signaling by TGF-β via TGFβR2 or BMP9/10 via BMPR2, which is an important pathway in fibrotic, inflammatory, and angiogenic processes in vascular diseases. The role of the TGF-β pathway in VGD is previously reported, however, the contribution of ALK1 signaling is not known. Therefore, we investigated ALK1 signaling in VGD in a mouse mode...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 29, Issue 1, 1 1 2022, Pages 4
Correction to: The Role of Editors.
Iskandrian AE, Bax JJ
Abstract
Cited 13 times since 2022 (4.2 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 3, 1 1 2022, Pages 412-422
The Leiden Convention coronary coding system: translation from the surgical to the universal view.
Koppel CJ, Vliegen HW, Bökenkamp R, Ten Harkel ADJ, Kiès P, Egorova AD, Jukema JW, Hazekamp MG, Schalij MJ, Gittenberger-de Groot AC, Jongbloed MRM
Aims: The Leiden Convention coronary coding system structures the large variety of coronary anatomical patterns; isolated and in congenital heart disease. It is widely used by surgeons but not by cardiologists as the system uses a surgeons' cranial view. Since thoracic surgeons and cardiologists work closely together, a coronary coding system practical for both disciplines is mandatory. To this purpose, the 'surgical' coronary coding system was adapted to an 'imaging' sy...
Abstract
Cited 2 times since 2022 (0.7 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 16, Issue 4, 1 1 2022, Pages 319-326
Coronary volume to left ventricular mass ratio in patients with diabetes mellitus.
Kuneman JH, El Mahdiui M, van Rosendael AR, van den Hoogen IJ, Patel MR, Nørgaard BL, Fairbairn TA, Nieman K, Akasaka T, Berman DS, Hurwitz Koweek LM, Pontone G, Kawasaki T, Rønnow Sand NP, Jensen JM, Amano T, Poon M, Øvrehus KA, Sonck J, Rabbat MG, De Bruyne B, Rogers C, Matsuo H, Bax JJ, Leipsic JA, Knuuti J
Background: Diabetes mellitus is a major risk factor for coronary artery disease (CAD) and may provoke structural and functional changes in coronary vasculature. The coronary volume to left ventricular mass (V/M) ratio is a new anatomical parameter capable of revealing a potential physiological imbalance between coronary vasculature and myocardial mass. The aim of this study was to examine the V/M derived from coronary computed tomography angiography (CCTA) in patients with diabetes. Methods: Pa...
Abstract
Journal of tissue viability,
Volume 31, Issue 2, 1 1 2022, Pages 358-364
Translation and validation of the ELPO for Turkish population: Risk assessment scale for the development of pressure injuries due to surgical positioning.
Sengul T, Gul A, Yilmaz D, Gokduman T
Aim of the study: This study was conducted to translate the ELPO risk assessment scale for the development of pressure injuries due to surgical positioning to Turkish and to test its validity and reliability in the Turkish Population. Materials and methods: The data were collected using the patient identification form, the risk assessment scale for the prevention of injuries due to surgical positioning, and the Braden Scale. This scale consisted of a total of seven items, each of which contained...
Abstract
Acta clinica Croatica,
Volume 60, Issue 3, 1 1 2022, Pages 361-366
SYNTHETIC CANNABINOID BONZAI RELATED CREATINE KINASE ENZYME ELEVATION: A TURKISH CENTER STUDY.
Erismis B, Yilmaz D, Polat O, Deniz H, Yucel MH, Hursitoglu M
Synthetic cannabinoid (locally named 'Bonzai' in Turkey) use is increasing worldwide (especially among people with low income). One of its harmful adverse effects is an increase in serum levels of muscle enzymes (i.e., creatine kinase [CK]). The aim of this study was to determine the prevalence of Bonzai use in patients admitted with elevated CK levels and to compare the 1-month survival status of Bonzai users with that of non-Bonzai users. This retrospective study was conducted on a t...
