8899 results
Cited 102 times since 2024 (69.3 per year)
source: EuropePMC
The New England journal of medicine,
Volume 390, Issue 19, 1 1 2024, Pages 1745-1755
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage.
Connolly SJ, Sharma M, Cohen AT, Demchuk AM, Członkowska A, Lindgren AG, Molina CA, Bereczki D, Toni D, Seiffge DJ, Tanne D, Sandset EC, Tsivgoulis G, Christensen H, Beyer-Westendorf J, Coutinho JM, Crowther M, Verhamme P, Amarenco P, Roine RO, Mikulik R, Lemmens R, Veltkamp R, Middeldorp S, Robinson TG, Milling TJ, Tedim-Cruz V, Lang W, Himmelmann A, Ladenvall P, Knutsson M, Ekholm E, Law A, Taylor A, Karyakina T, Xu L, Tsiplova K, Poli S, Kallmünzer B, Gumbinger C, Shoamanesh A, ANNEXA-I Investigators
Background: Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied. Methods: We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage to receive andexanet or usual care. The primary end point was hemost...
Abstract
Cited 5 times since 2024 (3.4 per year)
source: EuropePMC
Human reproduction (Oxford, England),
Volume 39, Issue 5, 1 1 2024, Pages 912-922
First trimester maternal tryptophan metabolism and embryonic and fetal growth: the Rotterdam Periconceptional Cohort (Predict Study).
van Zundert SKM, van Egmond NCM, van Rossem L, Willemsen SP, Griffioen PH, van Schaik RHN, Mirzaian M, Steegers-Theunissen RPM
Study question: What is the association between first trimester maternal tryptophan (TRP) metabolites and embryonic and fetal growth? Summary answer: Higher 5-hydroxytryptophan (5-HTP) concentrations are associated with reduced embryonic growth and fetal growth and with an increased risk of small-for-gestational age (SGA), while higher kynurenine (KYN) concentrations are associated with a reduced risk of SGA. What is known already: The maternal TRP metabolism is involved in many critical process...
Abstract
Cited 2 times since 2024 (1.4 per year)
source: EuropePMC
Clinical chemistry,
Volume 70, Issue 5, 1 1 2024, Pages 759-767
External Quality Assessment on Molecular Tumor Profiling with Circulating Tumor DNA-Based Methodologies Routinely Used in Clinical Pathology within the COIN Consortium.
van der Leest P, Rozendal P, Hinrichs J, van Noesel CJM, Zwaenepoel K, Deiman B, Huijsmans CJJ, van Eijk R, Speel EJM, van Haastert RJ, Ligtenberg MJL, van Schaik RHN, Jansen MPHM, Dubbink HJ, de Leng WW, Leers MPG, Tamminga M, van den Broek D, van Kempen LC, Schuuring E
Background: Identification of tumor-derived variants in circulating tumor DNA (ctDNA) has potential as a sensitive and reliable surrogate for tumor tissue-based routine diagnostic testing. However, variations in pre(analytical) procedures affect the efficiency of ctDNA recovery. Here, an external quality assessment (EQA) was performed to determine the performance of ctDNA mutation detection work flows that are used in current diagnostic settings across laboratories within the Dutch COIN consorti...
Abstract
Cited 2 times since 2024 (1.4 per year)
source: EuropePMC
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland,
Volume 26, Issue 6, 30 5 2024, Pages 1239-1249
Dissecting the surgeon's personality: cross-cultural comparisons in Western Europe.
Sier VQ, Bisset CN, Tesselaar DAJ, Schmitz RF, Schepers A, Moug SJ, van der Vorst JR, SUPER and Plato Project Collaborators
Aim: The surgeon's personality contributes to variation in surgical decision-making. Previous work on surgeon personality has largely been reserved to Anglo-Saxon studies, with limited international comparisons. In this work we built upon recent work on gastrointestinal surgeon personality and aimed to detect international variations. Method: Gastrointestinal surgeons from the UK and the Netherlands were invited to participate in validated personality assessments (44-item, 60-item Big Five...
