6161 results
Cited 67 times since 2021 (15.8 per year)
source: EuropePMC
Biomedicines,
Volume 9, Issue 1, 9 2 2021, Pages 57
Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence?
Kurakula K, Smolders VFED, Tura-Ceide O, Jukema JW, Quax PHA, Goumans MJ
Pulmonary arterial hypertension (PAH) is a rare, complex, and progressive disease that is characterized by the abnormal remodeling of the pulmonary arteries that leads to right ventricular failure and death. Although our understanding of the causes for abnormal vascular remodeling in PAH is limited, accumulating evidence indicates that endothelial cell (EC) dysfunction is one of the first triggers initiating this process. EC dysfunction leads to the activation of several cellular signalling path...
Abstract
Cited 4 times since 2021 (0.9 per year)
source: EuropePMC
European radiology,
Volume 31, Issue 7, 6 1 2021, Pages 5068-5076
Associations between left ventricular function, vascular function and measures of cerebral small vessel disease: a cross-sectional magnetic resonance imaging study of the UK Biobank.
van Hout MJP, Dekkers IA, Westenberg JJM, Schalij MJ, Scholte AJHA, Lamb HJ
Objectives: Impaired cardiovascular function has been associated with cognitive deterioration; however, to what extent cardiovascular dysfunction plays a role in structural cerebral changes remains unclear. We studied whether vascular and left ventricular (LV) functions are associated with measures of cerebral small vessel disease (cSVD) in the middle-aged general population. Methods: In this cross-sectional analysis of the UK Biobank, 4366 participants (54% female, mean age 61 years) underwent...
Abstract
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 34, Issue 4, 6 1 2021, Pages 451-452
Left Ventricular Myocardial Work Indices: A Potential Step Forward for the Assessment of Myocardial Performance in Severe Aortic Stenosis: Reply to "Is It Fair to Use the Current Estimation of Myocardial Work in Patients with Significant Aortic Stenosis?"
Fortuni F, Bax JJ, Delgado V, Ajmone Marsan N
Abstract
Cited 4 times since 2021 (0.9 per year)
source: EuropePMC
Health expectations : an international journal of public participation in health care and health policy,
Volume 24, Issue 2, 6 1 2021, Pages 456-467
Patient and public involvement cultures and the perceived impact in the vulnerable context of palliative care: A qualitative study.
Melchior I, van der Heijden A, Stoffers E, Suntjens F, Moser A
Background: Cultural values are crucial to the practice and impact of patient and public involvement (PPI) in research. Objective: To understand different PPI cultures among research teams and the impacts of PPI associated with each culture type. Design: A participatory action research design. Setting and participants: The setting was 10 palliative care research projects. Seventeen patients and members of the public and 31 researchers participated. Intervention: A programme consisting of four co...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 14, Issue 1, 5 1 2021, Pages e011107
Computed Tomography-Derived Transesophageal Echocardiographic Views: Step Forward for Procedural Planning of Transcatheter Tricuspid Valve Annuloplasty.
Fortuni F, Hirasawa K, Marques AI, Pio SM, Chimed S, Lustosa R, Tjahjadi C, Wang X, Bax JJ, Ajmone Marsan N, Delgado V
Abstract
Cited 93 times since 2021 (21.9 per year)
source: EuropePMC
Nature communications,
Volume 12, Issue 1, 5 1 2021, Pages 24
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A,
Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, the genetic component underlying this phenomenon is not established. We assess sex-dimorphic (73,089/50,404 women and 67,506/47,806 men) and sex-combined (151,188/105,056 individuals) fasting glucose/fasting insulin genetic effects via genome-wide association stu...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 143, 4 1 2021, Pages 60-66
Influence of Chronic Obstructive Pulmonary Disease on Atrial Mechanics by Speckle Tracking Echocardiography in Patients With Atrial Fibrillation.
Goedemans L, Leung M, van der Bijl P, Abou R, Vo NM, Ajmone Marsan N, Delgado V, Bax JJ
The present study aimed to examine differences in left- and right atrial characteristics between atrial fibrillation (AF) patients with and without chronic obstructive pulmonary disease (COPD). For this, 420 patients (mean age 68 ± 10 years, 73% female) with first diagnosis of AF and baseline echocardiography were included. Of these, 143 COPD patients were compared with 277 patients without COPD matched by age, gender and body surface area. Additionally 38 healthy controls without cardiovascular...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Journal of periodontology,
Volume 92, Issue 9, 3 1 2021, Pages 1295-1305
Salivary and serum concentrations of monocyte chemoattractant protein-1, macrophage inhibitory factor, and fractalkine in relation to rheumatoid arthritis and periodontitis.
Yilmaz D, Gönüllü E, Gürsoy M, Könönen E, Gürsoy UK
Background: Monocyte chemoattractant protein-1 (MCP-1), macrophage migration inhibitory factor (MIF), and fractalkine are chemokines that are expressed by a variety of cell types to regulate macrophage inflammatory response. The aim of the study was to examine the effects of periodontitis and rheumatoid arthritis (RA) on their serum and salivary concentrations. Methods: Adults with either periodontitis (P, n = 21), or with rheumatoid arthritis (RA, n = 23), or with both diseases (RA+P, n = 23) w...
