8684 results
Cited 5 times since 2022 (1.5 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 16, Issue 4, 1 1 2022, Pages 319-326
Coronary volume to left ventricular mass ratio in patients with diabetes mellitus.
Kuneman JH, El Mahdiui M, van Rosendael AR, van den Hoogen IJ, Patel MR, Nørgaard BL, Fairbairn TA, Nieman K, Akasaka T, Berman DS, Hurwitz Koweek LM, Pontone G, Kawasaki T, Rønnow Sand NP, Jensen JM, Amano T, Poon M, Øvrehus KA, Sonck J, Rabbat MG, De Bruyne B, Rogers C, Matsuo H, Bax JJ, Leipsic JA, Knuuti J
Background: Diabetes mellitus is a major risk factor for coronary artery disease (CAD) and may provoke structural and functional changes in coronary vasculature. The coronary volume to left ventricular mass (V/M) ratio is a new anatomical parameter capable of revealing a potential physiological imbalance between coronary vasculature and myocardial mass. The aim of this study was to examine the V/M derived from coronary computed tomography angiography (CCTA) in patients with diabetes. Methods: Pa...
Abstract
Cited 5 times since 2022 (1.5 per year)
source: EuropePMC
Journal of tissue viability,
Volume 31, Issue 2, 1 1 2022, Pages 358-364
Translation and validation of the ELPO for Turkish population: Risk assessment scale for the development of pressure injuries due to surgical positioning.
Sengul T, Gul A, Yilmaz D, Gokduman T
Aim of the study: This study was conducted to translate the ELPO risk assessment scale for the development of pressure injuries due to surgical positioning to Turkish and to test its validity and reliability in the Turkish Population. Materials and methods: The data were collected using the patient identification form, the risk assessment scale for the prevention of injuries due to surgical positioning, and the Braden Scale. This scale consisted of a total of seven items, each of which contained...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Acta clinica Croatica,
Volume 60, Issue 3, 1 1 2022, Pages 361-366
SYNTHETIC CANNABINOID BONZAI RELATED CREATINE KINASE ENZYME ELEVATION: A TURKISH CENTER STUDY.
Erismis B, Yilmaz D, Polat O, Deniz H, Yucel MH, Hursitoglu M
Synthetic cannabinoid (locally named 'Bonzai' in Turkey) use is increasing worldwide (especially among people with low income). One of its harmful adverse effects is an increase in serum levels of muscle enzymes (i.e., creatine kinase [CK]). The aim of this study was to determine the prevalence of Bonzai use in patients admitted with elevated CK levels and to compare the 1-month survival status of Bonzai users with that of non-Bonzai users. This retrospective study was conducted on a t...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Pediatric emergency care,
Volume 38, Issue 2, 1 1 2022, Pages e871-e875
Evaluation of Pediatric Maxillofacial Injury: Who Is Critical?
Ulusoy E, Armağan C, Çağlar A, Er A, Akgül F, Çitlenbik H, Yilmaz D, Duman M
Objective: Isolated facial injuries are less common among pediatric trauma patients. The literature has focused on, especially, fractures in facial injuries. There is a limited number of studies evaluating all facial injuries in childhood. The study aims to evaluate the clinical characteristics of maxillofacial injuries and to identify patients who require further intervention. Methods: The data from pediatric patients with maxillofacial injury (
Abstract
Cited 27 times since 2022 (8.1 per year)
source: EuropePMC
JAMA cardiology,
Volume 7, Issue 2, 1 1 2022, Pages 175-183
Outcomes Associated With Catheter Ablation of Ventricular Tachycardia in Patients With Cardiac Sarcoidosis.
