Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6173 results
Cited 1 times since 2005 (0.1 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 65, Issue 4, 1 1 2005, Pages 478-483 Early administration of abciximab in patients with acute myocardial infarction improves angiographic and clinical outcome after primary angioplasty. Beeres SL, Oemrawsingh PV, Warda HM, Bechan R, Atsma DE, Jukema JW, van der Wall EE, Schalij MJ
Adjunctive use of abciximab during percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) improves clinical outcome. This study addresses the outcome of patients with AMI treated with abciximab, initiated either before transport to a PCI center (early group) or immediately upon arrival at the catheterization laboratory (late group) for primary PCI. Of 446 consecutive patients with AMI, angiographic data and clinical complications were evaluated up to 6 months after primar... Abstract
Cited 5 times since 2005 (0.3 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 1, Issue 2, 1 1 2005, Pages 236-243 Inhibition of intimal hyperplasia by the tetracycline derived mmp inhibitor doxycycline in vein graft disease in vitro and in vivo. Lardenoye JH, de Vries MR, Deckers M, van Lent N, Hanemaaijer R, van Bockel JH, Quax PH
Aims: Intimal hyperplasia, characterised by smooth muscle cell migration and proliferation, requires extracellular matrix degradation which is mediated by matrix metalloproteinases (MMPs). In this study, the effect of tetracycline derived doxycycline, a specific MMP inhibitor of both activity and synthesis, on intimal hyperplasia in vitro and in vivo was assessed. Methods and results: Segments of human saphenous veins were cultured for 4 weeks in absence or presence of doxycycline (10microg/ml)... Abstract
Cited 42 times since 2005 (2.1 per year) source: EuropePMC
Human molecular genetics, Volume 14, Issue 18, 27 4 2005, Pages 2607-2618 Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study. Frisdal E, Klerkx AH, Le Goff W, Tanck MW, Lagarde JP, Jukema JW, Kastelein JJ, Chapman MJ, Guerin M
Cholesteryl ester transfer protein (CETP) plays a key role in the determination of high-density lipoprotein (HDL) levels via its action on intravascular HDL metabolism. The TaqIB polymorphism of the CETP gene is associated with plasma CETP and high-density lipoprotein cholesterol (HDL-C) levels and with premature coronary artery disease. Such associations appear to result from linkage disequilibrium between TaqIB and other functional polymorphisms. To date, only one functional promoter variant,... Abstract
Cited 16 times since 2005 (0.8 per year) source: EuropePMC
Cardiovascular research, Volume 68, Issue 3, 15 3 2005, Pages 415-424 Histopathologic alterations following local delivery of dexamethasone to inhibit restenosis in murine arteries. Pires NM, Schepers A, van der Hoeven BL, de Vries MR, Boesten LS, Jukema JW, Quax PH
Objective: Dexamethasone-eluting stents are currently under evaluation to prevent post-angioplasty restenosis. The efficacy and safety of dexamethasone as an anti-restenotic agent is still unclear. We assess the effect of perivascular delivery of dexamethasone on vascular pathology in a mouse model of restenosis. Methods and results: In this study we investigate the ability of both systemic and local dexamethasone treatment to inhibit neointima formation after cuff placement around C57BL/6 mouse... Abstract
Cited 39 times since 2005 (2 per year) source: EuropePMC
Diabetes care, Volume 28, Issue 7, 1 1 2005, Pages 1668-1674 The effect of statin therapy on endothelial function in type 2 diabetes without manifest cardiovascular disease. Beishuizen ED, Tamsma JT, Jukema JW, van de Ree MA, van der Vijver JC, Meinders AE, Huisman MV
Objective: Cardiovascular disease (CVD) is the most important cause of mortality in patients with type 2 diabetes and is preceded by endothelial dysfunction. Flow-mediated dilation (FMD) is a noninvasive technique for measuring endothelial dysfunction. We aimed to determine the effect of long-term statin therapy versus placebo on FMD in patients with type 2 diabetes without manifest CVD. Research design and methods: A randomized, placebo-controlled, double-blind trial was performed with 250 type... Abstract
Cited 11 times since 2005 (0.6 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 130, Issue 1, 1 1 2005, Pages 33-40 Acute hemodynamic effects of restrictive mitral annuloplasty in patients with end-stage heart failure: analysis by pressure-volume relations. Tulner SA, Steendijk P, Klautz RJ, Bax JJ, Versteegh MI, van der Wall EE, Dion RA
Objective: Recent studies show beneficial long-term effects of restrictive mitral annuloplasty in patients with end-stage heart failure. However, concerns are raised about possible adverse effects on early postoperative systolic and diastolic function, which might limit application of this approach in patients with heart failure. Therefore we evaluated the acute effects of restrictive mitral annuloplasty on left ventricular function by using load-independent pressure-volume relations. Methods: I... Abstract
Cited 8 times since 2005 (0.4 per year) source: EuropePMC