Abstract
Pediatric emergency care,
Volume 38, Issue 2, 1 1 2022, Pages e871-e875
Evaluation of Pediatric Maxillofacial Injury: Who Is Critical?
Ulusoy E, Armağan C, Çağlar A, Er A, Akgül F, Çitlenbik H, Yilmaz D, Duman M
Objective: Isolated facial injuries are less common among pediatric trauma patients. The literature has focused on, especially, fractures in facial injuries. There is a limited number of studies evaluating all facial injuries in childhood. The study aims to evaluate the clinical characteristics of maxillofacial injuries and to identify patients who require further intervention. Methods: The data from pediatric patients with maxillofacial injury (
Abstract
Cited 18 times since 2022 (5.9 per year)
source: EuropePMC
JAMA cardiology,
Volume 7, Issue 2, 1 1 2022, Pages 175-183
Outcomes Associated With Catheter Ablation of Ventricular Tachycardia in Patients With Cardiac Sarcoidosis.
Siontis KC, Santangeli P, Muser D, Marchlinski FE, Zeppenfeld K, Hoogendoorn JC, Narasimhan C, Sauer WH, Zipse MM, Kapa S, Vedantham V, Rosenthal DG, Robinson MR, Patton KK, Murgatroyd F, Chicos AB, Soejima K, Roukoz H, Sacher F, Bhan A, Appelbaum J, Dickfeld T, Mankad P, Ellenbogen KA, Kron J, Kim HM, Froehlich J, Eagle KA, Bogun FM, Crawford TC
Importance: Ventricular tachycardia (VT) is associated with high mortality in patients with cardiac sarcoidosis (CS), and medical management of CS-associated VT is limited by high failure rates. The role of catheter ablation has been investigated in small, single-center studies. Objective: To investigate outcomes associated with VT ablation in patients with CS. Design, setting, and participants: This cohort study from the Cardiac Sarcoidosis Consortium registry (2003-2019) included 16 tertiary r...
Abstract
Cited 8 times since 2022 (2.6 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 24, Issue 2, 1 1 2022, Pages 296-305
Comparing clinical performance of current implantable cardioverter-defibrillator implantation recommendations in arrhythmogenic right ventricular cardiomyopathy.
Bosman LP, Bosman LP, Nielsen Gerlach CL, Cadrin-Tourigny J, Orgeron G, Tichnell C, Murray B, Bourfiss M, van der Heijden JF, Yap SC, Zeppenfeld K, van den Berg MP, Wilde AAM, Asselbergs FW, Tandri H, Calkins H, van Tintelen JP, James CA, Te Riele ASJM
Aims: Arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have an increased risk of ventricular arrhythmias (VA). Four implantable cardioverter-defibrillator (ICD) recommendation algorithms are available The International Task Force Consensus ('ITFC'), an ITFC modification by Orgeron et al. ('mITFC'), the AHA/HRS/ACC guideline for VA management ('AHA'), and the HRS expert consensus statement ('HRS'). This study aims to validate and compare the...
Abstract
Cited 4 times since 2022 (1.3 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 8, Issue 4, 31 5 2022, Pages 437-449
Multielectrode Unipolar Voltage Mapping and Electrogram Morphology to Identify Post-Infarct Scar Geometry: Validation by Histology.
Glashan CA, Tofig BJ, Beukers H, Tao Q, Blom SA, Villadsen PR, Lassen TR, de Riva M, Kristiansen SB, Zeppenfeld K
Objectives: This study sought to evaluate the ability of uni- and bipolar electrograms collected with a multielectrode catheter with smaller electrodes to: 1) delineate scar; and 2) determine local scar complexity. Background: Early reperfusion results in variable endocardial scar, often overlaid with surviving viable myocardium. Although bipolar voltage (BV) mapping is considered the pillar of substrate-based ablation, the role of unipolar voltage (UV) mapping has not been sufficiently explored...
Abstract
Frontiers in cardiovascular medicine,
Volume 9, 31 5 2022, Pages 793972
Hybrid CMR- and FDG-PET-Imaging Gives New Insights Into the Relationship of Myocardial Metabolic Activity and Fibrosis in Patients With Becker Muscular Dystrophy.