Siontis KC, Santangeli P, Muser D, Marchlinski FE, Zeppenfeld K, Hoogendoorn JC, Narasimhan C, Sauer WH, Zipse MM, Kapa S, Vedantham V, Rosenthal DG, Robinson MR, Patton KK, Murgatroyd F, Chicos AB, Soejima K, Roukoz H, Sacher F, Bhan A, Appelbaum J, Dickfeld T, Mankad P, Ellenbogen KA, Kron J, Kim HM, Froehlich J, Eagle KA, Bogun FM, Crawford TC
Importance: Ventricular tachycardia (VT) is associated with high mortality in patients with cardiac sarcoidosis (CS), and medical management of CS-associated VT is limited by high failure rates. The role of catheter ablation has been investigated in small, single-center studies. Objective: To investigate outcomes associated with VT ablation in patients with CS. Design, setting, and participants: This cohort study from the Cardiac Sarcoidosis Consortium registry (2003-2019) included 16 tertiary r...
Abstract
Cited 10 times since 2022 (3 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 24, Issue 2, 1 1 2022, Pages 296-305
Comparing clinical performance of current implantable cardioverter-defibrillator implantation recommendations in arrhythmogenic right ventricular cardiomyopathy.
Bosman LP, Bosman LP, Nielsen Gerlach CL, Cadrin-Tourigny J, Orgeron G, Tichnell C, Murray B, Bourfiss M, van der Heijden JF, Yap SC, Zeppenfeld K, van den Berg MP, Wilde AAM, Asselbergs FW, Tandri H, Calkins H, van Tintelen JP, James CA, Te Riele ASJM
Aims: Arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have an increased risk of ventricular arrhythmias (VA). Four implantable cardioverter-defibrillator (ICD) recommendation algorithms are available The International Task Force Consensus ('ITFC'), an ITFC modification by Orgeron et al. ('mITFC'), the AHA/HRS/ACC guideline for VA management ('AHA'), and the HRS expert consensus statement ('HRS'). This study aims to validate and compare the...
Abstract
Cited 25 times since 2022 (7.5 per year)
source: EuropePMC
Cancer treatment reviews,
Volume 104, 1 1 2022, Pages 102340
Treatment-driven tumour heterogeneity and drug resistance: Lessons from solid tumours.
Crucitta S, Cucchiara F, Mathijssen R, Mateo J, Jager A, Joosse A, Passaro A, Attili I, Petrini I, van Schaik R, Danesi R, Del Re M
Molecular heterogeneity characterizes tumours' evolution and adaptation and, because of its dynamics and continuous changes under external pressure, it is one of the major causes of drug resistance, contributing to therapy failure. Several studies reported evidence of molecular events occuring in individual tumours, including monoclonal or polyclonal resistance, and primary or secondary resistance mechanisms. While primary resistance is a phenomenon already present at the diagnosis of a tum...
Abstract
Cited 11 times since 2022 (3.3 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 8, Issue 4, 31 5 2022, Pages 437-449
Multielectrode Unipolar Voltage Mapping and Electrogram Morphology to Identify Post-Infarct Scar Geometry: Validation by Histology.
Glashan CA, Tofig BJ, Beukers H, Tao Q, Blom SA, Villadsen PR, Lassen TR, de Riva M, Kristiansen SB, Zeppenfeld K
Objectives: This study sought to evaluate the ability of uni- and bipolar electrograms collected with a multielectrode catheter with smaller electrodes to: 1) delineate scar; and 2) determine local scar complexity. Background: Early reperfusion results in variable endocardial scar, often overlaid with surviving viable myocardium. Although bipolar voltage (BV) mapping is considered the pillar of substrate-based ablation, the role of unipolar voltage (UV) mapping has not been sufficiently explored...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 9, 31 5 2022, Pages 793972
Hybrid CMR- and FDG-PET-Imaging Gives New Insights Into the Relationship of Myocardial Metabolic Activity and Fibrosis in Patients With Becker Muscular Dystrophy.
Vehof V, Büther F, Florian A, Drakos S, Chamling B, Kies P, Stegger L, Yilmaz A
Background: Cardiac involvement in patients with Becker muscular dystrophy (BMD) is an important predictor of mortality. The cardiac phenotype of BMD patients is characterized by slowly progressive myocardial fibrosis that starts in the left ventricular (LV) free wall segments and extends into the septal wall during the disease course. Purpose: Since the reason for this characteristic cardiac phenotype is unknown and comprehensive approaches using e.g. hybrid imaging combining cardiovascular mag...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Scientific reports,
Volume 12, Issue 1, 31 5 2022, Pages 1628
Chemotherapy response prediction with diffuser elapser network.
