6190 results
Cited 1 times since 2023 (0.5 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 10, 26 4 2023, Pages 1094969
Microinvasive mitral valve surgery: Current status and status quo.
Tomšič A, Klautz RJM, Borger MA, Palmen M
Surgical mitral valve repair, performed either through median sternotomy or minimal invasive approach, presents the gold standard treatment for degenerative mitral valve disease. In dedicated centres, high repair and low complication rates have been established with excellent valve repair durability. Recently, new techniques have been introduced, that allow mitral valve repair to be performed through small surgical incisions and while avoiding cardio-pulmonary bypass. These new techniques, howev...
Abstract
Cited 4 times since 2023 (2 per year)
source: EuropePMC
The Canadian journal of cardiology,
Volume 39, Issue 10, 26 4 2023, Pages 1315-1324
Lipoprotein(a) and the Effect of Alirocumab on Revascularization After Acute Coronary Syndrome.
Steg PG, Szarek M, Valgimigli M, Islam S, Zeiher AM, Bhatt DL, Bittner VA, Chiang CE, Diaz R, Goodman SG, Gotcheva N, Harrington RA, Jukema JW, Kim HS, Kim SH, Morais J, Pordy R, Scemama M, White HD, Schwartz GG, ODYSSEY OUTCOMES Investigators
Background: Many patients require revascularization after index acute coronary syndrome (ACS). Lipoprotein(a) is thought to play a pathogenic role in atherothrombosis. In ODYSSEY OUTCOMES, alirocumab reduced major adverse cardiovascular events after ACS, with greater reduction among those with higher lipoprotein(a) levels. We explored whether risk of revascularization after ACS was modified by the level of lipoprotein(a) and treatment with alirocumab or placebo. Methods: In ODYSSEY OUTCOMES alir...
Abstract
Cited 1 times since 2023 (0.5 per year)
source: EuropePMC
Terapevticheskii arkhiv,
Volume 95, Issue 3, 26 4 2023, Pages 248-254
[Difficult case of differential diagnosis of partial lung atelectasis. Case report].
Gordeeva OM, Egorova AD, Chesalina YO, Gretcov EM, Semenova LA, Karpina NL, Sivokozov IV
In December 2018 the patient over 60 years old sought medical help with complaints of persistent cough. Based on computed tomography data there were identified the sings (symptoms) of right lung lower lobe atelectasis. To run this patient diagnostics there were performed 6 bronchoscopies narrowed down by bronchi checks up only and described the right lung central cancer picture. At the same time the biopsy taken during one of the bronchoscopies appeared non informative. Fine needle biopsy of med...
Abstract
Cited 8 times since 2023 (4 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 24, Issue 9, 25 4 2023, Pages 7818
Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation.
Inia JA, Stokman G, Pieterman EJ, Morrison MC, Menke AL, Verschuren L, Caspers MPM, Giera M, Jukema JW, van den Hoek AM, Princen HMG
Patients with metabolic syndrome are often prescribed statins to prevent the development of cardiovascular disease. Conversely, data on their effects on non-alcoholic steatohepatitis (NASH) are lacking. We evaluated these effects by feeding APOE*3-Leiden mice a Western-type diet (WTD) with or without atorvastatin to induce NASH and hepatic fibrosis. Besides the well-known plasma cholesterol lowering (-30%) and anti-atherogenic effects (severe lesion size -48%), atorvastatin significantly reduced...
Abstract
Cited 5 times since 2023 (2.5 per year)
source: EuropePMC
The Science of the total environment,
Volume 883, 25 4 2023, Pages 163599
Capturing the SARS-CoV-2 infection pyramid within the municipality of Rotterdam using longitudinal sewage surveillance.
de Graaf M, Langeveld J, Post J, Carrizosa C, Franz E, Izquierdo-Lara RW, Elsinga G, Heijnen L, Been F, van Beek J, Schilperoort R, Vriend R, Fanoy E, de Schepper EIT, Koopmans MPG, Medema G
Despite high vaccination rates in the Netherlands, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to circulate. Longitudinal sewage surveillance was implemented along with the notification of cases as two parts of the surveillance pyramid to validate the use of sewage for surveillance, as an early warning tool, and to measure the effect of interventions. Sewage samples were collected from nine neighborhoods between September 2020 and November 2021. Comparative analysis an...
