Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6128 results
Cited 79 times since 2019 (13.1 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 12, Issue 3, 1 1 2019, Pages 491-499 Morphologic Types of Tricuspid Regurgitation: Characteristics and Prognostic Implications. Prihadi EA, Delgado V, Leon MB, Enriquez-Sarano M, Topilsky Y, Bax JJ
Tricuspid regurgitation (TR) is classified according to different morphologic types based on the underlying mechanisms: primary, secondary, and isolated TR. Primary TR is caused by an anatomical abnormality of the tricuspid valve apparatus. Secondary TR is caused by dilation of the tricuspid valve annulus, related to right ventricular (RV), or right atrial remodeling and increased RV pressures (often secondary to left-sided heart disease). Isolated TR can exist in patients without increased RV p... Abstract
European heart journal, Volume 40, Issue 11, 1 1 2019, Pages 867 Dr Shahbudin H. Rahimtoola: the mentor. Bax JJ
Cited 3 times since 2019 (0.5 per year) source: EuropePMC
Advances in physiology education, Volume 43, Issue 1, 1 1 2019, Pages 7-14 Informing the uninformed: a multitier approach to uncover students' misconceptions on cardiovascular physiology. Versteeg M, Wijnen-Meijer M, Steendijk P
Misconceptions about physiology are a major threat to accurate scientific and clinical reasoning in medical education. Awareness is often mentioned as a prerequisite to achieve conceptual understanding; however, students are frequently unaware of their incorrect understanding. We explored the multitier approach as a tool to obtain insight into students' awareness and misconceptions regarding cardiovascular physiology. Biomedical sciences students ( N = 81) participated in a diagnostic multi... Abstract
Cited 10 times since 2019 (1.7 per year) source: EuropePMC
Lancet (London, England), Volume 393, Issue 10175, 1 1 2019, Pages 1056-1070 Multimodality imaging in ischaemic heart failure. Bax JJ, Di Carli M, Narula J, Delgado V
In heart failure, extensive evaluation with modern non-invasive imaging modalities is needed to assess causes, pathophysiology, and haemodynamics, to determine prognosis and consider therapeutic options. This systematic evaluation includes a stepwise assessment of left ventricular size and function, the presence and severity of coronary artery disease, mitral regurgitation, pulmonary hypertension, right ventricular dilation and dysfunction, and tricuspid regurgitation. Based on this imaging-deri... Abstract
Cited 11 times since 2019 (1.8 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 27, Issue 3, 1 1 2019, Pages 127-133 Frailty score for elderly patients is associated with short-term clinical outcomes in patients with ST-segment elevated myocardial infarction treated with primary percutaneous coronary intervention. Hermans MPJ, Eindhoven DC, van Winden LAM, de Grooth GJ, Blauw GJ, Muller M, Schalij MJ
Objective: Consistent with the aging population in the Western world, there is a growing number of elderly patients with ST-segment elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention (PCI) is the recommended reperfusion strategy in elderly patients; risk models to determine which of these patients are prone to have poor clinical outcomes are, however, essential. The purpose of this study was to assess the association between frailty and short-term mortality and P... Abstract
Cited 66 times since 2019 (11 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 12, Issue 3, 1 1 2019, Pages e008666 Prognostic Implications of Right Ventricular Free Wall Longitudinal Strain in Patients With Significant Functional Tricuspid Regurgitation. Prihadi EA, van der Bijl P, Dietz M, Abou R, Vollema EM, Marsan NA, Delgado V, Bax JJ
Background In patients with significant functional tricuspid regurgitation, timely detection of right ventricular (RV) dysfunction with conventional 2-dimensional echocardiography is challenging, whereas speckle-tracking echocardiography RV free wall longitudinal strain has been proposed as better prognosticator. We evaluated the prevalence and prognostic value of impaired RV free wall longitudinal strain in patients with significant functional tricuspid regurgitation, in comparison with tricusp... Abstract
