Research

Publications

Below you can find a list of our published research.

6190 results

Cited 19 times since 1993 (0.6 per year) source: EuropePMC

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 7, Issue 10, 1 1 1993, Pages 514-519 The value of the stentless biovalve prosthesis. An experimental study. Hazekamp MG, Goffin YA, Huysmans HA

Clinical use of the stentless bioprosthesis has not yet been accepted world-wide. Experimental studies are scarce. In a study in growing pigs, 23 aortic valve replacements were performed (7 stented bioprostheses (STB), 10 stentless bioprostheses (SLB) and 6 cryopreserved homografts (CAH)). Valves were studied macroscopically and microscopically after explantation. Five animals died between 1.5 and 4 months after implantation. Two STBs showed extreme calcific degeneration. A third STB animal died... Abstract

Cited 15 times since 1993 (0.5 per year) source: EuropePMC

The Anatomical record, Volume 235, Issue 1, 1 1 1993, Pages 74-86 Histological organization of the right and left atrioventricular valves of the chicken heart and their relationship to the atrioventricular Purkinje ring and the middle bundle branch. Lu Y, James TN, Bootsma M, Terasaki F

In the avian heart the right and left atrioventricular (AV) valves not only exhibit their own special anatomical characteristics, but they also are in close proximity to the conduction system. The right AV valve is a single, spiral plane of myocardium, in remarkable contrast to the fibrous structure characteristic of the mammalian tricuspid valve. A ring of Purkinje tissue encircles the avian right AV orifice and connects to the muscular valve. The chicken has no crista supraventricularis, its r... Abstract

Cited 16 times since 1993 (0.5 per year) source: EuropePMC

Magnetic resonance imaging, Volume 11, Issue 2, 1 1 1993, Pages 207-218 Sequential analysis of infarcted and normal myocardium in piglets using in vivo gadolinium-enhanced MR images. van Dijkman PR, Höld KM, van der Laarse A, Holman ER, Ozdemir HI, van der Nat TH, de Roos A, van der Wall EE

Gadolinium-enhanced magnetic resonance (MR) imaging was performed before, and 1 and 3 wk after coronary occlusion in domestic piglets. After administration of the contrast agent gadopentetate dimeglumine, two different enhancement patterns within the infarcted region were observed. The first pattern, showing peripheral enhancement of the infarcted region with absence of contrast in the center, was seen at 1 wk after occlusion at 5 min after administration of the contrast agent. The second patter... Abstract

Nederlands tijdschrift voor geneeskunde, Volume 137, Issue 2, 1 1 1993, Pages 75-80 [The value of cytological studies in nodular goiter: results in 495 patients]. Goslings BM, Smak Gregoor PJ, Samrén EB, Hamming JF, van Steenis GJ, Hermans J

The accuracy of clinical diagnosis and fine-needle aspiration biopsy (FNAB) was evaluated in a total of 495 patients of whom 183 were operated upon within 6 months after FNAB and 312 were not. Operated patients were divided into three subgroups with high, moderate or low suspicion of malignant neoplasms on clinical grounds. Histological examination revealed an overall malignant neoplasm rate of 23%. The rate, i.e. the positive predictive value, was 74% for the subgroup with high clinical suspici... Abstract

Cited 17 times since 1993 (0.5 per year) source: EuropePMC

Invasion & metastasis, Volume 13, Issue 6, 1 1 1993, Pages 277-288 Increased urokinase receptor levels in human gastrointestinal neoplasia and related liver metastases. Sier CF, Quax PH, Vloedgraven HJ, Verheijen JH, Griffioen G, Ganesh S, Lamers CB, Verspaget HW

Human carcinomas of the oesophagus, stomach, colorectum, and their liver metastases were previously shown to have increased levels of the urokinase-type plasminogen activator (u-PA). The proteolytic activity of u-PA on the surface of tumour cells is thought to play a key role in invasion and metastasis of malignancies. Therefore, in this study we quantitatively determined the presence of specific u-PA receptors in human gastrointestinal carcinomas, premalignant colonic adenomas, liver metastases... Abstract

Cited 26 times since 1993 (0.8 per year) source: EuropePMC

European heart journal, Volume 14, Issue 1, 1 1 1993, Pages 53-56 Dipyridamole thallium-201 scintigraphy for improved detection of left anterior descending coronary artery stenosis in patients with left bundle branch block. Jukema JW, van der Wall EE, van der Vis-Melsen MJ, Kruyswijk HH, Bruschke AV

In patients with left bundle branch block (LBBB) undergoing thallium-201 exercise scintigraphy septal perfusion defects are frequently observed irrespective of the presence or absence of coronary artery disease. Consequently, in these patients the specificity for detecting stenoses in the left anterior descending coronary artery (LAD) by thallium-201 scintigraphy is relatively low. It has been hypothesized that pharmacological vasodilation would result in higher specificity than conventional exe... Abstract

