7429 results
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
International journal of cardiology. Heart & vasculature,
Volume 36, 20 3 2021, Pages 100858
Referral and participation in cardiac rehabilitation of patients following acute coronary syndrome; lessons learned.
Rodrigo SF, Van Exel HJ, Van Keulen N, Van Winden L, Beeres SLMA, Schalij MJ
Purpose: Cardiac rehabilitation (CR) after hospitalization for acute coronary syndrome (ACS) has shown to reduce mortality, readmissions, and improve quality of life. CR is recommended by international guidelines but previous studies have shown low participation rates. Systematic CR referral might improve CR participation. Methods: The present study evaluates CR referral and CR participation of patients hospitalized for ACS in 2017 and treated according to local protocol, which includes systemat...
Abstract
Cited 13 times since 2021 (3.7 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 12, 18 3 2021, Pages 2429-2440
Association of Tube Voltage With Plaque Composition on Coronary CT Angiography: Results From PARADIGM Registry.
Takagi H, Leipsic JA, Indraratna P, Gulsin G, Khasanova E, Tzimas G, Lin FY, Shaw LJ, Lee SE, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Conte E, Marques H, de Araújo Gonçalves P, Gottlieb I, Hadamitzky M, Maffei E, Pontone G, Shin S, Kim YJ, Lee BK, Chun EJ, Sung JM, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Bax JJ, Chang HJ
Objectives: This study sought to investigate the impact of low tube voltage scanning heterogeneity of coronary luminal attenuation on plaque quantification and characterization with coronary computed tomography angiography (CCTA). Background: The impact of low tube voltage and coronary luminal attenuation on quantitative coronary plaque remains uncertain. Methods: A total of 1,236 consecutive patients (age: 60 ± 9 years; 41% female) who underwent serial CCTA at an interval of ≥2 years were inclu...
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 22, Issue 16, 18 3 2021, Pages 8909
In Vivo Matrigel Plug Assay as a Potent Method to Investigate Specific Individual Contribution of Angiogenesis to Blood Flow Recovery in Mice.
Aref Z, Quax PHA
Neovascularization restores blood flow recovery after ischemia in peripheral arterial disease. The main two components of neovascularization are angiogenesis and arteriogenesis. Both of these processes contribute to functional improvements of blood flow after occlusion. However, discriminating between the specific contribution of each process is difficult. A frequently used model for investigating neovascularization is the murine hind limb ischemia model (HLI). With this model, it is difficult t...
Abstract
Cited 5 times since 2021 (1.4 per year)
source: EuropePMC
Frontiers in veterinary science,
Volume 8, 18 3 2021, Pages 670419
Control and Eradication Programs for Six Cattle Diseases in the Netherlands.
Santman-Berends IMGA, Mars MH, Weber MF, van Duijn L, Waldeck HWF, Biesheuvel MM, van den Brink KMJA, Dijkstra T, Hodnik JJ, Strain SAJ, de Roo A, Veldhuis AMB, van Schaik G
Within the European Union, infectious cattle diseases are categorized in the Animal Health Law. No strict EU regulations exist for control, evidence of disease freedom, and surveillance of diseases listed other than categories A and B. Consequently, EU member states follow their own varying strategies for disease control. The aim of this study was to provide an overview of the control and eradication programs (CPs) for six cattle diseases in the Netherlands between 2009 and 2019 and to highlight...
Abstract
Cited 9 times since 2021 (2.5 per year)
source: EuropePMC
Therapeutic advances in medical oncology,
Volume 13, 18 3 2021, Pages 17588359211033704
Circulating <i>TP53</i> mutations are associated with early tumor progression and poor survival in pancreatic cancer patients treated with FOLFIRINOX.
van der Sijde F, Azmani Z, Besselink MG, Bonsing BA, de Groot JWB, Groot Koerkamp B, Haberkorn BCM, Homs MYV, van IJcken WFJ, Janssen QP, Lolkema MP, Luelmo SAC, Mekenkamp LJM, Mustafa DAM, van Schaik RHN, Wilmink JW, Vietsch EE, van Eijck CHJ
Background: Biomarkers predicting treatment response may be used to stratify pancreatic ductal adenocarcinoma (PDAC) patients for therapy. The aim of this study was to identify circulating tumor DNA (ctDNA) mutations that associate with tumor progression during FOLFIRINOX chemotherapy, and overall survival (OS). Methods: Circulating cell-free DNA was analyzed with a 57 gene next-generation sequencing panel using plasma samples of 48 PDAC patients of all disease stages. Patients received FOLFIRIN...
