Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6205 results
Cited 16 times since 2017 (1.9 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 103, Issue 6, 24 4 2017, Pages 1976-1983 Long-Term Follow-Up After the Ross Procedure: A Single Center 22-Year Experience. Schneider AW, Putter H, Klautz RJM, Bruggemans EF, Holman ER, Bökenkamp R, Hazekamp MG
Background: The aim of this study was to analyze long-term outcomes after the Ross procedure, focusing on autograft function and risk of reoperation in time. Methods: Between February 1994 and February 2016, 154 patients underwent the Ross (n = 105) and Ross-Konno (n = 49) procedure at our institution and were included in this study. Data were collected retrospectively from patients' medical records or through telephone contact. Competing risks analyses were performed to determine incidence... Abstract
Cited 24 times since 2017 (2.9 per year) source: EuropePMC
RNA biology, Volume 14, Issue 9, 23 4 2017, Pages 1089-1098 Antibodies specific for nucleic acid modifications. Feederle R, Schepers A
Nucleotide modifications constitute marks in RNA and DNA that contribute to gene regulation, development and other cellular processes. The understanding of their intricate molecular roles has been hampered by the high number of different modifications, the lack of effective methods and tools for their detection and quantification as well as by their complex structure-function relationship. The recent development of RNA and DNA immunoprecipitation followed by high-throughput sequencing (RIP- and... Abstract
Cited 12 times since 2017 (1.5 per year) source: EuropePMC
Annals of intensive care, Volume 7, Issue 1, 23 4 2017, Pages 20 Hemodynamic effects of short-term hyperoxia after coronary artery bypass grafting. Helmerhorst HJF, de Wilde RBP, Lee DH, Palmen M, Jansen JRC, van Westerloo DJ, de Jonge E
Background: Although oxygen is generally administered in a liberal manner in the perioperative setting, the effects of oxygen administration on dynamic cardiovascular parameters, filling status and cerebral perfusion have not been fully unraveled. Our aim was to study the acute hemodynamic and microcirculatory changes before, during and after arterial hyperoxia in mechanically ventilated patients after coronary artery bypass grafting (CABG) surgery. Methods: This was a single-center physiologica... Abstract
Cited 38 times since 2017 (4.6 per year) source: EuropePMC
Circulation. Cardiovascular quality and outcomes, Volume 10, Issue 2, 22 4 2017, Pages e003178 Does the Use of a Decision Aid Improve Decision Making in Prosthetic Heart Valve Selection? A Multicenter Randomized Trial. Korteland NM, Ahmed Y, Koolbergen DR, Brouwer M, de Heer F, Kluin J, Bruggemans EF, Klautz RJ, Stiggelbout AM, Bucx JJ, Roos-Hesselink JW, Polak P, Markou T, van den Broek I, Ligthart R, Bogers AJ, Takkenberg JJ
Background: A Dutch online patient decision aid to support prosthetic heart valve selection was recently developed. A multicenter randomized controlled trial was conducted to assess whether use of the patient decision aid results in optimization of shared decision making in prosthetic heart valve selection. Methods and results: In a 5-center randomized controlled trial, patients were allocated to receive either standard preoperative care (control group) or additional access to the patient decisi... Abstract
Cardiovascular revascularization medicine : including molecular interventions, Volume 18, Issue 6 Suppl 1, 20 3 2017, Pages 48-51 Microcatheters: A valuable tool in the presence of a challenging coronary anatomy in the setting of acute coronary interventions. Case report and mini review. Karalis I, Andreou C, Montero Cabezas JM, Schalij MJ
