Research

Publications

Below you can find a list of our published research.

6131 results

Cited 29 times since 2010 (2 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 56, Issue 23, 1 1 2010, Pages 1922-1929 Timing of pre-operative Beta-blocker treatment in vascular surgery patients: influence on post-operative outcome. Flu WJ, van Kuijk JP, Chonchol M, Winkel TA, Verhagen HJ, Bax JJ, Poldermans D

Objectives: This study evaluated timing of β-blocker initiation before surgery and its relationship with: 1) pre-operative heart rate and high-sensitivity C-reactive-protein (hs-CRP) levels; and 2) post-operative outcome. Background: Perioperative guidelines recommend β-blocker initiation days to weeks before surgery, on the basis of expert opinions. Methods: In 940 vascular surgery patients, pre-operative heart rate and hs-CRP levels were recorded, next to timing of β-blocker initiation before... Abstract

Cited 16 times since 2010 (1.1 per year) source: EuropePMC

The American journal of medicine, Volume 123, Issue 11, 1 1 2010, Pages 978-986 Clinical relevance of hibernating myocardium in ischemic left ventricular dysfunction. Schinkel AF, Bax JJ, Delgado V, Poldermans D, Rahimtoola SH

Patients with chronic ischemic left ventricular dysfunction may have a substantial amount of viable, hibernating myocardium, which is a state of chronic contractile dysfunction with reduced blood flow at rest. Coronary revascularization in these patients may result in improvement of left ventricular function; in the absence of viability, left ventricular function will not improve postrevascularization. Various noninvasive imaging techniques are available for detection of viable myocardium, inclu... Abstract

Cited 40 times since 2010 (2.8 per year) source: EuropePMC

Respiratory medicine, Volume 104, Issue 11, 1 1 2010, Pages 1744-1749 Prevalence and potential determinants of exertional dyspnea after acute pulmonary embolism. Klok FA, van Kralingen KW, van Dijk AP, Heyning FH, Vliegen HW, Huisman MV

Background: The exact prevalence and etiology of exertional dyspnea in the clinical course of acute pulmonary embolism (PE) have not yet been established. Methods: A large cohort of consecutive patients diagnosed with acute PE was subjected to a dyspnea questionnaire and invited for cardiopulmonary work-up including the 6-min walk test, spirometry and echocardiography. The prevalence, severity, determinants and underlying diseases of exertional dyspnea were evaluated. Results: Of the registered... Abstract

Cited 19 times since 2010 (1.3 per year) source: EuropePMC

Pain medicine (Malden, Mass.), Volume 11, Issue 11, 1 1 2010, Pages 1628-1634 Pain symptoms accompanying chronic poststernotomy pain: a pilot study. van Leersum NJ, van Leersum RL, Verwey HF, Klautz RJ

Objective: Despite the technical developments in surgical procedures, chronic poststernotomy pain (CPSP) is still very common. Many theories for its cause have been proposed in the literature, but the etiology is still not clear. Pain along the sternal scar and in the upper extremities (sometimes accompanied with paresthesia) persists in about 30% of cases. These symptoms have been regarded as two separate complications. This study investigated all pain symptoms in patients following sternotomy.... Abstract

Cited 12 times since 2010 (0.8 per year) source: EuropePMC

The American journal of cardiology, Volume 106, Issue 10, 1 1 2010, Pages 1404-1409 Left ventricular muscle and fluid mechanics in acute myocardial infarction. Nucifora G, Delgado V, Bertini M, Marsan NA, Van de Veire NR, Ng AC, Siebelink HM, Schalij MJ, Holman ER, Sengupta PP, Bax JJ

Left ventricular (LV) diastolic filling is characterized by the formation of intraventricular rotational bodies of fluid (termed "vortex rings") that optimize the efficiency of LV ejection. The aim of the present study was to evaluate the morphology and dynamics of LV diastolic vortex ring formation early after acute myocardial infarction (AMI), in relation to LV diastolic function and infarct size. A total of 94 patients with a first ST-segment elevation AMI (59 ± 11 years; 78% men) w... Abstract