Abstract
Cited 4 times since 2021 (1.1 per year)
source: EuropePMC
Frontiers in immunology,
Volume 12, 18 3 2021, Pages 676662
Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies.
Loeven MA, Maciej-Hulme ML, Yanginlar C, Hubers MC, Kellenbach E, de Graaf M, van Kuppevelt TH, Wetzels J, Rabelink TJ, Smith RJH, van der Vlag J
Complement dysregulation is characteristic of the renal diseases atypical hemolytic uremic syndrome (aHUS) and complement component 3 glomerulopathy (C3G). Complement regulatory protein Factor H (FH) inhibits complement activity, whereas FH-related proteins (FHRs) lack a complement regulatory domain. FH and FHRs compete for binding to host cell glycans, in particular heparan sulfates (HS). HS is a glycosaminoglycan with an immense structural variability, where distinct sulfation patterns mediate...
Abstract
European heart journal. Case reports,
Volume 5, Issue 9, 17 3 2021, Pages ytab335
Fusion cardiac resynchronization therapy in an left ventricular assist device patient from two devices and crossing leads: a case report.
Egorova AD, van Erven L, Beeres SLMA, Tops LF
Background: Cardiac implanted electronic devices (CIED) have significantly improved the survival and quality of life in heart failure patients. Although implantable cardioverter-defibrillators (ICD) and cardiac resynchronization therapy (CRT) have a major role in patients with moderate to severe heart failure symptoms, the role of these devices in patients with a left ventricular assist device (LVAD) is not yet well defined. The burden of CIED-related procedures in patients with an LVAD is high....
Abstract
Cited 11 times since 2021 (3.1 per year)
source: EuropePMC
Thrombosis research,
Volume 206, 17 3 2021, Pages 66-75
Efficacy and safety of a 12-week outpatient pulmonary rehabilitation program in Post-PE Syndrome.
Boon GJAM, Janssen SMJ, Barco S, Bogaard HJ, Ghanima W, Kroft LJM, Meijboom LJ, Ninaber MK, Nossent EJ, Spruit MA, Symersky P, Vliegen HW, Noordegraaf AV, Huisman MV, Siegerink B, Abbink JJ, Klok FA
Background: The Post-Pulmonary Embolism Syndrome (PPES) comprises heterogeneous entities, including chronic thromboembolic disease with/without pulmonary hypertension (CTEPH/CTEPD), and deconditioning. Objectives: To assess underlying physiological determinants of PPES, and efficacy and safety of rehabilitation training in these patients. Methods: 56 consecutive PE patients with persistent dyspnea and/or functional limitations despite ≥3 months of anticoagulation underwent standardized diagnosti...
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 14, Issue 8, 16 3 2021, Pages e009808
Lesion Size and Lesion Maturation After Radiofrequency Catheter Ablation for Ventricular Tachycardia in Humans With Nonischemic Cardiomyopathy.
Glashan CA, Stevenson W, Zeppenfeld K
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
Cells,
Volume 10, Issue 8, 12 2 2021, Pages 2064
Generation, Characterization, and Application of Inducible Proliferative Adult Human Epicardium-Derived Cells.
