Research

Publications

Below you can find a list of our published research.

6221 results

Cited 26 times since 2004 (1.2 per year) source: EuropePMC

The American journal of cardiology, Volume 94, Issue 1, 1 1 2004, Pages 130-132 Effect of left ventricular remodeling after cardiac resynchronization therapy on frequency of ventricular arrhythmias. Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Zeppenfeld K, Bootsma M, St John Sutton M, van Erven L, van der Wall EE, Schalij MJ

We evaluated whether cardiac resynchronization therapy affects the prevalence of ventricular tachycardia in relation to reverse remodeling in patients with end-stage heart failure. Clinical, echocardiographic, and implantable cardioverter-defibrillator (ICD) data of 17 patients with ICDs were obtained before and after they had received an upgrade to an ICD-cardiac resynchronization therapy device. Abstract

Cited 23 times since 2004 (1.1 per year) source: EuropePMC

The American journal of medicine, Volume 117, Issue 1, 1 1 2004, Pages 1-9 Long-term prognostic value of dobutamine stress echocardiography compared with myocardial perfusion scanning in patients unable to perform exercise tests. Schinkel AF, Bax JJ, Elhendy A, van Domburg RT, Valkema R, Vourvouri E, Bountioukos M, Rizzello V, Biagini E, Agricola E, Krenning EP, Simoons ML, Poldermans D

Purpose: To compare the long-term prognostic value of dobutamine stress echocardiography and dobutamine stress single photon emission computed tomography (SPECT) in patients unable to perform an exercise test. Methods: We assessed the prognostic value of dobutamine stress technetium 99m ((99m)Tc)-sestamibi SPECT and dobutamine stress echocardiography in 301 patients who were unable to perform exercise tests. Outcomes during a mean (+/- SD) follow-up of 7.3 +/- 2.8 years were overall death, cardi... Abstract

Cited 13 times since 2004 (0.6 per year) source: EuropePMC

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 17, Issue 7, 1 1 2004, Pages 739-743 Prognostic value of dobutamine stress echocardiography in patients with normal left ventricular systolic function. Elhendy A, Schinkel AF, Bax JJ, Van Domburg RT, Poldermans D

Background: Patients with normal left ventricular systolic function are considered to be at a relatively low risk for cardiac events. There are scarce data regarding association of ischemia on stress imaging techniques with outcome in these patients. Objectives: We sought to assess the prognostic significance of dobutamine-induced myocardial ischemia for patients with normal left ventricular systolic function. Methods: We studied 528 patients with normal baseline left ventricular systolic functi... Abstract

Cited 253 times since 2004 (12.1 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 44, Issue 1, 1 1 2004, Pages 1-9 Echocardiographic evaluation of cardiac resynchronization therapy: ready for routine clinical use? A critical appraisal. Bax JJ, Ansalone G, Breithardt OA, Derumeaux G, Leclercq C, Schalij MJ, Sogaard P, St John Sutton M, Nihoyannopoulos P

Cardiac resynchronization therapy (CRT) has been proposed as an alternative treatment in patients with severe, drug-refractory heart failure. The clinical results are promising, and improvement in symptoms, exercise capacity, and systolic left ventricular (LV) function have been demonstrated after CRT, accompanied by a reduction in hospitalization and a superior survival as compared with optimized medical therapy alone. However, 20% to 30% of patients do not respond to CRT. Currently, patients a... Abstract

Cited 12 times since 2004 (0.6 per year) source: EuropePMC

Pediatric hematology and oncology, Volume 21, Issue 5, 1 1 2004, Pages 403-410 Safety profiles of Fe2+ and Fe3+ oral preparations in the treatment of iron deficiency anemia in children. Kavakli K, Yilmaz D, Cetinkaya B, Balkan C, Sözmen EY, Sağin FG

