Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6177 results
Cited 150 times since 2003 (6.8 per year) source: EuropePMC
Circulation, Volume 107, Issue 19, 12 2 2003, Pages 2416-2421 Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events. Boekholdt SM, Agema WR, Peters RJ, Zwinderman AH, van der Wall EE, Reitsma PH, Kastelein JJ, Jukema JW, REgression GRowth Evaluation Statin Study Group
Background: Atherosclerosis is increasingly considered to be a chronic inflammatory process. We examined whether genetic variants of the toll-like receptor 4 (TLR4), which are correlated with impaired innate immunity and with progression of carotid atherosclerosis, are also associated with coronary atherosclerosis and predict the risk of cardiovascular events. Methods and results: Two polymorphisms of the TLR4 gene (Asp299Gly and Thr399Ile) were determined in 655 men with angiographically docume... Abstract
Cited 25 times since 2003 (1.1 per year) source: EuropePMC
Atherosclerosis, Volume 168, Issue 1, 1 1 2003, Pages 131-138 A novel functional polymorphism in the PECAM-1 gene (53G>A) is associated with progression of atherosclerosis in the LOCAT and REGRESS studies. Elrayess MA, Webb KE, Flavell DM, Syvänne M, Taskinen MR, Frick MH, Nieminen MS, Kesäniemi YA, Pasternack A, Jukema JW, Kastelein JJ, Zwinderman AH, Humphries SE
A 53G>A polymorphism identified in the 5' untranslated region (5'UTR) of the platelet endothelial cell adhesion molecule-1 (PECAM-1) gene alters a putative shear stress responsive element (SSRE). PECAM-1 was shown to be responsive to shear stress and transient transfection of human umbilical vein endothelial cell (HUVECs) with two luciferase reporter constructs driven by the PECAM-1 promoter and 5'UTR showed a response of the 53G allele, not the 53A allele, to shear stress. Ass... Abstract
Cited 7 times since 2003 (0.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 89, Issue 5, 1 1 2003, Pages 557-558 DD ACE gene polymorphism is associated with increased coronary artery endothelial dysfunction: the PREFACE trial. Mulder HJ, van Geel PP, Schalij MJ, van Gilst WH, Zwinderman AH, Bruschke AV, PREFACE trial
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 11, Issue 5, 1 1 2003, Pages 203-209 Simultaneous measurement of right and left ventricular volume by the conductance catheter technique in the newborn lamb. Cardozo RH, de Vroomen M, van Bel F, Baan J, Steendijk P
Background: Measurement of absolute ventricular volume with the conductance catheter technique has been documented extensively for the left ventricle (LV). More recently, the same technique has been applied in studies of right ventricular (RV) performance. In the present study we performed simultaneous measurements of LV and RV volumes. Conversion of measured conductances to absolute volumes requires the assessment of slope factor alpha (α) and parallel conductance correction volume (Vc) for bot... Abstract
Cited 48 times since 2003 (2.2 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 10, Issue 3, 1 1 2003, Pages 261-266 Long-term prognosis after a normal exercise stress Tc-99m sestamibi SPECT study. Elhendy A, Schinkel A, Bax JJ, van Domburg RT, Poldermans D
Background: Patients with a normal stress technetium 99m sestamibi study were shown to have a favorable outcome at intermediate-term follow-up. However, long-term survival has not been studied. The aim of this study was to evaluate the incidence and predictors of mortality and cardiac events at long-term follow-up after a normal exercise stress sestamibi study. Methods and results We studied 218 patients (mean age, 53 +/- 10 years, 108 men) who had normal myocardial perfusion assessed by Tc-99m... Abstract
Cited 261 times since 2003 (11.8 per year) source: EuropePMC
Circulation, Volume 107, Issue 14, 14 2 2003, Pages 1848-1851 Statins are associated with a reduced incidence of perioperative mortality in patients undergoing major noncardiac vascular surgery. Poldermans D, Bax JJ, Kertai MD, Krenning B, Westerhout CM, Schinkel AF, Thomson IR, Lansberg PJ, Fleisher LA, Klein J, van Urk H, Roelandt JR, Boersma E
Background: Patients undergoing major vascular surgery are at increased risk of perioperative mortality due to underlying coronary artery disease. Inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A (statins) may reduce perioperative mortality through the improvement of lipid profile, but also through the stabilization of coronary plaques on the vascular wall. Methods and results: To evaluate the association between statin use and perioperative mortality, we performed a case-controlled study... Abstract
