Research

Publications

Below you can find a list of our published research.

9396 results

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 29, Issue 4, 21 3 2021, Pages 2011-2012 Automated artificial intelligence quantification of aortic atherosclerotic calcifications by 18F-sodium fluoride PET/CT. Ng ACT, van Rosendael AR, Bax JJ

Abstract

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

The journal of vascular access, Volume 24, Issue 2, 19 3 2021, Pages 277-283 Clinical nurses' knowledge and practices on routine care related to the prevention of complications of peripheral intravenous therapy: A cross-sectional study. Yilmaz DU, Yilmaz D, Karaman D

Aim: The aim of this descriptive and cross-sectional study was to determine the knowledge and practices of nurses related to the prevention of peripheral intravenous therapy (PIT) complications, and to identify the influencing factors. Methods: The study adopted a cross-sectional and descriptive design and was conducted between April and August of 2018 with a total of 214 clinical nurses. The data collection tools employed were a 12-item sociodemographic questionnaire and a 16-item questionnaire... Abstract

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 19 3 2021, Pages 689375 Existence and Quality of Data on Control Programs for EU Non-regulated Cattle Diseases: Consequences for Estimation and Comparison of the Probability of Freedom From Infection. Rapaliute E, van Roon A, van Schaik G, Santman-Berends I, Koleci X, Mincu M, Gethmann J, Conrady B, Knific T, Hodnik JJ, Berezowski J, Carmo LP, Madouasse A, Tarpai A, Gerilovych A, Malakauskas A, Sekovska B, Fourichon C, Kalaitzakis E, Roch FF, Houe H, Dudek K, Mõtus K, Ózsvári L, Costa L, Guelbenzu-Gonzalo M, Henry MK, Alishani M, Pozzato N, Hopp P, Juste R, Strain S, Mandelik R, Vilček Š, Autio T, Tamminen LM, Faverjon C

Some European countries have successfully implemented country-specific control programs (CPs) for infectious cattle diseases that are not regulated or are regulated only to a limited extent at the European Union (EU) level. Examples of such diseases include bovine viral diarrhea (BVD), infectious bovine rhinotracheitis (IBR), and Johne's disease (JD). The CPs vary between countries in the design and quality of collected data as well as methods used to detect infection and estimate prevalenc... Abstract

Cited 2 times since 2021 (0.5 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 14, Issue 8, 19 3 2021, Pages e009777 Anatomical Characteristics of the Left Atrium and Left Atrial Appendage in Relation to the Risk of Stroke in Patients With Versus Without Atrial Fibrillation. Smit JM, Simon J, El Mahdiui M, Szaraz L, van Rosendael PJ, Kolassváry M, Szilveszter B, Delgado V, Merkely B, Maurovich-Horvat P, Bax JJ

[Figure: see text]. Abstract

Cited 27 times since 2021 (7.3 per year) source: EuropePMC

Progress in retinal and eye research, Volume 87, 17 3 2021, Pages 100994 Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease. Brinks J, van Dijk EHC, Klaassen I, Schlingemann RO, Kielbasa SM, Emri E, Quax PHA, Bergen AA, Meijer OC, Boon CJF

The choroid is a key player in maintaining ocular homeostasis and plays a role in a variety of chorioretinal diseases, many of which are poorly understood. Recent advances in the field of single-cell RNA sequencing have yielded valuable insights into the properties of choroidal endothelial cells (CECs). Here, we review the role of the choroid in various physiological and pathophysiological mechanisms, focusing on the role of CECs. We also discuss new insights regarding the phenotypic properties... Abstract

Cited 3 times since 2021 (0.8 per year) source: EuropePMC

Frontiers in cardiovascular medicine, Volume 8, 16 3 2021, Pages 682785 Predictive Added Value of Selected Plasma Lipids to a Re-estimated Minimal Risk Tool. Bodini A, Michelucci E, Di Giorgi N, Caselli C, Signore G, Neglia D, Smit JM, Scholte AJHA, Mincarone P, Leo CG, Pelosi G, Rocchiccioli S

