6177 results
Cited 32 times since 2006 (1.7 per year)
source: EuropePMC
Molecular therapy : the journal of the American Society of Gene Therapy,
Volume 13, Issue 5, 26 4 2006, Pages 976-986
Transduction of myogenic cells by retargeted dual high-capacity hybrid viral vectors: robust dystrophin synthesis in duchenne muscular dystrophy muscle cells.
Gonçalves MA, Holkers M, Cudré-Mauroux C, van Nierop GP, Knaän-Shanzer S, van der Velde I, Valerio D, de Vries AA
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene (DMD), making it amenable to gene- or cell-based therapies. Another possible treatment entails the combination of both principles by transplantation of autologous myogenic cells after their genetic complementation. This approach requires efficient and stable transduction of these cells with recombinant DMD. Recently, we generated a dual high-capacity (hc) adenovirus (Ad)-adeno-associated virus (AAV) hybrid vector (HV...
Abstract
Cited 9 times since 2006 (0.5 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 29, Issue 3, 19 3 2006, Pages 367-373
Outcome after mitral valve repair for acute and healed infective endocarditis.
Feringa HH, Bax JJ, Klein P, Klautz RJ, Braun J, van der Wall EE, Poldermans D, Dion RA
Objective: To evaluate the long-term clinical and echocardiographic outcomes after mitral valve surgery for acute and healed infective endocarditis. Methods: Of 37 consecutive patients presenting with native mitral valve endocarditis, mitral valve repair (MVRep) was feasible in 34 (92%) patients. In 17 (50%) patients, surgery was indicated during antibiotic therapy (acute endocarditis), whereas 17 (50%) underwent surgery after antibiotic therapy was completed (healed endocarditis). Patients were...
Abstract
Cited 68 times since 2006 (3.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 97, Issue 5, 10 2 2006, Pages 662-670
Histology of vascular myocardial wall of left atrial body after pulmonary venous incorporation.
Douglas YL, Jongbloed MR, Gittenberger-de Groot AC, Evers D, Dion RA, Voigt P, Bartelings MM, Schalij MJ, Ebels T, DeRuiter MC
During embryonic development, the common pulmonary vein (PV) becomes incorporated into the left atrium, giving rise to separate PV ostia. We describe the consequences of this incorporation process for the histology of the left atrium and the possible clinical implications. The histology of the left atrial (LA) wall in relation to PV incorporation was studied immunohistochemically in 16 human embryos and fetuses, 1 neonate, and 5 adults. The PV wall, surrounded by extrapericardially differentiate...
Abstract
Cited 5 times since 2006 (0.3 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 47, Issue 1, 1 1 2006, Pages 68-73
Impact of diabetes mellitus on prediction of clinical outcome after coronary revascularization by 18F-FDG SPECT in patients with ischemic left ventricular dysfunction.
Schinkel AF, Poldermans D, Rizzello V, van Domburg RT, Valkema R, Elhendy A, Biagini E, Krenning EP, Simoons ML, Bax JJ
Unlabelled: Nuclear imaging using (18)F-FDG is an established method for the noninvasive assessment of myocardial viability. Data on the value of (18)F-FDG imaging in patients with diabetes mellitus are scarce. The aim of this study was to assess whether, in patients with diabetes mellitus and ischemic left ventricular (LV) dysfunction, (18)F-FDG imaging can predict improvement of LV function and heart failure symptoms after coronary revascularization. Methods: A total of 130 consecutive patient...
Abstract
Cited 1 times since 2006 (0.1 per year)
source: EuropePMC
Annals of nuclear medicine,
Volume 20, Issue 1, 1 1 2006, Pages 51-56
Effect of left ventricular function on diagnostic accuracy of FDG SPECT.
Matsunari I, Bax JJ, Blanksma PK, Visser FC, Kanayama S, Yoneyama T, Nekolla SG, Tonami N, Hisada K
Objectives: Fluorine-18 fluorodeoxyglucose (FDG) SPECT has emerged as an alternative to dedicated PET imaging. However, it remains uncertain whether FDG SPECT is an as accurate for viability assessment as FDG PET in patients with severely reduced left ventricular function. The aim of the study was to assess the diagnostic accuracy of FDG SPECT in a head-to-head comparison with FDG PET, and divide the patients according to the severity of left ventricular dysfunction. Methods: A total of 47 patie...
Abstract
Cited 23 times since 2006 (1.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 13, Issue 1, 1 1 2006, Pages 123-126
Multimodality imaging to diagnose takotsubo cardiomyopathy.
Scholte AJ, Bax JJ, Stokkel MP, Plokker T, Kaandorp TA, Lamb HJ, de Roos A, van der Wall EE
Abstract
Cited 27 times since 2006 (1.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 13, Issue 1, 1 1 2006, Pages 11-18
Screening of asymptomatic patients with type 2 diabetes mellitus for silent coronary artery disease: combined use of stress myocardial perfusion imaging and coronary calcium scoring.