Ge Y, Smits AM, Liu J, Zhang J, van Brakel TJ, Goumans MJTH, Jongbloed MRM, de Vries AAF
Rationale: In recent decades, the great potential of human epicardium-derived cells (EPDCs) as an endogenous cell source for cardiac regeneration has been recognized. The limited availability and low proliferation capacity of primary human EPDCs and phenotypic differences between EPDCs obtained from different individuals hampers their reproducible use for experimental studies. Aim: To generate and characterize inducible proliferative adult human EPDCs for use in fundamental and applied research....
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
PloS one,
Volume 16, Issue 8, 12 2 2021, Pages e0255466
The interobserver agreement of ECG abnormalities using Minnesota codes in people with type 2 diabetes.
Nijpels G, van der Heijden AAWA, Elders P, Beulens JWJ, Beulens JWJ, de Vet HCW
Objectives: To assess the interobserver agreement in categories of electrocardiogram (ECG) abnormalities using the Minnesota Code criteria. Methods: We used a random sample of 180 ECGs from people with type 2 diabetes. ECG abnormalities were classified and coded using the Minnesota ECG Classification. Each ECG was independently rated on several abnormalities by an experienced rater (rater 1) and by two cardiologists (raters 2 and 3) trained to apply the Minnesota codes on four Minnesota codes; 1...
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 14, Issue 8, 12 2 2021, Pages e012612
Hemodynamic Consequences of an Undersized Extracardiac Conduit in an Adult Fontan Patient Revealed by 4-Dimensional Flow Magnetic Resonance Imaging.
Rijnberg FM, van Assen HC, Hazekamp MG, Roest AAW, Westenberg JJM
Abstract
Cited 13 times since 2021 (3.6 per year)
source: EuropePMC
American journal of physiology. Lung cellular and molecular physiology,
Volume 321, Issue 4, 11 2 2021, Pages L775-L786
Disease modeling following organoid-based expansion of airway epithelial cells.
Eenjes E, van Riet S, Kroon AA, Slats AM, Khedoe PPSJ, Boerema-de Munck A, Buscop-van Kempen M, Ninaber DK, Reiss IKM, Clevers H, Rottier RJ, Hiemstra PS
Air-liquid interface (ALI) cultures are frequently used in lung research but require substantial cell numbers that cannot readily be obtained from patients. We explored whether organoid expansion [three-dimensional (3D)] can be used to establish ALI cultures from clinical samples with low epithelial cell numbers. Airway epithelial cells were obtained from tracheal aspirates (TA) from preterm newborns and from bronchoalveolar lavage (BAL) or bronchial tissue (BT) from adults. TA and BAL cells wer...
Abstract
Cited 26 times since 2021 (7.3 per year)
source: EuropePMC
Diabetes,
Volume 70, Issue 11, 10 2 2021, Pages 2683-2693
Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study.
Slieker RC, Donnelly LA, Fitipaldi H, Bouland GA, Giordano GN, Åkerlund M, Gerl MJ, Ahlqvist E, Ali A, Dragan I, Elders P, Festa A, Hansen MK, van der Heijden AA, Mansour Aly D, Kim M, Kuznetsov D, Mehl F, Klose C, Simons K, Pavo I, Pullen TJ, Suvitaival T, Wretlind A, Rossing P, Lyssenko V, Legido Quigley C, Groop L, Thorens B, Franks PW, Ibberson M, Rutter GA, Beulens JWJ, 't Hart LM, Pearson ER
Type 2 diabetes is a multifactorial disease with multiple underlying aetiologies. To address this heterogeneity, investigators of a previous study clustered people with diabetes according to five diabetes subtypes. The aim of the current study is to investigate the etiology of these clusters by comparing their molecular signatures. In three independent cohorts, in total 15,940 individuals were clustered based on five clinical characteristics. In a subset, genetic (N = 12,828), metabolomic (N = 2...
Abstract
Cited 8 times since 2021 (2.2 per year)
source: EuropePMC
European heart journal open,
Volume 1, Issue 2, 9 2 2021, Pages oeab018
Segmental assessment of blood flow efficiency in the total cavopulmonary connection using four-dimensional flow magnetic resonance imaging: vortical flow is associated with increased viscous energy loss rate.
