6125 results
Cited 1 times since 2022 (0.4 per year)
source: EuropePMC
Journal of oral & maxillofacial research,
Volume 13, Issue 3, 1 1 2022, Pages e2
The Radiological Evaluation of Mandibular Canal Related Variables in Mandibular Third Molar Region: a Retrospective Multicenter Study.
Yilmaz D, Ataman-Duruel ET, Beycioğlu Z, Goyushov S, Çimen T, Duruel O, Tözüm TF
Objectives: The aim of this retrospective study was to investigate anatomical structure of mandibular canal and the factors those increase the possibility of inferior alveolar nerve damage in mandibular third molar region of Turkish population. Material and methods: Overall 320 participants with 436 mandibular third molars were included from four different study centers. Following variables were measured: type and depth of third molar impaction, position of mandibular canal in relation to third...
Abstract
Cited 8 times since 2022 (3 per year)
source: EuropePMC
Cardiovascular research,
Volume 118, Issue 10, 1 1 2022, Pages 2293-2303
Optical ventricular cardioversion by local optogenetic targeting and LED implantation in a cardiomyopathic rat model.
Nyns ECA, Jin T, Fontes MS, van den Heuvel T, Portero V, Ramsey C, Bart CI, Zeppenfeld K, Zeppenfeld K, Schalij MJ, van Brakel TJ, Ramkisoensing AA, Zhang G, Poelma RH, Ördög B, de Vries AAF, Pijnappels DA
Aims: Ventricular tachyarrhythmias (VTs) are common in the pathologically remodelled heart. These arrhythmias can be lethal, necessitating acute treatment like electrical cardioversion to restore normal rhythm. Recently, it has been proposed that cardioversion may also be realized via optically controlled generation of bioelectricity by the arrhythmic heart itself through optogenetics and therefore without the need of traumatizing high-voltage shocks. However, crucial mechanistic and translation...
Abstract
Cited 2 times since 2022 (0.8 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 8, 1 1 2022, Pages 1090-1097
Association between computed tomography-derived tricuspid annular dimensions and prognosis: insights from whole-beat computed tomography assessment.
Hirasawa K, Fortuni F, van Rosendael PJ, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Tricuspid regurgitation (TR) has been associated with outcome in patients treated with transcatheter aortic valve implantation (TAVI). Tricuspid annulus (TA) dimensions are associated with TR. However, the TA is highly dynamic during the cardiac cycle, and the interaction between the TA dimensions, TR, and patient prognosis has never been evaluated. This study aimed to characterize the dynamics of the TA along with the cardiac cycle and its association with prognosis in patients undergoing...
Abstract
JACC. Cardiovascular interventions,
Volume 15, Issue 14, 1 1 2022, Pages 1491
Reply: Could Left Atrial Function Modify Outcomes After Transcatheter Edge-to-Edge Repair of the Mitral Valve?
Yoon SH, Siegel RJ, Bax JJ, Makkar RR
Abstract
Cited 5 times since 2022 (1.9 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 62, Issue 2, 1 1 2022, Pages ezac290
Staging right heart failure in patients with tricuspid regurgitation undergoing tricuspid surgery.
Galloo X, Stassen J, Butcher SC, Meucci MC, Dietz MF, Mertens BJA, Prihadi EA, van der Bijl P, Ajmone Marsan N, Braun J, Bax JJ, Delgado V
Objectives: This study evaluated the prognostic value of staging right heart failure in patients with significant tricuspid regurgitation (TR) undergoing tricuspid valve (TV) surgery. Methods: Patients with significant TR who underwent TV surgery were divided into 4 right heart failure stages according to the presence of right ventricular (RV) dysfunction and clinical signs of right heart failure: stage 1 was defined as no RV dysfunction and no signs of right heart failure; stage 2 indicated RV...
Abstract
Cited 14 times since 2022 (5.3 per year)
source: EuropePMC
Annals of cardiothoracic surgery,
Volume 11, Issue 4, 1 1 2022, Pages 380-388
Normal and abnormal development of the aortic valve and ascending aortic wall: a comprehensive overview of the embryology and pathology of the bicuspid aortic valve.
Grewal N, Gittenberger-de Groot AC, Lindeman JH, Klautz A, Driessen A, Klautz RJM, Poelmann RE
A bicuspid aortic valve (BAV) is the most prevalent congenital cardiac anomaly, in which the valve has only two leaflets, instead of the normal three. Patients with a BAV have an increased risk of aneurysm formation and the development of an aortic dissection. Vascular smooth muscle cells in both the non- and dilated aortic wall are characterized by a maturation defect in all BAV patients, as compared to patients with a tricuspid aortic valve, which can contribute to inherent developmental susce...
Abstract
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 8, 1 1 2022, Pages e301-e302
Discussion forum: it is time to assess left ventricular segmental remodelling in aortic stenosis.
