6743 results
Cited 3 times since 2025 (4.8 per year)
source: EuropePMC
Interdisciplinary cardiovascular and thoracic surgery,
Volume 40, Issue 3, 1 1 2025, Pages ivaf009
Survival outcomes after surgery for type A aortic dissection: a contemporary Dutch nationwide registry study.
Timmermans PT, Velders BJJ, Groenwold RHH, Vos RJ, Roefs MM, Braun J, Klautz RJM, Mecozzi G, Hjortnaes J, Cardiothoracic Surgery Registration Committee and the Aortic Surgery Work Group of the Netherlands Heart Registration
Objectives: To describe the nationwide survival outcomes after surgery for type A aortic dissection. Methods: All patients who underwent surgery for type A aortic dissection in the Netherlands between 2018 and 2021 were identified in the Netherlands Heart Registration (NHR) database. The NHR data were linked to lifelong survival data from Statistics Netherlands (98% match). Time trends for in-hospital and mid-term mortality were described, and age- and sex-adjusted regression analysis was perfor...
Abstract
Cited 7 times since 2025 (11.2 per year)
source: EuropePMC
Preventive veterinary medicine,
Volume 239, 28 4 2025, Pages 106493
The impact of bluetongue serotype 3 on cattle mortality, abortions and premature births in the Netherlands in the first year of the epidemic.
van den Brink KMJA, Brouwer-Middelesch H, van Schaik G, Lam TJGM, Stegeman JA, van den Brom R, Spierenburg MAH, Santman-Berends IMGA
In September 2023, bluetongue virus serotype 3 (BTV-3) was identified among sheep and cattle in the Netherlands. Severe clinical signs and increased mortality were reported in sheep and cattle. The aim of this study was to quantify the impact of BTV-3 on mortality, abortions and premature births in cattle in the Netherlands in 2023. Data were available from 1 January 2020-31 December 2023 and were aggregated at herd-month level. Cattle herds were assigned a BTV-3 status for each herd-month: 1) h...
Abstract
British journal of anaesthesia,
Volume 134, Issue 4, 28 4 2025, Pages 1009-1017
Regulation of cerebrovascular resistance below the lower limit of cerebral autoregulation during induced hypotension: an observational study.
Kho E, van den Dool REC, Mahes SS, Corsmit OT, Vlaar APJ, Koolbergen DR, Veelo DP, Sperna Weiland NH, Immink RV
Background: To maintain adequate perfusion, cerebral blood flow (CBF) is preserved by changes in cerebrovascular resistance (CVR) inversely related to fluctuations in mean arterial blood pressure (MAP). It has been hypothesised that during progressive hypotension, a lower limit of cerebral autoregulation (LLCA) is reached beyond which cerebrovascular dilation becomes exhausted and CBF starts to decrease together with BP. We tested this hypothesis by assessing CVR above and below the LLCA. Method...
Abstract
Endocrine connections,
Volume 14, Issue 4, 27 4 2025, Pages e240533
BMI trajectories in the first 3 months after childhood craniopharyngioma resection: a plea for early management of BMI changes.
Hulsmann SC, Hoving EW, Bakker B, Janssens GO, van Schaik J, de Vos-Kerkhof E, Tissing WJE, van Santen HM
Objective: Hypothalamic obesity (HO) is a severe condition following childhood craniopharyngioma (cCP) treatment. Despite multidisciplinary and centralized care, severe body mass index (BMI) changes are still often encountered after cCP surgery. We aimed to perform an in-depth analysis of BMI trajectories in our cCP cohort in the first year after surgery and to identify characteristics associated with BMI change. Methods: Data were collected of cCP patients diagnosed since January 2018. Change (...
Abstract
STAR protocols,
Volume 6, Issue 1, 27 4 2025, Pages 103679
Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes.
Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, Wu JC, Sluijter JPG, Wu SM, Buikema JW
Abstract
JACC. Advances,
Volume 4, Issue 3, 26 4 2025, Pages 101633
Developing a Systematic Approach for the Implementation of Medical Extended Reality Learning Modules in Cardiothoracic Health Care: Recommendations From an International Expert Group.