Abstract
Cited 88 times since 2024 (59.7 per year)
source: EuropePMC
Nature genetics,
Volume 56, Issue 5, 30 5 2024, Pages 778-791
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, De Borst MH, Polašek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, D
Hypertension affects more than one billion people worldwide. Here we identify 113 novel loci, reporting a total of 2,103 independent genetic signals (P
Abstract
Cited 3 times since 2024 (2 per year)
source: EuropePMC
Journal of cardiovascular medicine (Hagerstown, Md.),
Volume 25, Issue 6, 26 4 2024, Pages 438-449
Coronary calcified nodules versus nonnodular coronary calcifications: a systematic review and meta-analysis.
Oliveri F, Van Oort MJH, Al Amri I, Bingen BO, Van der Kley F, Jukema JW, Jurado-Roman A, Montero Cabezas J
Background: Percutaneous coronary intervention (PCI) on severely calcified coronary lesions is challenging. Coronary calcified nodule (CN) refers to an eccentric and protruding coronary calcification associated with plaque vulnerability and adverse clinical events. This study aims to conduct an extensive review of CNs, focusing on its prognostic impact in comparison with nonnodular coronary calcification (N-CN). Method: A systematic literature review on PubMed, MEDLINE, and EMBASE databases was...
Abstract
Cited 6 times since 2024 (4 per year)
source: EuropePMC
Biological reviews of the Cambridge Philosophical Society,
Volume 99, Issue 5, 26 4 2024, Pages 1638-1651
The forgotten adaptive social benefits of social learning in animals.
Harrison RA, Dongre P, van Schaik CP, van de Waal E
Theoretical and empirical scholars of cultural evolution have traditionally studied social learning strategies, such as conformity, as adaptive strategies to obtain accurate information about the environment, whereas within social psychology there has been a greater focus upon the social consequences of such strategies. Although these two approaches are often used in concert when studying human social learning, we believe the potential social benefits of conformity, and of social learning more b...
Abstract
Coronary artery disease,
Volume 35, Issue 5, 25 4 2024, Pages 405-412
Cardiovascular risk profile in two cohorts of young apparently healthy South Asian descendants in the Netherlands: still a long way to go!
Gobardhan SN, Oemrawsingh PV, Liem SS, Cannegieter SC, Schalij MJ
Background: Cardiovascular disease (CVD) imposes a major healthcare burden on young descendants of South Asian migrants living in the western world. In comparison to the native population, the prevalence is significantly higher and the prevalence of CVD risk factors is increasing rapidly. The cardiovascular risk profile and 10-year risk scores of South Asian descendants were evaluated in two cohorts with a 10-year time difference. Methods: Two cross-sectional studies, conducted in 2004 and 2014,...
Abstract
Cited 1 times since 2024 (0.7 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 18, Issue 4, 24 4 2024, Pages 366-374
Prognostic value of a novel artificial intelligence-based coronary CTA-derived ischemia algorithm among patients with normal or abnormal myocardial perfusion.
Bär S, Maaniitty T, Nabeta T, Bax JJ, Earls JP, Min JK, Saraste A, Knuuti J
Background: Among patients with obstructive coronary artery disease (CAD) on coronary computed tomography angiography (CTA), downstream positron emission tomography (PET) perfusion imaging can be performed to assess the presence of myocardial ischemia. A novel artificial-intelligence-guided quantitative computed tomography ischemia algorithm (AI-QCTischemia) aims to predict ischemia directly from coronary CTA images. We aimed to study the prognostic value of AI-QCTischemia among patients with ob...
Abstract
Cited 1 times since 2024 (0.7 per year)
source: EuropePMC
Annals of gastroenterological surgery,
Volume 8, Issue 6, 22 4 2024, Pages 1008-1016
High risk of multiple gastric cancers in Japanese individuals with Lynch syndrome.
Kanaya N, van Schaik TA, Aoki H, Sato Y, Taniguchi F, Shigeyasu K, Sugano K, Akagi K, Ishida H, Tanakaya K
Aim: Lynch syndrome (LS) is a dominantly inherited syndrome characterized by an increased risk for LS associated tumors such as colorectal cancer (CRC) and gastric cancer (GC). However, the clinical benefit of surveillance for GC remains unclear while it has already been recommended for CRC. This study aimed to elucidate the clinical features of GC in Japanese individuals with LS, and the risk of developing multiple GCs to build regional-tailored surveillance programs in LS patients with GC. Met...
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
Plant direct,
Volume 8, Issue 4, 21 3 2024, Pages e584
Pectin methylesterification state and cell wall mechanical properties contribute to neighbor proximity-induced hypocotyl growth in Arabidopsis.