The major purpose of this study was to compare the oxidant-related toxicities of the different oral iron preparations in children with iron deficiency anemia (IDA); the second aim was to investigate the side effects of iron preparations. Seventy-two children with IDA were randomly included in the Fe(2+) group (n = 39) or the Fe(3+) group (n = 33). Some oxidizable substrates (erythrocytes malondialdehyde (MDA), urine 8-isoprostane, and basal and Cu-stimulated-oxidized LDL and antioxidant enzyme (... Abstract

Cited 12 times since 2004 (0.6 per year) source: EuropePMC

European journal of pharmacology, Volume 493, Issue 1-3, 1 1 2004, Pages 161-165 Angiotensin deficiency in mice leads to dilated cardiomyopathy. Walther T, Steendijk P, Westermann D, Hohmann C, Schulze K, Heringer-Walther S, Schultheiss HP, Tschöpe C

To explore the role of angiotensin II, we assessed hemodynamics and cardiac function in angiotensinogen-deficient mice in comparison to wild-type animals. Left ventricular end-diastolic diameter and wall thickness were evaluated by echocardiography and systolic and diastolic left ventricular function by pressure-volume relations using a micro-conductance catheter. Compared to wild-type animals, the angiotensinogen-deficient mice were hypotensive and showed impaired systolic function. The hearts... Abstract

Cited 31 times since 2004 (1.5 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 90, Issue 6, 1 1 2004, Pages 678-684 Cardiovascular response to physical exercise in adult patients after atrial correction for transposition of the great arteries assessed with magnetic resonance imaging. Roest AA, Lamb HJ, van der Wall EE, Vliegen HW, van den Aardweg JG, Kunz P, de Roos A, Helbing WA

Objective: To assess with magnetic resonance imaging (MRI) cardiovascular function in response to exercise in patients after atrial correction of transposition of the great arteries (TGA). Methods: Cardiac function at rest and during submaximal exercise was assessed with MRI in 27 patients with TGA (mean (SD) age 26 (5) years) late (23 (2) years) after atrial correction and in 14 control participants (25 (5) years old). Results: At rest, only right ventricular ejection fraction was significantly... Abstract

Cited 47 times since 2004 (2.2 per year) source: EuropePMC

The American journal of cardiology, Volume 93, Issue 12, 1 1 2004, Pages 1461-1464 Head-to-head comparison between contrast-enhanced magnetic resonance imaging and dobutamine magnetic resonance imaging in men with ischemic cardiomyopathy. Kaandorp TA, Bax JJ, Schuijf JD, Viergever EP, van Der Wall EE, de Roos A, Lamb HJ

Contrast-enhanced magnetic resonance imaging (MRI) can predict functional recovery after revascularization. Segments with small, subendocardial scars have a large likelihood of recovery, and segments with transmural infarction have a small likelihood of recovery. Segments with an intermediate extent of infarction have an intermediate likelihood of recovery, and therefore, additional information is needed. Accordingly, the transmurality of infarction on contrast-enhanced MRI was compared with low... Abstract

Cited 4 times since 2004 (0.2 per year) source: EuropePMC

European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 5, Issue 3, 1 1 2004, Pages 231-236 Aortic valve regurgitation due to cusp aneurysm: a case report. Scholte AJ, Agema WR, Poldermans D, Somer ST, Holman ER, van der Wall EE, Bax JJ

Two-dimensional echocardiography is a valuable tool in visualizing and monitoring aortic valve and root abnormalities. We present a rare case of a patient with massive aortic regurgitation due to cusp aneurysm, which was accurately diagnosed by echocardiography and treated by valve replacement. A complicated course with recurrent aneurysms of the aortic wall after aortic valve replacement was remarkable in this case. Although different possible etiologies could not be determined, endocarditis an... Abstract

Cited 1 times since 2004 (0 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 77, Issue 6, 1 1 2004, Pages 2262-3; author reply 2263 Use of autologous arterial patches for tracheal reconstruction in young infants. Hazekamp MG, Nijdam N