Koyuncu B, Melek A, Yilmaz D, Tuzer M, Unlu MB
In solid tumors, elevated fluid pressure and inadequate blood perfusion resulting from unbalanced angiogenesis are the prominent reasons for the ineffective drug delivery inside tumors. To normalize the heterogeneous and tortuous tumor vessel structure, antiangiogenic treatment is an effective approach. Additionally, the combined therapy of antiangiogenic agents and chemotherapy drugs has shown promising effects on enhanced drug delivery. However, the need to find the appropriate scheduling and...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Frontiers in genetics,
Volume 12, 31 5 2022, Pages 785947
Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair.
Schep R, Leemans C, Brinkman EK, van Schaik T, van Steensel B
DNA double-strand breaks (DSBs) can be repaired through various pathways. Understanding how these pathways are regulated is of great interest for cancer research and optimization of gene editing. The local chromatin environment can affect the balance between repair pathways, but this is still poorly understood. Here we provide a detailed protocol for DSB-TRIP, a technique that utilizes the specific DNA scars left by DSB repair pathways to study pathway usage throughout the genome. DSB-TRIP rando...
Abstract
Cited 7 times since 2022 (2.1 per year)
source: EuropePMC
BMC health services research,
Volume 22, Issue 1, 30 5 2022, Pages 129
Clarifying responsibility: professional digital health in the doctor-patient relationship, recommendations for physicians based on a multi-stakeholder dialogue in the Netherlands.
Silven AV, van Peet PG, Boers SN, Tabak M, de Groot A, Hendriks D, van Os HJA, Bonten TN, Atsma DE, de Graaf TJ, Sombroek MP, Chavannes NH, Villalobos-Quesada M
Background: Implementation of digital health (eHealth) generally involves adapting pre-established and carefully considered processes or routines, and still raises multiple ethical and legal dilemmas. This study aimed to identify challenges regarding responsibility and liability when prescribing digital health in clinical practice. This was part of an overarching project aiming to explore the most pressing ethical and legal obstacles regarding the implementation and adoption of digital health in...
Abstract
Cited 6 times since 2022 (1.8 per year)
source: EuropePMC
Journal of perinatal medicine,
Volume 50, Issue 4, 28 4 2022, Pages 467-475
Effects of music on sleep quality and comfort levels of pregnant women.
Sanlı Y, Goke Arslan G, Aypar Akbag NN, Canbulat Sahiner N, Yılmaz D, Yucel SC
Objectives: This pilot randomized controlled experimental study was conducted to investigate effects of music on sleep quality and comfort levels of pregnant women. Methods: The sample of the study consisted of 70 pregnant women who met the inclusion criteria and agreed to participate in the study. The pregnant women were assigned to the music (n=35) and control groups (n=35). In the study, the musical pieces composed in Uşşak mode were played for the participants in the music group. The pregnan...
Abstract
Cited 7 times since 2022 (2.1 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 15, Issue 2, 28 4 2022, Pages e009979
Nonsustained Ventricular Tachycardia Is Independently Associated With Sustained Ventricular Arrhythmias in Nonischemic Dilated Cardiomyopathy.
Piers SR, Androulakis AF, Yim KS, van Rein N, Venlet J, Kapel GF, Siebelink HM, Lamb HJ, Cannegieter SC, Man SC, Zeppenfeld K
Background: Spontaneous nonsustained ventricular tachycardia (NSVT) on Holter, VT inducibility during electrophysiology study, and late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) have been associated with sustained ventricular arrhythmias (SVAs) in nonischemic dilated cardiomyopathy (DCM). This study aimed to analyze whether these parameters carry independent prognostic value for spontaneous SVA in DCM. Methods: Between 2011 and 2018, patients with the DCM clinical spectrum...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
BMC ecology and evolution,
Volume 22, Issue 1, 28 4 2022, Pages 7
Long-term individualized monitoring of sympatric bat species reveals distinct species- and demographic differences in hibernation phenology.