Background: Lipidomics is emerging for biomarker discovery in cardiovascular disease, and circulating lipids are increasingly incorporated in risk models to predict cardiovascular events. Moreover, specific classes of lipids, such as sphingomyelins, ceramides, and triglycerides, have been related to coronary artery disease (CAD) severity and plaque characteristics. To avoid unnecessary testing, it is important to identify individuals at low CAD risk. The only pretest model available so far to ru... Abstract

Cited 25 times since 2021 (6.8 per year) source: EuropePMC

European journal of human genetics : EJHG, Volume 30, Issue 10, 15 3 2021, Pages 1105-1113 Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone). Matic M, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Houwink EJF, Mulder H, Rongen GAPJM, Weide JV, Wilffert B, Swen JJ, Guchelaar HJ, Deneer VHM, van Schaik RHN

The current Dutch Pharmacogenetics Working Group (DPWG) guideline, describes the gene-drug interaction between CYP2D6 and the opioids codeine, tramadol and oxycodone. CYP2D6 genotype is translated into normal metaboliser (NM), intermediate metaboliser (IM), poor metaboliser (PM) or ultra-rapid metaboliser (UM). Codeine is contraindicated in UM adults if doses >20 mg every 6 h (q6h), in children ≥12 years if doses >10 mg q6h, or with additional risk factors. In PMs, an alternative analgesic... Abstract

Cited 2 times since 2021 (0.5 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 15 3 2021, Pages 661459 Added Value of Meat Inspection Data for Monitoring of Dairy Cattle Health in the Netherlands. Veldhuis AMB, Smits D, Bouwknegt M, Worm H, van Schaik G

Meat inspection records of one large cattle slaughterhouse were analyzed to evaluate the added value of slaughterhouse data for cattle health surveillance in the Netherlands. Data were available from January 2015 to September 2018, consisting of 467,361 meat inspection records. Analyses included (1) an assessment of the representativeness of the cattle herds in the slaughterhouse data in relation to the cattle herd population in the Netherlands, and (2) multivariable analyses to quantify associa... Abstract

Cited 12 times since 2021 (3.3 per year) source: EuropePMC

Microbiology spectrum, Volume 9, Issue 1, 14 2 2021, Pages e0005821 Spread of Carbapenem-Resistant Klebsiella pneumoniae in an Intensive Care Unit: A Whole-Genome Sequence-Based Prospective Observational Study. Wei L, Wu L, Wen H, Feng Y, Zhu S, Liu Y, Tang L, Doughty E, van Schaik W, McNally A, Zong Z

The aim of this study was to determine the contribution of the contamination of the health care environment in the acquisition of carbapenem-resistant Klebsiella pneumoniae (CRKP) in a CRKP-prevalent setting. We performed a 3-month prospective study in a 20-bed medical intensive care unit (ICU) by collecting rectal/oral swabs from patients within 3 days of ICU admission and weekly thereafter. We also comprehensively sampled the beds and rooms of patients and instruments for patient care every we... Abstract

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 14 2 2021, Pages 671873 An Overview of Current Approaches and Challenges to the Control of Endemic Infectious Cattle Diseases in Albania. Koleci X, Lilo A, Papa S, Margariti K, van Roon A, Santman-Berends I, van Schaik G, Hodnik JJ, Strain S, Guelbenzu-Gonzalo M, Karalliu E

Agriculture is an important production sector in Albania that makes a significant contribution to the gross domestic product (GDP) and employment. The livestock sector contributes more than half of the agricultural GDP. The Albanian cattle population represents 50% of the total livestock units and accounts for 85% of the national milk production, the rest being supplied by small ruminants. Cattle productivity, health and welfare are hindered by infectious diseases, some of which are also transmi... Abstract

Cited 5 times since 2021 (1.4 per year) source: EuropePMC

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 30, Issue 1, 14 2 2021, Pages 47-57 The challenge of choosing in cardiovascular risk management. Hoogeveen RM, Hanssen NMJ, Brouwer JR, Mosterd A, Tack CJ, Kroon AA, de Borst GJ, Ten Berg J, van Trier T, van Lennep JR, Liem A, Serné E, Visseren FLJ, Cornel JH, Peters RJG, Jukema JW, Stroes ESG, PANORAMA working group

Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. For many years guidelines have listed optimal preventive therapy. More recently, novel therapeutic options have broadened the options for state-of-the-art CV risk management (CVRM). In the majority of patients with CVD, risk lowering can be achieved by utilising standard preventive medication combined with lifestyle modifications. In a minority of patients, add-on therapies should be considered to further reduce... Abstract

Cited 5 times since 2021 (1.4 per year) source: EuropePMC

EJVES vascular forum, Volume 52, 14 2 2021, Pages 26-29 Ruptured Aneurysm of the Common Iliac Artery Caused by Brucella melitensis: A Case Report. Willems SA, Buntinx M, Gelinck LBS, van Schaik J, Eefting D

Introduction: Brucella is a genus of aerobic Gram negative bacteria that causes the disease brucellosis. It is considered a zoonotic infection transmitted to humans by ingestion of unpasteurised dairy products. Although aortic involvement is rarely seen, it can be a life threatening complication of this disease. This case report describes a ruptured aneurysm of the common iliac artery (CIA) due to secondary infection by Brucella melitensis. Report: A 79 year old man with a known isolated aneurys... Abstract

Cited 5 times since 2021 (1.4 per year) source: EuropePMC

mSystems, Volume 6, Issue 4, 13 2 2021, Pages e0013721 Metagenome-Wide Analysis of Rural and Urban Surface Waters and Sediments in Bangladesh Identifies Human Waste as a Driver of Antibiotic Resistance. McInnes RS, Uz-Zaman MH, Alam IT, Ho SFS, Moran RA, Clemens JD, Islam MS, van Schaik W

In many low- and middle-income countries, antibiotic-resistant bacteria spread in the environment due to inadequate treatment of wastewater and the poorly regulated use of antibiotics in agri- and aquaculture. Here, we characterized the abundance and diversity of antibiotic-resistant bacteria and antibiotic resistance genes in surface waters and sediments in Bangladesh through quantitative culture of extended-spectrum beta-lactamase (ESBL)-producing coliforms and shotgun metagenomics. Samples we... Abstract

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

Transboundary and emerging diseases, Volume 69, Issue 4, 12 2 2021, Pages 2008-2020 The effectiveness of bovine tuberculosis surveillance in Dutch badgers. Orrico M, van Schaik G, Koets A, van den Broek J, Montizaan M, La Haye M, Rijks JM

Countries survey wildlife for bovine tuberculosis (bTB) to ensure case detection or to ascertain a high probability of freedom from bTB in wildlife. The Eurasian badger (Meles meles) is a potential bTB reservoir host. Between 2008 and 2019, 282 badgers were examined post-mortem in the context of general wildlife disease and targeted bTB surveillance programmes in the Netherlands, and no bTB cases were detected. However, it was unclear how effective this surveillance effort was to demonstrate fre... Abstract

Cited 24 times since 2021 (6.5 per year) source: EuropePMC

Nature reviews. Cardiology, Volume 18, Issue 12, 12 2 2021, Pages 824-837 Effects of fatty acids on T cell function: role in atherosclerosis. Reilly NA, Lutgens E, Kuiper J, Heijmans BT, Jukema JW

T cells are among the most common cell types present in atherosclerotic plaques and are increasingly being recognized as a central mediator in atherosclerosis development and progression. At the same time, triglycerides and fatty acids have re-emerged as crucial risk factors for atherosclerosis. Triglycerides and fatty acids are important components of the milieu to which the T cell is exposed from the circulation to the plaque, and increasing evidence shows that fatty acids influence T cell fun... Abstract

Cited 21 times since 2021 (5.7 per year) source: EuropePMC

BMJ open, Volume 11, Issue 7, 12 2 2021, Pages e050519 Effectiveness of contact tracing apps for SARS-CoV-2: a rapid systematic review. Jenniskens K, Bootsma MCJ, Damen JAAG, Oerbekke MS, Vernooij RWM, Spijker R, Moons KGM, Kretzschmar MEE, Hooft L