Cited 279 times since 2019 (46.4 per year) source: EuropePMC
Circulation, Volume 139, Issue 12, 1 1 2019, Pages 1483-1492 Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk. O'Donoghue ML, Fazio S, Giugliano RP, Stroes ESG, Kanevsky E, Gouni-Berthold I, Im K, Lira Pineda A, Wasserman SM, Češka R, Ezhov MV, Jukema JW, Jensen HK, Tokgözoğlu SL, Mach F, Huber K, Sever PS, Keech AC, Pedersen TR, Sabatine MS
Background: Lipoprotein(a) [Lp(a)] may play a causal role in atherosclerosis. PCSK9 (proprotein convertase subtilisin/kexin 9) inhibitors have been shown to significantly reduce plasma Lp(a) concentration. However, the relationship between Lp(a) levels, PCSK9 inhibition, and cardiovascular risk reduction remains undefined. Methods: Lp(a) was measured in 25 096 patients in the FOURIER trial (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk), a randomiz... Abstract
Cited 42 times since 2019 (7 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 21, Issue 3, 1 1 2019, Pages 366-376 Mechanisms of sex differences in atrial fibrillation: role of hormones and differences in electrophysiology, structure, function, and remodelling. Odening KE, Deiß S, Dilling-Boer D, Didenko M, Eriksson U, Nedios S, Ng FS, Roca Luque I, Sanchez Borque P, Vernooy K, Wijnmaalen AP, Yorgun H
Atrial fibrillation (AF) is the clinically most prevalent rhythm disorder with large impact on quality of life and increased risk for hospitalizations and mortality in both men and women. In recent years, knowledge regarding epidemiology, risk factors, and patho-physiological mechanisms of AF has greatly increased. Sex differences have been identified in the prevalence, clinical presentation, associated comorbidities, and therapy outcomes of AF. Although it is known that age-related prevalence o... Abstract
Cited 9 times since 2019 (1.5 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 21, Issue 3, 1 1 2019, Pages 383-403 Advancement in cardiac imaging for treatment of ventricular arrhythmias in structural heart disease. Sramko M, Hoogendoorn JC, Glashan CA, Zeppenfeld K
Over the last decades, substrate-based approaches to ventricular tachycardia (VT) ablation have evolved into an important therapeutic option for patients with various structural heart diseases (SHD) and unmappable VT. The well-recognized limitations of conventional electroanatomical mapping (EAM) to delineate the complex 3D architecture of scar, and the potential capability of advanced cardiac imaging technologies to provide adjunctive information, have stimulated electrophysiologists to evaluat... Abstract
Cited 19 times since 2019 (3.2 per year) source: EuropePMC
Journal of the American Heart Association, Volume 8, Issue 6, 1 1 2019, Pages e007201 Coronary Calcium Characteristics as Predictors of Major Adverse Cardiac Events in Symptomatic Patients: Insights From the CORE 320 Multinational Study. Lo-Kioeng-Shioe MS, Vavere AL, Arbab-Zadeh A, Schuijf JD, Rochitte CE, Chen MY, Rief M, Kofoed KF, Clouse ME, Scholte AJ, Miller JM, Betoko A, Blaha MJ, Cox C, Deckers JW, Lima JAC
Background The predictive value of coronary artery calcium ( CAC ) has been widely studied; however, little is known about specific characteristics of CAC that are most predictive. We aimed to determine the independent associations of Agatston score, CAC volume, CAC area, CAC mass, and CAC density score with major adverse cardiac events in patients with suspected coronary artery disease. Methods and Results A total of 379 symptomatic participants, aged 45 to 85 years, referred for invasive coron... Abstract
Cited 12 times since 2019 (2 per year) source: EuropePMC
The Journal of rheumatology, Volume 46, Issue 4, 1 1 2019, Pages 405-415 Progression of Left Ventricular Myocardial Dysfunction in Systemic Sclerosis: A Speckle-tracking Strain Echocardiography Study. van Wijngaarden SE, Ben Said-Bouyeri S, Ninaber MK, Huizinga TWJ, Schalij MJ, Bax JJ, Delgado V, de Vries-Bouwstra JK, Marsan NA
