6131 results
Cited 51 times since 2010 (3.6 per year)
source: EuropePMC
AJR. American journal of roentgenology,
Volume 195, Issue 6, 1 1 2010, Pages 1299-1305
Assessment of Agatston coronary artery calcium score using contrast-enhanced CT coronary angiography.
van der Bijl N, Joemai RM, Geleijns J, Bax JJ, Schuijf JD, de Roos A, Kroft LJ
Objective: The purpose of this article is to evaluate to what extent Agatston scores may be derived from CT coronary angiography (CTA) examinations, compared with traditional unenhanced CT calcium scores. Materials and methods: Fifty patients with a CT calcium score-Agatston score of zero and 50 patients with a CT calcium score-Agatston score of 1 or greater whose CT calcium scores had been calculated and who had undergone CTA using volumetric 320-MDCT were included. Agatston scores were obtaine...
Abstract
Cited 17 times since 2010 (1.2 per year)
source: EuropePMC
Human mutation,
Volume 31, Issue 12, 1 1 2010, Pages E1915-27
The clinical spectrum of missense mutations of the first aspartic acid of cbEGF-like domains in fibrillin-1 including a recessive family.
Hilhorst-Hofstee Y, Rijlaarsdam ME, Scholte AJ, Swart-van den Berg M, Versteegh MI, van der Schoot-van Velzen I, Schäbitz HJ, Bijlsma EK, Baars MJ, Kerstjens-Frederikse WS, Giltay JC, Hamel BC, Breuning MH, Pals G
Marfan syndrome (MFS) is a dominant disorder with a recognizable phenotype. In most patients with the classical phenotype mutations are found in the fibrillin-1 gene (FBN1) on chromosome 15q21. It is thought that most mutations act in a dominant negative way or through haploinsufficiency. In 9 index cases referred for MFS we detected heterozygous missense mutations in FBN1 predicted to substitute the first aspartic acid of different calcium-binding Epidermal Growth Factor-like (cbEGF) fibrillin-...
Abstract
Cited 16 times since 2010 (1.1 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 90, Issue 6, 1 1 2010, Pages 1913-1920
Clinical and functional effects of restrictive mitral annuloplasty at midterm follow-up in heart failure patients.
ten Brinke EA, Klautz RJ, Tulner SA, Verwey HF, Bax JJ, Delgado V, Holman ER, Schalij MJ, van der Wall EE, Braun J, Versteegh MI, Dion RA, Steendijk P
Background: Restrictive mitral annuloplasty (RMA) is increasingly applied to treat functional mitral regurgitation in heart failure patients. Previous studies indicated beneficial clinical effects with low recurrence rates. However, the underlying pathophysiology is complex and outcome in terms of left ventricular function is not well known. We investigated chronic effects of RMA on ventricular function in relation to clinical outcome. Methods: Heart failure patients (n = 11) with severe mitral...
Abstract
Cited 7 times since 2010 (0.5 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 40, Issue 6, 1 1 2010, Pages 696-707
Assessing the quality of surgical care in vascular surgery; moving from outcome towards structural and process measures.
Ploeg AJ, Flu HC, Lardenoye JH, Hamming JF, Breslau PJ
Objectives: This study presents a review of studies reporting on quality of care in vascular surgery. The aim of this study was to provide insight in quality improvement initiatives in vascular surgery. Design: Original data were collected from MEDLINE and EMBASE databases. Inclusion criteria were: description of one of the three factors of quality of care, e.g. process, outcome or structure and prospectively described. All articles identified were ascribed to a domain of quality of care. Result...
Abstract
Cited 129 times since 2010 (9 per year)
source: EuropePMC
Circulation,
Volume 122, Issue 24, 29 5 2010, Pages 2538-2544
Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus.
Ng AC, Delgado V, Bertini M, van der Meer RW, Rijzewijk LJ, Hooi Ewe S, Siebelink HM, Smit JW, Diamant M, Romijn JA, de Roos A, Leung DY, Lamb HJ, Bax JJ
Background: Magnetic resonance spectroscopy can quantify myocardial triglyceride content in type 2 diabetic patients. Its relation to alterations in left (LV) and right (RV) ventricular myocardial functions is unknown. Methods and results: A total of 42 men with type 2 diabetes mellitus were recruited. Exclusion criteria included hemoglobin A(1c) >8.5, known cardiovascular disease, diabetes-related complications, or blood pressure >150/85 mm Hg. Myocardial ischemia was excluded by a negati...
