9618 results
International journal of epidemiology,
Volume 49, Issue 1, 1 1 2020, Pages 357
Corrigendum to: Cohort Profile: The Hoorn Studies.
Rutters F, Nijpels G, Elders P, Stehouwer CDA, van der Heijden AA, Groeneveld L, 't Hart LM, Dekker JM, Beulens JWJ
Abstract
Cited 50 times since 2020 (9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 75, Issue 7, 1 1 2020, Pages 750-758
Prognostic Value of Left Ventricular Global Longitudinal Strain in Patients With Secondary Mitral Regurgitation.
Namazi F, van der Bijl P, Hirasawa K, Kamperidis V, van Wijngaarden SE, Mertens B, Leon MB, Hahn RT, Stone GW, Narula J, Ajmone Marsan N, Delgado V, Bax JJ
Background: Left ventricular (LV) systolic function may be overestimated in patients with secondary mitral regurgitation (MR) when using LV ejection fraction (EF). LV global longitudinal strain (GLS) is a less load-dependent measure of LV function. However, the prognostic value of LV GLS in secondary MR has not been evaluated. Objectives: This study sought to demonstrate the prognostic value of LV GLS over LVEF in patients with secondary MR. Methods: A total of 650 patients (mean 66 ± 11 years o...
Abstract
Cited 19 times since 2020 (3.4 per year)
source: EuropePMC
Journal of religion and health,
Volume 59, Issue 1, 1 1 2020, Pages 29-39
Determination of Compassion Levels of Nurses Working at a University Hospital.
Arkan B, Yılmaz D, Düzgün F
This study was conducted to determine the compassion levels of nurses working in a university hospital. The study sample consists of 227 nurses who were available and participated in the research voluntarily during the study. The study data were collected by using "Nurse Description Form" and "Compassion Scale (CS)." In the analysis of the study data, number, percentage, mean and independent T test and ANOVA test were used. The total mean score of CS of the nurses was found a...
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 75, Issue 4, 1 1 2020, Pages 448-451
Sustained Low-Density Lipoprotein Cholesterol Lowering With Alirocumab in ODYSSEY OUTCOMES.
Goodman SG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Harrington RA, Jukema JW, White HD, Zeiher AM, Schwartz GG, ODYSSEY OUTCOMES Investigators†
Abstract
Cited 10 times since 2020 (1.8 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 57, Issue 2, 1 1 2020, Pages 293-299
Risk factors and clinical significance of elevated mitral valve gradient following valve repair for degenerative disease.
Tomšič A, Hiemstra YL, Arabkhani B, Mertens BJA, van Brakel TJ, Versteegh MIM, Marsan NA, Klautz RJM, Palmen M
Objectives: The risk factors and clinical effect of elevated mitral valve (MV) gradients after valve repair for degenerative valve disease remain insufficiently understood. Methods: Between January 2004 and December 2015, a total of 484 patients underwent valve repair for degenerative disease. A true-sized full annuloplasty ring was implanted in all cases. We analysed the effect of preoperative and intraoperative factors on the postrepair gradient. Additionally, we explored the effect of postrep...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 28, Issue 2, 1 1 2020, Pages 110-111
A 55-year-old man with mild shortness of breath.
Egorova AD, Smit JM, Kiès P
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 28, Issue 2, 1 1 2020, Pages 104-107
A 55-year-old man with mild shortness of breath.
Egorova AD, Smit JM, Kiès P
Abstract
Cited 6 times since 2020 (1.1 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 6, 1 1 2020, Pages 739-747
The year in cardiology: imaging.
Pennell D, Delgado V, Knuuti J, Maurovich-Horvat P, Bax JJ
Abstract
Cited 27 times since 2020 (4.9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 2, 1 1 2020, Pages 119-123
EACVI survey on standardization of cardiac chambers quantification by transthoracic echocardiography.
Ajmone Marsan N, Michalski B, Cameli M, Podlesnikar T, Manka R, Sitges M, Dweck MR, Haugaa KH
Aims: To evaluate standard reporting of cardiac chambers size and function by transthoracic echocardiography (TTE), the EACVI Scientific Initiatives Committee performed a survey across European centres. In particular, the routine use of three-dimensional echocardiography (3DE) and speckle tracking-derived myocardial deformation imaging (STE) was explored. Methods and results: A total of 96 European Echocardiography Laboratories from 22 different countries responded to the survey, which consisted...
Abstract
Cited 7 times since 2020 (1.3 per year)
source: EuropePMC
Cells,
Volume 9, Issue 2, 1 1 2020, Pages E336
Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice.