Sénéchal F, Robinson S, Van Schaik E, Trévisan M, Saxena P, Reinhardt D, Fankhauser C
Plants growing with neighbors compete for light and consequently increase the growth of their vegetative organs to enhance access to sunlight. This response, called shade avoidance syndrome (SAS), involves photoreceptors such as phytochromes as well as phytochrome interacting factors (PIFs), which regulate the expression of growth-mediating genes. Numerous cell wall-related genes belong to the putative targets of PIFs, and the importance of cell wall modifications for enabling growth was extensi...
Abstract
Cited 11 times since 2024 (7.3 per year)
source: EuropePMC
Journal of the American Academy of Dermatology,
Volume 91, Issue 2, 21 3 2024, Pages 300-311
Dupilumab provides sustained effectiveness on patient-reported outcomes and favorable safety in patients with moderate-to-severe atopic dermatitis: Up to 5-year results from the daily practice BioDay registry.
Zhang J, Boesjes CM, Loman L, Kamphuis E, Romeijn MLE, Spekhorst LS, Haeck I, van der Gang LF, Dekkers CC, van der Rijst LP, Oosting AJ, van Lumig P, van Lynden-van Nes AMT, Tupker RA, Nijssen A, Flinterman A, Politiek K, Touwslager WRH, Christoffers WA, Stewart SM, Kamsteeg M, de Graaf M, de Bruin-Weller MS, Schuttelaar MA
Background: Long-term daily practice data on patient-reported benefits of dupilumab for atopic dermatitis (AD) remains limited. Objective: To evaluate patient-reported outcome measures (PROMs) and the safety of dupilumab in patients with moderate-to-severe AD over a follow-up period of up to 5 years. Methods: Data were extracted from the prospective, multicenter BioDay registry (October 2017-2022) of patients with moderate-to-severe AD treated with dupilumab in daily practice. Results: In total...
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
Scientific reports,
Volume 14, Issue 1, 20 3 2024, Pages 9113
The effect of immunosuppressive therapies on the endothelial host response in critically ill COVID-19 patients.
Slim MA, Lim EHT, van Vught LA, Boer AMT, Rademaker E, Mulier JLGH, Engel JJ, Amsterdam UMC COVID-19 Biobank Study Group, Radboudumc Center for Infectious Diseases COVID-19 Study Group, Pickkers P, van de Veerdonk FL, Vlaar APJ, Derde LPG, Juffermans NP
While several effective therapies for critically ill patients with COVID-19 have been identified in large, well-conducted trials, the mechanisms underlying these therapies have not been investigated in depth. Our aim is to investigate the association between various immunosuppressive therapies (corticosteroids, tocilizumab and anakinra) and the change in endothelial host response over time in critically ill COVID-19 patients. We conducted a pre-specified multicenter post-hoc analysis in a Dutch...
Abstract
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
Volume 85, 20 3 2024, Pages 5-7
Exploring P-gp as moderator of side effects and effectiveness of risperidone in children and adolescents.
Hermans RA, Gangapersad RN, Kloosterboer SM, van Schaik RHN, Hillegers MHJ, Koch BCP, de Winter BCM, Dierckx B
Abstract
Cited 3 times since 2024 (2 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 32, Issue 5, 18 3 2024, Pages 190-197
Assessment of ICD eligibility in non-ischaemic cardiomyopathy patients: a position statement by the Task Force of the Dutch Society of Cardiology.
van der Lingen ACJ, Verstraelen TE, van Erven L, Meeder JG, Theuns DA, Vernooy K, Wilde AAM, Maass AH, Allaart CP
International guidelines recommend implantation of an implantable cardioverter-defibrillator (ICD) in non-ischaemic cardiomyopathy (NICM) patients with a left ventricular ejection fraction (LVEF) below 35% despite optimal medical therapy and a life expectancy of more than 1 year with good functional status. We propose refinement of these recommendations in patients with NICM, with careful consideration of additional risk parameters for both arrhythmic and non-arrhythmic death. These additional p...
Abstract
Cited 9 times since 2024 (6 per year)
source: EuropePMC
The Lancet. Respiratory medicine,
Volume 12, Issue 7, 16 3 2024, Pages 513-522
Transbronchial cryobiopsy followed by as-needed surgical lung biopsy versus immediate surgical lung biopsy for diagnosing interstitial lung disease (the COLD study): a randomised controlled trial.