Abstract
Cited 4 times since 2021 (0.9 per year)
source: EuropePMC
BJS open,
Volume 5, Issue 1, 1 1 2021, Pages zraa041
Systematic approach towards reliable estimation of abdominal aortic aneurysm size by ultrasound imaging and CT.
Tomee SM, Meijer CA, Kies DA, le Cessie S, Wasser MNJM, Golledge J, Hamming JF, Lindeman JHN
Background: The management of abdominal aortic aneurysm (AAA) is fully dictated by AAA size, but there are no uniform measurement guidelines, and systematic differences exist between ultrasound- and CT-based size estimation. The aim of this study was to devise a uniform ultrasound acquisition and measurement protocol, and to test whether harmonization of ultrasound and CT readings is feasible. Methods: A literature review was undertaken to evaluate evidence for ultrasound-based measurement of AA...
Abstract
Cited 18 times since 2021 (4.2 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 15, Issue 4, 1 1 2021, Pages 322-330
Progression of whole-heart Atherosclerosis by coronary CT and major adverse cardiovascular events.
van Rosendael AR, Lin FY, van den Hoogen IJ, Ma X, Gianni U, Al Hussein Alawamlh O, Al'Aref SJ, Peña JM, Andreini D, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Conte E, Marques H, de Araújo Gonçalves P, Gottlieb I, Hadamitzky M, Leipsic J, Maffei E, Pontone G, Raff GL, Shin S, Kim YJ, Lee BK, Chun EJ, Sung JM, Lee SE, Han D, Berman DS, Virmani R, Samady H, Stone P, Narula J, Bax JJ, Shaw LJ, Min JK, Chang HJ
Background: The current study aimed to examine the independent prognostic value of whole-heart atherosclerosis progression by serial coronary computed tomography angiography (CCTA) for major adverse cardiovascular events (MACE). Methods: The multi-center PARADIGM study includes patients undergoing serial CCTA for symptomatic reasons, ≥2 years apart. Whole-heart atherosclerosis was characterized on a segmental level, with co-registration of baseline and follow-up CCTA, and summed to per-patient l...
Abstract
European heart journal. Cardiovascular Imaging,
Volume 22, Issue 2, 1 1 2021, Pages 186-187
Predicting left ventricular functional recovery after transcatheter aortic valve implantation with computed tomography-derived extracellular volume.
van der Bijl P, Delgado V, Bax JJ
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
JRSM cardiovascular disease,
Volume 10, 1 1 2021, Pages 20480040211006582
Risk assessment in aortic aneurysm repair by medical specialists versus the American College of Surgeons National Surgical Quality Improvement Program risk calculator outcomes.
van Schaik J, Hers TM, van Rijswijk CS, Schooneveldt MS, Putter H, Eefting D, van der Vorst JR
Objective: The aim of this online clinical vignette-based survey study was to compare risk assessments by vascular surgeons, anaesthesiologists and interventional radiologists involved in treating patients with aortic aneurysms in the Netherlands with the NSQIP risk calculator outcomes. Methods: Participants, recruited using purposive sampling, provided their estimation of the likelihood of postoperative complications and events following aortic surgery in five fictional cases. These cases were...
Abstract
Cited 1 times since 2021 (0.2 per year)
source: EuropePMC
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies,
Volume 22, Issue 1, 1 1 2021, Pages e79-e90
Rhinovirus Detection in the Nasopharynx of Children Undergoing Cardiac Surgery Is Not Associated With Longer PICU Length of Stay: Results of the Impact of Rhinovirus Infection After Cardiac Surgery in Kids (RISK) Study.
Roeleveld PP, Van Rijn AL, de Wilde RBP, van Zwet EW, Wink J, Rozendaal L, Hogenbirk K, Hazekamp MG, Man WH, Sidorov I, Kraakman MEM, Claas ECJ, de Jonge E, Kroes ACM, de Vries JJC
Objectives: To determine whether children with asymptomatic carriage of rhinovirus in the nasopharynx before elective cardiac surgery have an increased risk of prolonged PICU length of stay. Study design: Prospective, single-center, blinded observational cohort study. Setting: PICU in a tertiary hospital in The Netherlands. Patients: Children under 12 years old undergoing elective cardiac surgery were enrolled in the study after informed consent of the parents/guardians. Interventions: The paren...
Abstract
Cited 6 times since 2021 (1.4 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 32, Issue 1, 1 1 2021, Pages 122-129
The significance of symptoms before and after surgery for anomalous aortic origin of coronary arteries in adolescents and adults.
Meijer FMM, Egorova AD, Jongbloed MRM, Koppel C, Habib G, Hazekamp MG, Vliegen HW, Kies P
Objectives: The aim of this study is to describe the significance of symptoms preoperatively and at medium-term follow-up in adolescent and adult patients who underwent surgery of anomalous aortic origin of a coronary artery (AAOCA). Methods: Consecutive patients who underwent surgery for AAOCA in our tertiary referral centre between 2001 and 2018 were included. Clinical characteristics and symptoms were evaluated and medium-term outcomes were recorded. Symptoms were classified according to the...
