6161 results
Cited 4 times since 2020 (0.9 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 45, 1 1 2020, Pages 4318-4320
The difficult decision of when and in whom to perform isolated tricuspid valve surgery.
Delgado V, Ajmone Marsan N, Bax JJ
Abstract
Cited 2 times since 2020 (0.5 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 6, Issue 14, 1 1 2020, Pages 1794-1796
Automated Functional Substrate Mapping: Further Hurdles to Be Cleared.
Zeppenfeld K, Porta-Sánchez A
Abstract
Huisarts en wetenschap,
Volume 63, Issue 12, 30 5 2020, Pages 27-32
E-health bij poliklinische follow-up van myocardinfarctpatiënten.
Treskes R, van Winden L, van Keulen N, van der Velde E, Beeres S, Atsma D, Schalij MJ
Abstract
Cited 2 times since 2020 (0.5 per year)
source: EuropePMC
Current cardiology reports,
Volume 23, Issue 1, 27 4 2020, Pages 4
Cardiac Sympathetic Innervation Imaging with PET Radiotracers.
van der Bijl P, Knuuti J, Delgado V, Bax JJ
Purpose of review: The present article reviews the pathophysiology of cardiac sympathetic denervation, the principles of positron emission tomography (PET) imaging of the sympathetic innervation of the heart and its potential clinical role, based on current and expected future evidence. Recent findings: Imaging of cardiac sympathetic denervation can be performed with radiolabeled noradrenaline analogues, e.g., 11C-hydroxyephedrine. A greater burden of sympathetic denervation carries prognostic s...
Abstract
Cited 5 times since 2020 (1.1 per year)
source: Scopus
Animals : an open access journal from MDPI,
Volume 10, Issue 12, 26 4 2020, Pages E2214
Social Context Influences Resting Physiology in Dogs.
Kortekaas K, Kotrschal K
Domestication has affected the social life of dogs. They seem to be less dependent on their pack members than wolves, potentially causing dogs to be more alert towards their environment, especially when resting. Such a response has been found in dogs resting alone compared to wolves in the same situation. However, as this may be influenced by social context, we compared alertness (i.e., degree of activation along the sleep-wake continuum-measured via cardiac parameters) of pack-living and enclos...
Abstract
Cited 47 times since 2020 (10.8 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 4, 25 4 2020, Pages 854-866
Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations.
Reid A, Ben Zekry S, Turaga M, Tarazi S, Bax JJ, Wang DD, Piazza N, Bapat VN, Ihdayhid AR, Cavalcante JL, Blanke P, Leipsic J
With the advent of transcatheter mitral valve replacement (TMVR), the concept of the neo-left ventricular outflow tract (LVOT) was introduced and remains an essential component of treatment planning. This paper describes the LVOT anatomy and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT while discussing the current evidence and outstanding challenges. It also discusses the technical and hemodynamic factors that play a major role in assessing the neo-...
Abstract
Cited 4 times since 2020 (0.9 per year)
source: Scopus
Frontiers in psychology,
Volume 11, 24 4 2020, Pages 568199
Context-Specific Arousal During Resting in Wolves and Dogs: Effects of Domestication?
Jean-Joseph H, Kortekaas K, Range F, Kotrschal K
Due to domestication, dogs differ from wolves in the way they respond to their environment, including to humans. Selection for tameness and the associated changes to the autonomic nervous system (ANS) regulation have been proposed as the primary mechanisms of domestication. To test this idea, we compared two low-arousal states in equally raised and kept wolves and dogs: resting, a state close to being asleep, and inactive wakefulness, which together take up an important part in the time budgets...
Abstract
Cited 97 times since 2020 (22.2 per year)
source: EuropePMC
Nature genetics,
Volume 52, Issue 12, 23 4 2020, Pages 1314-1332
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E,
Genetic studies of blood pressure (BP) to date have mainly analyzed common variants (minor allele frequency > 0.05). In a meta-analysis of up to ~1.3 million participants, we discovered 106 new BP-associated genomic regions and 87 rare (minor allele frequency ≤ 0.01) variant BP associations (P
Abstract
Cited 24 times since 2020 (5.5 per year)
source: EuropePMC
ESC heart failure,
Volume 8, Issue 1, 23 4 2020, Pages 566-576
Meta-analysis of echocardiographic quantification of left ventricular filling pressure.