Scholte AJ, Bax JJ, Wackers FJ
Diabetes mellitus and coronary artery disease constitute an ominous clinical combination. Rates of morbidity and mortality as a result of cardiovascular complications are high in patients with type 2 diabetes mellitus. Screening for silent coronary artery disease, to detect the disease in an early stage and to be able to initiate early appropriate treatment, has recently become an important focus of clinical investigation. Recent prospective studies have shown that the overall prevalence of sile...
Abstract
Cited 24 times since 2006 (1.2 per year)
source: Scopus
Animal reproduction science,
Volume 91, Issue 1-2, 1 1 2006, Pages 55-76
Pregnancy effects on distribution of progesterone receptors, oestrogen receptor alpha, glucocorticoid receptors, Ki-67 antigen and apoptosis in the bovine interplacentomal uterine wall and foetal membranes.
Boos A, Kohtes J, Janssen V, Mülling C, Stelljes A, Zerbe H, Hässig M, Thole HH
Until recently, studies dealing with the uterus of the pregnant cow focus primarily on the placentome or on early and late pregnancy. Thus, there is a paucity of information about many aspects of the interplacentomal uterine wall including adherent foetal membranes. Corresponding tissue specimens were collected at the slaughterhouse and in animals undergoing premature caesarean section. Two specimens per month of pregnancy were assessed immunohistochemically for progesterone receptors, oestrogen...
Abstract
Cited 5 times since 2006 (0.3 per year)
source: EuropePMC
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis,
Volume 17, Issue 1, 1 1 2006, Pages 57-58
Massive pulmonary embolism with cardiac arrest after an intracardiac electrophysiological study: a strong case for venous thromboprophylaxis.
Bauer MP, Vliegen HW, Huisman MV
A 47-year-old woman was referred to our hospital for an intracardiac electrophysiological study. The procedure was complicated by cardiac arrest due to massive pulmonary embolism, which only successfully resolved after the administration of a thrombolytic agent. This case suggests that there is a real risk of venous thromboembolism in certain patients during electrophysiological studies. Therefore, a consensus should be reached concerning the prevention of venous thromboembolism during these pro...
Abstract
Cited 19 times since 2006 (1 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 150, Issue 1, 1 1 2006, Pages 18-23
[The practice guideline 'Diagnosis and treatment of familial hypercholesterolaemia' of the Dutch Health Care Insurance Board].
Walma EP, Visseren FL, Jukema JW, Kastelein JJ, Hoes AW, Stalenhoef AF
Until 2010, the Dutch ministry of Health, Welfare and Sport will fund a nationwide project to identify the approximately 40,000 patients with familial hypercholesterolaemia (FH) in the Netherlands. The Health Care Insurance Board will coordinate the project and safeguard its quality, while the 'Stichting Opsporing Erfelijke Hypercholesterolemie' [Foundation for the Detection of Hereditary Hypercholesterolaemia], with its national network of genetic fieldworkers, will search systematica...
Abstract
Cited 15 times since 2006 (0.8 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 17, Issue 1, 1 1 2006, Pages 101-103
Acceleration-dependent left bundle branch block with severe left ventricular dyssynchrony results in acute heart failure: are there more patients who benefit from cardiac resynchronization therapy?
Zeppenfeld K, Schalij MJ, Bleeker GB, Holman ER, Bax JJ
Cardiac resynchronization therapy (CRT) has been proposed to improve hemodynamics in patients with heart failure and left bundle branch block (LBBB) by resynchronization of left ventricular (LV) dyssynchrony. The current report concerns a patient with narrow QRS complex without LV dyssynchrony who experienced an acute exacerbation of heart failure following exercise. Careful analysis revealed that an increase of heart rate induced acceleration-dependent LBBB with severe LV dyssynchrony and mitra...
Abstract
Cited 27 times since 2006 (1.4 per year)
source: EuropePMC
ASAIO journal (American Society for Artificial Internal Organs : 1992),
Volume 52, Issue 1, 1 1 2006, Pages 4-8
Modeling ventricular function during cardiac assist: does time-varying elastance work?
Vandenberghe S, Segers P, Steendijk P, Meyns B, Dion RA, Antaki JF, Verdonck P
The time-varying elastance theory of Suga et al. is widely used to simulate left ventricular function in mathematical models and in contemporary in vitro models. We investigated the validity of this theory in the presence of a left ventricular assist device. Left ventricular pressure and volume data are presented that demonstrate the heart-device interaction for a positive-displacement pump (Novacor) and a rotary blood pump (Medos). The Novacor was implanted in a calf and used in fixed-rate mode...