Mahtab EAF, Max SA, Braun J, Regeer MV, Kaufman B, Dunning J, Bibleraaj B, Andreas M, Rodríguez Lecoq R, Klinceva M, Rosalia R, Lorusso R, Bruining N, Egorova AD
Extended reality (XR) modalities in health care are quickly evolving. There is a lack of systematically described developmental process and the "how to" execute a business-case guidance. This article formulates a systematic approach on the technical developmental steps and generation of business-case to guide the iterative development of an XR tool. An international expert group was established and several available frameworks related to entrepreneurship and business-case development w...
Abstract
Cited 1 times since 2025 (1.6 per year)
source: EuropePMC
European heart journal. Digital health,
Volume 6, Issue 3, 26 4 2025, Pages 496-507
The environmental impact of telemonitoring vs. on-site cardiac follow-up: a mixed-method study.
van Bree EM, Snijder LE, Ter Haak S, Atsma DE, Brakema EA
Aims: Digital health technologies are considered promising innovations to reduce healthcare's environmental footprint. However, this assumption remains largely unstudied. We compared the environmental impact of telemonitoring and care on site (CoS) in post-myocardial infarction (MI) follow-up and explored how it influenced patients' and healthcare professionals' (HPs) perceptions of using telemonitoring. Methods and results: We conducted a mixed-method study; a standardized life c...
Abstract
Cited 1 times since 2025 (1.6 per year)
source: EuropePMC
PloS one,
Volume 20, Issue 2, 26 4 2025, Pages e0317826
The value of vector ECG in predicting residual pulmonary hypertension in CTEPH patients after pulmonary endarterectomy.
Luijten D, Rodenburg T, Bogaard HJ, Kianzad A, Ruigrok D, Croon P, Smeele P, Vliegen HW, Vonk Noordegraaf A, Meijboom LJ, Klok FA
Introduction: Right heart catheterization (RHC) is the diagnostic standard for establishing residual pulmonary hypertension (PH) after pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH). A potential non-invasive alternative diagnostic test could be electrocardiography (ECG)-derived ventricular gradient optimized for right ventricular pressure overload (VG-RVPO). Methods: We studied 66 CTEPH patients who underwent PEA. A subgroup of 20 patients a...
Abstract
Cited 1 times since 2025 (1.6 per year)
source: EuropePMC
Molecular oncology,
Volume 19, Issue 8, 22 4 2025, Pages 2348-2365
Adverse prognosis gene expression patterns in metastatic castration-resistant prostate cancer.
Sharifi MN, Feng E, Rydzewski NR, Taylor AK, Sperger JM, Shi Y, Helzer KT, Bootsma ML, Carreno V, Chang AH, Nunamaker LA, Blitzer GC, Shang TA, Subramanian A, Bjartell A, Josefsson A, Wikström P, Feng E, Kohli M, Yang R, Dehm SM, Small EJ, Aggarwal R, Quigley DA, Lang JM, Zhao SG, Sjöström M
Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease. Several studies have identified transcriptional subtypes of mCRPC, but comprehensive analysis of prognostic gene expression pathways has been limited. Therefore, we aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression-based pathways with clinical outcomes and intrapatient and intratumor heterogeneity. Survival data were obtained for 272 patients. P...
Abstract
Cited 1 times since 2025 (1.5 per year)
source: EuropePMC
Journal of cardiothoracic and vascular anesthesia,
Volume 39, Issue 6, 21 3 2025, Pages 1451-1463
Vasoplegia in Cardiac Surgery: A Systematic Review and Meta-analysis of Current Definitions and Their Influence on Clinical Outcomes.
Papazisi O, van der Schoot MM, Berendsen RR, Arbous SM, le Cessie S, Dekkers OM, Klautz RJM, Marczin N, Palmen M, de Waal EEC
Objectives: To identify differences in the reported vasoplegia incidence, intensive care unit (ICU) length of stay (LOS), and 30-day mortality rates as influenced by different vasoplegia definitions used in cardiac surgery studies. Design: A systematic review was performed covering the period 1977 to 2023 using PubMed/MEDLINE, Embase, Web of Science, Cochrane Library, and Emcare and a meta-analysis (PROSPERO: CRD42021258328) was performed. Setting and participants: One hundred studies defining v...