Cited 229 times since 2010 (16 per year) source: EuropePMC

JAMA, Volume 304, Issue 20, 1 1 2010, Pages 2245-2252 Mediastinoscopy vs endosonography for mediastinal nodal staging of lung cancer: a randomized trial. Annema JT, van Meerbeeck JP, Rintoul RC, Dooms C, Deschepper E, Dekkers OM, De Leyn P, Braun J, Carroll NR, Praet M, de Ryck F, Vansteenkiste J, Vermassen F, Versteegh MI, Veseliç M, Nicholson AG, Rabe KF, Tournoy KG

Context: Mediastinal nodal staging is recommended for patients with resectable non-small cell lung cancer (NSCLC). Surgical staging has limitations, which results in the performance of unnecessary thoracotomies. Current guidelines acknowledge minimally invasive endosonography followed by surgical staging (if no nodal metastases are found by endosonography) as an alternative to immediate surgical staging. Objective: To compare the 2 recommended lung cancer staging strategies. Design, setting, and... Abstract

Cited 18 times since 2010 (1.3 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 56, Issue 19, 1 1 2010, Pages 1567-1575 Effect of biventricular pacing on diastolic dyssynchrony. Shanks M, Bertini M, Delgado V, Ng AC, Nucifora G, van Bommel RJ, Borleffs CJ, Holman ER, van de Veire NR, Schalij MJ, Bax JJ

Objectives: This study sought to examine the changes in diastolic dyssynchrony with cardiac resynchronization therapy (CRT). Background: Little is known about the effect of CRT on diastolic dyssynchrony. Methods: Consecutive heart failure patients (n = 266, age 65.7 ± 10.0 years) underwent color-coded tissue Doppler imaging at baseline, 48 h, and 6 months after CRT. Systolic and diastolic dyssynchrony were defined as maximal time delay in peak systolic and early diastolic velocities, respectivel... Abstract

Cited 6 times since 2010 (0.4 per year) source: EuropePMC

Congenital heart disease, Volume 5, Issue 6, 1 1 2010, Pages 599-606 Congenital circumflex artery-coronary sinus fistula in an adult female associated with severe mitral regurgitation and myelodysplasy--case report and review of the literature. Said SA, van der Sluis A, Koster K, Sie H, Shahin GM

Background: Coronary artery fistulas are uncommon anomalies. They occur in 0.1-0.2% of patients undergoing coronary arteriography. The origin of the fistulas is the right coronary artery followed by the left anterior descending and lastly by the circumflex artery (17%). Termination into the right heart side occurs in 90% of cases. Termination into the coronary sinus is rare in 3% of cases. Circumflex artery-coronary sinus fistulas are even rarer. Design: A single case report and literature revie... Abstract

Cited 45 times since 2010 (3.1 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 90, Issue 5, 1 1 2010, Pages 1554-1561 More than 30 years' experience with surgical correction of atrioventricular septal defects. Hoohenkerk GJ, Bruggemans EF, Rijlaarsdam M, Schoof PH, Koolbergen DR, Hazekamp MG

Background: Outcome of surgical correction of atrioventricular septal defects (AVSD) still varies despite enhanced results. We reviewed our 30-year experience with AVSD repair and identified risk factors for mortality and reoperation. Methods: Between 1975 and 2006, 312 patients underwent surgery for complete AVSD (n = 209; 67.0%), partial AVSD (n = 76; 24.4%), or intermediate AVSD (n = 27; 8.6%). Mean age was 2.4 ± 3.9 years; 142 patients (45.5%) were younger than 6 months. Follow-up was 99.0%... Abstract

Cited 40 times since 2010 (2.8 per year) source: EuropePMC

Journal of magnetic resonance imaging : JMRI, Volume 32, Issue 5, 1 1 2010, Pages 1086-1094 Improved aortic pulse wave velocity assessment from multislice two-directional in-plane velocity-encoded magnetic resonance imaging. Westenberg JJ, de Roos A, Grotenhuis HB, Steendijk P, Hendriksen D, van den Boogaard PJ, van der Geest RJ, Bax JJ, Jukema JW, Reiber JH

