6177 results
Cited 8 times since 2004 (0.4 per year)
source: EuropePMC
International journal of psychiatry in clinical practice,
Volume 8, Issue 4, 1 1 2004, Pages 205-211
A prospective randomized single-blind, multicenter trial comparing the efficacy and safety of paroxetine with and without quetiapine therapy in depression associated with anxiety.
Yargic LI, Corapcioglu A, Kocabasoglu N, Erdogan A, Koroglu G, Yilmaz D
OBJECTIVE To evaluate quetiapine as an adjunct to paroxetine in patients with comorbid depression and anxiety. METHOD Prospective, multicenter, single-blind trial of patients with DSM-IV major depression and associated anxiety, who were randomized to an 8-week treatment with paroxetine alone (n=54) or paroxetine+quetiapine (n=58). Quetiapine was dosed to 200 mg/day and paroxetine to 60 mg/day, as required. RESULTS Decrease in HAM-A scores was significantly greater in the combined therapy group t...
Abstract
Cited 127 times since 2004 (6 per year)
source: EuropePMC
The American journal of medicine,
Volume 116, Issue 2, 1 1 2004, Pages 96-103
Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery.
Kertai MD, Boersma E, Westerhout CM, van Domburg R, Klein J, Bax JJ, van Urk H, Poldermans D
Purpose: To assess the potential long-term beneficial effects of statin use after successful abdominal aortic surgery. Methods: Between 1991 and 2001, 570 patients underwent abdominal aortic aneurysm repair at the Erasmus Medical Center. Of the 519 patients (91%) who survived surgery beyond 30 days, 510 (98%) were followed for a median of 4.7 years (interquartile range, 2.7 to 7.3 years). These patients were evaluated for use of statins and beta-blockers, and for clinical risk factors (e.g., adv...
Abstract
Cited 99 times since 2004 (4.6 per year)
source: EuropePMC
The American journal of medicine,
Volume 116, Issue 1, 1 1 2004, Pages 8-13
Aortic stenosis: an underestimated risk factor for perioperative complications in patients undergoing noncardiac surgery.
Kertai MD, Bountioukos M, Boersma E, Bax JJ, Thomson IR, Sozzi F, Klein J, Roelandt JR, Poldermans D
Purpose: To determine the incidence of perioperative events in patients with aortic stenosis undergoing noncardiac surgery. Methods: We studied 108 patients with moderate (mean gradient, 25 to 49 mm Hg) or severe (mean gradient, > or =50 mm Hg) aortic stenosis and 216 controls who underwent noncardiac surgery between 1991 and 2000 at Erasmus Medical Center. Controls were selected based on calendar year and type of surgery. Details of clinical risk factors, type of surgery, and perioperative m...
Abstract
Cited 25 times since 2004 (1.2 per year)
source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,
Volume 6, Issue 4, 1 1 2004, Pages 767-776
Accurate and reproducible mitral valvular blood flow measurement with three-directional velocity-encoded magnetic resonance imaging.
Westenberg JJ, Danilouchkine MG, Doornbos J, Bax JJ, van der Geest RJ, Labadie G, Lamb HJ, Versteegh MI, de Roos A, Reiber JH
A new method for quantifying the transvalvular flow through the mitral valve (MV) based on three-directional velocity-encoded magnetic resonance imaging (MRI) is presented. For thirty time phases during one cardiac cycle, the three-dimensional (3D) velocity vector field of the blood flow is reconstructed from the MRI measurement. Retrospectively, for each time phase, the MV-plane is indicated manually in the velocity data and the flow through this plane is determined, representing the MV flow. M...
Abstract
Cited 11 times since 2004 (0.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 93, Issue 1, 1 1 2004, Pages 14-17
Incidence of recovery of contractile function following revascularization in patients with ischemic left ventricular dysfunction.
Schinkel AF, Poldermans D, Vanoverschelde JL, Elhendy A, Boersma E, Roelandt JR, Bax JJ
Contractile function in patients with ischemic left ventricular (LV) dysfunction may improve after myocardial revascularization. Currently, the incidence of contractile function recovery after revascularization in these patients is unclear. The aim of this study was to assess the incidence of function improvement after myocardial revascularization in patients with ischemic LV dysfunction. A total of 258 consecutive patients (aged 59 +/- 12 years) with severely depressed LV ejection fractions (EF...
Abstract
Cited 80 times since 2004 (3.8 per year)
source: EuropePMC
The Journal of clinical endocrinology and metabolism,
Volume 89, Issue 1, 1 1 2004, Pages 71-75
Increased prevalence of regurgitant valvular heart disease in acromegaly.