Abstract

Cited 57 times since 2004 (2.7 per year) source: EuropePMC

Circulation research, Volume 95, Issue 1, 20 3 2004, Pages 58-66 Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo. van Weel V, Deckers MM, Grimbergen JM, van Leuven KJ, Lardenoye JH, Schlingemann RO, van Nieuw Amerongen GP, van Bockel JH, van Hinsbergh VW, Quax PH

Therapeutic angiogenesis using vascular endothelial growth factor (VEGF) is considered a promising new therapy for patients with arterial obstructive disease. Clinical improvements observed consist of improved muscle function and regression of rest pain or angina. However, direct evidence for improved vascularization, as evaluated by angiography, is weak. In this study, we report an angiogenesis-independent effect of VEGF on ischemic skeletal muscle, ie, upregulation of myoglobin after VEGF trea... Abstract

Cited 3 times since 2004 (0.1 per year) source: EuropePMC

Intensive care medicine, Volume 30, Issue 7, 4 1 2004, Pages 1370-1376 Transcardiac conductance for continuous measurement of left ventricular volume: validation vs. angiography in patients. Staal EM, Baan J, Jukema JW, van der Wall EE, Steendijk P

Objective: To test the feasibility of the transcardiac conductance (TCC) method for continuous, on-line measurement of absolute left ventricular (LV) volume and to validate the method by comparison with biplane angiography. Design and setting: Prospective clinical feasibility and validation study in a cardiac catheterization laboratory in a university hospital. Patients and interventions: Ten patients scheduled for electrophysiological studies ( n=5), percutaneous transluminal coronary angioplas... Abstract

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 12, Issue 5, 1 1 2004, Pages 255-256 Recommendations for pacemaker implantation for the treatment of atrial tachyarrhythmias and resynchronisation therapy for heart failure. Wijffels MC, Bootsma M, van Erven L, Zeppenfeld K, Schalij MJ, van Hemel NM

Abstract

Cited 13 times since 2004 (0.6 per year) source: EuropePMC

Pathologie-biologie, Volume 52, Issue 4, 1 1 2004, Pages 186-195 Genetic predictive factors in restenosis. Monraats PS, R P Agema W, Jukema JW

Restenosis is still the main drawback of percutaneous transluminal coronary angioplasty (PTCA). It is thought to be a multifactorial process where recoil of the vessel, neointimal proliferation and thrombus formation are thought to play a role. Until now it has proven difficult to predict restenosis on clinical and procedural grounds, however, genetic epidemiology might provide more insights. In this review several genetic variables, i.e. polymorphisms that were determined in relation to resteno... Abstract

Cited 12 times since 2004 (0.6 per year) source: EuropePMC

European journal of pharmacology, Volume 491, Issue 2-3, 1 1 2004, Pages 173-179 Hemodynamic characterization of left ventricular function in experimental coxsackieviral myocarditis: effects of carvedilol and metoprolol. Tschöpe C, Westermann D, Steendijk P, Noutsias M, Rutschow S, Weitz A, Schwimmbeck PL, Schultheiss HP, Pauschinger M

Background: Carvedilol, a vasodilating nonselective beta-adrenoceptor antagonist, but not metoprolol, a selective beta1-adrenoceptor antagonist, has been shown to increase the production of cardiac antiinflammatory cytokines in experimental myocarditis. However, the hemodynamic consequences of these differences had not been investigated until today. Therefore, we determined the effects of carvedilol and metoprolol on left ventricular function in a murine model of coxsackievirus B3 (CVB3)-induced... Abstract

Cited 1 times since 2004 (0 per year) source: EuropePMC

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 12, Issue 5, 1 1 2004, Pages 214-222 Recommendations and cardiological evaluation of athletes with arrhythmias: Part 2. Hoogsteen J, Bennekers JH, van der Wall EE, van Hemel NM, Wilde AA, Crijns HJ, Gorgels AP, Smeets JL, Hauer RN, Jordaens JL, Schalij MJ