Cited 47 times since 2003 (2.1 per year) source: EuropePMC
The American journal of cardiology, Volume 91, Issue 7, 1 1 2003, Pages 785-789 Impact of percutaneous coronary intervention or coronary artery bypass grafting on outcome after nonfatal cardiac arrest outside the hospital. Borger van der Burg AE, Bax JJ, Boersma E, Bootsma M, van Erven L, van der Wall EE, Schalij MJ
Survivors of cardiac arrest due to ventricular arrhythmias are at risk for recurrent events. The role of revascularization in secondary prevention for survivors of cardiac arrest has been addressed in various studies with conflicting results. A total of 142 survivors of cardiac arrest with coronary artery disease were evaluated according to a standardized protocol, including 2-dimensional echocardiography, myocardial perfusion scintigraphy, coronary angiography, and electrophysiologic testing. R... Abstract
Cited 3 times since 2003 (0.1 per year) source: EuropePMC
The Lancet. Neurology, Volume 2, Issue 4, 1 1 2003, Pages 255-256 Neurally-mediated complete heart block. Taal W, van der Dussen DH, van Erven L, van Dijk JG
Cited 3 times since 2003 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 19, Issue 2, 1 1 2003, Pages 137-140 Evaluation of myocardial viability in chronic ischemic cardiomyopathy. Bax JJ, van der Wall EE
Cited 11 times since 2003 (0.5 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 23, Issue 4, 1 1 2003, Pages 609-613 MRI evaluation of left ventricular function in anterior LV aneurysms before and after surgical resection. Versteegh MI, Lamb HJ, Bax JJ, Curiel FB, van der Wall EE, de Roos A, Dion RA
Objectives: Whether resection of a left ventricular (LV) aneurysm leads to improved global LV function remains controversial. Echo-planar magnetic resonance imaging (MRI) is a sensitive tool to detect changes in LV function. Therefore, the purpose of the present study was to monitor changes in global LV function and anatomy following LV aneurysm resection using MRI. Methods: The present study includes 12 patients with an anterior LV aneurysm. Echo-planar MRI evaluation of LV function was perform... Abstract
Cited 46 times since 2003 (2.1 per year) source: EuropePMC
Diabetes care, Volume 26, Issue 4, 1 1 2003, Pages 1074-1078 Prognostic value of dobutamine stress echocardiography in patients with diabetes. Sozzi FB, Elhendy A, Roelandt JR, van Domburg RT, Schinkel AF, Vourvouri EC, Bax JJ, De Sutter J, Borghetti A, Poldermans D
Objective: The aim of this study was to assess the incremental value of dobutamine stress echocardiography (DSE) for the risk stratification of diabetic patients who are unable to perform an adequate exercise stress test. Exercise capacity is frequently impaired in patients with diabetes. The role of pharmacologic stress echocardiography in the risk stratification of diabetic patients has not been well defined. Research design and methods: We studied 396 diabetic patients (mean age 61 +/- 11 yea... Abstract
Cited 15 times since 2003 (0.7 per year) source: EuropePMC
Allergy, Volume 58, Issue 4, 1 1 2003, Pages 300-305 Similar levels of nitric oxide in exhaled air in non-asthmatic rhinitis and asthma after bronchial allergen challenge. Lopuhaä CE, Koopmans JG, Jansen HM, van der Zee JS
Background: Nitric oxide in exhaled air (eNO) is elevated in allergic asthma compared with healthy subjects and has been proposed as a marker of bronchial inflammation. However, eNO is elevated to a lesser extent in allergic non-asthmatic rhinitis as well. Considering the distinctive clinical appearances of both allergic diseases, differences in eNO are expected to persist after allergen exposure. The aim of the study was to compare allergen-induced changes in eNO in house dust mite sensitized p... Abstract
Cited 1 times since 2003 (0 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 147, Issue 15, 1 1 2003, Pages 708-714 [Risk of ventricular fibrillation in patients with Wolff-Parkinson White syndrome]. Bootsma M, van der Wall EE, Schalij MJ
A 16-year-old boy suddenly fell off his stool, a 26-year-old man had persistent palpitations and a 29-year-old man was reanimated without an incriminating anamnesis. The diagnosis 'Wolff-Parkinson-White(WPW)-syndrome' was made in all three cases. The boy died as a result of postanoxic neurological injury; in the two men, further cardiac rhythm disturbances were prevented by interrupting the accessory atrioventricular connection via radiofrequency catheter ablation. In ECG databases, a... Abstract