Stassen J, Bax JJ
Abstract
Cited 36 times since 2022 (13.5 per year)
source: EuropePMC
Circulation,
Volume 146, Issue 9, 30 5 2022, Pages 657-672
Apolipoprotein B, Residual Cardiovascular Risk After Acute Coronary Syndrome, and Effects of Alirocumab.
Hagström E, Steg PG, Szarek M, Bhatt DL, Bittner VA, Danchin N, Diaz R, Goodman SG, Harrington RA, Jukema JW, Liberopoulos E, Marx N, McGinniss J, Manvelian G, Pordy R, Scemama M, White HD, Zeiher AM, Schwartz GG, ODYSSEY OUTCOMES Investigators
Background: Apolipoprotein B (apoB) provides an integrated measure of atherogenic risk. Whether apoB levels and apoB lowering hold incremental predictive information on residual risk after acute coronary syndrome beyond that provided by low-density lipoprotein cholesterol is uncertain. Methods: The ODYSSEY OUTCOMES trial (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) compared the proprotein convertase subtilisin/kexin type 9 inhibitor al...
Abstract
Cited 1 times since 2022 (0.4 per year)
source: EuropePMC
Revista espanola de cardiologia (English ed.),
Volume 76, Issue 1, 24 4 2022, Pages 2-3
Fusion imaging in congenital heart disease: just a pretty picture or a new tool to improve patient management?
Regeer MV, Ajmone Marsan N
Abstract
Frontiers in physiology,
Volume 13, 23 4 2022, Pages 909870
Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.
Schillemans T, Tragante V, Maitusong B, Gigante B, Cresci S, Laguzzi F, Vikström M, Richards M, Pilbrow A, Cameron V, Foco L, Doughty RN, Kuukasjärvi P, Allayee H, Hartiala JA, Tang WHW, Lyytikäinen LP, Nikus K, Laurikka JO, Srinivasan S, Mordi IR, Trompet S, Kraaijeveld A, van Setten J, Gijsberts CM, Maitland-van der Zee AH, Saely CH, Gong Y, Johnson JA, Cooper-DeHoff RM, Pepine CJ, Casu G, Leiherer A, Drexel H, Horne BD, van der Laan SW, Marziliano N, Hazen SL, Sinisalo J, Kähönen M, Lehtimäki T, Lang CC, Burkhardt R, Scholz M, Jukema JW, Eriksson N, Åkerblom A, James S, Held C, Hagström E, Spertus JA, Algra A, de Faire U, Åkesson A, Asselbergs FW, Patel RS, Leander K
Background: The knowledge of factors influencing disease progression in patients with established coronary heart disease (CHD) is still relatively limited. One potential pathway is related to peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PPARGC1A), a transcription factor linked to energy metabolism which may play a role in the heart function. Thus, its associations with subsequent CHD events remain unclear. We aimed to investigate the effect of three different SNPs in the...
Abstract
Cited 3 times since 2022 (1.1 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 11, Issue 13, 22 4 2022, Pages e024924
Arrhythmia Monitoring and Outcomes in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium.
Bressi E, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TM, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J, Cardiac Sarcoidosis Consortium *
Abstract
Cited 1 times since 2022 (0.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 30, Issue 1, 20 3 2022, Pages 251-253
Using a deep learning algorithm to score coronary artery calcium in myocardial perfusion imaging: A real opportunity or just a new hype?
Stassen J, van der Bijl P, Bax JJ
Abstract
Cited 19 times since 2022 (7 per year)
source: EuropePMC
Science (New York, N.Y.),
Volume 376, Issue 6599, 17 3 2022, Pages eabf9088
Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.
O'Neill AC, Uzbas F, Antognolli G, Merino F, Draganova K, Jäck A, Zhang S, Pedini G, Schessner JP, Cramer K, Schepers A, Metzger F, Esgleas M, Smialowski P, Guerrini R, Falk S, Feederle R, Freytag S, Wang Z, Bahlo M, Jungmann R, Bagni C, Borner GHH, Robertson SP, Hauck SM, Götz M
The centrosome provides an intracellular anchor for the cytoskeleton, regulating cell division, cell migration, and cilia formation. We used spatial proteomics to elucidate protein interaction networks at the centrosome of human induced pluripotent stem cell-derived neural stem cells (NSCs) and neurons. Centrosome-associated proteins were largely cell type-specific, with protein hubs involved in RNA dynamics. Analysis of neurodevelopmental disease cohorts identified a significant overrepresentat...
Abstract
Cited 13 times since 2022 (4.8 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 15, Issue 10, 15 3 2022, Pages 1760-1767
Association Between Changes in Perivascular Adipose Tissue Density and Plaque Progression.
Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Kitslaar PH, Reiber JHC, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
Background: The association between the change in vessel inflammation, as quantified by perivascular adipose tissue (PVAT) density, and the progression of coronary atherosclerosis remains to be determined. Objectives: The purpose of this study was to explore the association between the change in PVAT density and the progression of total and compositional plaque volume (PV). Methods: Patients were selected from a prospective multinational registry. Patients who underwent serial coronary computed...