Confronted with a competitive or recreational athlete, the physician has to discriminate between benign, paraphysiological and pathological arrhythmias. Benign arrhythmias do not represent a risk for SCD, nor do they induce haemodynamic consequences during athletic activities. These arrhythmias are not markers for heart disease. Paraphysiological arrhythmias are related to athletic performance. Long periods of endurance training induce changes in rhythm, conduction and repolarisation. These chan... Abstract

Cited 48 times since 2004 (2.3 per year) source: EuropePMC

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, Volume 13, Issue 4, 1 1 2004, Pages 735-745 A cardiac-specific health-related quality of life module for young adults with congenital heart disease: development and validation. Kamphuis M, Zwinderman KH, Vogels T, Vliegen HW, Kamphuis RP, Ottenkamp J, Verloove-Vanhorick SP, Bruil J

This study represents the development and validation of a cardiac-specific module of the generic health-related quality of life (HRQoL) instrument, the TAAQOL (TNO/AZL Adult Quality Of Life), for young adults with congenital heart disease (CHD). Items were selected based on literature, an explorative previous study in CHD patients, interviews with patients, and the advice of experts. The newly developed Congenital Heart Disease-TNO/AZL Adult Quality of Life (CHD-TAAQOL) was tested in 156 patient... Abstract

Cited 254 times since 2004 (12 per year) source: EuropePMC

Journal of cardiovascular electrophysiology, Volume 15, Issue 5, 1 1 2004, Pages 544-549 Relationship between QRS duration and left ventricular dyssynchrony in patients with end-stage heart failure. Bleeker GB, Schalij MJ, Molhoek SG, Verwey HF, Holman ER, Boersma E, Steendijk P, Van Der Wall EE, Bax JJ

Introduction: Patients with end-stage heart failure and a wide QRS complex are considered candidates for cardiac resynchronization therapy (CRT). However, 20% to 30% of patients do not respond to CRT. Lack of left ventricular dyssynchrony may explain the nonresponse. Accordingly, we evaluated the presence of left ventricular dyssynchrony using tissue Doppler imaging (TDI) in 90 consecutive patients with heart failure. Methods and results: Ninety patients with severe heart failure (left ventricul... Abstract

Cited 14 times since 2004 (0.7 per year) source: EuropePMC

Heart rhythm, Volume 1, Issue 1, 1 1 2004, Pages 51-57 Standardized screening and treatment of patients with life-threatening arrhythmias: the Leiden out-of-hospital cardiac arrest evaluation study. van der Burg AE, Bax JJ, Boersma E, van Erven L, Bootsma M, van der Wall EE, Schalij MJ

Objectives: The aim of this study was to evaluate the effect of a systematic screening/treatment protocol on outcome in patients after aborted sudden death. Background: Patients after aborted sudden death are at high risk for recurrent events. In this regard, systematic screening is mandatory to reveal the underlying etiology, to detect and subsequently treat reversible causes, and to establish patient-tailored antiarrhythmic treatment. Methods: A total of 417 consecutive patients after aborted... Abstract

Cited 9 times since 2004 (0.4 per year) source: EuropePMC

The American journal of cardiology, Volume 93, Issue 10, 1 1 2004, Pages 1298-1302 Anatomical observations of the pulmonary veins with intracardiac echocardiography and hemodynamic consequences of narrowing of pulmonary vein ostial diameters after radiofrequency catheter ablation of atrial fibrillation. Jongbloed MR, Bax JJ, Zeppenfeld K, van der Wall EE, Schalij MJ

Intracardiac echocardiography was used to explore pulmonary venous (PV) anatomy and to monitor PV stenosis in 31 patients referred for radiofrequency catheter ablation at PV ostia. Interindividual variations in PV anatomy and insertion in the left atrium were observed. Narrowing of PV ostia after radiofrequency catheter ablation did not produce significant hemodynamic changes. Abstract