Cited 6 times since 1993 (0.2 per year) source: EuropePMC

Arteriosclerosis and thrombosis : a journal of vascular biology, Volume 13, Issue 1, 1 1 1993, Pages 78-83 Potential of 99mTc-LDLs labeled by two different methods for scintigraphic detection of experimental atherosclerosis in rabbits. Atsma DE, Feitsma RI, Camps J, van't Hooft FM, van der Wall EE, Nieuwenhuizen W, Pauwels EK

In this study we evaluated two different 99mTc-labeling techniques to produce 99mTc-low density lipoprotein (99mTc-LDL) suitable for the scintigraphic delineation of experimental atherosclerotic lesions. The two methods are 1) a procedure that uses stannous chloride and sodium borohydride (borohydride method) and 2) a procedure that uses sodium dithionite as a reducing agent and that has been successfully applied in previous scintigraphic atherosclerosis detection (dithionite method). 99mTc-LDL... Abstract

Clinical nutrition (Edinburgh, Scotland), Volume 11, Issue 6, 1 1 1992, Pages 376 Correspondence. Verbeek MJ, van der Heijden A, Schreurs VV, Akkermans LM, Vos A

Abstract

Cited 140 times since 1992 (4.3 per year) source: EuropePMC

Journal of virology, Volume 66, Issue 11, 1 1 1992, Pages 6294-6303 Structural proteins of equine arteritis virus. de Vries AA, Chirnside ED, Horzinek MC, Rottier PJ

We have recently shown that the genome of equine arteritis virus (EAV) contains seven open reading frames (ORFs). We now present data on the structural proteins of EAV and the assignment of their respective genes. Virions are composed of a 14-kDa nucleocapsid protein (N) and three membrane proteins designated M, GS, and GL. M is an unglycosylated protein of 16 kDa, and GS and GL are N-glycosylated proteins of 25 and 30 to 42 kDa, respectively. The broad size distribution of GL results from heter... Abstract

Cited 14 times since 1992 (0.4 per year) source: EuropePMC

European heart journal, Volume 13 Suppl E, 1 1 1992, Pages 28-34 Single and dual excitation of the conductance-volume catheter analysed in a spheroidal mathematical model of the canine left ventricle. Steendijk P, van der Velde ET, Baan J

The conductance method employs a multi-electrode catheter to generate an electrical field and measure intracavitary segmental conductances. Left ventricular (LV) volumes are calculated using an algorithm which assumes the electrical field to be homogeneous. This assumption may be violated leading to a non-linear relation between conductance-derived and true volumes. In addition, this relation may vary between segments. A new method is introduced which uses a more homogeneous field. Volume estima... Abstract

Cited 49 times since 1992 (1.5 per year) source: EuropePMC

The American journal of physiology, Volume 263, Issue 5 Pt 2, 1 1 1992, Pages H1466-78 Anisotropic conduction and reentry in perfused epicardium of rabbit left ventricle. Schalij MJ, Lammers WJ, Rensma PL, Allessie MA

An experimental model of anisotropy was developed, consisting of a thin layer (1 mm) of perfused ventricular epicardium created by cryodestruction of the interventricular septum and the inner four-fifths of the free wall of the left ventricle. The electrophysiological properties of the 1-mm-thick surviving layer were the same as before freezing. Epicardial conduction was mapped with a 192-fold mapping electrode (spatial resolution 1 mm). In the intact ventricle transverse conduction was interrup... Abstract

Cited 31 times since 1992 (1 per year) source: EuropePMC

European heart journal, Volume 13 Suppl E, 1 1 1992, Pages 2-6 Ventricular pressure-volume relations in vivo. Baan J, van der Velde ET, Steendijk P

A number of fundamental mechanical properties of cardiac muscle as well as of the total ventricle are discussed. These include: Starling's law, shortening deactivation, homeometric autoregulation, and so-called hyperactivation associated with a small amount of ejection. Whenever appropriate, muscle properties are related to those of the intact ventricle. The phenomenon of load-dependence of the end-systolic pressure-volume relationship (ESPVR) receives particular attention and is placed wit... Abstract

Cited 11 times since 1992 (0.3 per year) source: EuropePMC

Journal of vascular research, Volume 29, Issue 6, 1 1 1992, Pages 426-434 Thrombogenicity and intimal hyperplasia after conventional and thermal balloon dilation in normal rabbit iliac arteries. van Erven L, Velema E, Bos AN, Post MJ, Borst C

Acute occlusion and restenosis are the major complications of percutaneous transluminal coronary balloon angioplasty. Application of heat during balloon dilation was postulated to reduce these complications. We evaluated thrombogenicity and intimal hyperplasia of normal rabbit iliac arteries after conventional (37 degrees C) and thermal balloon dilation. Thermal dilation was performed with a radio-frequency-heated balloon, provided with three thermocouples attached to the inside of the balloon s... Abstract

Cited 7 times since 1992 (0.2 per year) source: EuropePMC

European heart journal, Volume 13 Suppl E, 1 1 1992, Pages 15-21 Left ventricular segmental volume by conductance catheter and Cine-CT. van der Velde ET, van Dijk AD, Steendijk P, Diethelm L, Chagas T, Lipton MJ, Glanz SA, Baan J

