Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6931 results
Cited 15 times since 2014 (1.4 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 100, Issue 17, 16 3 2014, Pages 1360-1365 Persistent neo-aortic growth during adulthood in patients after an arterial switch operation. van der Bom T, van der Palen RL, Bouma BJ, van Veldhuisen SL, Vliegen HW, Konings TC, Zwinderman AH, Blom NA, Koolbergen DR, Hazekamp MG, Mulder BJ
Objective: After the arterial switch operation (ASO), disproportional neo-aortic growth during childhood has been reported. Even though it has been suggested neo-aortic dilation will stabilise in adulthood, data are lacking. The aim of this study was to assess the change in neo-aortic dimensions, prevalence of neo-aortic dilation >40 mm and long-term outcome in adults who underwent ASO in childhood. Methods: All 116 ASO patients operated in a tertiary referral centre and born before 1995 were... Abstract
American heart journal, Volume 168, Issue 1, 14 2 2014, Pages e5 Response to the letter to the editor by Ariza-Solé et al. Velders MA, James SK, Libungan B, Sarno G, Fröbert O, Carlsson J, Schalij MJ, Albertsson P, Lagerqvist B
Cited 11 times since 2014 (1 per year) source: EuropePMC
Experimental cell research, Volume 327, Issue 2, 13 2 2014, Pages 297-306 Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones. Dambrot C, Buermans HP, Varga E, Kosmidis G, Langenberg K, Casini S, Elliott DA, Dinnyes A, Atsma DE, Mummery CL, Braam SR, Davis RP
Recent methodological advances have improved the ease and efficiency of generating human induced pluripotent stem cells (hiPSCs), but this now typically results in a greater number of hiPSC clones being derived than can be wholly characterized. It is therefore imperative that methods are developed which facilitate rapid selection of hiPSC clones most suited for the downstream research aims. Here we describe a combination of procedures enabling the simultaneous screening of multiple clones to det... Abstract
Cited 12 times since 2014 (1.1 per year) source: EuropePMC
Circulation. Cardiovascular quality and outcomes, Volume 7, Issue 3, 13 2 2014, Pages 437-444 Left ventricular reverse remodeling, device-related adverse events, and long-term outcome after cardiac resynchronization therapy in the elderly. Höke U, Putter H, Van Der Velde ET, Schalij MJ, Delgado V, Bax JJ, Marsan NA
Background: Limited data are available on efficacy, safety, and long-term prognosis after cardiac resynchronization therapy (CRT) in elderly patients. We aimed at evaluating the effect of CRT, device-related adverse events, and long-term outcome after CRT among elderly patients. Methods and results: A total of 798 CRT recipients (208 elderly: age, ≥75 years; 590 nonelderly: age, Abstract
Cited 7 times since 2014 (0.6 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 30, Issue 6, 10 2 2014, Pages 1151-1159 Associations of atherosclerosis in the descending thoracic aorta on CTA with arterial stiffness and chronic kidney disease in asymptomatic patients with diabetes mellitus. Roos CJ, Delgado V, de Koning EJ, Rabelink TJ, Jukema JW, Bax JJ, Scholte AJ
The relation between atherosclerosis in the descending thoracic aortic (DTA), arterial stiffness and chronic kidney disease (CKD) in patients with diabetes mellitus (DM) remains unclear. The current aim was to evaluate associations of DTA atherosclerosis with arterial stiffness and parameters of CKD in asymptomatic patients with DM. A total of 213 asymptomatic patients with diabetes (mean age 52 years, 56% men) underwent cardiovascular risk assessment including multi-slice computed tomography (f... Abstract
Cited 1 times since 2014 (0.1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 101, Issue 3, 9 2 2014, Pages 230-239 Cardiac resynchronisation therapy in populations underrepresented in randomised controlled trials. Höke U, Delgado V, Marsan NA, Bax JJ
Cited 9 times since 2014 (0.8 per year) source: EuropePMC
Atherosclerosis, Volume 235, Issue 1, 8 2 2014, Pages 176-181 ABCA1 gene variation and heart disease risk reduction in the elderly during pravastatin treatment. Akao H, Polisecki E, Schaefer EJ, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Packard C, Buckley BM, Kajinami K, PROspective Study of Pravastatin in the Elderly at Risk Investigator