Abstract
Cited 16 times since 2010 (1.1 per year)
source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology,
Volume 12, Issue 2, 24 4 2010, Pages 148-155
Subclinical left ventricular dysfunction and coronary atherosclerosis in asymptomatic patients with type 2 diabetes.
Scholte AJ, Nucifora G, Delgado V, Djaberi R, Boogers MJ, Schuijf JD, Kharagjitsingh AV, Jukema JW, van der Wall EE, Kroft LJ, de Roos A, Bax JJ
Aims: The aim of the present study was to evaluate whether subclinical left ventricular (LV) systolic dysfunction is independently related to subclinical coronary atherosclerosis in type 2 diabetic patients and if it could provide incremental information over baseline characteristics to identify high-risk patients. Methods and results: A total of 234 asymptomatic, type 2 diabetic patients without overt LV systolic dysfunction underwent coronary artery calcium (CAC) scoring and two-dimensional ec...
Abstract
Cited 42 times since 2010 (2.9 per year)
source: EuropePMC
Annals of surgical oncology,
Volume 18, Issue 4, 16 3 2010, Pages 1006-1014
Clinical translation of ex vivo sentinel lymph node mapping for colorectal cancer using invisible near-infrared fluorescence light.
Hutteman M, Choi HS, Mieog JS, van der Vorst JR, Ashitate Y, Kuppen PJ, van Groningen MC, Löwik CW, Smit VT, van de Velde CJ, Frangioni JV, Vahrmeijer AL
Background: Sentinel lymph node (SLN) mapping in colorectal cancer may have prognostic and therapeutic significance; however, currently available techniques are not optimal. We hypothesized that the combination of invisible near-infrared (NIR) fluorescent light and ex vivo injection could solve remaining problems of SLN mapping in colorectal cancer. Methods: The FLARE imaging system was used for real-time identification of SLNs after injection of the NIR lymphatic tracer HSA800 in the colon and...
Abstract
Cited 32 times since 2010 (2.2 per year)
source: EuropePMC
Atherosclerosis,
Volume 214, Issue 2, 13 2 2010, Pages 295-300
Atorvastatin inhibits plaque development and adventitial neovascularization in ApoE deficient mice independent of plasma cholesterol levels.
Bot I, Jukema JW, Lankhuizen IM, van Berkel TJ, Biessen EA
Excessive adventitial neovascularization is one of the hallmarks of atherosclerotic plaque progression and is associated with an increased plaque burden by facilitating leukocyte influx and perivascular inflammation. Statins act atheroprotective by reducing plasma cholesterol levels and by quenching inflammation, but recent studies suggest that they may also affect neovascularization. In this study, we aimed to investigate this notion in apoE(-/-) mice. Advanced carotid artery lesions were induc...
Abstract
Cited 385 times since 2010 (26.9 per year)
source: EuropePMC
Circulation. Heart failure,
Volume 4, Issue 1, 12 2 2010, Pages 44-52
Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.
Westermann D, Lindner D, Kasner M, Zietsch C, Savvatis K, Escher F, von Schlippenbach J, Skurk C, Steendijk P, Riad A, Poller W, Schultheiss HP, Tschöpe C
Background: The pathophysiology of heart failure with normal ejection fraction (HFNEF) is still under discussion. Here we report the influence of cardiac inflammation on extracellular matrix (ECM) remodeling in patients with HFNEF. Methods and results: We investigated left ventricular systolic and diastolic function in 20 patients with HFNEF and 8 control patients by conductance catheter methods and echocardiography. Endomyocardial biopsy samples were also obtained, and ECM proteins as well as c...
