6131 results
Cited 16 times since 2019 (2.6 per year)
source: EuropePMC
Neurology,
Volume 92, Issue 5, 28 4 2019, Pages e486-e503
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A
Objective: To explore genetic and lifestyle risk factors of MRI-defined brain infarcts (BI) in large population-based cohorts. Methods: We performed meta-analyses of genome-wide association studies (GWAS) and examined associations of vascular risk factors and their genetic risk scores (GRS) with MRI-defined BI and a subset of BI, namely, small subcortical BI (SSBI), in 18 population-based cohorts (n = 20,949) from 5 ethnicities (3,726 with BI, 2,021 with SSBI). Top loci were followed up in 7 pop...
Abstract
Cited 2 times since 2019 (0.3 per year)
source: EuropePMC
Journal of plastic surgery and hand surgery,
Volume 53, Issue 3, 27 4 2019, Pages 161-166
Comparison of wound closure techniques in median sternotomy scars in children: subcuticular suture versus Steri-Strip™ S.
van de Kar AL, Koolbergen DR, van Avendonk JPH, van der Horst CMAM
Objectives: The aim of this retrospective study was to compare subcuticular sutures and Steri-Strip™ S in closing median sternotomy incisions in children with regard to wound healing and scar formation. Methods: Fifty-three children and adolescents were enrolled in this study who all underwent a median sternotomy at age 0-18 years and had their presternal cutaneous wounds closed with either a running subcuticular suture (Group 1) or Steri-Strip™ S (Group 2). Their scars were assessed using the P...
Abstract
Cited 5 times since 2019 (0.8 per year)
source: EuropePMC
Journal of clinical tuberculosis and other mycobacterial diseases,
Volume 15, 25 4 2019, Pages 100089
Abnormalities suggestive of latent tuberculosis infection on chest radiography; how specific are they?
Uzorka JW, Kroft LJM, Bakker JA, van Zwet EW, Huisman E, Prins C, van der Zwan CJ, Ottenhoff THM, Arend SM
Background: Several radiological features have been reported in association with latent tuberculosis infection (LTBI) but it has not been studied which are specific. The aim of this study was to evaluate allegedly characteristic abnormalities on chest radiography (CXR) in patients with LTBI compared to uninfected controls. Methods: From 236 patients tested with QuantiFERON-TB Gold In-Tube (QFT), the CXR was re-evaluated in a blinded fashion for fibrotic scarring, (non-)calcified nodules and pleu...
Abstract
Cited 23 times since 2019 (3.8 per year)
source: EuropePMC
European journal of human genetics : EJHG,
Volume 27, Issue 6, 24 4 2019, Pages 952-962
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
van Setten J, Verweij N, Mbarek H, Niemeijer MN, Trompet S, Arking DE, Brody JA, Gandin I, Grarup N, Hall LM, Hemerich D, Lyytikäinen LP, Mei H, Müller-Nurasyid M, Prins BP, Robino A, Smith AV, Warren HR, Asselbergs FW, Boomsma DI, Caulfield MJ, Eijgelsheim M, Ford I, Hansen T, Harris TB, Heckbert SR, Hottenga JJ, Iorio A, Kors JA, Linneberg A, MacFarlane PW, Meitinger T, Nelson CP, Raitakari OT, Silva Aldana CT, Sinagra G, Sinner M, Soliman EZ, Stoll M, Uitterlinden A, van Duijn CM, Waldenberger M, Alonso A, Gasparini P, Gudnason V, Jamshidi Y, Kääb S, Kanters JK, Lehtimäki T, Munroe PB, Peters A, Samani NJ, Sotoodehnia N, Ulivi S, Wilson JG, de Geus EJC, Jukema JW, Stricker B, van der Harst P, de Bakker PIW, Isaacs A
Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart rate (RR interval). In the current study, we meta-analyzed genome-wide association results from 30,000 mostly Dutch samples on four ECG traits: PR interval, QRS duration, QT interval, and RR interval. SNP genotype data was imputed using the Genome of the Netherlands reference panel encompas...
Abstract
Cited 9 times since 2019 (1.5 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 42, Issue 3, 22 4 2019, Pages 313-320
Atrial fibrillation history impact on catheter ablation outcome. Findings from the ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry.
Stabile G, Trines SA, Arbelo E, Dagres N, Brugada J, Kautzner J, Pokushalov E, Maggioni AP, Laroche C, Anselmino M, Beinart R, Traykov V, Blomström Lundqvist C, ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry investigators
Background: Atrial fibrillation (AF) promotes atrial remodeling that in turn promotes AF perpetuation. The aim of our study is to investigate the impact of AF history length on 1-year outcome of AF catheter ablation in a cohort of patients enrolled in the Atrial Fibrillation Ablation Registry. Methods: We described the real-life clinical epidemiology, therapeutic strategies, and the short- and mid-term outcomes of 1948 patients (71.9% with paroxysmal AF) undergoing AF ablation procedures, strati...