Jones R, Varian F, Alabed S, Morris P, Rothman A, Swift AJ, Lewis N, Kyriacou A, Wild JM, Al-Mohammad A, Zhong L, Dastidar A, Storey RF, Swoboda PP, Bax JJ, Garg P
Aims: The clinical reliability of echocardiographic surrogate markers of left ventricular filling pressures (LVFPs) across different cardiovascular pathologies remains unanswered. The main objective was to evaluate the evidence of how effectively different echocardiographic indices estimate true LVFP. Methods and results: Design: this is a systematic review and meta-analysis. Data source: Scopus, PubMed and Embase. Eligibility criteria for selecting studies were those that used echocardiography...
Abstract
Cited 26 times since 2020 (5.9 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 112, Issue 4, 19 3 2020, Pages 1150-1159
Multiinstitutional Phase 2 Clinical Trial of Intraoperative Molecular Imaging of Lung Cancer.
Gangadharan S, Sarkaria IN, Rice D, Murthy S, Braun J, Kucharczuk J, Predina J, Singhal S
Background: Intraoperative molecular imaging (IMI) may improve surgical outcomes during pulmonary resection for lung cancer. A multiinstitutional phase 2 IMI clinical trial was conducted using a near-infrared, folate receptor-targeted contrast agent for lung adenocarcinomas, OTL38. The primary goal was to determine whether OTL38 improved surgeons' ability to identify difficult to find nodules, occult cancers, and positive margins. Methods: Patients with lung nodules received OTL38 (0.025 mg...
Abstract
Cited 47 times since 2020 (10.7 per year)
source: EuropePMC
Frontiers in nutrition,
Volume 7, 19 3 2020, Pages 597600
The Impact of Obesity and Lifestyle on the Immune System and Susceptibility to Infections Such as COVID-19.
de Frel DL, Atsma DE, Pijl H, Seidell JC, Leenen PJM, Dik WA, van Rossum EFC
Background: COVID-19 is a global challenge to healthcare. Obesity is common in patients with COVID-19 and seems to aggravate disease prognosis. In this review we explore the link between obesity, chronic disease, lifestyle factors and the immune system, and propose societal interventions to enhance global immunity. Search Strategy and Selection Criteria: We performed three literature searches using the keywords (1) coronavirus AND comorbidities, (2) comorbidities AND immune system, and (3) lifes...
Abstract
Cited 38 times since 2020 (8.7 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 1, 18 3 2020, Pages 233-242
The Relationship Between Coronary Calcification and the Natural History of Coronary Artery Disease.
Jin HY, Weir-McCall JR, Leipsic JA, Son JW, Sellers SL, Shao M, Blanke P, Ahmadi A, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, de Araujo Goncalves P, Shin S, Choi JH, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Chinnaiyan K, Raff G, Al-Mallah MH, Lin FY, Min JK, Sung JM, Lee SE, Chang HJ
Objectives: The aim of the current study was to explore the impact of plaque calcification in terms of absolute calcified plaque volume (CPV) and in the context of its percentage of the total plaque volume at a lesion and patient level on the progression of coronary artery disease. Background: Coronary artery calcification is an established marker of risk of future cardiovascular events. Despite this, plaque calcification is also considered a marker of plaque stability, and it increases in respo...
Abstract
Cited 17 times since 2020 (3.9 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 9, Issue 23, 16 3 2020, Pages e017094
Extreme Diversity of the Human Vascular Mesenchymal Cell Landscape.
Bruijn LE, van den Akker BEWM, van Rhijn CM, Hamming JF, Lindeman JHN
Background Human mesenchymal cells are culprit factors in vascular (patho)physiology and are hallmarked by phenotypic and functional heterogeneity. At present, they are subdivided by classic umbrella terms, such as "fibroblasts," "myofibroblasts," "smooth muscle cells," "fibrocytes," "mesangial cells," and "pericytes." However, a discriminative marker-based subclassification has to date not been established. Methods and Results As a fir...
Abstract
Cited 142 times since 2020 (32.4 per year)
source: EuropePMC
Nature reviews. Cardiology,
Volume 18, Issue 4, 13 2 2020, Pages 291-304
Diabesity: the combined burden of obesity and diabetes on heart disease and the role of imaging.
Ng ACT, Delgado V, Borlaug BA, Bax JJ
Diabesity is a term used to describe the combined adverse health effects of obesity and diabetes mellitus. The worldwide dual epidemic of obesity and type 2 diabetes is an important public health issue. Projections estimate a sixfold increase in the number of adults with obesity in 40 years and an increase in the number of individuals with diabetes to 642 million by 2040. Increased adiposity is the strongest risk factor for developing diabetes. Early detection of the effects of diabesity on the...
Abstract
Cited 3 times since 2020 (0.7 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 44, Issue 1, 12 2 2020, Pages 120-128
Mechanical extraction of cardiac implantable electronic devices leads with long dwell time: Efficacy and safety of the step up approach.