Abstract
Cited 4 times since 2023 (2 per year)
source: EuropePMC
American heart journal,
Volume 262, 20 3 2023, Pages 55-65
Validation of the ARIC prediction model for sudden cardiac death in the European population: The ESCAPE-NET project.
Welten SJGC, Remmelzwaal S, Blom MT, van der Heijden AA, Nijpels G, Tan HL, van Valkengoed I, Empana JP, Jouven X, Ågesen FN, Warming PE, Tfelt-Hansen J, Prescott E, Jabbari R, Elders PJM, for ESCAPE-NET investigators,
Background: Sudden cardiac death is responsible for 10% to 20% of all deaths in Europe. The current study investigates how well the risk of sudden cardiac death can be predicted. To this end, we validated a previously developed prediction model for sudden cardiac death from the Atherosclerosis Risk in Communities study (USA). Methods: Data from participants of the Copenhagen City Heart Study (CCHS) (n=9988) was used to externally validate the previously developed prediction model for sudden card...
Abstract
Cited 5 times since 2023 (2.5 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 10, Issue 4, 20 3 2023, Pages 180
Cardiac Fibrosis and Innervation State in Uncorrected and Corrected Transposition of the Great Arteries: A Postmortem Histological Analysis and Systematic Review.
Engele LJ, van der Palen RLF, Egorova AD, Bartelings MM, Wisse LJ, Glashan CA, Kiès P, Vliegen HW, Hazekamp MG, Mulder BJM, Ruiter MC, Bouma BJ, Jongbloed MRM
In the transposition of the great arteries (TGA), alterations in hemodynamics and oxygen saturation could result in fibrotic remodeling, but histological studies are scarce. We aimed to investigate fibrosis and innervation state in the full spectrum of TGA and correlate findings to clinical literature. Twenty-two human postmortem TGA hearts, including TGA without surgical correction (n = 8), after Mustard/Senning (n = 6), and arterial switch operation (ASO, n = 8), were studied. In newborn uncor...
Abstract
The American journal of medicine,
Volume 136, Issue 7, 15 3 2023, Pages 720-721
Corrigendum to 'Integrating Coronary Atherosclerosis Burden and Progression with Coronary Artery Disease Risk Factors to Guide Therapeutic Decision Making' The American Journal of Medicine 136:03 (2023); 260-269.e7.
Freeman AM, Raman SV, Aggarwal M, Maron DJ, Bhatt DL, Parwani P, Osborne J, Earls JP, Min JK, Bax JJ, Shapiro MD
Abstract
Cited 6 times since 2023 (2.9 per year)
source: EuropePMC
Cancers,
Volume 15, Issue 8, 14 2 2023, Pages 2297
Radiomics of Tumor Heterogeneity in <sup>18</sup>F-FDG-PET-CT for Predicting Response to Immune Checkpoint Inhibition in Therapy-Naïve Patients with Advanced Non-Small-Cell Lung Cancer.
Ventura D, Schindler P, Masthoff M, Görlich D, Dittmann M, Heindel W, Schäfers M, Lenz G, Wardelmann E, Mohr M, Kies P, Bleckmann A, Roll W, Evers G
We aimed to evaluate the predictive and prognostic value of baseline 18F-FDG-PET-CT (PET-CT) radiomic features (RFs) for immune checkpoint-inhibitor (CKI)-based first-line therapy in advanced non-small-cell lung cancer (NSCLC) patients. In this retrospective study 44 patients were included. Patients were treated with either CKI-monotherapy or combined CKI-based immunotherapy-chemotherapy as first-line treatment. Treatment response was assessed by the Response Evaluation Criteria in Solid Tumors...
Abstract
Cited 5 times since 2023 (2.4 per year)
source: EuropePMC
Atherosclerosis,
Volume 384, 14 2 2023, Pages 117123
Sex-specific differences in cytokine signaling pathways in circulating monocytes of cardiovascular disease patients.
Lu C, Donners MMPC, Karel J, de Boer H, van Zonneveld AJ, den Ruijter H, Jukema JW, Kraaijeveld A, Kuiper J, Pasterkamp G, Cavill R, Perales-Patón J, Ferrannini E, Goossens P, Biessen EAL
Background and aims: This study aims to identify sex-specific transcriptional differences and signaling pathways in circulating monocytes contributing to cardiovascular disease. Methods and results: We generated sex-biased gene expression signatures by comparing male versus female monocytes of coronary artery disease (CAD) patients (n = 450) from the Center for Translational Molecular Medicine-Circulating Cells Cohort. Gene set enrichment analysis demonstrated that monocytes from female CAD pati...