Abstract
Cited 5 times since 2022 (1.8 per year)
source: EuropePMC
International journal of cardiology,
Volume 363, 15 3 2022, Pages 87-93
Left atrioventricular coupling index in hypertrophic cardiomyopathy and risk of new-onset atrial fibrillation.
Meucci MC, Fortuni F, Galloo X, Bootsma M, Crea F, Bax JJ, Marsan NA, Delgado V
Backgrounds: This study aimed to investigate the association between left atrioventricular coupling index (LACI) and the occurrence of atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). Methods: A total of 373 patients with HCM and no history of AF were evaluated by transthoracic echocardiography. LACI was defined by the ratio of left atrial (LA) end-diastolic volume divided by left ventricular (LV) end-diastolic volume. The cut-off value for LACI (≥40%) to identify LA-...
Abstract
Cited 2 times since 2022 (0.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 177, 9 2 2022, Pages 90-99
Prognostic Implications of Change in Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Implantation.
Kuneman JH, Butcher SC, Singh GK, Wang X, Hirasawa K, van der Kley F, Leon MB, Knuuti J, Pibarot P, Ajmone Marsan N, Delgado V, Bax JJ
Reduced left ventricular (LV) systolic function is associated with worse prognosis in patients with severe aortic stenosis (AS) treated with transcatheter aortic valve implantation (TAVI). We aimed to examine the changes in left ventricular ejection fraction (LVEF) after TAVI among patients with varying baseline LVEF. Moreover, variables associated with lack of LVEF improvement were identified and the association with long-term outcomes was investigated. A total of 560 patients (age 80 ± 7 years...
Abstract
Cited 16 times since 2022 (5.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 177, 9 2 2022, Pages 151-161
Right Ventricular Myocardial Work Characterization in Patients With Pulmonary Hypertension and Relation to Invasive Hemodynamic Parameters and Outcomes.
Butcher SC, Feloukidis C, Kamperidis V, Yedidya I, Stassen J, Fortuni F, Vrana E, Mouratoglou SA, Boutou A, Giannakoulas G, Playford D, Ajmone Marsan N, Bax JJ, Delgado V
Noninvasive evaluation of indexes of right ventricular (RV) myocardial work (RVMW) derived from RV pressure-strain loops may provide novel insights into RV function in precapillary pulmonary hypertension. This study was designed to evaluate the association between the indexes of RVMW and invasive parameters of right heart catheterization and all-cause mortality. Noninvasive analysis of RVMW was completed in 51 patients (mean age 58.1 ± 12.7 years, 31% men) with group I or group IV pulmonary hype...
Abstract
Cited 3 times since 2022 (1.1 per year)
source: EuropePMC
Clinical cardiology,
Volume 45, Issue 8, 8 2 2022, Pages 873-881
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease.
Won KB, Park HB, Heo R, Lee BK, Lin FY, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Gonçalves PA, Leipsic JA, Lee SE, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Berman DS, Narula J, Bax JJ, Min JK, Chang HJ
Background: Atherosclerosis-related adverse events are commonly observed even in conditions with low cardiovascular (CV) risk. Longitudinal data regarding the association of normal systolic blood pressure maintenance (SBPmaintain ) with coronary plaque volume changes (PVC) has been limited in adults without traditional CV disease. Hypothesis: Normal SBPmaintain is important to attenuate coronary atherosclerosis progression in adults without baseline CV disease. Methods: We analyzed 95 adults (56...
Abstract
Cited 1 times since 2022 (0.4 per year)
source: EuropePMC
Structural heart : the journal of the Heart Team,
Volume 6, Issue 3, 8 2 2022, Pages 100042
Sex-Related Differences in Medically Treated Moderate Aortic Stenosis.
Stassen J, Pio SM, Ewe SH, Amanullah MR, Hirasawa K, Butcher SC, Singh GK, Sin KYK, Ding ZP, Chew NWS, Sia CH, Kong WKF, Poh KK, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Bax JJ
Background: Recent data showed poor long-term survival in patients with moderate AS. Although sex differences in left ventricular (LV) remodeling and outcome are well described in severe AS, it has not been evaluated in moderate AS. Methods: In this retrospective, multicenter study, patients with a first diagnosis of moderate AS diagnosed between 2001 and 2019 were identified. Clinical and echocardiographic parameters were recorded at baseline and compared between men and women. Patients were fo...
Abstract
Cited 18 times since 2022 (6.6 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 7, 1 1 2022, Pages 885-897
The dysfunctional right ventricle: the importance of multi-modality imaging.
Surkova E, Cosyns B, Gerber B, Gimelli A, La Gerche A, Ajmone Marsan N
Assessment of right ventricular (RV) function is crucial for the evaluation of the dyspnoeic patient and/or with systemic venous congestion and provides powerful prognostic insights. It can be performed using different imaging modalities including standard and advanced echocardiographic techniques, cardiac magnetic resonance imaging, computed tomography, and radionuclide techniques, which should be used in a complementary fashion. Each modality has strengths and weaknesses based on which the cho...
Abstract