Cited 1 times since 2003 (0 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 11, Issue 4, 1 1 2003, Pages 154-158 The impact of an implantable cardioverter defibrillator: the Leiden follow-up study of ICD patients and their partners. de Groot NM, Bootsma M, van der Wall EE, Schalij MJ
Objectives: The goal of this study was to evaluate 1) the presence of psychosocial problems in both ICD patients and their partners, and 2) the relation between psychosocial problems and various clinical variables. Methods: Questionnaires were sent to 219 ICD patients and their partners. Results: Sixty-eight percent of the ICD patients, 122 (81%) male, aged 59±12 years, and 62% of their partners, 28 (21%) male, aged 58±11 years, returned the questionnaires. Anxiety, depression or nervousness was... Abstract
Cited 20 times since 2003 (0.9 per year) source: EuropePMC
Annals of vascular surgery, Volume 17, Issue 2, 6 1 2003, Pages 198-202 Complication registration in patients after peripheral arterial bypass surgery. Schepers A, Klinkert P, Vrancken Peeters MP, Breslau PJ
The objective of this study was to describe the kinds of complications and their incidence after peripheral vascular surgery of the lower limb, coding for causes and effect on the patient. In this prospective study, a standardized complication registration system was used at the Red Cross Hospital, The Hague. All patients (n = 373) receiving an infrainguinal bypass graft during the period January 1, 1996 to December 31, 1999 were included. All postoperative complications occurring during admissi... Abstract
Cited 2 times since 2003 (0.1 per year) source: EuropePMC
Anticancer research, Volume 23, Issue 2C, 1 1 2003, Pages 1811-1823 Tumor necrosis factor and isolated hepatic perfusion: from preclinical tumor models to clinical studies. de Vries MR, ten Hagen TL, Marinelli AW, Eggermont AM
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 11, Issue 3, 1 1 2003, Pages 107-108 Quality of life in adults with congenital heart disease. Vliegen HW
Cited 31 times since 2003 (1.4 per year) source: EuropePMC
Annals of human genetics, Volume 67, Issue Pt 2, 1 1 2003, Pages 175-184 Estimation of multilocus haplotype effects using weighted penalised log-likelihood: analysis of five sequence variations at the cholesteryl ester transfer protein gene locus. Tanck MW, Klerkx AH, Jukema JW, De Knijff P, Kastelein JJ, Zwinderman AH
Direct analyses of haplotype effects can be used to identify those specific combinations of alleles that are associated with a specific phenotype. We introduce a method for direct haplotype analysis that solves two problems that arise when haplotypes are analysed in populations of unrelated subjects. Instead of assigning a single, most likely, haplotype pair to multiple heterozygous subjects, all haplotype pairs compatible with their genotype were determined and the posterior probabilities of th... Abstract
Cited 39 times since 2003 (1.8 per year) source: EuropePMC
Circulation, Volume 107, Issue 11, 1 1 2003, Pages 1502-1508 Value of magnetic resonance imaging for the noninvasive detection of stenosis in coronary artery bypass grafts and recipient coronary arteries. Langerak SE, Vliegen HW, Jukema JW, Kunz P, Zwinderman AH, Lamb HJ, van der Wall EE, de Roos A
Background: Magnetic resonance imaging (MRI) is a potential noninvasive diagnostic tool to detect coronary artery bypass graft stenosis, but its value in clinical practice remains to be established. We investigated the value of MRI in detecting stenotic grafts, including recipient vessels. Methods and results: We screened for inclusion 173 consecutive patients who were scheduled for coronary angiography because of recurrent chest pain after coronary artery bypass grafting (CABG). We studied 69 e... Abstract
Cited 10 times since 2003 (0.5 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 125, Issue 3, 1 1 2003, Pages 481-490 Effects of acute left ventricular unloading on right ventricular function in normal and chronic right ventricular pressure-overloaded lambs. Leeuwenburgh BP, Helbing WA, Steendijk P, Schoof PH, Baan J
Objective: Right ventricular pressure overload occurs in several types of (congenital) heart disease, as well as in pulmonary disease. Clinical outcome in some of these patient groups might in part be related to left ventricular loading conditions. The effects of left ventricular unloading on the function of the hypertrophic right ventricle have not been studied. We aimed to study the effects of left ventricular unloading on right ventricular hemodynamics and contractility in an animal model of... Abstract