Rijnberg FM, Juffermans JF, Hazekamp MG, Helbing WA, Lamb HJ, Roest AAW, Westenberg JJM, van Assen HC
Aims: To study flow-related energetics in multiple anatomical segments of the total cavopulmonary connection (TCPC) in Fontan patients from four-dimensional (4D) flow magnetic resonance imaging (MRI), and to study the relationship between adverse flow patterns and segment-specific energetics. Methods and results: Twenty-six extracardiac Fontan patients underwent 4D flow MRI of the TCPC. A segmentation of the TCPC was automatically divided into five anatomical segments [conduit, superior vena cav...
Abstract
Cited 32 times since 2021 (9 per year)
source: EuropePMC
Anaesthesia,
Volume 76, Issue 11, 9 2 2021, Pages 1454-1464
Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study.
COVIDSurg Collaborative, GlobalSurg Collaborative
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjust...
Abstract
Cited 10 times since 2021 (2.8 per year)
source: EuropePMC
Placenta,
Volume 112, 8 2 2021, Pages 189-196
Placenta morphology and biomarkers in pregnancies with congenital heart disease - A systematic review.
Snoep MC, Aliasi M, van der Meeren LE, Jongbloed MRM, DeRuiter MC, Haak MC
Impaired placentation is an important contributing factor to intra-uterine growth restriction and pre-eclampsia in fetuses with congenital heart defects (CHD). These pregnancy complications occur more frequently in pregnancies with fetal CHD. One of the most important factors influencing the life of children with CHD is neurodevelopmental delay, which seems to start already in utero. Delayed neurodevelopment in utero may be correlated or even (partly) explained by impaired placentation in CHD ca...
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
International journal of cardiology,
Volume 341, 8 2 2021, Pages 31-38
Determinants of exercise limitation in contemporary paediatric Fontan patients with an extra cardiac conduit.
Harteveld LM, Blom NA, Terol Espinosa de Los Monteros C, van Dijk JG, Kuipers IM, Rammeloo LAJ, de Geus EJC, Hazekamp MG, Ten Harkel ADJ
Background: Although various determinants of exercise limitation in Fontan patients have been studied, most research has been performed in patients who underwent different surgical procedures with differing haemodynamic characteristics. The aim of the current study was to evaluate non-invasively measured cardiovascular parameters and their influence on exercise performance in paediatric Fontan patients with an extracardiac conduit and moderate-good systolic ventricular function. Methods: Fontan...
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
ESC heart failure,
Volume 8, Issue 5, 6 1 2021, Pages 3539-3546
Sex differences in prognosis of significant secondary mitral regurgitation.
Namazi F, van der Bijl P, Vo NM, van Wijngaarden SE, Ajmone Marsan N, Delgado V, Bax JJ
Aims: Secondary mitral regurgitation (MR) is more frequent in men than in women. However, little is known about differences in prognosis between men and women with secondary MR. The objective of this study is to investigate the sex distribution of secondary MR and the prognostic differences between sexes. Methods: Patients with significant secondary MR, of both ischaemic and non-ischaemic aetiologies, were identified through the departmental electronic patient files and retrospectively analysed....
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 157, 6 1 2021, Pages 15-21
Changes in Global Left Ventricular Myocardial Work Indices and Stunning Detection 3 Months After ST-Segment Elevation Myocardial Infarction.
Lustosa RP, Fortuni F, van der Bijl P, Mahdiui ME, Montero-Cabezas JM, Kostyukevich MV, Knuuti J, Marsan NA, Delgado V, Bax JJ
Global left ventricular (LV) myocardial work (MW) indices (GLVMWI) are derived from speckle tracking echocardiographic strain data in combination with non-invasive blood pressure measurements. Changes in global work index (GWI), global constructive work (GCW), global wasted work (GWW) and global work efficiency (GWE) after ST-segment elevation myocardial infarction (STEMI) have not been explored. The aim of present study was to assess the evolution of GLVMWI in STEMI patients from baseline (inde...
Abstract