Vehof V, Büther F, Florian A, Drakos S, Chamling B, Kies P, Stegger L, Yilmaz A
Background: Cardiac involvement in patients with Becker muscular dystrophy (BMD) is an important predictor of mortality. The cardiac phenotype of BMD patients is characterized by slowly progressive myocardial fibrosis that starts in the left ventricular (LV) free wall segments and extends into the septal wall during the disease course. Purpose: Since the reason for this characteristic cardiac phenotype is unknown and comprehensive approaches using e.g. hybrid imaging combining cardiovascular mag...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Scientific reports,
Volume 12, Issue 1, 31 5 2022, Pages 1628
Chemotherapy response prediction with diffuser elapser network.
Koyuncu B, Melek A, Yilmaz D, Tuzer M, Unlu MB
In solid tumors, elevated fluid pressure and inadequate blood perfusion resulting from unbalanced angiogenesis are the prominent reasons for the ineffective drug delivery inside tumors. To normalize the heterogeneous and tortuous tumor vessel structure, antiangiogenic treatment is an effective approach. Additionally, the combined therapy of antiangiogenic agents and chemotherapy drugs has shown promising effects on enhanced drug delivery. However, the need to find the appropriate scheduling and...
Abstract
Cited 5 times since 2022 (1.6 per year)
source: EuropePMC
BMC health services research,
Volume 22, Issue 1, 30 5 2022, Pages 129
Clarifying responsibility: professional digital health in the doctor-patient relationship, recommendations for physicians based on a multi-stakeholder dialogue in the Netherlands.
Silven AV, van Peet PG, Boers SN, Tabak M, de Groot A, Hendriks D, van Os HJA, Bonten TN, Atsma DE, de Graaf TJ, Sombroek MP, Chavannes NH, Villalobos-Quesada M
Background: Implementation of digital health (eHealth) generally involves adapting pre-established and carefully considered processes or routines, and still raises multiple ethical and legal dilemmas. This study aimed to identify challenges regarding responsibility and liability when prescribing digital health in clinical practice. This was part of an overarching project aiming to explore the most pressing ethical and legal obstacles regarding the implementation and adoption of digital health in...
Abstract
Cited 6 times since 2022 (1.9 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 15, Issue 2, 28 4 2022, Pages e009979
Nonsustained Ventricular Tachycardia Is Independently Associated With Sustained Ventricular Arrhythmias in Nonischemic Dilated Cardiomyopathy.
Piers SR, Androulakis AF, Yim KS, van Rein N, Venlet J, Kapel GF, Siebelink HM, Lamb HJ, Cannegieter SC, Man SC, Zeppenfeld K
Background: Spontaneous nonsustained ventricular tachycardia (NSVT) on Holter, VT inducibility during electrophysiology study, and late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) have been associated with sustained ventricular arrhythmias (SVAs) in nonischemic dilated cardiomyopathy (DCM). This study aimed to analyze whether these parameters carry independent prognostic value for spontaneous SVA in DCM. Methods: Between 2011 and 2018, patients with the DCM clinical spectrum...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 9, Issue 2, 27 4 2022, Pages 43
Sarcomere Disassembly and Transfection Efficiency in Proliferating Human iPSC-Derived Cardiomyocytes.
Yuan Q, Maas RGC, Brouwer ECJ, Pei J, Blok CS, Popovic MA, Paauw NJ, Bovenschen N, Hjortnaes J, Harakalova M, Doevendans PA, Sluijter JPG, van der Velden J, Buikema JW
Contractility of the adult heart relates to the architectural degree of sarcomeres in individual cardiomyocytes (CMs) and appears to be inversely correlated with the ability to regenerate. In this study we utilized multiple imaging techniques to follow the sequence of sarcomere disassembly during mitosis resulting in cellular or nuclear division in a source of proliferating human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). We observed that both mono- and binuclear hiPSC-CMs give ri...