Popularity of microcatheters (MCs) is growing among interventional cardiologists, especially when complex coronary anatomy is involved. However, MCs are still considered by many as a niche tool and their value in common clinical practice and in the setting of acute coronary interventions has not been fully appreciated. This case report highlights the decisive role of MC use in the successful completion of a primary percutaneous coronary intervention. Characteristics and indications of the most c... Abstract
Cited 13 times since 2017 (1.6 per year) source: EuropePMC
Archives of cardiovascular diseases, Volume 110, Issue 5, 17 3 2017, Pages 354-362 Ventricular arrhythmias and sudden death in tetralogy of Fallot. Maury P, Sacher F, Rollin A, Mondoly P, Duparc A, Zeppenfeld K, Hascoet S, Réseau francophone de rythmologie pédiatrique et congénitale
Malignant ventricular arrhythmias and sudden cardiac death may late happen in repaired tetralogy of Fallot, although probably less frequently than previously thought, especially with the advent of new surgical techniques/management. Ventricular tachycardias are caused by reentry around the surgical scars/patches and valves. Many predictive factors have been proposed, which suffer from poor accuracy. There is currently no recommended indication for prophylactic implantable cardioverter defibrilla... Abstract
Cited 12 times since 2017 (1.4 per year) source: EuropePMC
The American journal of cardiology, Volume 119, Issue 9, 9 2 2017, Pages 1456-1462 Relation of Myocardial Contrast-Enhanced T<sub>1</sub> Mapping by Cardiac Magnetic Resonance to Left Ventricular Reverse Remodeling After Cardiac Resynchronization Therapy in Patients With Nonischemic Cardiomyopathy. Höke U, Khidir MJ, van der Geest RJ, Schalij MJ, Bax JJ, Delgado V, Ajmone Marsan N
Myocardial scar is known to be associated with limited left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). However, the impact of diffuse myocardial interstitial fibrosis, as assessed with myocardial T1 mapping cardiac magnetic resonance (CMR), has not been studied in patients with CRT. Therefore, we aimed at evaluating the association between diffuse myocardial interstitial fibrosis, in nonischemic cardiomyopathy patients, and LV reverse remodeling after CRT.... Abstract
Cited 12 times since 2017 (1.4 per year) source: EuropePMC
European journal of heart failure, Volume 19, Issue 9, 8 2 2017, Pages 1145-1151 Impact of QRS complex duration and morphology on left ventricular reverse remodelling and left ventricular function improvement after cardiac resynchronization therapy. van der Bijl P, Khidir M, Leung M, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
Aims: To evaluate the impact of the interaction of QRS duration and morphology on left ventricular (LV) reverse remodelling and LV functional improvement in heart failure (HF) patients treated with cardiac resynchronization therapy (CRT). Methods and results: From an ongoing registry of HF patients treated with CRT according to contemporary guidelines, demographic, clinical, electrocardiographic (ECG) and echocardiographic characteristics were analysed. Patients were divided according to QRS dur... Abstract
Cited 27 times since 2017 (3.2 per year) source: EuropePMC
BMC endocrine disorders, Volume 17, Issue 1, 3 1 2017, Pages 6 Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST). Stott DJ, Gussekloo J, Kearney PM, Rodondi N, Westendorp RG, Mooijaart S, Kean S, Quinn TJ, Sattar N, Hendry K, Du Puy R, Den Elzen WP, Poortvliet RK, Smit JW, Jukema JW, Dekkers OM, Blum M, Collet TH, McCarthy V, Hurley C, Byrne S, Browne J, Watt T, Bauer D, Ford I
Background: Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4). Evidence is lacking about the effect of thyroid hormone treatment. We describe the protocol of a large randomised controlled trial (RCT) of Levothyroxine treatment for SCH. Methods: Participants are community-dwelling subjects aged ≥65 years with SCH, diagnosed by elevated TSH levels (≥4.6 and ≤19.9 mU/L) o... Abstract