Purpose: To evaluate the accuracy and reproducibility of aortic pulse wave velocity (PWV) assessment by in-plane velocity-encoded magnetic resonance imaging (MRI). Materials and methods: In 14 patients selected for cardiac catheterization on suspicion of coronary artery disease and 15 healthy volunteers, PWV was assessed with multislice two-directional in-plane velocity-encoded MRI (PWV(i.p.)) and compared with conventionally assessed PWV from multisite one-directional through-plane velocity-enc... Abstract

Cited 10 times since 2010 (0.7 per year) source: EuropePMC

American heart journal, Volume 160, Issue 5, 1 1 2010, Pages 870-876 Ventricular response to stress predicts outcome in adult patients with a systemic right ventricle. Winter MM, Scherptong RW, Kumar S, Bouma BJ, Tulevski II, Tops LF, Roest AA, Vliegen HW, de Roos A, Groenink M, Mulder BJ

Background: Previous studies demonstrated that ventricular response to stress cardiovascular magnetic resonance (CMR) is frequently abnormal in patients with a systemic right ventricle (RV). However, the clinical implications of these findings remained unknown. We sought to evaluate whether abnormal response to stress CMR predicts adverse outcome in patients with a systemic RV. Methods: Thirty-nine adult patients (54% male; mean age 26, range 18-65 years) with a systemic RV underwent stress CMR... Abstract

Cited 2 times since 2010 (0.1 per year) source: EuropePMC

Heart and vessels, Volume 26, Issue 3, 30 5 2010, Pages 235-241 The 5352 A allele of the pro-inflammatory caspase-1 gene predicts late-acquired stent malapposition in STEMI patients treated with sirolimus stents. Bergheanu SC, Pons D, van der Hoeven BL, Liem SS, Siegerink B, Schalij MJ, van der Bom JG, Jukema JW

Late-acquired stent malapposition (LASM) is a common finding after sirolimus-eluting stent (SES) implantation and may be the cause for late stent thrombosis. Inflammation may play a pivotal role in LASM just as it plays in stent restenosis. We have therefore investigated seven polymorphisms involved in inflammatory processes, related in previous reports to restenosis, on the risk of LASM in SES patients. Patients with ST-elevation myocardial infarction who underwent SES implantation and had intr... Abstract

Cited 31 times since 2010 (2.2 per year) source: EuropePMC

European heart journal, Volume 32, Issue 5, 29 5 2010, Pages 637-645 Diagnostic performance of non-invasive multidetector computed tomography coronary angiography to detect coronary artery disease using different endpoints: detection of significant stenosis vs. detection of atherosclerosis. van Velzen JE, Schuijf JD, de Graaf FR, Boersma E, Pundziute G, Spanó F, Boogers MJ, Schalij MJ, Kroft LJ, de Roos A, Jukema JW, van der Wall EE, Bax JJ

Aims: The positive predictive value of multidetector computed tomography angiography (CTA) for detecting significant stenosis remains limited. Possibly CTA may be more accurate in the evaluation of atherosclerosis rather than in the evaluation of stenosis severity. However, a comprehensive assessment of the diagnostic performance of CTA in comparison with both conventional coronary angiography (CCA) and intravascular ultrasound (IVUS) is lacking. Therefore, the aim of the study was to systematic... Abstract

Cited 28 times since 2010 (1.9 per year) source: EuropePMC

The American journal of cardiology, Volume 106, Issue 12, 26 4 2010, Pages 1747-1753 Usefulness of hypertriglyceridemic waist phenotype in type 2 diabetes mellitus to predict the presence of coronary artery disease as assessed by computed tomographic coronary angiography. de Graaf FR, Schuijf JD, Scholte AJ, Djaberi R, van Velzen JE, Roos CJ, Kroft LJ, de Roos A, van der Wall EE, Wouter Jukema J, Després JP, Bax JJ

The present study tested whether in patients with type 2 diabetes mellitus (DM) the combination of increased waist circumference and increased plasma triglyceride (TG) levels can predict the presence of coronary artery disease (CAD) as assessed by multidetector computed tomographic coronary angiography (CTA). In 202 patients with type 2 DM who were clinically referred for CTA, waist circumference and TG levels were measured. Patients were divided into 4 groups according to waist circumference me... Abstract