Abstract
Cited 36 times since 2021 (8.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 22, Issue 2, 1 1 2021, Pages 142-152
Right ventricular myocardial work: proof-of-concept for non-invasive assessment of right ventricular function.
Butcher SC, Fortuni F, Montero-Cabezas JM, Abou R, El Mahdiui M, van der Bijl P, van der Velde ET, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Right ventricular myocardial work (RVMW) is a novel method for non-invasive assessment of right ventricular (RV) function utilizing RV pressure-strain loops. This study aimed to explore the relationship between RVMW and invasive indices of right heart catheterization (RHC) in a cohort of patients with heart failure with reduced left ventricular ejection fraction (HFrEF), and to compare values of RVMW with those of a group of patients without cardiovascular disease. Methods and results: Non...
Abstract
Cited 33 times since 2021 (7.8 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 22, Issue 2, 1 1 2021, Pages 168-176
Pressure-volume loop validation of TAPSE/PASP for right ventricular arterial coupling in heart failure with pulmonary hypertension.
Schmeisser A, Rauwolf T, Groscheck T, Kropf S, Luani B, Tanev I, Hansen M, Meißler S, Steendijk P, Braun-Dullaeus RC
Aims: The aim of this study was to validate the tricuspid annular plane systolic excursion/systolic pulmonary artery (PA) pressure (TAPSE/PASP) ratio with the invasive pressure-volume (PV) loop-derived end-systolic right ventricular (RV) elastance/PA elastance (Ees/Ea) ratio in patients with heart failure with reduced ejection fraction (HFREF) and secondary pulmonary hypertension (PH). Methods and results: The relationship of TAPSE and TAPSE/PASP with RV-PV loop (single-beat)-derived contractili...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Haematologica,
Volume 106, Issue 1, 1 1 2021, Pages 259-263
Macrophage-HFE controls iron metabolism and immune responses in aged mice.
Tangudu NK, Yilmaz D, Wörle K, Gruber A, Colucci S, Leopold K, Muckenthaler MU, Vujic Spasic M
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Bratislavske lekarske listy,
Volume 122, Issue 5, 1 1 2021, Pages 357-361
The relationship between neutrophil/lymphocyte ratio and uric acid levels in multiple sclerosis patients.
Bolayir A, Cigdem B, Gokce SF, Yilmaz D
Background: In this study, we aimed to determine whether neutrophil / lymphocyte ratio (NLR), obtained by dividing the number of neutrophils by the number of lymphocytes, and uric acid (UA) levels in multiple sclerosis (MS) patients vary compared with healthy controls and to establish correlations among these changes themselves as well as between such changes and MS subtypes, immunomodulatory drug use, the duration of the disease and prognosis. Methods: 150 patients who presented to our hospital...
Abstract
Cited 27 times since 2021 (6.3 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 23, Issue 1, 1 1 2021, Pages 147-148
Recommendations for participation in leisure-time physical activity and competitive sports of patients with arrhythmias and potentially arrhythmogenic conditions. Part 2: ventricular arrhythmias, channelopathies, and implantable defibrillators.
Heidbuchel H, Arbelo E, D'Ascenzi F, Borjesson M, Boveda S, Castelletti S, Miljoen H, Mont L, Niebauer J, Papadakis M, Pelliccia A, Saenen J, Sanz de la Garza M, Schwartz PJ, Sharma S, Zeppenfeld K, Corrado D, EAPC/EHRA update of the Recommendations for participation in leisure-time physical activity and competitive sports in patients with arrhythmias and potentially arrhythmogenic conditions
This paper belongs to a series of recommendation documents for participation in leisure-time physical activity and competitive sports by the European Association of Preventive Cardiology (EAPC). Together with an accompanying paper on supraventricular arrhythmias, this second text deals specifically with those participants in whom some form of ventricular rhythm disorder is documented, who are diagnosed with an inherited arrhythmogenic condition, and/or who have an implanted pacemaker or cardiove...
Abstract
Cited 23 times since 2021 (5.4 per year)
source: EuropePMC
Emerging infectious diseases,
Volume 27, Issue 1, 1 1 2021, Pages 289-293
Detection of Norovirus Variant GII.4 Hong Kong in Asia and Europe, 2017-2019.
Chan MC, Roy S, Bonifacio J, Zhang LY, Chhabra P, Chan JCM, Celma C, Igoy MA, Lau SL, Mohammad KN, Vinjé J, Vennema H, Breuer J, Koopmans M, de Graaf M, for NOROPATROL2
We report a new norovirus GII.4 variant, GII.4 Hong Kong, with low-level circulation in 4 Eurasia countries since mid-2017. Amino acid substitutions in key residues on the virus capsid associated with the emergence of pandemic noroviruses suggest that GII.4 Hong Kong has the potential to become the next pandemic variant.
Abstract