Cited 35 times since 2017 (4.2 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 69, Issue 5, 1 1 2017, Pages 497-507 Isolated Subepicardial Right Ventricular Outflow Tract Scar in Athletes With Ventricular Tachycardia. Venlet J, Piers SR, Jongbloed JD, Androulakis AF, Naruse Y, den Uijl DW, Kapel GF, de Riva M, van Tintelen JP, Barge-Schaapveld DQ, Schalij MJ, Zeppenfeld K
Background: High-level endurance training has been associated with right ventricular pathological remodeling and ventricular tachycardia (VT). Although overlap with arrhythmogenic right ventricular cardiomyopathy (ARVC) has been suggested, the arrhythmogenic substrate for VTs in athletes is unknown. Objectives: The goal of this study was to evaluate whether electroanatomic scar patterns related to sustained VT can distinguish exercise-induced arrhythmogenic remodeling from ARVC and post-inflamma... Abstract
Cited 17 times since 2017 (2 per year) source: EuropePMC
JACC. Cardiovascular interventions, Volume 10, Issue 4, 1 1 2017, Pages 388-390 Bioprosthetic Heart Valves, Thrombosis, Anticoagulation, and Imaging Surveillance. Bax JJ, Delgado V
Cited 26 times since 2017 (3.1 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 10, Issue 2, 1 1 2017, Pages e004614 Association Between Posterior Left Atrial Adipose Tissue Mass and Atrial Fibrillation. van Rosendael AR, Dimitriu-Leen AC, van Rosendael PJ, Leung M, Smit JM, Saraste A, Knuuti J, van der Geest RJ, van der Arend BW, van Zwet EW, Scholte AJ, Delgado V, Bax JJ
Background: Epicardial adipose tissue located close to the atrial wall can change the electric conduction of the left atrium, potentially leading to atrial fibrillation (AF). The aim of this study was to assess whether an increased atrial adipose tissue mass posterior to the left atrium is related to AF independent of demographical and cardiovascular risk factors. Methods and results: Two hundred patients with AF and 200 patients without AF who underwent computed tomographic angiography were inc... Abstract
Cited 3 times since 2017 (0.4 per year) source: EuropePMC
European heart journal, Volume 38, Issue 6, 1 1 2017, Pages 390-399 The year in cardiology 2016: imaging. Delgado V, Gaemperli O, Lombardi M, Kaufmann PA, Bax JJ
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 24, Issue 1, 1 1 2017, Pages 180-187 Multimodality imaging: Bird's eye view from The European Society of Cardiology Congress 2016 : Rome, August 27-31, 2016. Bax JJ, Delgado V, Achenbach S, Plein S, Kaufmann PA
Cited 2 times since 2017 (0.2 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 25, Issue 2, 1 1 2017, Pages 63-64 Guidance of interventions in structural heart disease; three-dimensional techniques are here to stay. Voskuil M, Sievert H, Arslan F
Cited 87 times since 2017 (10.5 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 10, Issue 2, 1 1 2017, Pages e004052 Left Atrial Size and Function in Hypertrophic Cardiomyopathy Patients and Risk of New-Onset Atrial Fibrillation. Debonnaire P, Joyce E, Hiemstra Y, Mertens BJ, Atsma DE, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background: The value of left atrial (LA) diameter, volume, and strain to risk stratify hypertrophic cardiomyopathy patients for new-onset atrial fibrillation (AF) was explored. Methods and results: A total of 242 hypertrophic cardiomyopathy patients without AF history were evaluated by (speckle-tracking) echocardiography. During mean follow-up of 4.8±3.7 years, 41 patients (17%) developed new-onset AF. Multivariable analysis showed LA volume (≥37 mL/m2; hazard ratio, 2.68; 95% confidence interv... Abstract