Abstract
Cited 1 times since 2025 (1.5 per year)
source: EuropePMC
Gynecologic oncology,
Volume 194, 20 3 2025, Pages 86-90
Predicting lymph node metastases in three different vulvar squamous cell carcinoma subgroups.
van Velzen AF, Tulling AJ, van Poelgeest MIE, Bosse T, van Doorn HC, Kortekaas KE, Nooij LS
Objective: This study aimed to analyze the risk of lymph node metastases (LNM) in three different VSCC subgroups (HPV-positive (HPVpos), HPV-negative p53 wildtype (HPVneg/p53wt) and HPV-negative p53 abnormal (HPVneg/p53abn)), and develop a predictive model for clinical use. Methods: A retrospective cohort study was performed, collecting data from all surgically treated VSCC patients between 2000 and 2022 from two oncology clinics. The primary outcome was the risk of groin LNM at diagnosis. Progn...
Abstract
Cited 1 times since 2025 (1.5 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 18, Issue 3, 20 3 2025, Pages e013099
Characteristics of Patients With the Arrhythmogenic Mitral Valve Prolapse Syndrome and Sudden Cardiac Arrest and Sustained Ventricular Arrhythmias.
Chakrabarti A, Giudicessi JR, Ezzeddine FM, Delling FN, Dixit S, Lee YJ, Muser D, Magnani S, Van Wijngaarden A, Ajmone Marsan N, Miller MA, Gandhi J, Trivieri MG, Font J, Martins R, McCaffrey JA, Santangeli P, Marchlinski FE, Chapagain H, Mathew D, Mathew D, Kancharla K, Syed FF, Abid A, Cerbin L, Tzou WS, Garg L, Della Rocca DG, Natale A, Mohanty S, Sheldon SH, Kuo L, Haugaa KH, Aabel EW, Enriquez A, Maeda S, Deshmukh A, Ghannam M, Bogun F, Ackerman MJ, Liang JJ
Background: Patients with arrhythmogenic mitral valve prolapse syndrome are at increased risk for life-threatening ventricular arrhythmias, but studies have been limited by small sample sizes. We sought to assemble an international arrhythmogenic mitral valve prolapse syndrome registry to delineate the clinical, imaging, and treatment characteristics of patients with arrhythmogenic mitral valve prolapse syndrome who survived sudden cardiac arrest (SCA) or had sustained ventricular tachycardia (V...
Abstract
Journal of cardiovascular development and disease,
Volume 12, Issue 2, 18 3 2025, Pages 78
Beyond Survival: Assessing Quality of Life, Activity Level, and Ethnic Diversity in Aortic Dissection Survivors.
Bacour N, van Erp O, Grewal S, Tirpan AU, Eberl S, Yeung KK, Balm R, Verwoert GC, Driessen AHG, Klautz RJM, Grewal N
Background: An acute aortic dissection (AAD) is a highly lethal condition that demands immediate medical intervention. Survivors often face significant long-term challenges. While immediate survival remains a critical focus in acute care settings, little is known about long-term results, especially with regard to activity levels, post-operative quality of life, and the impact of cultural and ethnic characteristics on recovery. Using data from the Dutch National Aortic Dissection Survivor's...
Abstract
Journal of imaging,
Volume 11, Issue 2, 18 3 2025, Pages 65
Impact of Data Capture Methods on 3D Reconstruction with Gaussian Splatting.
Rangelov D, Waanders S, Waanders K, Keulen MV, Miltchev R
This study examines how different filming techniques can enhance the quality of 3D reconstructions with a particular focus on their use in indoor crime scene investigations. Using Neural Radiance Fields (NeRF) and Gaussian Splatting, we explored how factors like camera orientation, filming speed, data layering, and scanning path affect the detail and clarity of 3D reconstructions. Through experiments in a mock crime scene apartment, we identified optimal filming methods that reduce noise and art...
Abstract
Imaging neuroscience (Cambridge, Mass.),
Volume 3, 18 3 2025, Pages imag_a_00474
Exploring neuroendocrine influences on the sensorimotor-association axis in a female and a male individual.
Serio B, Yilmaz D, Pritschet L, Grotzinger H, Jacobs EG, Eickhoff SB, Valk SL
Human neuroimaging studies consistently show multimodal patterns of variabilityalong a key principle of macroscale cortical organization-thesensorimotor-association (S-A) axis. However, little is known about day-to-dayfluctuations in functional activity along this axis within an individual,including sex-specific neuroendocrine factors contributing to such transientchanges. We leveraged data from two densely sampled healthy young adults, onefemale and one male, to investigate intra-individual dai...