Objective: Cardiac involvement is a main cause of mortality in systemic sclerosis (SSc). Its detection remains challenging using conventional echocardiography and little is known about its potential progression. This study assessed changes in cardiac performance over time in a prospective cohort of patients with SSc, including echocardiographic speckle-tracking strain analysis. Methods: The study included 234 patients with SSc [196 women, age 52 ± 14 yrs, 165 limited SSc, time since diagnosis 5.... Abstract
Cited 26 times since 2019 (4.3 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 5, Issue 4, 27 4 2019, Pages 480-489 Entropy as a Novel Measure of Myocardial Tissue Heterogeneity for Prediction of Ventricular Arrhythmias and Mortality in Post-Infarct Patients. Androulakis AFA, Zeppenfeld K, Paiman EHM, Piers SRD, Wijnmaalen AP, Siebelink HJ, Sramko M, Lamb HJ, van der Geest RJ, de Riva M, Tao Q
Objectives: This study proposed entropy as a new late gadolinium enhanced cardiac magnetic resonance-derived parameter to evaluate tissue inhomogeneity, independent of signal intensity thresholds. This study hypothesized that entropy within the scar is associated with ventricular arrhythmias (VAs), whereas entropy of the entire left ventricular (LV) myocardium is associated with mortality. Background: In patients after myocardial infarction, the heterogeneity of fibrosis determines the substrate... Abstract
Cited 4 times since 2019 (0.7 per year) source: EuropePMC
The American journal of cardiology, Volume 123, Issue 10, 22 4 2019, Pages 1722-1728 Comparison of Diagnostic Performance of Quantitative Flow Ratio in Patients With Versus Without Diabetes Mellitus. Smit JM, El Mahdiui M, van Rosendael AR, Jukema JW, Koning G, Reiber JHC, Bax JJ, Scholte AJ
Quantitative flow ratio (QFR) is a novel technique to calculate fractional flow reserve (FFR), without hyperemia induction or a pressure wire, and has not yet been validated in patients with diabetes mellitus (DM), who are at increased risk of coronary microvascular dysfunction. The purpose of our study was to compare the diagnostic performance of QFR in diabetic and nondiabetic patients. Patients who underwent invasive coronary angiography and subsequent invasive FFR measurement within 6 months... Abstract
Cited 7 times since 2019 (1.2 per year) source: EuropePMC
Journal of diabetes research, Volume 2019, 21 3 2019, Pages 9727952 The APOE<sup>∗</sup>3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis. Pouwer MG, Heinonen SE, Behrendt M, Andréasson AC, van Koppen A, Menke AL, Pieterman EJ, van den Hoek AM, Jukema JW, Leighton B, Jönsson-Rylander AC, Princen HMG
Background: There is a lack of predictive preclinical animal models combining atherosclerosis and type 2 diabetes. APOE∗3-Leiden (E3L) mice are a well-established model for diet-induced hyperlipidemia and atherosclerosis, and glucokinase+/- (GK+/-) mice are a translatable disease model for glucose control in type 2 diabetes. The respective mice respond similarly to lipid-lowering and antidiabetic drugs as humans. The objective of this study was to evaluate/characterize the APOE∗3-Leiden.glucokin... Abstract
Cited 14 times since 2019 (2.3 per year) source: Scopus
The Canadian journal of cardiology, Volume 35, Issue 6, 21 3 2019, Pages 796.e9-796.e11 Percutaneous Decannulation of Femoral Venoarterial ECMO Cannulas Using MANTA Vascular Closure Device. Montero-Cabezas JM, van der Meer RW, van der Kley F, Elzo Kraemer CV, López Matta JE, Schalij MJ, de Weger A
Extracorporeal membrane oxygenation (ECMO) has been increasingly used in the treatment of refractory cardiac arrest and postarrest cardiogenic shock. We propose a technique for percutaneous decannulation of femoral venoarterial ECMO cannulas by using the MANTA vascular closure device, designed to close large-bore arteriotomies. This technique significantly simplifies the decannulation and might diminish the potential complications caused by the standard surgical removal. Abstract