Aims: Our goals were to examine the relationships of a specific ATP-binding cassette transporter A1 (ABCA1) variant, rs2230806 (R219K), on baseline lipids, low-density lipoprotein cholesterol (LDL-C) lowering due to pravastatin, baseline heart disease, and cardiac endpoints on trial. Methods and results: The ABCA1 R219K variant was assessed in 5414 participants in PROSPER (PROspective Study of Pravastatin in the Elderly at Risk) (mean age 75.3 years), who had been randomized to pravastatin 40 mg... Abstract
Cited 5 times since 2014 (0.5 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 22, Issue 5, 1 1 2014, Pages 240-245 Unroofed coronary sinus newly diagnosed in adult patients after corrected congenital heart disease. Pérez Matos AJ, Planken RN, Bouma BJ, Groenink M, Backx AP, de Winter RJ, Koolbergen DR, Mulder BJ, Boekholdt SM
Patients with congenital heart disease corrected in early childhood may later in life present with cardiac symptoms caused by other associated congenital anomalies that were initially not diagnosed. Nowadays, several noninvasive imaging modalities are available for the visualisation of cardiac anatomy in great detail. We describe two patients with an unroofed coronary sinus, a rare congenital anomaly which could be diagnosed using a combination of modalities including echocardiography, cardiac C... Abstract
Cited 40 times since 2014 (3.6 per year) source: EuropePMC
Future virology, Volume 9, Issue 5, 1 1 2014, Pages 513-524 Avian influenza A viruses: from zoonosis to pandemic. Richard M, de Graaf M, Herfst S
Zoonotic influenza A viruses originating from the animal reservoir pose a threat for humans, as they have the ability to trigger pandemics upon adaptation to and invasion of an immunologically naive population. Of particular concern are the H5N1 viruses that continue to circulate in poultry in numerous countries in Europe, Asia and Africa, and the recently emerged H7N9 viruses in China, due to their relatively high number of human fatalities and pandemic potential. To start a pandemic, zoonotic... Abstract
Cited 7 times since 2014 (0.6 per year) source: EuropePMC
Atherosclerosis, Volume 235, Issue 1, 26 4 2014, Pages 58-64 In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study. Postmus I, Johnson PC, Trompet S, de Craen AJ, Slagboom PE, Devlin JJ, Shiffman D, Sacks FM, Kearney PM, Stott DJ, Buckley BM, Sattar N, Ford I, Westendorp RG, Jukema JW
Background: Statin therapy is widely used in the prevention and treatment of cardiovascular events and is associated with significant risk reductions. However, there is considerable variation in response to statin therapy both in terms of LDL cholesterol reduction and clinical outcomes. It has been hypothesized that genetic variation contributes importantly to this individual drug response. Methods and results: We investigated the interaction between genetic variants and pravastatin or placebo t... Abstract
Cited 4 times since 2014 (0.4 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 101, Issue 1, 23 4 2014, Pages 72-81 Advanced techniques in dobutamine stress echocardiography: focus on myocardial deformation analysis. Joyce E, Delgado V, Bax JJ, Marsan NA
Cited 93 times since 2014 (8.4 per year) source: EuropePMC
BioMed research international, Volume 2014, 23 4 2014, Pages 893106 The multifaceted functions of CXCL10 in cardiovascular disease. van den Borne P, Quax PH, Hoefer IE, Pasterkamp G
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothelial and vascular smooth muscle cells. CXCL10 is secreted by leukocytes and tissue cells and functions as a chemoattractant, mainly for lymphocytes. After binding to its receptor CXCR3, CXCL10 evokes a range of inflammatory responses: key features in cardiovascular disease (CVD).... Abstract
Cited 12 times since 2014 (1.1 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 47, Issue 2, 17 3 2014, Pages 348-54; discussion 354 Valve-sparing aortic root replacement†. Koolbergen DR, Manshanden JS, Bouma BJ, Blom NA, Mulder BJ, de Mol BA, Hazekamp MG
Objectives: To evaluate our results of valve-sparing aortic root replacement and associated (multiple) valve repair. Methods: From September 2003 to September 2013, 97 patients had valve-sparing aortic root replacement procedures. Patient records and preoperative, postoperative and recent echocardiograms were reviewed. Median age was 40.3 (range: 13.4-68.6) years and 67 (69.1%) were male. Seven (7.2%) patients were younger than 18 years, the youngest being 13.4 years. Fifty-four (55.7%) had Marf... Abstract