Abstract
Cited 2 times since 2023 (1 per year)
source: EuropePMC
Musculoskeletal science & practice,
Volume 65, 14 2 2023, Pages 102764
Comparison between two patient-reported outcome measures for patients with cervical radiculopathy: A think-aloud study.
Thoomes E, de Graaf M, Gallina A, Falla D, Stathi A
Background: The Cervical Radiculopathy Impact Scale (CRIS) and Patient Specific Functional Scale 2.0 (PSFS 2.0) are patient-reported outcome measures (PROMs) used to assess activity limitations in patients with cervical radiculopathy (CR). This study a) compared the CRIS subscale 3 and the PSFS 2.0 in patients with CR with respect to completeness and patient preference, b) established the correlation between both PROMs in assessing the individual patient's level of functional limitations an...
Abstract
Eye (London, England),
Volume 37, Issue 16, 12 2 2023, Pages 3442-3445
A prospective long-term evaluation of the ocular findings of children followed with the diagnosis of multisystem inflammatory syndrome (long-term evaluation of ocular findings following MIS-C).
Kaya-Guner E, Sahin A, Ekemen-Keles Y, Karadag-Oncel E, Kara-Aksay A, Yilmaz D
Background/objectives: The most frequently reported ocular finding in the acute phase of the multisystem inflammatory syndrome in children (MIS-C), is conjunctivitis. More rarely, punctuate epitheliopathy, anterior uveitis and optic disc oedema can be seen. We aimed to investigate the acute and long-term ocular effects of MIS-C. Subjects/methods: Cases aged 1 month to 18 years who were diagnosed with MIS-C between January 2022 and June 2022 in the Department of Pediatric Infectious Diseases in o...
Abstract
The Pediatric infectious disease journal,
Volume 42, Issue 8, 11 2 2023, Pages e316-e318
Isolated Subcutaneous Abscess: A Rare Presentation of Extrapulmonary Tuberculosis.
Sahin A, Kara-Aksay A, Bicmen C, Belkaya S, Kaya A, Yilmaz D
Abstract
Cited 15 times since 2023 (7.3 per year)
source: EuropePMC
BMC biology,
Volume 21, Issue 1, 11 2 2023, Pages 76
Genome-wide association reveals host-specific genomic traits in Escherichia coli.
Tiwari SK, van der Putten BCL, Fuchs TM, Vinh TN, Bootsma M, Oldenkamp R, La Ragione R, Matamoros S, Hoa NT, Berens C, Leng J, Álvarez J, Ferrandis-Vila M, Ritchie JM, Fruth A, Schwarz S, Domínguez L, Ugarte-Ruiz M, Bethe A, Huber C, Johanns V, Stamm I, Wieler LH, Ewers C, Fivian-Hughes A, Schmidt H, Menge C, Semmler T, Schultsz C
Background: Escherichia coli is an opportunistic pathogen which colonizes various host species. However, to what extent genetic lineages of E. coli are adapted or restricted to specific hosts and the genomic determinants of such adaptation or restriction is poorly understood. Results: We randomly sampled E. coli isolates from four countries (Germany, UK, Spain, and Vietnam), obtained from five host species (human, pig, cattle, chicken, and wild boar) over 16 years, from both healthy and diseased...
Abstract
Cited 2 times since 2023 (1 per year)
source: EuropePMC
Clinical oral implants research,
Volume 34, Issue 6, 10 2 2023, Pages 582-590
Anti-Apoptotic and Pro-Apoptotic Bcl-2 Family Proteins in Peri-Implant Diseases.
Yilmaz D, Gürsoy M, Gürsoy UK
Objectives: Intrinsic apoptosis, which is regulated by Bcl-2 family proteins, has an important role in chronic inflammatory diseases. The aim of the study was to identify the tissue levels and ratios of anti- and pro-apoptotic Bcl-2 family proteins in peri-implant diseases. Materials and methods: Twenty-three individuals with peri-implant mucositis, 25 individuals with peri-implantitis, and 24 controls were included. The following clinical parameters were recorded: keratinized mucosa width, modi...