Meier F, Grosche L, Reusch C, Runkel V, van Schaik J, Kerth G
Background: Hibernation allows species to conserve energy and thereby bridge unfavorable environmental conditions. At the same time, hibernation imposes substantial ecological and physiological costs. Understanding how hibernation timing differs within and between species can provide insights into the underlying drivers of this trade-off. However, this requires individualized long-term data that are often unavailable. Here, we used automatic monitoring techniques and a reproducible analysis pipe...
Abstract
Cited 3 times since 2022 (0.9 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 9, Issue 2, 27 4 2022, Pages 43
Sarcomere Disassembly and Transfection Efficiency in Proliferating Human iPSC-Derived Cardiomyocytes.
Yuan Q, Maas RGC, Brouwer ECJ, Pei J, Blok CS, Popovic MA, Paauw NJ, Bovenschen N, Hjortnaes J, Harakalova M, Doevendans PA, Sluijter JPG, van der Velden J, Buikema JW
Contractility of the adult heart relates to the architectural degree of sarcomeres in individual cardiomyocytes (CMs) and appears to be inversely correlated with the ability to regenerate. In this study we utilized multiple imaging techniques to follow the sequence of sarcomere disassembly during mitosis resulting in cellular or nuclear division in a source of proliferating human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). We observed that both mono- and binuclear hiPSC-CMs give ri...
Abstract
Cited 18 times since 2022 (5.4 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 35, Issue 7, 26 4 2022, Pages 703-711.e3
Noninvasive Left Ventricular Myocardial Work in Patients with Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction.
Meucci MC, Butcher SC, Galloo X, van der Velde ET, Marsan NA, Bax JJ, Delgado V
Background: Left ventricular (LV) global longitudinal strain (GLS) has been proposed as a sensitive marker of myocardial damage in patients with chronic severe aortic regurgitation (AR) and preserved LV ejection fraction (LVEF). However, LV GLS does not take into account the afterload. Noninvasive LV myocardial work is a novel parameter of LV myocardial performance, which integrates measurements of myocardial deformation and noninvasive blood pressure (afterload). The aims of this study were (1)...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Preventive veterinary medicine,
Volume 200, 25 4 2022, Pages 105582
Capacity of a Bayesian model to detect infected herds using disease dynamics and risk factor information from surveillance programmes: A simulation study.
Mercat M, van Roon AM, Santman-Berends I, van Schaik G, Nielen M, Graham D, More SJ, Guelbenzu-Gonzalo M, Fourichon C, Madouasse A
Control programmes against non-regulated infectious diseases of farm animals are widely implemented. Different control programmes have different definitions of "freedom from infection" which can lead to difficulties when trading animals between countries. When a disease is still present, in order to identify herds that are safe to trade with, estimating herd-level probabilities of being infected when classified "free from infection" using field data is of major interest. Our...
Abstract
Nederlands tijdschrift voor geneeskunde,
Volume 166, 24 4 2022, Pages D6172
[Genotype-guided antithrombotic therapy].
van den Broek WWA, Azzahhafi J, van Schaik RHN, Ten Berg JM
Although current literature indicates both a clinical and a cost-effective benefit of routine genotype-guided treatment of patients treated with clopidogrel, this strategy is not recommended in guidelines. In cardiology, but also in neurology and vascular surgery, the current scientific evidence for this is still insufficient. Nevertheless, the role of pharmacogenetics will gain importance in today's medical world, where the demand for personalised medicine is on the rise. The implementatio...
Abstract
Cited 13 times since 2022 (3.9 per year)
source: EuropePMC
eLife,
Volume 11, 24 4 2022, Pages e74387
Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses.
Catsburg LA, Westra M, van Schaik AM, MacGillavry HD
At postsynaptic sites of neurons, a prominent clathrin-coated structure, the endocytic zone (EZ), controls the trafficking of glutamate receptors and is essential for synaptic plasticity. Despite its importance, little is known about how this clathrin structure is organized to mediate endocytosis. We used live-cell and super-resolution microscopy to reveal the dynamic organization of this poorly understood clathrin structure in rat hippocampal neurons. We found that a subset of endocytic protein...
Abstract
