6161 results
JACC. Case reports,
Volume 3, Issue 2, 17 3 2021, Pages 217-219
Björk-Fontan and the Restoration of Right-Sided Conduits.
de Winter RJ, Koolbergen DR
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Sensors (Basel, Switzerland),
Volume 21, Issue 4, 15 3 2021, Pages 1361
Early Detection of Fluid Retention in Patients with Advanced Heart Failure: A Review of a Novel Multisensory Algorithm, HeartLogic<sup>TM</sup>.
Feijen M, Egorova AD, Beeres SLMA, Treskes RW
Heart failure (HF) hospitalisations due to decompensation are associated with shorter life expectancy and lower quality of life. These hospitalisations pose a significant burden on the patients, doctors and healthcare resources. Early detection of an upcoming episode of decompensation may facilitate timely optimisation of the ambulatory medical treatment and thereby prevent heart-failure-related hospitalisations. The HeartLogicTM algorithm combines data from five sensors of cardiac implantable e...
Abstract
Cited 18 times since 2021 (4.3 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 12 2 2021, Pages 631985
Myocardial Disease and Long-Distance Space Travel: Solving the Radiation Problem.
Meerman M, Bracco Gartner TCL, Buikema JW, Wu SM, Siddiqi S, Bouten CVC, Grande-Allen KJ, Suyker WJL, Hjortnaes J
Radiation-induced cardiovascular disease is a well-known complication of radiation exposure. Over the last few years, planning for deep space missions has increased interest in the effects of space radiation on the cardiovascular system, as an increasing number of astronauts will be exposed to space radiation for longer periods of time. Research has shown that exposure to different types of particles found in space radiation can lead to the development of diverse cardiovascular disease via fibro...
Abstract
Cited 6 times since 2021 (1.4 per year)
source: EuropePMC
BMJ open,
Volume 11, Issue 2, 12 2 2021, Pages e041553
Prehospital triage of patients with acute cardiac complaints: study protocol of HART-c, a multicentre prospective study.
de Koning E, Biersteker TE, Beeres S, Bosch J, Backus BE, Kirchhof CJ, Alizadeh Dehnavi R, Silvius HA, Schalij M, Boogers MJ
Introduction: Emergency department (ED) overcrowding is a major healthcare problem associated with worse patient outcomes and increased costs. Attempts to reduce ED overcrowding of patients with cardiac complaints have so far focused on in-hospital triage and rapid risk stratification of patients with chest pain at the ED. The Hollands-Midden Acute Regional Triage-Cardiology (HART-c) study aimed to assess the amount of patients left at home in usual ambulance care as compared with the new prehos...
Abstract
Cited 9 times since 2021 (2.2 per year)
source: EuropePMC
Journal of magnetic resonance imaging : JMRI,
Volume 54, Issue 2, 10 2 2021, Pages 411-420
Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy.
Bakermans AJ, Boekholdt SM, de Vries DK, Reckman YJ, Farag ES, de Heer P, Uthman L, Denis SW, Zuurbier CJ, Houtkooper RH, Koolbergen DR, Kluin J, Planken RN, Lamb HJ, Webb AG, Strijkers GJ, Beard DA, Jeneson JAL, Nederveen AJ
Background: Proton magnetic resonance spectroscopy (1 H-MRS) of the human heart is deemed to be a quantitative method to investigate myocardial metabolite content, but thorough validations of in vivo measurements against invasive techniques are lacking. Purpose: To determine measurement precision and accuracy for quantifications of myocardial total creatine and triglyceride content with localized 1 H-MRS. Study type: Test-retest repeatability and measurement validation study. Subjects: Sixteen v...
Abstract
Cited 27 times since 2021 (6.5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 6, 10 2 2021, Pages 1085-1095
Prognostic Implications of a Novel Algorithm to Grade Secondary Tricuspid Regurgitation.
Fortuni F, Dietz MF, Prihadi EA, van der Bijl P, De Ferrari GM, Knuuti J, Bax JJ, Delgado V, Marsan NA
Objectives: A novel tricuspid regurgitation (TR) grading system, using vena contracta (VC) width and effective regurgitant orifice area (EROA), was proposed and validated based on its prognostic usefulness. Background: The clinical need of a new grading system for TR has recently been emphasized to depict the whole spectrum of TR severity, particularly beyond severe TR (massive or torrential). Methods: TR severity was characterized in 1,129 patients with moderate or severe secondary TR (STR). Re...
Abstract
Cited 7 times since 2021 (1.7 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 9 2 2021, Pages 638487
Multi-Modality Imaging for Interventions in Tricuspid Valve Disease.
Fortuni F, Hirasawa K, Bax JJ, Delgado V, Ajmone Marsan N
Several studies have demonstrated that severe tricuspid regurgitation (TR) has a significant negative impact on morbidity and mortality. Nowadays, several therapeutic options to treat TR are available and patients at high surgical risk can also be treated with transcatheter procedures. For the management of patients with TR, an accurate assessment of the tricuspid valve and its surrounding structures is therefore of crucial importance and has gained significant interest in the medical community....