Lensvelt LMH, Egorova AD, Schalij MJ, Yilmaz D, Kennergren C, Bootsma M, van Erven L
The aim of this study was to evaluate the efficacy and safety of the stepwise mechanical transvenous lead extraction approach in a patient population with chronically implanted transvenous leads with a long dwell time. From January 2014 till December 2018, all lead extractions with lead dwell time ≥5 years performed at our tertiary centre were retrospectively analysed. A total of 173 leads, from 78 patients (median age 68 years; 81% male) with a median dwell time of 9 years (interquartile range...
Abstract
Trends in cardiovascular medicine,
Volume 31, Issue 8, 11 2 2020, Pages 495-496
Editorial commentary: Future of transcatheter mitral valve interventions for secondary mitral regurgitation.
Vo NM, Bax JJ, Delgado V
Abstract
Cited 8 times since 2020 (1.8 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 48, Issue 5, 11 2 2020, Pages 1434-1444
Global and segmental absolute stress myocardial blood flow in prediction of cardiac events: [<sup>15</sup>O] water positron emission tomography study.
Harjulahti E, Maaniitty T, Nammas W, Stenström I, Biancari F, Bax JJ, Knuuti J, Saraste A
Purpose: We evaluated the value of reduced global and segmental absolute stress myocardial blood flow (sMBF) quantified by [15O] water positron emission tomography (PET) for predicting cardiac events in patients with suspected obstructive coronary artery disease (CAD). Methods: Global and segmental sMBF during adenosine stress were retrospectively quantified in 530 symptomatic patients who underwent [15O] water PET for evaluation of coronary stenosis detected by coronary computed tomography angi...
Abstract
Cited 24 times since 2020 (5.5 per year)
source: EuropePMC
Cell reports. Medicine,
Volume 1, Issue 9, 10 2 2020, Pages 100146
Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons.
Rother N, Yanginlar C, Lindeboom RGH, Bekkering S, van Leent MMT, Buijsers B, Jonkman I, de Graaf M, Baltissen M, Lamers LA, Riksen NP, Fayad ZA, Mulder WJM, Hilbrands LB, Joosten LAB, Netea MG, Vermeulen M, van der Vlag J, Duivenvoorden R
Hydroxychloroquine is being investigated for a potential prophylactic effect in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but its mechanism of action is poorly understood. Circulating leukocytes from the blood of coronavirus disease 2019 (COVID-19) patients show increased responses to Toll-like receptor ligands, suggestive of trained immunity. By analyzing interferon responses of peripheral blood mononuclear cells from healthy donors conditioned with heat-killed Can...
Abstract
Cited 20 times since 2020 (4.5 per year)
source: Scopus
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 34, Issue 3, 9 2 2020, Pages 257-266
Left Ventricular Myocardial Work in Patients with Severe Aortic Stenosis.
Fortuni F, Butcher SC, van der Kley F, Lustosa RP, Karalis I, de Weger A, Priori SG, van der Bijl P, Bax JJ, Delgado V, Ajmone Marsan N
Background: Left ventricular myocardial work (LVMW) is a novel method to assess left ventricular (LV) function using pressure-strain loops that takes into consideration LV afterload. The estimation of LV afterload in patients with severe aortic stenosis (AS) may be challenging, and no study so far has investigated LVMW in this setting. The aim of this study was to develop a method to calculate LVMW in patients with severe AS and to analyze its relationship with heart failure symptoms. Methods: I...
Abstract
Cited 91 times since 2020 (20.7 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 15, Issue 2, 9 2 2020, Pages 93-109
Society of Cardiovascular Computed Tomography / North American Society of Cardiovascular Imaging - Expert Consensus Document on Coronary CT Imaging of Atherosclerotic Plaque.
Shaw LJ, Blankstein R, Bax JJ, Ferencik M, Bittencourt MS, Min JK, Berman DS, Leipsic J, Villines TC, Dey D, Al'Aref S, Williams MC, Lin F, Baskaran L, Litt H, Litmanovich D, Cury R, Gianni U, van den Hoogen I, R van Rosendael A, Budoff M, Chang HJ, E Hecht H, Feuchtner G, Ahmadi A, Ghoshajra BB, Newby D, Chandrashekhar YS, Narula J
Coronary computed tomographic angiography (CCTA) provides a wealth of clinically meaningful information beyond anatomic stenosis alone, including the presence or absence of nonobstructive atherosclerosis and high-risk plaque features as precursors for incident coronary events. There is, however, no uniform agreement on how to identify and quantify these features or their use in evidence-based clinical decision-making. This statement from the Society of Cardiovascular Computed Tomography and Nort...
Abstract