Diabetes care, Volume 28, Issue 7, 1 1 2005, Pages 1675-1679 No effect of statin therapy on silent myocardial ischemia in patients with type 2 diabetes without manifest cardiovascular disease. Beishuizen ED, Jukema JW, Tamsma JT, van de Ree MA, van der Vijver JC, Putter H, Maan AC, Meinders AE, Huisman MV
Objective: Coronary artery disease is the most important cause of mortality in patients with type 2 diabetes. We aimed to determine the prevalence of silent myocardial ischemia (SMI) and the effect of statin therapy on SMI in type 2 diabetic patients without manifest cardiovascular disease. Research design and methods: A randomized, placebo-controlled, double-blind trial was performed in 250 patients with type 2 diabetes without manifest cardiovascular disease. Patients were given either 0.4 mg... Abstract
Cited 17 times since 2005 (0.9 per year) source: EuropePMC
The American journal of cardiology, Volume 96, Issue 1, 1 1 2005, Pages 22-24 Effect of intracoronary aqueous oxygen on left ventricular remodeling after anterior wall ST-elevation acute myocardial infarction. Warda HM, Bax JJ, Bosch JG, Atsma DE, Jukema JW, van der Wall EE, van der Laarse A, Schalij MJ, Oemrawsingh PV
The present report describes outcomes of randomized selective intracoronary aqueous oxygen versus standard care in patients who had acute anterior wall myocardial infarction within 6 hours of onset (n = 50). Left ventricular (LV) dimensions and function were assessed by contrast echocardiography at baseline and 1 month. It is demonstrated that aqueous oxygen prevents LV remodeling and preserves LV ejection fraction. Abstract
Cited 1 times since 2005 (0.1 per year) source: EuropePMC
Haemophilia : the official journal of the World Federation of Hemophilia, Volume 11, Issue 4, 1 1 2005, Pages 366-370 The effect of clotting factor concentrates on the immune system in HIV-negative haemophilics. Balkan C, Kavakli K, Kutukculer N, Aksu G, Yilmaz D, Aydinok Y
Immune abnormalities have been reported in patients with haemophilia. Although infections with HIV and hepatitis viruses contribute to these abnormalities, chronic exposure to extraneous proteins in clotting factor concentrates (CFC) may also play a role. A number of studies suggest that the degree of immunological abnormalities correlates with the amount of intermediate purity CFC administered over time. The purpose of this study was to investigate whether there were cellular and humoral immuno... Abstract
Cited 30 times since 2005 (1.5 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 46, Issue 1, 1 1 2005, Pages 15-20 Sustained benefit 20 years after reperfusion therapy in acute myocardial infarction. van Domburg RT, Sonnenschein K, Nieuwlaat R, Kamp O, Storm CJ, Bax JJ, Simoons ML
Objectives: The goal of this research was to clarify whether the benefit of reperfusion therapy for myocardial infarction was sustained long-term and to assess the gain in life expectancy by reperfusion therapy. Background: Reperfusion therapy in acute myocardial infarction reduces infarct size and increases hospital survival. Methods: We analyzed the 20-year outcome of 533 patients (mean age 56 years; 82% men) who were randomized to either reperfusion therapy or conventional therapy during the... Abstract
Cited 8 times since 2005 (0.4 per year) source: EuropePMC
Journal of hypertension, Volume 23, Issue 7, 1 1 2005, Pages 1409-1415 Simultaneous echocardiography and myocardial perfusion single photon emission computed tomography associated with dobutamine stress to predict long-term cardiac mortality in normotensive and hypertensive patients. Bigi R, Bax JJ, van Domburg RT, Elhendy A, Cortigiani L, Schinkel AF, Fiorentini C, Poldermans D
Background: Echocardiography and myocardial scintigraphy associated with dobutamine stress are used for assessing risk in coronary artery disease. We compared the accuracy of the two modalities applied simultaneously for predicting long-term cardiac mortality in normotensive and hypertensive patients. Methods: Three hundred and fifty-one consecutive patients underwent dobutamine stress with simultaneous echocardiography and Tc-sestamibi single photon emission computed tomography (SPECT). Fifty p... Abstract
Cited 1 times since 2005 (0.1 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 32, Issue 7, 1 1 2005, Pages 829-831 FDG imaging should be considered the preferred technique for accurate assessment of myocardial viability: for. Bax JJ
Cited 28 times since 2005 (1.4 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 16, Issue 7, 1 1 2005, Pages 701-707 Long-term follow-up of cardiac resynchronization therapy in patients with end-stage heart failure. Molhoek SG, Bax JJ, Bleeker GB, Holman ER, Van Erven L, Bootsma M, Boersma E, Steendijk P, Van Der Wall EE, Schalij MJ
Unlabelled: Long-term follow-up of cardiac resynchronization therapy. Introduction: Cardiac resynchronization therapy (CRT) has been introduced to treat patients with end-stage heart failure, and results of this technique are promising. The aim of our study was to assess the sustained benefit of CRT in a large patient cohort with end-stage heart failure at long-term follow-up. In addition, the prognosis of responders and nonresponders was evaluated. Methods and results: 125 patients with end-sta... Abstract