Cited 169 times since 2017 (20.3 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 69, Issue 7, 1 1 2017, Pages 823-836 Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Webb TR, Erdmann J, Stirrups KE, Stitziel NO, Masca NG, Jansen H, Kanoni S, Nelson CP, Ferrario PG, König IR, Eicher JD, Johnson AD, Hamby SE, Betsholtz C, Ruusalepp A, Franzén O, Schadt EE, Björkegren JL, Weeke PE, Auer PL, Schick UM, Lu Y, Zhang H, Dube MP, Goel A, Farrall M, Peloso GM, Won HH, Do R, van Iperen E, Kruppa J, Mahajan A, Scott RA, Willenborg C, Braund PS, van Capelleveen JC, Doney AS, Donnelly LA, Asselta R, Merlini PA, Duga S, Marziliano N, Denny JC, Shaffer C, El-Mokhtari NE, Franke A, Heilmann S, Hengstenberg C, Hoffmann P, Holmen OL, Hveem K, Jansson JH, Jöckel KH, Kessler T, Kriebel J, Laugwitz KL, Marouli E, Martinelli N, McCarthy MI, Van Zuydam NR, Meisinger C, Esko T, Mihailov E, Escher SA, Alver M, Moebus S, Morris AD, Virtamo J, Nikpay M, Olivieri O, Provost S, AlQarawi A, Robertson NR, Akinsansya KO, Reilly DF, Vogt TF, Yin W, Asselbergs FW, Kooperberg C, Jackson RD, Stahl E, Müller-Nurasyid M, Strauch K, Varga TV, Waldenberger M, Wellcome Trust Case Control Consortium, Zeng L, Chow
Background: Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also associated with other diseases or traits. Objectives: This study sought to systematically test if genetic variants identified for non-CAD diseases/traits also associate with CAD and to undertake a comprehensive analysis of the extent of pleiotropy of all CAD loci. Methods: In discovery analyses involving 42,335 CAD... Abstract
Cited 379 times since 2017 (45.6 per year) source: EuropePMC
Nature, Volume 542, Issue 7640, 1 1 2017, Pages 186-190 Rare and low-frequency coding variants alter human adult height. Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, Rüeger S, Thorleifsson G, Justice AE, Lamparter D, Stirrups KE, Turcot V, Young KL, Winkler TW, Esko T, Karaderi T, Locke AE, Masca NG, Ng MC, Mudgal P, Rivas MA, Vedantam S, Mahajan A, Guo X, Abecasis G, Aben KK, Adair LS, Alam DS, Albrecht E, Allin KH, Allison M, Amouyel P, Appel EV, Arveiler D, Asselbergs FW, Auer PL, Balkau B, Banas B, Bang LE, Benn M, Bergmann S, Bielak LF, Blüher M, Boeing H, Boerwinkle E, Böger CA, Bonnycastle LL, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Burt AA, Butterworth AS, Carey DJ, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Galbany JC, Cox AJ, Cuellar-Partida G, Danesh J, Davies G, de Bakker PI, de Borst GJ, de Denus S, de Groot MC, de Mutsert R, Deary IJ, Dedoussis G, Demerath EW, den Hollander AI, Dennis JG, Di Angelantonio E, Drenos F, Du M,
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencies (in the range of 0.1-4.8%) and effects of up to 2 centimetres per allele (such as those in IHH, STC2, AR and CRISPLD2), greater than ten times the average effect of common variants. In functional follow-up studies, rare height-increasing alleles of... Abstract
Cited 9 times since 2017 (1.1 per year) source: EuropePMC
Nature reviews. Cardiology, Volume 14, Issue 4, 27 4 2017, Pages 209-223 Advanced imaging in valvular heart disease. Bax JJ, Delgado V
Although echocardiography remains the mainstay imaging technique for the evaluation of patients with valvular heart disease (VHD), innovations in noninvasive imaging in the past few years have provided new insights into the pathophysiology and quantification of VHD, early detection of left ventricular (LV) dysfunction, and advanced prognostic assessment. The severity grading of valve dysfunction has been refined with the use of Doppler echocardiography, cardiac magnetic resonance (CMR), and CT i... Abstract
Cited 1 times since 2017 (0.1 per year) source: EuropePMC
The Eurasian journal of medicine, Volume 49, Issue 1, 25 4 2017, Pages 69-71 A Systemic-Onset Juvenile Idiopathic Arthritis Patient with Reduced Anakinra Treatment Admitted with an Attack. Yilmaz D, Akcan M, Terlemez S, Sonmez F, Akcan AB
Interleukin-1 plays an important role in the pathogenesis of systemic-onset juvenile idiopathic arthritis (SoJIA), and the use of anti-interleukin-1 therapy has been increasing. We report a case of a 14-year-old male patient with SoJIA. He was in remission with anakinra treatment for almost 2 years. When we extended the therapeutic range and decreased the dose (1 mg/kg twice a week), he developed symptoms mimicking pulmonary embolism and cardiac ischemia. Increased cardiac enzyme levels and echo... Abstract