Abstract
The Journal of thoracic and cardiovascular surgery,
Volume 157, Issue 6, 21 3 2019, Pages e371-e377
Endocardial/epicardial versus endocardial encircling cryoablation for ventricular tachycardia: A randomized trial.
van Huls van Taxis CF, Zeppenfeld K, Klautz RJ, Wijnmaalen AP
Abstract
Cited 93 times since 2019 (15.2 per year)
source: EuropePMC
The Journal of pathology,
Volume 247, Issue 3, 16 3 2019, Pages 333-346
Inflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2.
Sánchez-Duffhues G, García de Vinuesa A, van de Pol V, Geerts ME, de Vries MR, Janson SG, van Dam H, Lindeman JH, Goumans MJ, Ten Dijke P
Endothelial-to-mesenchymal transition (EndMT) has been unveiled as a common cause for a multitude of human pathologies, including cancer and cardiovascular disease. Vascular calcification is a risk factor for ischemic vascular disorders and slowing calcification may reduce mortality in affected patients. The absence of early biomarkers hampers the identification of patients at risk. EndMT and vascular calcification are induced upon cooperation between distinct stimuli, including inflammatory cyt...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 12, Issue 8 Pt 1, 16 3 2019, Pages 1568-1571
Quantitative Evaluation of High-Risk Coronary Plaque by Coronary CTA and Subsequent Acute Coronary Events.
van Rosendael AR, Al'Aref SJ, Dwivedi A, Kim TS, Peña JM, Dunham PC, Kim YJ, Chinnaiyan K, Feuchtner G, Plank F, Berman DS, Shaw LJ, Chang HJ, Lin FY, Bax JJ, Narula J, Min JK
Abstract
Cited 40 times since 2019 (6.5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 12, Issue 10, 16 3 2019, Pages 1987-1997
Superior Risk Stratification With Coronary Computed Tomography Angiography Using a Comprehensive Atherosclerotic Risk Score.
van Rosendael AR, Shaw LJ, Xie JX, Dimitriu-Leen AC, Smit JM, Scholte AJ, van Werkhoven JM, Callister TQ, DeLago A, Berman DS, Hadamitzky M, Hausleiter J, Al-Mallah MH, Budoff MJ, Kaufmann PA, Raff G, Chinnaiyan K, Cademartiri F, Maffei E, Villines TC, Kim YJ, Feuchtner G, Lin FY, Jones EC, Pontone G, Andreini D, Marques H, Rubinshtein R, Achenbach S, Dunning A, Gomez M, Hindoyan N, Gransar H, Leipsic J, Narula J, Min JK, Bax JJ
Objectives: This study was designed to assess the prognostic value of a new comprehensive coronary computed tomography angiography (CTA) score compared with the stenosis severity component of the Coronary Artery Disease-Reporting and Data System (CAD-RADS). Background: Current risk assessment with coronary CTA is mainly focused on maximal stenosis severity. Integration of plaque extent, location, and composition in a comprehensive model may improve risk stratification. Methods: A total of 2,134...
Abstract
The Journal of thoracic and cardiovascular surgery,
Volume 157, Issue 5, 11 2 2019, Pages e249-e250
The devil is in the details, not the ring.
Tomšič A, Palmen M, Klautz RJM
Abstract
Cited 5 times since 2019 (0.8 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 42, Issue 2, 9 2 2019, Pages 208-215
Impact of left atrial box surface ratio on the recurrence after ablation for persistent atrial fibrillation.
Keçe F, Scholte AJ, de Riva M, Naruse Y, Watanabe M, Alizadeh Dehnavi R, Schalij MJ, Zeppenfeld K, Trines SA
Background: The posterior wall of the left atrium (LA) is a well-known substrate for atrial fibrillation (AF) maintenance. Isolation of the posterior wall between the pulmonary veins (box lesion) may improve ablation success. Box lesion surface area size varies depending on the individual anatomy. This retrospective study evaluates the influence of box lesion surface area as a ratio of total LA surface area (box surface ratio) on arrhythmia recurrence. Methods: Seventy consecutive patients with...