Pereira AM, van Thiel SW, Lindner JR, Roelfsema F, van der Wall EE, Morreau H, Smit JW, Romijn JA, Bax JJ
Cardiac involvement is common in acromegaly, but the prevalence of valvular abnormalities in patients with acromegaly has not been documented and is the topic of this study. In a prospective study design, 40 consecutive patients with acromegaly and 120 control subjects (matched for age, sex, hypertension, and left ventricular systolic function) were studied. All patients and controls were evaluated using conventional two-dimensional and Doppler echocardiography. Significant valve disease was mor...
Abstract
Cited 20 times since 2004 (0.9 per year)
source: EuropePMC
Anesthesiology,
Volume 100, Issue 1, 1 1 2004, Pages 4-7
Is there any reason to withhold beta blockers from high-risk patients with coronary artery disease during surgery?
Kertai MD, Bax JJ, Klein J, Poldermans D
Abstract
Cited 139 times since 2003 (6.5 per year)
source: EuropePMC
Circulation,
Volume 109, Issue 3, 29 5 2004, Pages 393-398
Toll-like receptor 4 is involved in outward arterial remodeling.
Hollestelle SC, De Vries MR, Van Keulen JK, Schoneveld AH, Vink A, Strijder CF, Van Middelaar BJ, Pasterkamp G, Quax PH, De Kleijn DP
Background: Toll-like receptor 4 (Tlr4) is the receptor for exogenous lipopolysaccharides (LPS). Expression of endogenous Tlr4 ligands, heat shock protein 60 (Hsp60) and extra domain A of fibronectin, has been observed in arthritic and oncological specimens in which matrix turnover is an important feature. In atherosclerosis, outward remodeling is characterized by matrix turnover and a structural change in arterial circumference and is associated with a vulnerable plaque phenotype. Since Tlr4 li...
Abstract
Cited 2 times since 2003 (0.1 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 19, Issue 6, 1 1 2003, Pages 529-531
Viability assessment: nuclear imaging vs. dobutamine echocardiography.
Bax JJ, van der Wall EE
Abstract
Cited 41 times since 2003 (1.9 per year)
source: EuropePMC
European journal of heart failure,
Volume 5, Issue 6, 1 1 2003, Pages 767-774
Screening for left ventricular dysfunction using a hand-carried cardiac ultrasound device.
Vourvouri EC, Schinkel AF, Roelandt JR, Boomsma F, Sianos G, Bountioukos M, Sozzi FB, Rizzello V, Bax JJ, Karvounis HI, Poldermans D
Background: The hand-carried cardiac ultrasound (HCU) device is a recently introduced imaging device, which may be potentially useful in the primary care setting. Aim: To test the screening potential of a HCU for the detection of left ventricular (LV) dysfunction by evaluating LV ejection fraction (LVEF) and inferior vena cava (IVC) collapse. Standard echocardiographic system (SE) and plasma brain natriuretic peptide (BNP) measurements were used as a reference. Methods: Eighty-eight consecutive...
Abstract
Cited 11 times since 2003 (0.5 per year)
source: EuropePMC
Nuklearmedizin. Nuclear medicine,
Volume 42, Issue 6, 1 1 2003, Pages 240-243
Iodine excretion during stimulation with rhTSH in differentiated thyroid carcinoma.
Löffler M, Weckesser M, Franzius C, Kies P, Schober O
Aim: Elevated iodine intake is a serious problem in the diagnostic and therapeutic application of (131)iodine in patients with differentiated thyroid cancer. Therefore, iodine avoidance is necessary 3 months in advance. Additionally, endogenous stimulation requires withdrawal of thyroid hormone substitution for 4 weeks. Exogenous stimulation using recombinant human TSH (rhTSH) enables the continuous substitution of levothyroxine, which contains 65.4% of its molecular weight in iodine. Thus, a su...
Abstract
Cited 5 times since 2003 (0.2 per year)
source: EuropePMC
Lancet (London, England),
Volume 362, Issue 9401, 1 1 2003, Pages 2118-9; author reply 2119-20
Selective decontamination of digestive tract in intensive care.
Bonten MJ, Kluytmans J, de Smet AM, Bootsma M, Hoes A
Abstract
Cited 37 times since 2003 (1.7 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 60, Issue 4, 1 1 2003, Pages 452-457
Randomized study to compare balloon angioplasty and elective stent implantation in venous bypass grafts: the Venestent study.
Hanekamp CE, Koolen JJ, Den Heijer P, Schalij MJ, Piek JJ, Bär FW, De Scheerder I, Bonnier HJ, Pijls NH, Venestent Study Group
The aim of the study was to compare acute and long-term angiographic and clinical outcome of balloon angioplasty and elective stenting in de novo lesions in the body of a saphenous vein graft (SVG). A total of 150 patients, with de novo lesions in SVG, were randomly assigned to balloon angioplasty or elective Wiktor I stent implantation. The angiographic restenosis rate at 6-month follow-up was 32.8% in the balloon group and 19.1% in the stent group (P = 0.069). At 1-year follow-up, target vesse...