Future cardiology, Volume 1, Issue 4, 1 1 2005, Pages 479-488 The role of insulin-like growth factor during a postischemic period - new insights into pathophysiologic pathways in cardiac tissue. Palmen M, Twickler MT, Daemen MJ, Cramer MJ, Doevendans PA
Despite an improvement in the therapeutic strategies available for an acute ischemic event, cardiac disease is still the principal cause of morbidity and mortality in Western societies. A shift from acute towards more chronic heart disease due to atherosclerotic disease has been recognized. Modification of adaptive capacities of the cardiac muscle after damage remains a key component in the prevention of chronic cardiac disease, such as overt heart failure. It has recently been demonstrated that... Abstract
Cited 28 times since 2005 (1.4 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 91, Issue 7, 1 1 2005, Pages 981-990 Clinical applications of intracardiac echocardiography in interventional procedures. Jongbloed MR, Schalij MJ, Zeppenfeld K, Oemrawsingh PV, van der Wall EE, Bax JJ
Cited 17 times since 2005 (0.9 per year) source: EuropePMC
The American journal of cardiology, Volume 96, Issue 1, 1 1 2005, Pages 108-111 Comparison of effectiveness of cardiac resynchronization therapy in patients with versus without diabetes mellitus. Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Boersma E, Steendijk P, van der Wall EE, Schalij MJ
The effect of long-term cardiac resynchronization therapy (CRT) was evaluated in 32 patients with heart failure (HF) and diabetes mellitus (DM) compared with 65 patients with HF and no DM. Clinical parameters were obtained before and after 6 months of CRT. Long-term follow-up was performed Abstract
Cited 24 times since 2005 (1.2 per year) source: EuropePMC
Pediatric research, Volume 58, Issue 1, 27 4 2005, Pages 46-52 Neonatal glucocorticosteroid treatment causes systolic dysfunction and compensatory dilation in early life: studies in 4-week-old prepubertal rats. Bal MP, de Vries WB, van der Leij FR, van Oosterhout MF, Berger RM, Baan J, van der Wall EE, van Bel F, Steendijk P
Glucocorticosteroid treatment is widely used to prevent chronic lung disease in premature infants. Recent studies in adult rats, treated with dexamethasone in the neonatal period, report negative long-term effects on the heart and severely reduced life expectancy. We treated neonatal rats with dexamethasone and studied cardiac function after 4 wk (prepubertal age) to investigate whether the late effects as previously described are preceded by detectable alterations in cardiac function at a young... Abstract
Cited 35 times since 2005 (1.8 per year) source: EuropePMC
Medical engineering & physics, Volume 28, Issue 3, 24 4 2005, Pages 199-213 Effects of different inter-implant distances on the stress distribution around endosseous implants in posterior mandible: a 3D finite element analysis. Simşek B, Erkmen E, Yilmaz D, Eser A
Purpose: The aim of this study was to evaluate the effects of different inter-implant distances on stress distribution in the bone around the endosseous titanium implants under vertical, oblique and horizontal loads in the posterior mandibular edentulousim by finite element analysis (3D FEA). Materials and methods: 3D FEA models representing mandible and ITI implant (Straumann, Waldenburg, Switzerland) were simulated. The distances in-between the units were set at 0.5, 1.0 and 2.0 cm. Vertical (... Abstract
Cited 23 times since 2005 (1.2 per year) source: EuropePMC
Clinical science (London, England : 1979), Volume 108, Issue 6, 1 1 2005, Pages 539-545 Genetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7alpha-hydroxylase) influences the progression of atherosclerosis and risk of new clinical events. Hofman MK, Princen HM, Zwinderman AH, Jukema JW
CHD (coronary heart disease) is a complex disorder which is, in part, related to serum cholesterol levels. The rate-limiting enzyme in the catabolism of cholesterol into bile acids is CYP7A1 (cholesterol 7alpha-hydroxylase). The effect of the CYP7A1 A-278C promoter polymorphism on the progression of atherosclerosis, risk of a new clinical event and the influence of this variant on cholesterol-lowering therapy was investigated in 715 male patients with coronary atherosclerosis participating in RE... Abstract
Cited 34 times since 2005 (1.7 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 27, Issue 6, 1 1 2005, Pages 975-979 Results of the Ross operation in a pediatric population. Hazekamp MG, Grotenhuis HB, Schoof PH, Rijlaarsdam ME, Ottenkamp J, Dion RA
Objective: To analyse the results of the mid-term clinical and echocardiographic follow-up of the pediatric Ross operation. Methods: Echo-Doppler follow-up of 53 consecutive pediatric Ross procedures performed between 1994 and 2003. Median age was 9.7 years at time of operation (2 weeks-17.7 years). Six patients were younger than 3 months. Median age at follow-up was 15.6 years. Aortic valve/left ventricular outflow tract (LVOT) anomalies were congenital in 49 (92%). Seventy percent had previous... Abstract