Abstract
Cited 18 times since 2010 (1.3 per year)
source: EuropePMC
BMC musculoskeletal disorders,
Volume 11, 12 2 2010, Pages 263
Functional treatment versus plaster for simple elbow dislocations (FuncSiE): a randomized trial.
de Haan J, den Hartog D, Tuinebreijer WE, Iordens GI, Breederveld RS, Bronkhorst MW, Bruijninckx MM, De Vries MR, Dwars BJ, Eygendaal D, Haverlag R, Meylaerts SA, Mulder JW, Ponsen KJ, Roerdink WH, Roukema GR, Schipper IB, Schouten MA, Sintenie JB, Sivro S, Van den Brand JG, Van der Meulen HG, Van Thiel TP, Van Vugt AB, Verleisdonk EJ, Vroemen JP, Waleboer M, Willems WJ, Polinder S, Patka P, van Lieshout EM, Schep NW
Background: Elbow dislocations can be classified as simple or complex. Simple dislocations are characterized by the absence of fractures, while complex dislocations are associated with fractures. After reduction of a simple dislocation, treatment options include immobilization in a static plaster for different periods of time or so-called functional treatment. Functional treatment is characterized by early active motion within the limits of pain with or without the use of a sling or hinged brace...
Abstract
Cited 2 times since 2010 (0.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 97, Issue 1, 11 2 2010, Pages 1-3
Can cardiac [123I]m-iodobenzylguanidine imaging be used for risk stratification of patients with acute myocardial infarction?
Boogers MJ, Bax JJ
Abstract
Cited 13 times since 2010 (0.9 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 97, Issue 2, 8 2 2010, Pages 143-150
Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies.
Pons D, Trompet S, de Craen AJ, Thijssen PE, Quax PH, de Vries MR, Wierda RJ, van den Elsen PJ, Monraats PS, Ewing MM, Heijmans BT, Slagboom PE, Zwinderman AH, Doevendans PA, Tio RA, de Winter RJ, de Maat MP, Iakoubova OA, Sattar N, Shepherd J, Westendorp RG, Jukema JW, PROSPER study group, WOSCOPS study group, GENDER study group
Aims: This study was designed to investigate the counterbalancing influence of genetic variation in the promoter of the gene encoding P300/CBP associated factor (PCAF), a lysine acetyltransferase (KAT), on coronary heart disease (CHD) and mortality. Methods and results: The association of genetic variation in the PCAF-gene with CHD, restenosis and mortality was investigated in three large cohorts. The results were combined to examine overall effects on CHD mortality and on restenosis risk. Compa...
Abstract
Cited 26 times since 2010 (1.8 per year)
source: EuropePMC
The American journal of cardiology,
Volume 106, Issue 12, 4 1 2010, Pages 1675-1679
Impact of clinical presentation and pretest likelihood on the relation between calcium score and computed tomographic coronary angiography.
van Werkhoven JM, de Boer SM, Schuijf JD, Cademartiri F, Maffei E, Jukema JW, Boogers MJ, Kroft LJ, de Roos A, Bax JJ
The purpose of the present study was to assess the impact of clinical presentation and pretest likelihood on the relation between coronary calcium score (CCS) and computed tomographic coronary angiography (CTA) to determine the role of CCS as a gatekeeper to CTA in patients presenting with chest pain. In 576 patients with suspected coronary artery disease (CAD), CCS and CTA were performed. CCS was categorized as 0, 1 to 400, and >400. On CT angiogram the presence of significant CAD (≥50% lumi...
Abstract
Cited 29 times since 2010 (2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 96, Issue 21, 1 1 2010, Pages 1737-1743
Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial layers.
Bertini M, Delgado V, Nucifora G, Ajmone Marsan N, Ng AC, Shanks M, Antoni ML, van de Veire NR, van Bommel RJ, Rapezzi C, Schalij MJ, Bax JJ
Objective: Subendocardial and subepicardial layers have opposite orientation of the myofibres and they are differently affected by coronary artery disease. This study investigated the differences in subendocardial and subepicardial left ventricular (LV) twist in patients with coronary artery disease. Methods: 214 patients were included in the study: 60 with first ST elevation myocardial infarction (STEMI), 111 with chronic ischaemic heart failure (HF) and 43 normal subjects. Real-time three-dime...
Abstract
Cited 5 times since 2010 (0.3 per year)
source: EuropePMC
Nature reviews. Cardiology,
Volume 7, Issue 11, 1 1 2010, Pages 604-606
Cardiomyopathies: Myocardial fibrosis assessed by CMR to predict events in HCM.