Abstract
International archives of allergy and immunology,
Volume 186, Issue 10, 18 3 2025, Pages 984-992
A Growing Cause of Food Allergies in Children: Sesame.
Aytekin Güvenir F, Aytekin Güvenir F, Yörüsün G, Geniş C, Yılmaz D, Selmanoğlu A, Şengül Emeksiz Z, Dibek Mısırlıoğlu E
Introduction: Sesame allergy has been seen with increasing frequency in recent years and is one of the important causes of food anaphylaxis. The aim of our study was to examine the clinical and laboratory features of patients with sesame allergy and to evaluate the characteristics of sesame-related anaphylaxis. Methods: Patients diagnosed with sesame allergy at Ankara Bilkent City Hospital between January 2017 and June 2024 were included in the study. Demographic, clinical, and laboratory data o...
Abstract
Cited 1 times since 2025 (1.5 per year)
source: EuropePMC
The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland,
Volume 23, Issue 2, 18 3 2025, Pages 78-86
Surgeon personality diversity across generations and subspecialties.
Sier VQ, Schmitz RF, Wertenbroek RWAM, Schepers A, van der Vorst JR, SUPER Collaborators
Background: Traditional exploration of surgical professionals' personality traits focuses on general characteristics at the domain-level of the five-factor model. Personality has been related to clinically-relevant areas such as clinical decision-making and team effectiveness, yet there is limited insight in the personality of surgeons at the facet-level of the Big Five. Here, we performed a large-scale study examining domain- and facet-variations of personality in four surgical generations...
Abstract
Structural heart : the journal of the Heart Team,
Volume 9, Issue 5, 17 3 2025, Pages 100428
Conduction Disorders After Transcatheter Aortic Valve Implantation: Evolution Over Time and Association With Long-Term Outcomes.
Chua AP, Myagmardorj R, Nabeta T, Kuneman JH, van der Kley F, Bax JJ, Ajmone Marsan N
Background: Expanding indications for transcatheter aortic valve implantation (TAVI) highlighted the importance of complications such as new left bundle branch block (LBBB) or permanent pacemaker (PPM) implantation. However, studies on the long-term outcomes of these conduction abnormalities (CA) are limited. This study aims to examine the progression of CA within the first year after TAVI and their long-term prognostic value. Methods: TAVI patients were divided into 1) PPM implantation within t...
Abstract
The Journal of thoracic and cardiovascular surgery,
Volume 170, Issue 4, 17 3 2025, Pages 1025-1034
Valve-sparing aortic root replacement in bicuspid aortic valves-the reimplantation technique: A multicenter study.
Arabkhani B, Boodhwani M, De Paulis R, Chen EP, Koolbergen D, Mastrobuoni S, Aphram G, Salica A, Jahanyar J, El Khoury G, de Kerchove L
Objective: Reported outcomes in patients with bicuspid aortic valves (BAVs) undergoing valve-sparing aortic root replacement (VSRR) are scarce. This study aims to evaluate outcomes in patients with BAV using the reimplantation (David) technique. Methods: Consecutive adult patients with BAV, aortic root aneurysm, and/or aortic valve insufficiency (AI) undergoing VSRR (reimplantation) were included from 5 centers experienced in reimplantation procedures. Patients were subcategorized into 2 groups...
Abstract
Open heart,
Volume 12, Issue 1, 17 3 2025, Pages e002846
Clinical use and impact of mechanical circulatory support for myocardial infarction-related cardiogenic shock in the Netherlands: a registry-based propensity-matched analysis.
Bogerd M, Griffioen AM, Bunge JJH, Peters EJ, Ten Berg S, Timmermans MJC, Kraaijeveld AO, Lipsic E, Otterspoor LC, Bleeker G, Montero-Cabezas JM, Sjauw KD, Meuwissen M, Dubois EA, van Geuns RM, Henriques JPS, PCI Registration Committee of the Netherlands Heart Registration
Background: Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes. Methods: This real-world, multicentre registry included CS patients undergoing percutaneous coronary intervention between 2017 and 2021 in 14 Dutch hospitals. The impact on clinical outcomes was analysed aft...
Abstract