Cited 56 times since 2010 (3.9 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 12, Issue 12, 25 4 2010, Pages 1673-1690 Management of patients receiving implantable cardiac defibrillator shocks: recommendations for acute and long-term patient management. Braunschweig F, Boriani G, Bauer A, Hatala R, Herrmann-Lingen C, Kautzner J, Pedersen SS, Pehrson S, Ricci R, Schalij MJ

Abstract

Cited 71 times since 2010 (4.9 per year) source: Scopus

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 39, Issue 6, 22 4 2010, Pages 1054-1056 First-in-man implantation of a trans-catheter aortic valve in a mitral annuloplasty ring: novel treatment modality for failed mitral valve repair. de Weger A, Ewe SH, Delgado V, Bax JJ

The trans-catheter valve-in-valve concept has become a feasible therapeutic option for patients with failing degenerated bioprosthesis, who are deemed inoperable. However, little is known about the feasibility of this technique in failed valve annuloplasty. We report the first-in-man implantation of a trans-catheter aortic valve within a mitral annuloplasty ring. Through a trans-apical trans-catheter approach, a 26-mm Sapien-Edwards valve was successfully implanted in a 72-year-old man with isch... Abstract

Cited 6 times since 2010 (0.4 per year) source: EuropePMC

Journal of vascular surgery, Volume 53, Issue 2, 20 3 2010, Pages 399-406 The influence of polyvascular disease on the obesity paradox in vascular surgery patients. van Kuijk JP, Flu WJ, Galal W, Chonchol M, Goei D, Verhagen HJ, Bax JJ, Poldermans D

Background: Obesity is a risk factor for atherosclerosis, a polyvascular process associated with reduced survival. In nonvascular surgery populations, a paradox between body mass index (BMI) and survival is described. This paradox includes reduced survival in underweight patients, whereas overweight and obese patients have a survival benefit. No clear explanation for this paradox has been given. Therefore, we evaluated the presence of the obesity paradox in vascular surgery patients and the infl... Abstract

Cited 6 times since 2010 (0.4 per year) source: EuropePMC

British journal of haematology, Volume 152, Issue 4, 19 3 2010, Pages 493-496 Rapid identification of IDH1 and IDH2 mutations in acute myeloid leukaemia using high resolution melting curve analysis. Noordermeer SM, Tönnissen E, Vissers I, van der Heijden A, van de Locht LT, Deutz-Terlouw PP, Marijt EW, Jansen JH, van der Reijden BA

Abstract

Cited 36 times since 2010 (2.5 per year) source: EuropePMC

PloS one, Volume 5, Issue 10, 19 3 2010, Pages e13482 The population genetics of Pseudomonas aeruginosa isolates from different patient populations exhibits high-level host specificity. van Mansfeld R, Jongerden I, Bootsma M, Buiting A, Bonten M, Willems R

Objective: To determine whether highly prevalent P. aeruginosa sequence types (ST) in Dutch cystic fibrosis (CF) patients are specifically linked to CF patients we investigated the population structure of P. aeruginosa from different clinical backgrounds. We first selected the optimal genotyping method by comparing pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST) and multilocus variable number tandem-repeat analysis (MLVA). Methods: Selected P. aeruginosa isolates (n =... Abstract

Cited 66 times since 2010 (4.6 per year) source: EuropePMC

European journal of nuclear medicine and molecular imaging, Volume 38, Issue 2, 17 3 2010, Pages 230-238 Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion SPECT. Boogers MJ, Chen J, van Bommel RJ, Borleffs CJ, Dibbets-Schneider P, van der Hiel B, Al Younis I, Schalij MJ, van der Wall EE, Garcia EV, Bax JJ

Purpose: The aim of the current study was to evaluate the relationship between the site of latest mechanical activation as assessed with gated myocardial perfusion SPECT (GMPS), left ventricular (LV) lead position and response to cardiac resynchronization therapy (CRT). Methods: The patient population consisted of consecutive patients with advanced heart failure in whom CRT was currently indicated. Before implantation, 2-D echocardiography and GMPS were performed. The echocardiography was perfor... Abstract