Abstract
The international journal of cardiovascular imaging,
Volume 19, Issue 6, 1 1 2003, Pages 549-552
MR imaging in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
van der Wall EE, Schalij MJ
Abstract
Cited 61 times since 2003 (2.8 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 126, Issue 6, 1 1 2003, Pages 2003-2010
Decellularization of rat aortic valve allografts reduces leaflet destruction and extracellular matrix remodeling.
Grauss RW, Hazekamp MG, van Vliet S, Gittenberger-de Groot AC, DeRuiter MC
Objectives: Decellularization of aortic valve allografts in advance of transplantation is a promising approach to overcome immune-induced early graft failure. In this study the effects of in vitro cell extraction on extracellular matrix molecules and in vivo remodeling of decellularized aortic valves were investigated in a heterotopic aortic valve rat implantation model. Methods: Rat aortic valve conduits were decellularized by a 2-step detergent-enzymatic extraction method involving sodium dode...
Abstract
Cited 29 times since 2003 (1.4 per year)
source: EuropePMC
Journal of virology,
Volume 77, Issue 24, 1 1 2003, Pages 12996-13004
Intra- and intermolecular disulfide bonds of the GP2b glycoprotein of equine arteritis virus: relevance for virus assembly and infectivity.
Wieringa R, De Vries AA, Post SM, Rottier PJ
Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus belonging to the family Arteriviridae of the order NIDOVIRALES: EAV virions contain six different envelope proteins. The glycoprotein GP(5) (previously named G(L)) and the unglycosylated membrane protein M are the major envelope proteins, while the glycoproteins GP(2b) (previously named G(S)), GP(3), and GP(4) are minor structural proteins. The unglycosylated small hydrophobic envelope protein E is present in virus particles...
Abstract
Minerva cardioangiologica,
Volume 51, Issue 6, 1 1 2003, Pages 667-676
Myocardial tissue Doppler echocardiography and cardiac resynchronization therapy.
Molhoek SG, Schalij MJ, Van Der Wall EE, Bax JJ
Cardiac resynchronization therapy (CRT) is a promising technique for patients with end-stage, drug-refractory heart failure. Still 20-30% of the patients treated with CRT do not respond. Accordingly, the current selection criteria need to be refined, and it appears that demonstration of left ventricular dyssynchrony may be mandatory for response to CRT. Novel echocardiographic methods are currently investigated to detect left ventricular dyssynchrony and thereby improve the selection of candidat...
Abstract
Cited 24 times since 2003 (1.1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 92, Issue 11, 1 1 2003, Pages 1267-1270
Long-term prognosis after normal dobutamine stress echocardiography.
Sozzi FB, Elhendy A, Roelandt JR, van Domburg RT, Schinkel AF, Vourvouri EC, Bax JJ, Rizzello V, Poldermans D
Patients with normal dobutamine stress echocardiography (DSE) were shown to have a favorable outcome at an intermediate-term follow-up. However, there are scarce data regarding long-term survival after normal DSE. This study sought to assess the long-term outcome after normal DSE. We studied 401 patients (age 62 +/- 10 years, 264 men) who had a normal echocardiogram at rest and with high-dose dobutamine stress. End points during a mean follow-up of 5 +/- 1.7 years (minimum 3.5) were all-cause mo...
Abstract
Cited 4 times since 2003 (0.2 per year)
source: EuropePMC
Pediatric nephrology (Berlin, Germany),
Volume 19, Issue 2, 25 4 2003, Pages 237-239
Fulminant meningococcemia and acute renal failure in a 3-year-old boy.
Akil I, Yüksel H, Coskun S, Yilmaz D, Onag A
Acute renal failure is a common occurrence in sepsis, but is rarely reported in meningococcemia. We present a young child diagnosed with fulminant meningococcemia who had several poor prognostic factors, including hypotension, thrombocytopenia, purpura fulminans, seizures, the absence of meningitis with meningococcemia, and acute renal failure, which was successfully treated with peritoneal dialysis. Peritoneal dialysis was started on the 5th day because the patient had been anuric for 48 h. At...
Abstract
Cited 51 times since 2003 (2.4 per year)
source: EuropePMC
Molecular biology of the cell,
Volume 15, Issue 2, 14 2 2003, Pages 611-624
Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes.
Fouraux MA, Deneka M, Ivan V, van der Heijden A, Raymackers J, van Suylekom D, van Venrooij WJ, van der Sluijs P, Pruijn GJ
We describe the characterization of an 80-kDa protein cross-reacting with a monoclonal antibody against the human La autoantigen. The 80-kDa protein is a variant of rabip4 with an N-terminal extension of 108 amino acids and is expressed in the same cells. For this reason, we named it rabip4'. rabip4' is a peripheral membrane protein, which colocalized with internalized transferrin and EEA1 on early endosomes. Membrane association required the presence of the FYVE domain and was perturb...
Abstract