The ability of the conductance catheter method to measure left ventricular segmental and total volume was evaluated by comparison with the Cine-CT technique. In the seven dogs studied, 19 conductance catheter and simultaneous Cine-CT runs were obtained. High correlation coefficients were found for total volume and segmental volumes, except in the basal segment. However, in most cases there was a significant variability in slope and intercept between animals. Both methods are promising tools for... Abstract

Cited 2 times since 1992 (0.1 per year) source: EuropePMC

Der Urologe. Ausg. A, Volume 31, Issue 6, 1 1 1992, Pages 378-383 [Obstructive uropathy after kidney transplantation. Experiences with endourologic incision of ureteral stenoses]. Schneider AW, Meyer-Moldenhauer WH, Conrad S, Otto U, Klosterhalfen H

Between 1985 und March 1991 we have managed 8 upper urinary tract obstructions in kidney transplants using an endourological approach. After a graft rejection was excluded an obstruction was initially diagnosed by nephrosonography and further confirmed by IVP or antegrade pyelography. To investigate the urodynamic relevance of the stenosis, all patients underwent preoperative diuretic isotope renography. In all cases a percutaneous pyelostomy was done to preserve renal function. 7 of these 8 pat... Abstract

Cited 8 times since 1992 (0.2 per year) source: EuropePMC

European heart journal, Volume 13 Suppl E, 1 1 1992, Pages 40-46 The end-systolic pressure-volume relationship in young animals using the conductance technique. Teitel DF, Klautz RJ, Cassidy SC, Steendijk P, van der Velde ET, van Bel F, Baan J

Evaluation of ventricular performance by the end-systolic pressure-volume relationship (ESPVR) has been extensively performed in the adult heart using the conductance technique. We undertook this study to validate the conductance technique and to generate ESPVRs in the small heart. To validate the technique, we simultaneously measured left ventricular volume by the conductance catheter and biplane cineangiography in nine piglets during changes in volume and contractility. Raw conductance volumes... Abstract

Cited 19 times since 1992 (0.6 per year) source: EuropePMC

American heart journal, Volume 124, Issue 5, 1 1 1992, Pages 1397-1399 Pseudoaneurysm of a saphenous vein coronary artery bypass graft with a fistula draining into the right atrium. Jukema JW, van Dijkman PR, van der Wall EE

Abstract

Cited 3 times since 1992 (0.1 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 104, Issue 4, 1 1 1992, Pages 1053-1059 Mid-infrared pulsed laser ablation of the arterial wall. Mechanical origin of "acoustic" wall damage and its effect on wall healing. van Erven L, van Leeuwen TG, Post MJ, van der Veen MJ, Velema E, Borst C

Pulsed mid-infrared lasers are an alternative to excimer lasers for transluminal angioplasty. The mid-infrared lasers, however, were reported to produce "acoustic" wall damage that might impair the immediate and long-term results. To study the immediate and long-term effects on the arterial wall, 184 craters (1 mm diameter and 1 mm depth) were produced perpendicular to the intimal lining in the thoracic aortas of pigs. Three types of craters were evaluated: Ho-YSGG laser-induced (lambd... Abstract

Cited 32 times since 1992 (1 per year) source: EuropePMC

Circulation research, Volume 71, Issue 2, 1 1 1992, Pages 385-392 Cultured rat aortic vascular smooth muscle cells digest naturally produced extracellular matrix. Involvement of plasminogen-dependent and plasminogen-independent pathways. Sperti G, van Leeuwen RT, Quax PH, Maseri A, Kluft C

Vascular smooth muscle (VSM) cell migration and proliferation play a major role in the development of atherosclerotic lesions, graft occlusion, and restenosis after angioplasty. Cell migration implies the digestion of the surrounding extracellular matrix. Cell-associated proteolysis has been extensively studied in neoplastic and inflammatory cells, but very little is known about the proteolytic properties of VSM. We have evaluated the ability of rat cultured VSM cells to solubilize [3H]amino aci... Abstract

Cited 70 times since 1992 (2.1 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 19, Issue 7, 1 1 1992, Pages 1610-1618 Origin of arterial wall dissections induced by pulsed excimer and mid-infrared laser ablation in the pig. van Leeuwen TG, van Erven L, Meertens JH, Motamedi M, Post MJ, Borst C

To study adjacent tissue damage after delivery of holmium, thulium and excimer laser pulses, porcine thoracic aortas were irradiated in vivo. After 3 days, microscopic analysis of 67 craters produced by all three lasers demonstrated large dissections extending from the craters. The mean diameter of the dissections was smaller for excimer-induced craters (1.38 +/- 0.42 mm; n = 22) than for holmium-induced (2.7 +/- 0.87 mm; n = 22) and thulium-induced (2.37 +/- 0.42 mm; n = 14) craters (p less tha... Abstract