Cited 7 times since 2019 (1.2 per year) source: EuropePMC
Expert review of cardiovascular therapy, Volume 17, Issue 3, 19 3 2019, Pages 185-192 eHealth to improve patient outcome in rehabilitating myocardial infarction patients. Verburg A, Selder JL, Schalij MJ, Schuuring MJ, Treskes RW
Introduction: Cardiac rehabilitation is aimed at risk factor modification and improving quality of life. eHealth has a couple of potential benefits to improve this aim. The primary purpose of this review is to summarize available literature for eHealth strategies that have been investigated in randomized controlled trials in post-myocardial infarction (MI) patients. The second purpose of this review is to investigate the clinical effectiveness in post-MI patients. Areas covered: The literature w... Abstract
Journal of orthopaedic surgery and research, Volume 14, Issue 1, 14 2 2019, Pages 49 Continuous-flow cryocompression therapy penetrates to bone level in hip fracture patients in a numerical simulation. Leegwater NC, van der Meer SM, Sierevelt IN, Spruijt H, Nolte PA
Background: The aim of this study was to define deep tissue temperature during cryotherapy in postoperative hip fracture patients, by using measured skin temperature as input parameter for a simple numerical model. Second, an association was investigated between pain and tissue temperature distribution, to assess cryotherapy-induced analgesia of soft tissue-derived pain. Methods: Data from 35 participants in an ongoing trial was used. In three subjects who consented on optional measurements, ski... Abstract
Cited 2 times since 2019 (0.3 per year) source: EuropePMC
Cardiology and therapy, Volume 8, Issue 1, 13 2 2019, Pages 55-67 Plasma LDL-Cholesterol Level at Admission is Independently Associated with Infarct Size in Patients with ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention. Bodde MC, Hermans MPJ, Wolterbeek R, Cobbaert CM, van der Laarse A, Schalij MJ, Jukema JW
Introduction: Hypercholesterolemia is a well-known risk factor for developing atherosclerosis and subsequently for the risk of a myocardial infarction (MI). Moreover, it might also be related to the extent of damaged myocardium in the event of a MI. The aim of this study was to evaluate the association of baseline low density lipoprotein-cholesterol (LDL-c) level with infarct size in patients with ST-segment elevation myocardial infarction (STEMI) after primary percutaneously coronary interventi... Abstract
Stem cells (Dayton, Ohio), Volume 37, Issue 5, 13 2 2019, Pages E1 Young Versus Adult: Finding Clues to Unravel the Increased Regenerative Ability of Stem Cells from Young Donors. Ramkisoensing AA
Cited 8 times since 2019 (1.3 per year) source: EuropePMC
The American journal of cardiology, Volume 123, Issue 9, 10 2 2019, Pages 1435-1442 The Predictive Value of Coronary Artery Calcium Scoring for Major Adverse Cardiac Events According to Renal Function (from the Coronary Computed Tomography Angiography Evaluation for Clinical Outcomes: An International Multicenter [CONFIRM] Registry). Lee JH, Rizvi A, Hartaigh BÓ, Han D, Park MW, Roudsari HM, Stuijfzand WJ, Gransar H, Lu Y, Callister TQ, Berman DS, DeLago A, Hadamitzky M, Hausleiter J, Al-Mallah MH, Budoff MJ, Kaufmann PA, Raff GL, Chinnaiyan K, Cademartiri F, Maffei E, Villines TC, Kim YJ, Leipsic J, Feuchtner G, Pontone G, Andreini D, Marques H, de Araújo Gonçalves P, Rubinshtein R, Achenbach S, Shaw LJ, Chow BJW, Cury RC, Bax JJ, Chang HJ, Jones EC, Lin FY, Min JK, Peña JM
The prognostic performance of coronary artery calcium score (CACS) for predicting adverse outcomes in patients with decreased renal function remains unclear. We aimed to examine whether CACS improves risk stratification by demonstrating incremental value beyond a traditional risk score according to renal function status. 9,563 individuals without known coronary artery disease were enrolled. Estimated glomerular filtration rate (eGFR, ml/min/1.73 m2) was ascertained using the modified Modificatio... Abstract