Expert review of cardiovascular therapy, Volume 12, Issue 7, 16 3 2014, Pages 787-789 Primary prevention implantable cardioverter-defibrillator implantation in elderly patients: is it justified to withhold treatment? van der Heijden AC, van Erven L, Schalij MJ, Borleffs CJ
Implementation of primary prevention implantable cardioverter-defibrillator (ICD) treatment in the current clinical guidelines led to a significant increase in patients that may benefit from implantation of an ICD. Currently non-guideline-guided patient selection takes place by physicians whereby patients at higher age are more frequently excluded for ICD implantation. This editorial focuses on ICD treatment in the elderly and aims to clarify whether it is justified to withhold ICD treatment in... Abstract
Cited 19 times since 2014 (1.7 per year) source: EuropePMC
European journal of trauma and emergency surgery : official publication of the European Trauma Society, Volume 40, Issue 4, 15 3 2014, Pages 421-428 Challenges in the training of military surgeons: experiences from Dutch combat operations in southern Afghanistan. Hoencamp R, Tan EC, Idenburg F, Ramasamy A, van Egmond T, Leenen LP, Hamming JF
Background: To improve care for battle casualties, we analyzed the surgical workload during the Dutch deployment to Uruzgan, Afghanistan. This surgical workload was compared with the resident surgical training and the pre-deployment medical specialist program. Methods: Patient data from the trauma registry (2006-2010) at the Dutch Role 2 Medical Treatment Facility (MTF) were analyzed. The case logs of chief residents (n = 15) from the general surgery training program in the Netherlands were used... Abstract
Cited 4 times since 2014 (0.4 per year) source: EuropePMC
Mediators of inflammation, Volume 2014, 6 1 2014, Pages 395278 Danger signals in cardiovascular disease. Frantz S, Monaco C, Arslan F
Cited 53 times since 2014 (4.8 per year) source: EuropePMC
American heart journal, Volume 168, Issue 1, 4 1 2014, Pages 45-52.e7 A metabolomic profile is associated with the risk of incident coronary heart disease. Vaarhorst AA, Verhoeven A, Weller CM, Böhringer S, Göraler S, Meissner A, Deelder AM, Henneman P, Gorgels AP, van den Brandt PA, Schouten LJ, van Greevenbroek MM, Merry AH, Verschuren WM, van den Maagdenberg AM, van Dijk KW, Isaacs A, Boomsma D, Oostra BA, van Duijn CM, Jukema JW, Boer JM, Feskens E, Heijmans BT, Slagboom PE
Background: Metabolomics, defined as the comprehensive identification and quantification of low-molecular-weight metabolites to be found in a biological sample, has been put forward as a potential tool for classifying individuals according to their risk of coronary heart disease (CHD). Here, we investigated whether a single-point blood measurement of the metabolome is associated with and predictive for the risk of CHD. Methods and results: We obtained proton nuclear magnetic resonance spectra in... Abstract
Cited 3 times since 2014 (0.3 per year) source: EuropePMC
Heart, lung & circulation, Volume 23, Issue 8, 2 1 2014, Pages e169-71 Transcatheter mitral valve repair in osteogenesis imperfecta associated mitral valve regurgitation. van der Kley F, Delgado V, Ajmone Marsan N, Schalij MJ
Objectives: Osteogenesis imperfecta is associated with increased prevalence of significant mitral valve regurgitation. Surgical mitral valve repair and replacement are feasible but are associated with increased risk of bleeding and dehiscence of implanted valves may occur more frequently. The present case report describes the outcomes of transcatheter mitral valve repair in a patient with osteogenesis imperfecta. Patients/methods: A 60 year-old patient with osteogenesis imperfecta and associated... Abstract
Cited 1 times since 2014 (0.1 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 21, Issue 2, 1 1 2014, Pages 245-247 The importance of heart rate response during myocardial perfusion imaging. Bax JJ, Delgado V
Cited 29 times since 2014 (2.6 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 16 Suppl 1, 1 1 2014, Pages i1-78 Statistics on the use of cardiac electronic devices and electrophysiological procedures in 55 ESC countries: 2013 report from the European Heart Rhythm Association (EHRA). Arribas F, Auricchio A, Boriani G, Brugada J, Deharo JC, Hindriks G, Kuck KH, Merino JL, Vardas P, Wolpert C, Zeppenfeld K