Abstract
Cited 27 times since 2021 (6.5 per year)
source: EuropePMC
STAR protocols,
Volume 2, Issue 1, 9 2 2021, Pages 100334
Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes.
Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, Wu JC, Sluijter JPG, Wu SM, Buikema JW
Since the discovery of human induced pluripotent stem cells (hiPSCs), numerous strategies have been established to efficiently derive cardiomyocytes from hiPSCs (hiPSC-CMs). Here, we describe a cost-effective strategy for the subsequent massive expansion (>250-fold) of high-purity hiPSC-CMs relying on two aspects: removal of cell-cell contacts and small-molecule inhibition with CHIR99021. The protocol maintains CM functionality, allows cryopreservation, and the cells can be used in downstream...
Abstract
Cited 1 times since 2021 (0.2 per year)
source: EuropePMC
Der Urologe. Ausg. A,
Volume 60, Issue 3, 9 2 2021, Pages 318-330
[Urological care in practices and clinics during the corona virus pandemic in Germany].
Kriegmair MC, Speck T, Schneider AW, Volkmer B, Michel MS
The coronavirus pandemic has had an immediate and far-reaching effect on the care of urological patients. The pandemic monitor of the German Society for Urology was able to record the restrictions on patient care in urological practices and clinics by means of regular surveys of the members. A total of 689 responses at four survey time points were included. In April there was a reduction in urological inpatients to 44% and the number of patients in practices dropped to 50%. Available operating t...
Abstract
Journal of clinical medicine,
Volume 10, Issue 4, 8 2 2021, Pages 649
Mitral Valve Annulus Dimensions Assessment with Three-Dimensional Echocardiography Versus Computed Tomography: Implications for Transcatheter Interventions.
Hirasawa K, Vo NM, Gegenava T, Pio SM, van Wijngaarden SE, Ajmone Marsan N, Bax JJ, Delgado V
The aim of this study is to evaluate the agreement between three-dimensional (3D) transesophageal echocardiography (TEE) and multidetector computed tomography (MDCT) for assessing mitral annular (MA) dimensions. A total of 105 patients (79 ± 9 years old, 52% male) who underwent clinically indicated 3D TEE and MDCT feasible for MA geometrical assessment were included. Using dedicated semi-automated postprocessing software, MA geometry, including mitral annular area (MAA), perimeter, septal-latera...
Abstract
Cited 4 times since 2021 (1 per year)
source: EuropePMC
Nature communications,
Volume 12, Issue 1, 8 2 2021, Pages 995
Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A,
Abstract
Cited 14 times since 2021 (3.4 per year)
source: EuropePMC
Angiogenesis,
Volume 24, Issue 3, 7 1 2021, Pages 567-581
Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization.
Baganha F, de Jong RCM, Peters EA, Voorham W, Jukema JW, Delibegovic M, de Vries MR, Quax PHA
Objective: Statins pleiotropically provide additional benefits in reducing atherosclerosis, but their effects on intraplaque angiogenesis (IPA) and hemorrhage (IPH) remain unclear. Therefore, we discriminated statin's lipid-lowering dependent and independent effects on IPA and IPH. Approach and results: ApoE3*Leiden mice are statin-responsive due to ApoE and LDLR presence, but also allow to titrate plasma cholesterol levels by diet. Therefore, ApoE3*Leiden mice were fed a high-cholesterol-i...
Abstract
Cited 21 times since 2021 (5 per year)
source: EuropePMC
International journal of cardiology,
Volume 331, 3 1 2021, Pages 316-321
Standard and emerging CMR methods for mitral regurgitation quantification.
Fidock B, Archer G, Barker N, Elhawaz A, Al-Mohammad A, Rothman A, Hose R, Hall IR, Grech E, Briffa N, Lewis N, van der Geest RJ, Zhang JM, Zhong L, Swift AJ, Wild JM, De Gárate E, Bucciarelli-Ducci C, Bax JJ, Plein S, Myerson S, Garg P
Background: There are several methods to quantify mitral regurgitation (MR) by cardiovascular magnetic resonance (CMR). The interoperability of these methods and their reproducibility remains undetermined. Objective: To determine the agreement and reproducibility of different MR quantification methods by CMR across all aetiologies. Methods: Thirty-five patients with MR were recruited (primary MR = 12, secondary MR = 10 and MVR = 13). Patients underwent CMR, including cines and four-dimensional f...
Abstract
Cited 8 times since 2021 (1.9 per year)
source: EuropePMC
Journal of internal medicine,
Volume 290, Issue 1, 2 1 2021, Pages 141-156
Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases.
de Vries MR, Ewing MM, de Jong RCM, MacArthur MR, Karper JC, Peters EAB, Nordzell M, Karabina SAP, Sexton D, Dahlbom I, Bergman A, Mitchell JR, Frostegård J, Kuiper J, Ninio E, Jukema JW, Pettersson K, Quax PHA
Background: Phosphorylcholine (PC) is an important pro-inflammatory damage-associated molecular pattern. Previous data have shown that natural IgM anti-PC protects against cardiovascular disease. We aimed to develop a monoclonal PC IgG antibody with anti-inflammatory and anti-atherosclerotic properties. Methods: Using various techniques PC antibodies were validated and optimized. In vivo testing was performed in a femoral artery cuff model in ApoE3*Leiden mice. Safety studies are performed in ra...