Parma L, Peters HAB, Baganha F, Sluimer JC, de Vries MR, Quax PHA
Unstable atherosclerotic plaques frequently show plaque angiogenesis which increases the chance of rupture and thrombus formation leading to infarctions. Hypoxia plays a role in angiogenesis and inflammation, two processes involved in the pathogenesis of atherosclerosis. We aim to study the effect of resolution of hypoxia using carbogen gas (95% O2, 5% CO2) on the remodeling of vein graft accelerated atherosclerotic lesions in ApoE3*Leiden mice which harbor plaque angiogenesis. Single treatment...
Abstract
Cited 22 times since 2020 (4 per year)
source: EuropePMC
Cardiovascular research,
Volume 116, Issue 2, 1 1 2020, Pages 416-428
Short-term preoperative protein restriction attenuates vein graft disease via induction of cystathionine γ-lyase.
Trocha KM, Kip P, Tao M, MacArthur MR, Treviño-Villarreal JH, Longchamp A, Toussaint W, Lambrecht BN, de Vries MR, Quax PHA, Mitchell JR, Ozaki CK
Aims: Therapies to prevent vein graft disease, a major problem in cardiovascular and lower extremity bypass surgeries, are currently lacking. Short-term preoperative protein restriction holds promise as an effective preconditioning method against surgical stress in rodent models, but whether it can improve vein graft patency after bypass surgery is undetermined. Here, we hypothesized that short-term protein restriction would limit vein graft disease via up-regulation of cystathionine γ-lyase and...
Abstract
Cited 32 times since 2020 (5.8 per year)
source: EuropePMC
Nucleic acids research,
Volume 48, Issue 4, 1 1 2020, Pages 2156-2172
Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins.
Qin L, Bdira FB, Sterckx YGJ, Volkov AN, Vreede J, Giachin G, van Schaik P, Ubbink M, Dame RT
H-NS proteins act as osmotic sensors translating changes in osmolarity into altered DNA binding properties, thus, regulating enterobacterial genome organization and genes transcription. The molecular mechanism underlying the switching process and its conservation among H-NS family members remains elusive. Here, we focus on the H-NS family protein MvaT from Pseudomonas aeruginosa and demonstrate experimentally that its protomer exists in two different conformations, corresponding to two different...
Abstract
Cited 14 times since 2020 (2.5 per year)
source: EuropePMC
Academic medicine : journal of the Association of American Medical Colleges,
Volume 95, Issue 2, 1 1 2020, Pages 293-300
"A Friendly Place to Grow as an Educator": A Qualitative Study of Community and Relationships Among Medical Student Coaches.
Sheu L, Hauer KE, Schreiner K, van Schaik SM, Chang A, O'Brien BC
Purpose: The rise of coaching programs in medical education sparks questions about ways to support physician coaches in learning new educational practices specific to coaching. How coaches learn from one another is of particular interest considering the potential value of social learning. Using communities of practice as a conceptual framework, the authors examine the sense of community and relationships among coaches in a new medical student coaching program, the value of this community, and th...
Abstract
Cited 15 times since 2020 (2.7 per year)
source: EuropePMC
Pharmacogenomics,
Volume 21, Issue 3, 1 1 2020, Pages 181-193
<i>OPRM1</i> and <i>COMT</i> polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery.
Matic M, Matic M, de Hoogd S, de Wildt SN, Tibboel D, Knibbe CA, van Schaik RH
Aim: Investigate the potential role of OPRM1 (mu-opioid receptor) and COMT (catechol-O-methyltransferase enzyme) polymorphisms in postoperative acute, chronic and experimental thermal pain. Methods: A secondary analysis of 125 adult cardiac surgery patients that were randomized between fentanyl and remifentanil during surgery and genotyped. Results: Patients in the fentanyl group with the COMT high-pain sensitivity haplotype required less postoperative morphine compared with the average-pain sen...
Abstract
Cited 12 times since 2020 (2.2 per year)
source: EuropePMC
The Journal of antimicrobial chemotherapy,
Volume 75, Issue 2, 1 1 2020, Pages 283-291
Tandem amplification of the vanM gene cluster drives vancomycin resistance in vancomycin-variable enterococci.
Sun L, Chen Y, Hua X, Chen Y, Hong J, Wu X, Jiang Y, van Schaik W, Qu T, Yu Y
Background: Vancomycin-variable enterococci (VVE) are a potential risk factor for vancomycin resistance gene dissemination and clinical treatment failure. vanM has emerged as a new prevalent resistance determinant among clinical enterococci in China. A total of 54 vancomycin-susceptible enterococci (VSE) isolates carrying incomplete vanM gene clusters were isolated in our previous study. Objectives: To determine the potential of vanM-carrying VSE to develop vancomycin resistance and investigate...