Abstract
Cited 1 times since 2023 (0.5 per year)
source: EuropePMC
European heart journal. Case reports,
Volume 7, Issue 4, 6 1 2023, Pages ytad176
Genetic variant in the <i>BRAF</i> gene compatible with Noonan spectrum disorders in an adult Fontan patient with refractory protein losing enteropathy: a follow-up report.
Nederend M, Stoger JL, Egorova AD, Barge-Schaapveld DQCM, Jongbloed MRM
Background: Patients with a univentricular heart form a morphological heterogenous group of patients at the most severe end of the congenital heart disease (CHD) spectrum. Over the past decades, more awareness and knowledge has been raised on the genetic contributions to CHD. To date, only a limited number of genes have been identified in the hypoplastic heart, mainly in left-sided hypoplasia. There is still much more to be elucidated in this field. Case summary: Here, we present a follow-up rep...
Abstract
Cited 8 times since 2023 (3.9 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 94, 5 1 2023, Pages 178-185
Nutcracker Syndrome: Challenges in Diagnosis and Surgical Treatment.
Dieleman F, Hamming JF, Erben Y, van der Vorst JR
Background: Nutcracker syndrome (NCS) is an uncommon syndrome that presents with signs and symptoms caused by compression of the left renal vein (LRV), whereas 'nutcracker phenomenon' is solely used to refer to the anatomical configuration without clinical symptoms. Treatment for NCS may include nonoperative management, open surgical intervention, and in some instances endovascular stenting. We present a single-center retrospective case series of patients who presented with NCS managed...
Abstract
Cited 1 times since 2023 (0.5 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 10, Issue 4, 5 1 2023, Pages 156
Fluid Overload in Pediatric Univentricular Patients Undergoing Fontan Completion.
Luppes VAC, Willems A, Hazekamp MG, Blom NA, Ten Harkel ADJ
Background: Fluid overload (FO) is known to occur frequently after pediatric cardiac surgery and is associated with morbidity and mortality. Fontan patients are at risk to develop FO due to their critical fluid balance. Furthermore, they need an adequate preload in order to maintain adequate cardiac output. This study aimed to identify FO in patients undergoing Fontan completion and the impact of FO on pediatric intensive care unit (PICU) length of stay (LOS) and cardiac events, defined as death...
Abstract
Cited 23 times since 2023 (11.1 per year)
source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 18, Issue 16, 3 1 2023, Pages e1307-e1327
Computed tomographic angiography in coronary artery disease.
Serruys PW, Kotoku N, Nørgaard BL, Garg S, Nieman K, Dweck MR, Bax JJ, Knuuti J, Narula J, Perera D, Taylor CA, Leipsic JA, Nicol ED, Piazza N, Schultz CJ, Kitagawa K, Bruyne B, Collet C, Tanaka K, Mushtaq S, Belmonte M, Dudek D, Zlahoda-Huzior A, Tu S, Wijns W, Sharif F, Budoff MJ, Mey J, Andreini D, Onuma Y
Coronary computed tomographic angiography (CCTA) is becoming the first-line investigation for establishing the presence of coronary artery disease and, with fractional flow reserve (FFRCT), its haemodynamic significance. In patients without significant epicardial obstruction, its role is either to rule out atherosclerosis or to detect subclinical plaque that should be monitored for plaque progression/regression following prevention therapy and provide risk classification. Ischaemic non-obstructi...
Abstract
Cited 5 times since 2023 (2.4 per year)
source: EuropePMC
JAMA network open,
Volume 6, Issue 4, 3 1 2023, Pages e239973
Time Trends in Patient Characteristics, Anticoagulation Treatment, and Prognosis of Incident Nonvalvular Atrial Fibrillation in the Netherlands.
Chen Q, Toorop MMA, Tops LF, Lijfering WM, Cannegieter SC
Importance: The temporal trend in adverse events regarding stroke prevention for nonvalvular atrial fibrillation (NVAF) in the direct oral anticoagulant (DOAC) era was rarely investigated comprehensively, especially taking into account potential changes in patient characteristics and anticoagulation treatment. Objective: To investigate time trends in patient characteristics, anticoagulation treatment, and prognosis of patients with incident NVAF in the Netherlands. Design, setting, and participa...
Abstract