Abstract
Cited 15 times since 2021 (3.6 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 77, Issue 6, 1 1 2021, Pages 761-771
Preventing Arrhythmic Death in Patients With Tetralogy of Fallot: JACC Review Topic of the Week.
Cohen MI, Khairy P, Zeppenfeld K, Van Hare GF, Lakkireddy DR, Triedman JK
Patients with tetralogy of Fallot are at risk for ventricular arrhythmias and sudden cardiac death. These abnormalities are associated with pulmonary regurgitation, right ventricular enlargement, and a substrate of discrete, slowly-conducting isthmuses. Although these arrhythmic events are rare, their prediction is challenging. This review will address contemporary risk assessment and prevention strategies. Numerous variables have been proposed to predict who would benefit from an implantable ca...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Pediatric cardiology,
Volume 42, Issue 4, 1 1 2021, Pages 866-874
Oxygen Uptake Efficiency Slope is Strongly Correlated to VO<sub>2peak</sub> Long-Term After Arterial Switch Operation.
Terol Espinosa de Los Monteros C, Van der Palen RLF, Hazekamp MG, Rammeloo L, Jongbloed MRM, Blom NA, Harkel ADJT
After the arterial switch operation (ASO) for transposition of the great arteries (TGA), many patients have an impaired exercise tolerance. Exercise tolerance is determined with cardiopulmonary exercise testing by peak oxygen uptake (VO2peak). Unlike VO2peak, the oxygen uptake efficiency slope (OUES) does not require a maximal effort for interpretation. The value of OUES has not been assessed in a large group of patients after ASO. The purpose of this study was to determine OUES and VO2peak, eva...
Abstract
Cited 7 times since 2021 (1.7 per year)
source: EuropePMC
Tissue engineering. Part C, Methods,
Volume 27, Issue 2, 1 1 2021, Pages 100-114
Advanced <i>In Vitro</i> Modeling to Study the Paradox of Mechanically Induced Cardiac Fibrosis.
Bracco Gartner TCL, Stein JM, Muylaert DEP, Bouten CVC, Doevendans PA, Khademhosseini A, Suyker WJL, Sluijter JPG, Hjortnaes J
In heart failure, cardiac fibrosis is the result of an adverse remodeling process. Collagen is continuously synthesized in the myocardium in an ongoing attempt of the heart to repair itself. The resulting collagen depositions act counterproductively, causing diastolic dysfunction and disturbing electrical conduction. Efforts to treat cardiac fibrosis specifically have not been successful and the molecular etiology is only partially understood. The differentiation of quiescent cardiac fibroblasts...
Abstract
Cited 819 times since 2021 (195.8 per year)
source: EuropePMC
European heart journal,
Volume 42, Issue 6, 1 1 2021, Pages 563-645
2020 ESC Guidelines for the management of adult congenital heart disease.
Baumgartner H, De Backer J, Babu-Narayan SV, Budts W, Chessa M, Diller GP, Lung B, Kluin J, Lang IM, Meijboom F, Moons P, Mulder BJM, Oechslin E, Roos-Hesselink JW, Schwerzmann M, Sondergaard L, Zeppenfeld K, ESC Scientific Document Group
Abstract
Pediatric emergency care,
Volume 37, Issue 2, 1 1 2021, Pages e77-e78
Unexpected Diagnosis in an Adolescent With Bruises and Ecchymosis: Celiac Disease.
Er A, Çağlar A, Kuyum P, Akgül F, Ulusoy E, Çitlenbik H, Aksoy BY, Yilmaz D, Arslan N, Duman M
Abstract: Acquired coagulopathy is a rare but challenging diagnosis for pediatric emergency physicians. Although the coagulopathy usually presents with mild skin and mucosal hemorrhages, it also can lead to life-threatening events. Thus, accurate interpretation of hints obtained from a detailed history, physical examination, and laboratory findings is essential for the prompt diagnosis and management. This case demonstrates an uncommon cause of coagulopathy; celiac disease that presented with sp...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Journal of thoracic disease,
Volume 13, Issue 2, 1 1 2021, Pages 592-599
Quality assessment of robot assisted thoracic surgical resection of non-small cell lung cancer: nodal upstaging and mediastinal recurrence.
Shahin GM, Topal B, Pouwels S, Markou TL, Boon R, Stigt JA
Background: Robot assisted thoracic surgery (RATS) is the minimally invasive surgical technique of choice for treatment of patients with non-small cell lung cancer (NSCLC), at the Isala Hospital. The aim of this study is to compare clinical and pathological staging results and mediastinal recurrence after RATS for anatomical resections of lung cancer as surrogate markers for quality of mediastinal lymph node dissection (MLND). Methods: This single institute retrospective study was conducted in p...
Abstract