Abstract
Cited 173 times since 2020 (31.2 per year)
source: EuropePMC
Current opinion in microbiology,
Volume 53, 1 1 2020, Pages 35-43
Horizontal transfer of antibiotic resistance genes in the human gut microbiome.
McInnes RS, McCallum GE, Lamberte LE, van Schaik W
Infections caused by antibiotic-resistant bacteria are a major threat to public health. The pathogens causing these infections can acquire antibiotic resistance genes in a process termed horizontal gene transfer (HGT). HGT is a common event in the human gut microbiome, that is, the microbial ecosystem of the human intestinal tract. HGT in the gut microbiome can occur via different mechanisms of which transduction and conjugation have been best characterised. Novel bioinformatic tools and experim...
Abstract
Cited 28 times since 2020 (5 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 14, Issue 5, 30 5 2020, Pages 400-406
Percent atheroma volume: Optimal variable to report whole-heart atherosclerotic plaque burden with coronary CTA, the PARADIGM study.
van Rosendael AR, Lin FY, Ma X, van den Hoogen IJ, Gianni U, Al Hussein O, Al'Aref SJ, Peña JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Conte E, Marques H, de Araújo Gonçalves P, Gottlieb I, Hadamitzky M, Leipsic JA, Maffei E, Pontone G, Raff GL, Shin S, Kim YJ, Lee BK, Chun EJ, Sung JM, Lee SE, Berman DS, Virmani R, Samady H, Stone PH, Narula J, Bax JJ, Shaw LJ, Min JK, Chang HJ
Background and aims: Different methodologies to report whole-heart atherosclerotic plaque on coronary computed tomography angiography (CCTA) have been utilized. We examined which of the three commonly used plaque burden definitions was least affected by differences in body surface area (BSA) and sex. Methods: The PARADIGM study includes symptomatic patients with suspected coronary atherosclerosis who underwent serial CCTA >2 years apart. Coronary lumen, vessel, and plaque were quantified from...
Abstract
Cited 4 times since 2020 (0.7 per year)
source: EuropePMC
Journal of applied physiology (Bethesda, Md. : 1985),
Volume 128, Issue 3, 30 5 2020, Pages 545-553
The proarrhythmic features of pathological cardiac hypertrophy in neonatal rat ventricular cardiomyocyte cultures.
Neshati Z, Schalij MJ, de Vries AAF
Different factors may trigger arrhythmias in diseased hearts, including fibrosis, cardiomyocyte hypertrophy, hypoxia, and inflammation. This makes it difficult to establish the relative contribution of each of them to the occurrence of arrhythmias. Accordingly, in this study, we used an in vitro model of pathological cardiac hypertrophy (PCH) to investigate its proarrhythmic features and the underlying mechanisms independent of fibrosis or other PCH-related processes. Neonatal rat ventricular ca...
Abstract
Cited 8 times since 2020 (1.4 per year)
source: EuropePMC
Trials,
Volume 21, Issue 1, 28 4 2020, Pages 112
Pelvic floor rehabilitation to improve functional outcome and quality of life after surgery for rectal cancer: study protocol for a randomized controlled trial (FORCE trial).
Kalkdijk-Dijkstra AJ, van der Heijden JAG, van Westreenen HL, Broens PMA, Trzpis M, Pierie JPEN, Klarenbeek BR, FORCE Trial Group
Background: After low anterior resection (LAR), up to 90% of patients develop anorectal dysfunction. Especially fecal incontinence has a major impact on the physical, psychological, social, and emotional functioning of the patient but also on the Dutch National Healthcare budget with more than €2000 spent per patient per year. No standardized treatment is available to help these patients. Common treatment nowadays is focused on symptom relief, consisting of lifestyle advices and pharmacotherapy...
Abstract
Cited 22 times since 2020 (4 per year)
source: EuropePMC
Orphanet journal of rare diseases,
Volume 15, Issue 1, 28 4 2020, Pages 28
Depressive symptoms in Fabry disease: the importance of coping, subjective health perception and pain.
Körver S, Geurtsen GJ, Hollak CEM, van Schaik IN, Longo MGF, Lima MR, Vedolin L, Dijkgraaf MGW, Langeveld M
Background: Despite the high prevalence of depressive symptoms in Fabry disease (FD), it is unclear which patient characteristics are important in relation to these symptoms. Additionally, the impact of coping styles in relation to depressive symptoms in FD has been unexplored. Determining the impact of different factors relating to depressive symptoms in FD can guide both prevention and treatment of these symptoms. Methods: Depressive symptoms (Center for Epidemiologic Studies Depression scale...
Abstract