Ajmone Marsan N, Bax JJ
Abstract
Cited 30 times since 2010 (2.1 per year)
source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 6, Issue 5, 1 1 2010, Pages 643-652
Multimodality imaging in transcatheter aortic valve implantation: key steps to assess procedural feasibility.
Delgado V, Ewe SH, Ng AC, van der Kley F, Marsan NA, Schuijf JD, Schalij MJ, Bax JJ
Transcatheter aortic valve implantation (TAVI) has been an important breakthrough in the treatment of patients with symptomatic, severe aortic stenosis and contraindications for surgical aortic valve replacement. Accurate aortic root measurements and evaluation of spatial relationships with the coronary ostia are crucial in pre-operative TAVI assessment. In addition, characterisation of the peripheral artery anatomy and aorta is an important key step in the procedural feasibility evaluation. The...
Abstract
Cited 14 times since 2010 (1 per year)
source: EuropePMC
Haemophilia : the official journal of the World Federation of Hemophilia,
Volume 16, Issue 6, 1 1 2010, Pages 888-891
A single centre experience in circumcision of haemophilia patients: Izmir protocol.
Yilmaz D, Akin M, Ay Y, Balkan C, Celik A, Ergün O, Kavakli K
Haemophiliacs and their families consider that circumcision is a very important step to become a member of society and it is a social obligation for men in Turkey. Although bleeding risk is high, almost all haemophiliacs would like to be circumcised in Turkish society. The aim of this study was to evaluate our experience in circumcision of haemophilia patients and define efficacy, safety and complication rates of our protocol, called 'Izmir protocol'. In this study, we retrospectivel...
Abstract
Cited 10 times since 2010 (0.7 per year)
source: EuropePMC
American heart journal,
Volume 160, Issue 5, 1 1 2010, Pages 812-818
Rationale and design of a trial on the effect of angiotensin II receptor blockers on the function of the systemic right ventricle.
van der Bom T, Winter MM, Bouma BJ, Groenink M, Vliegen HW, Pieper PG, van Dijk AP, Sieswerda GT, Roos-Hesslink JW, Zwinderman AH, Mulder BJ
Background: Angiotensin II receptor blockers have been proven to be beneficial in left ventricular failure. In patients with a morphologic right ventricle supporting the systemic circulation, its efficacy has not yet been established. Methods: We designed a multicenter, prospective, randomized, double-blind, placebo-controlled trial studying the effect of valsartan in patients with a systemic right ventricle due to a congenitally or surgically corrected transposition of the great arteries. The p...
Abstract
Cited 25 times since 2010 (1.7 per year)
source: EuropePMC
The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons,
Volume 49, Issue 6, 1 1 2010, Pages 541-545
Chopart joint injury: a study of outcome and morbidity.
van Dorp KB, de Vries MR, van der Elst M, Schepers T
Injuries involving the Chopart joint complex are relatively rare and frequently missed or misdiagnosed, often leading to a poor functional outcome. This study was performed to determine the outcome and morbidity in patients with Chopart joint injuries, and to increase awareness of this severe injury. Patients with a Chopart dislocation or fracture-dislocation, treated between January 2004 and January 2010, were identified using the appropriate diagnosis code and reviewing all radiographs of pati...
Abstract
Cited 18 times since 2010 (1.3 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 21, Issue 11, 1 1 2010, Pages 1284-1292
Electrical activation of sinus venosus myocardium and expression patterns of RhoA and Isl-1 in the chick embryo.
Vicente-Steijn R, Kolditz DP, Mahtab EA, Askar SF, Bax NA, VAN DER Graaf LM, Wisse LJ, Passier R, Pijnappels DA, Schalij MJ, Poelmann RE, Gittenberger-DE Groot AC, Jongbloed MR
Unlabelled: Electrical Activity and RhoA in the Embryo. Introduction: Myocardium at the venous pole (sinus venosus) of the heart has gained clinical interest as arrhythmias can be initiated from this area. During development, sinus venosus myocardium is incorporated to the primary heart tube and expresses different markers than primary myocardium. We aimed to elucidate the development of sinus venosus myocardium, including the sinoatrial node (SAN), by studying expression patterns of RhoA in rel...
Abstract