Abstract
Cited 12 times since 2022 (3.9 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 35, Issue 7, 26 4 2022, Pages 703-711.e3
Noninvasive Left Ventricular Myocardial Work in Patients with Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction.
Meucci MC, Butcher SC, Galloo X, van der Velde ET, Marsan NA, Bax JJ, Delgado V
Background: Left ventricular (LV) global longitudinal strain (GLS) has been proposed as a sensitive marker of myocardial damage in patients with chronic severe aortic regurgitation (AR) and preserved LV ejection fraction (LVEF). However, LV GLS does not take into account the afterload. Noninvasive LV myocardial work is a novel parameter of LV myocardial performance, which integrates measurements of myocardial deformation and noninvasive blood pressure (afterload). The aims of this study were (1)...
Abstract
The American journal of cardiology,
Volume 169, 23 4 2022, Pages 93-99
Long-Term Impact of Preventive Tricuspid Valve Annuloplasty on Right Ventricular Remodeling.
Dietz MF, van Wijngaarden AL, Mack MJ, Braun J, Ajmone Marsan N, Delgado V, Klautz R, Bax JJ
In patients with primary mitral regurgitation (MR), concomitant tricuspid valve (TV) annuloplasty at the time of left-sided valve surgery is indicated in case of a dilated TV annulus ≥40 mm independent of the presence or severity of tricuspid regurgitation (TR). However, the long-term impact on right ventricular (RV) adverse remodeling is less well established and the benefit of preventive TV annuloplasty remains controversial. The aim of the study was to assess differences in long-term RV adver...
Abstract
Cited 7 times since 2022 (2.3 per year)
source: EuropePMC
ESC heart failure,
Volume 9, Issue 2, 22 4 2022, Pages 912-924
Functional classification of left ventricular remodelling: prognostic relevance in myocardial infarction.
Chimed S, van der Bijl P, Lustosa R, Fortuni F, Montero-Cabezas JM, Ajmone Marsan N, Gersh BJ, Delgado V, Bax JJ
Aims: The current definition of post ST-segment elevation myocardial infarction (STEMI) left ventricular (LV) remodelling is purely structural (LV dilatation) and does not consider LV function (ejection fraction, EF), even though it is known to be a predictor of long-term post-STEMI outcome. This study aimed to reclassify LV remodelling after STEMI by integrating LV dilatation and function (LVEF) and to investigate the prognostic implications. Methods and results: Data from an ongoing registry o...
Abstract
Cited 16 times since 2022 (5.2 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 35, Issue 5, 21 3 2022, Pages 477-485.e3
Left Atrial Reservoir Function and Outcomes in Secondary Mitral Regurgitation.
Stassen J, Namazi F, van der Bijl P, van Wijngaarden SE, Kamperidis V, Marsan NA, Delgado V, Bax JJ
Background: Left atrial (LA) size is a marker of disease severity and is related to worse outcomes in secondary mitral regurgitation (MR). The prognostic value of LA function assessed by LA reservoir strain (LARS), however, remains unknown. The aim of this study was to investigate the prognostic implications of LARS in patients with significant secondary MR. Methods: LARS was evaluated using speckle-tracking echocardiography in patients with more than mild (grade ≥ 2) secondary MR. The populatio...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Life (Basel, Switzerland),
Volume 12, Issue 2, 21 3 2022, Pages 154
Near-Infrared Fluorescence with Indocyanine Green to Assess Bone Perfusion: A Systematic Review.
Michi M, Madu M, Winters HAH, de Bruin DM, van der Vorst JR, Driessen C
Background: Adequate perfusion of a bone flap is essential for successful reconstruction of osseous defects. Unfortunately, complications related to inadequate bone perfusion are common. Near-infrared fluorescence (NIRF) imaging enables intraoperative visualization of perfusion. NIRF has been investigated in reconstructive surgery to aid the surgeon in clinical perioperative assessment of soft tissue perfusion. However, little is known on the beneficial use of NIRF to assess bone perfusion. Ther...
Abstract