Abstract
Critical care medicine,
Volume 34, Issue 1, 1 1 2006, Pages 255-257
The role of nitric oxide signaling in sepsis-induced myocardial dysfunction.
Steendijk P
Abstract
Cited 35 times since 2006 (1.8 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 33, Issue 1, 1 1 2006, Pages 93-104
Diagnostic and prognostic value of non-invasive imaging in known or suspected coronary artery disease.
Schuijf JD, Poldermans D, Shaw LJ, Jukema JW, Lamb HJ, de Roos A, Wijns W, van der Wall EE, Bax JJ
The role of non-invasive imaging techniques in the evaluation of patients with suspected or known coronary artery disease (CAD) has increased exponentially over the past decade. The traditionally available imaging modalities, including nuclear imaging, stress echocardiography and magnetic resonance imaging (MRI), have relied on detection of CAD by visualisation of its functional consequences (i.e. ischaemia). However, extensive research is being invested in the development of non-invasive anatom...
Abstract
Cited 21 times since 2006 (1.1 per year)
source: EuropePMC
Crisis,
Volume 27, Issue 2, 1 1 2006, Pages 77-81
High rates of suicide and attempted suicide using pesticides in Nickerie, Suriname, South America.
Graafsma T, Kerkhof A, Gibson D, Badloe R, van de Beek LM
Suicide and attempted suicide are identified as a serious mental health problem in Suriname, especially in the district of Nickerie. An epidemiological study in the Nickerie catchment area revealed high rates of suicide (48 per 100,000) and attempted suicide (207 per 100,000) on average in the years 2000-2004. Particularly remarkable is the high number of attempted suicides among males (49%), and the use of pesticides in both fatal (55%) and nonfatal suicidal behavior (44%). Probably this high i...
Abstract
Cited 1 times since 2006 (0.1 per year)
source: EuropePMC
Heart rhythm,
Volume 3, Issue 1, 1 1 2006, Pages 50-51
Endoscopic fiberoptic balloon catheter: a new step in imaging-guided anatomically based catheter ablation for atrial fibrillation?
Tops LF, Schalij MJ, Bax JJ
Abstract
Cited 6 times since 2005 (0.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 97, Issue 4, 22 4 2005, Pages 462-465
Enhanced sensitivity of dobutamine stress echocardiography by observing wall motion abnormalities during the recovery phase after acute beta-blocker administration.
Karagiannis SE, Bax JJ, Elhendy A, Feringa HH, Cokkinos DV, van Domburg R, Simoons M, Poldermans D
Dobutamine stress echocardiography (DSE) has a modest sensitivity for detecting single-vessel coronary artery disease (CAD). This study assessed the additional diagnostic value of new or worsening wall motion abnormalities during recovery after acute administration of beta blockers. The study population consisted of 200 patients (mean 59 +/- 11 years of age, 144 men), who underwent DSE. Images were acquired at rest, low dose, peak dose, and during recovery. Patients received intravenous metoprol...
Abstract
Cited 54 times since 2005 (2.8 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 22, Issue 1, 13 2 2005, Pages 63-80
Imaging techniques in nuclear cardiology for the assessment of myocardial viability.
Slart RH, Bax JJ, van Veldhuisen DJ, van der Wall EE, Dierckx RA, Jager PL
The assessment of myocardial viability has become an important aspect of the diagnostic and prognostic work-up of patients with ischemic cardiomyopathy. Although revascularization may be considered in patients with sufficient viable myocardium, patients with predominantly scar tissue should be treated medically. Patients with left ventricular dysfunction who have viable myocardium are the patients at highest risk because of the potential for ischemia but at the same time benefit most from revasc...
Abstract
Cited 4 times since 2005 (0.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 22, Issue 1, 10 2 2005, Pages 107-109
Noninvasive visualization of the coronary arteries with multi-slice computed tomography; influence of heart rate on diagnostic accuracy.
Henneman MM, Bax JJ, Schuijf JD, van der Wall EE
Abstract
Cited 50 times since 2005 (2.6 per year)
source: EuropePMC
Human molecular genetics,
Volume 15, Issue 2, 1 1 2005, Pages 213-221
Human mesenchymal stem cells ectopically expressing full-length dystrophin can complement Duchenne muscular dystrophy myotubes by cell fusion.
Gonçalves MA, de Vries AA, Holkers M, van de Watering MJ, van der Velde I, van Nierop GP, Valerio D, Knaän-Shanzer S
Duchenne muscular dystrophy (DMD) is the most prevalent inheritable muscle disease. It is caused by mutations in the approximately 2.5-megabase dystrophin (Dys) encoding gene. Therapeutic attempts at DMD have relied on injection of allogeneic Dys-positive myoblasts. The immune rejection of these cells and their limited availability have prompted the search for alternative therapies and sources of myogenic cells. Stem cell-based gene therapy aims to restore tissue function by the transplantation...
Abstract