Kalverda KA, Ninaber MK, Wijmans L, von der Thüsen J, Jonkers RE, Daniels JM, Miedema JR, Dickhoff C, Hölters J, Heineman D, Kant M, Radonic T, Shahin G, Cohen D, Boerrigter B, Nijman S, Nossent E, Braun J, Mathot B, Poletti V, Hetzel J, Dijkgraaf M, Korevaar DA, Bonta PI, Annema JT
Background: An adequate diagnosis for interstitial lung disease (ILD) is important for clinical decision making and prognosis. In most patients with ILD, an accurate diagnosis can be made by clinical and radiological data assessment, but in a considerable proportion of patients, a lung biopsy is required. Surgical lung biopsy (SLB) is the most common method to obtain tissue, but it is associated with high morbidity and even mortality. More recently, transbronchial cryobiopsy has been introduced,...
Abstract
PloS one,
Volume 19, Issue 4, 16 3 2024, Pages e0300978
Computer based method for identification of fibrotic scars from electrograms and local activation times on the epi- and endocardial surfaces of the ventricles.
Okenov A, Nezlobinsky T, Zeppenfeld K, Vandersickel N, Panfilov AV
Cardiac fibrosis stands as one of the most critical conditions leading to lethal cardiac arrhythmias. Identifying the precise location of cardiac fibrosis is crucial for planning clinical interventions in patients with various forms of ventricular and atrial arrhythmias. As fibrosis impedes and alters the path of electrical waves, detecting fibrosis in the heart can be achieved through analyzing electrical signals recorded from its surface. In current clinical practices, it has become feasible t...
Abstract
American journal of otolaryngology,
Volume 45, Issue 4, 16 3 2024, Pages 104298
Potential imaging targets in primary head and neck squamous cell carcinoma and lymph node metastases.
van Schaik JE, van der Vegt B, Slagter-Menkema L, Hanemaaijer SH, Halmos GB, Witjes MJH, van der Laan BFAM, Fehrmann RSN, Oosting SF, Plaat BEC
Purpose: To investigate glycoprotein nonmetastatic melanoma protein B (GPNMB) and vascular endothelial growth factor (VEGF) as potential fluorescent imaging markers by comparing their protein expression to epidermal growth factor receptor (EGFR). Materials and methods: Thirty-eight paired samples of untreated head and neck squamous cell carcinoma (HNSCC) primary tumours (PT) and corresponding synchronous lymph node metastases (LNM) were selected. After immunohistochemical staining, expression wa...
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
Clinical research in cardiology : official journal of the German Cardiac Society,
Volume 114, Issue 3, 15 3 2024, Pages 341-349
Safety and feasibility of early discharge after transcatheter aortic valve implantation with ACURATE Neo-the POLESTAR trial.
Ooms JF, Cornelis K, Wijeysundera HC, Vandeloo B, Van Der Heyden J, Kovac J, Wood D, Chan A, Wykyrzykowska J, Rosseel L, Cunnington M, van der Kley F, Rensing B, Voskuil M, Hildick-Smith D, Van Mieghem NM
Background: Transcatheter aortic valve implantation (TAVI) serves a growing range of patients with severe aortic stenosis (AS). TAVI has evolved to a streamlined procedure minimizing length of hospital stay. Aims: To evaluate the safety and efficacy of an early discharge (ED) strategy after TAVI. Methods: We performed an international, multi-center, prospective observational single-arm study in AS patients undergoing TAVI with the ACURATE valve platform. Eligibility for ED was assessed prior to...
Abstract
Annals of vascular surgery,
Volume 106, 13 2 2024, Pages 71-79
Toward Uniform Case Identification Criteria in Observational Studies on Peripheral Arterial Disease: A Scoping Review.
Keekstra N, Biemond M, van Schaik J, Schepers A, Hamming JF, van der Vorst JR, Lindeman JHN
Background: The diagnosis of peripheral arterial disease (PAD) is commonly applied for symptoms related to atherosclerotic obstructions in the lower extremity, though its clinical manifestations range from an abnormal ankle-brachial index to critical limb ischemia. Subsequently, management and prognosis of PAD vary widely with the disease stage. A critical aspect is how this variation is addressed in administrative database-based studies that rely on diagnosis codes for case identification. The...
Abstract