Objective: To systematically review evidence on effectiveness of contact tracing apps (CTAs) for SARS-CoV-2 on epidemiological and clinical outcomes. Design: Rapid systematic review. Data sources: EMBASE (OVID), MEDLINE (PubMed), BioRxiv and MedRxiv were searched up to 28 October 2020. Study selection: Studies, both empirical and model-based, assessing effect of CTAs for SARS-CoV-2 on reproduction number (R), total number of infections, hospitalisation rate, mortality rate, and other epidemiolog... Abstract

Cited 6 times since 2021 (1.6 per year) source: EuropePMC

Pharmaceutics, Volume 13, Issue 7, 10 2 2021, Pages 1055 Kinetic and Microhydrodynamic Modeling of Fenofibrate Nanosuspension Production in a Wet Stirred Media Mill. Guner G, Yilmaz D, Bilgili E

This study examined the impact of stirrer speed and bead material loading on fenofibrate particle breakage during wet stirred media milling (WSMM) via three kinetic models and a microhydrodynamic model. Evolution of median particle size was tracked via laser diffraction during WSMM operating at 3000-4000 rpm with 35-50% (v/v) concentration of polystyrene or zirconia beads. Additional experiments were performed at the center points of the above conditions, as well as outside the range of these co... Abstract

Cited 19 times since 2021 (5.1 per year) source: EuropePMC

Brain, behavior and evolution, Volume 96, Issue 1, 9 2 2021, Pages 1-12 A Farewell to the Encephalization Quotient: A New Brain Size Measure for Comparative Primate Cognition. van Schaik CP, Triki Z, Bshary R, Heldstab SA

Both absolute and relative brain sizes vary greatly among and within the major vertebrate lineages. Scientists have long debated how larger brains in primates and hominins translate into greater cognitive performance, and in particular how to control for the relationship between the noncognitive functions of the brain and body size. One solution to this problem is to establish the slope of cognitive equivalence, i.e., the line connecting organisms with an identical bauplan but different body siz... Abstract

Cited 27 times since 2021 (7.3 per year) source: EuropePMC

Frontiers in genetics, Volume 12, 8 2 2021, Pages 711943 CYP3A4∗22 Genotyping in Clinical Practice: Ready for Implementation? Mulder TAM, van Eerden RAG, de With M, Elens L, Hesselink DA, Matic M, Bins S, Mathijssen RHJ, van Schaik RHN

Cytochrome P450 3A4 (CYP3A4) is the most important drug metabolizing enzyme in the liver, responsible for the oxidative metabolism of ∼50% of clinically prescribed drugs. Therefore, genetic variation in CYP3A4 could potentially affect the pharmacokinetics, toxicity and clinical outcome of drug treatment. Thus far, pharmacogenetics for CYP3A4 has not received much attention. However, the recent discovery of the intron 6 single-nucleotide polymorphism (SNP) rs35599367C > T, encoding the CYP3A4∗... Abstract

Cited 17 times since 2021 (4.6 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 8 2 2021, Pages 620998 Assessment of Evaluation Tools for Integrated Surveillance of Antimicrobial Use and Resistance Based on Selected Case Studies. Sandberg M, Hesp A, Aenishaenslin C, Bordier M, Bennani H, Bergwerff U, Chantziaras I, De Meneghi D, Ellis-Iversen J, Filippizi ME, Mintiens K, Nielsen LR, Norström M, Tomassone L, van Schaik G, Alban L

Regular evaluation of integrated surveillance for antimicrobial use (AMU) and resistance (AMR) in animals, humans, and the environment is needed to ensure system effectiveness, but the question is how. In this study, six different evaluation tools were assessed after being applied to AMU and AMR surveillance in eight countries: (1) ATLASS: the Assessment Tool for Laboratories and AMR Surveillance Systems developed by the Food and Agriculture Organization (FAO) of the United Nations, (2) ECoSur:... Abstract