Abstract
Cited 67 times since 2019 (10.9 per year)
source: EuropePMC
Molecular psychiatry,
Volume 25, Issue 10, 7 1 2019, Pages 2392-2409
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C, Surendran P, Jiang T, Adnan SD, Afaq S, Agrawal A, Altmaier E, Antoniou AC, Asselbergs FW, Baumbach C, Bierut L, Bertelsen S, Boehnke M, Bots ML, Brazel DM, Chambers JC, Chang-Claude J, Chen C, Corley J, Chou YL, David SP, de Boer RA, de Leeuw CA, Dennis JG, Dominiczak AF, Dunning AM, Easton DF, Eaton C, Elliott P, Evangelou E, Faul JD, Foroud T, Goate A, Gong J, Grabe HJ, Haessler J, Haiman C, Hallmans G, Hammerschlag AR, Harris SE, Hattersley A, Heath A, Hsu C, Iacono WG, Kanoni S, Kapoor M, Kaprio J, Kardia SL, Karpe F, Kontto J, Kooner JS, Kooperberg C, Kuulasmaa K, Laakso M, Lai D, Langenberg C, Le N, Lettre G, Loukola A, Luan J, Madden PAF, Mangino M, Marioni RE, Marouli E, Marten J, Martin NG, McGue M, Michailidou K, Mihailov E, Moayyeri A, Moitry M, Müller-Nurasyid M, Naheed A, Nauck M, Neville MJ, Nielsen SF, North K, Perola M, Pharoah PDP, Pistis G, Polderman TJ, Posthuma D, Poulter N, Qaiser B, Rasheed A, Rein
Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking behaviour-related traits. We tested up to 235,116 single nucleotide variants (SNVs) on the exome-array for association with smoking initiation, cigarettes per day, pack-years, and smoking cessation in a fixed effects meta-analysis of up to 61 studies (up to 346,813 participants). I...
Abstract
Cited 23 times since 2019 (3.7 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 42, Issue 2, 2 1 2019, Pages 120-129
Remote monitoring of implantable cardioverter defibrillators: Patient experiences and preferences for follow-up.
Timmermans I, Meine M, Szendey I, Aring J, Romero Roldán J, van Erven L, Kahlert P, Zitron E, Mabo P, Denollet J, Versteeg H
Background: Patient satisfaction with remote patient monitoring (RPM) of implantable cardioverter defibrillators (ICDs) seems to be high, yet knowledge on long-term patient experiences is limited. The European REMOTE-CIED study explored patients' experiences with RPM, examined patient's preferences for ICD follow-up, and identified determinants of patient's preferences in the first 2 years postimplantation. Methods: European heart failure patients (N = 300; median age = 66 years [...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 2, 1 1 2019, Pages 220
Severe ostial coronary lesions 10 years after Cabrol procedure: a mixed blessing technique?
Girgis HA, Kloet RW, Lamb HJ, Montero-Cabezas JM
Abstract
Cited 6 times since 2019 (1 per year)
source: EuropePMC
Journal of Alzheimer's disease : JAD,
Volume 67, Issue 1, 1 1 2019, Pages 279-289
Spatial QRS-T Angle and Cognitive Decline in Older Subjects.
Mahinrad S, Ferguson I, Macfarlane PW, Clark EN, Stott DJ, Ford I, Mooijaart SP, Trompet S, van Heemst D, Jukema JW, Sabayan B
Background: An abnormally wide spatial QRS-T angle on an ECG is a marker of heterogeneity in electrical activity of cardiac ventricles and is linked with cardiovascular events. Growing evidence suggests that cardiac dysfunction might signal future cognitive decline. Objective: In this study, we investigated whether spatial QRS-T angle associates with future cognitive decline in older subjects at high cardiovascular risk. Methods: We included 4,172 men and women (mean age 75.2±3.3 years) free of...
Abstract
Cited 811 times since 2019 (131.3 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 3, 1 1 2019, Pages 237-269
Fourth universal definition of myocardial infarction (2018).
Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD, ESC Scientific Document Group
Abstract
Cited 17 times since 2019 (2.8 per year)
source: EuropePMC
Endocrine-related cancer,
Volume 26, Issue 1, 1 1 2019, Pages 1-12
Hotspot DAXX, PTCH2 and CYFIP2 mutations in pancreatic neuroendocrine neoplasms.
Vandamme T, Beyens M, Boons G, Schepers A, Kamp K, Biermann K, Pauwels P, De Herder WW, Hofland LJ, Peeters M, Van Camp G, Op de Beeck K
Mutations in DAXX/ATRX, MEN1 and genes involved in the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway have been implicated in pancreatic neuroendocrine neoplasms (pNENs). However, mainly mutations present in the majority of tumor cells have been identified, while proliferation-driving mutations could be present only in small fractions of the tumor. This study aims to identify high- and low-abundance mutations in pNENs using ultra-deep targeted resequencing. F...
Abstract
Cited 82 times since 2019 (13.3 per year)
source: EuropePMC
JACC. Cardiovascular interventions,
Volume 12, Issue 2, 1 1 2019, Pages 182-193
Predictors of Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement.
Yoon SH, Bleiziffer S, Latib A, Eschenbach L, Ancona M, Vincent F, Kim WK, Unbehaum A, Asami M, Dhoble A, Silaschi M, Frangieh AH, Veulemans V, Tang GHL, Kuwata S, Rampat R, Schmidt T, Patel AJ, Nicz PFG, Nombela-Franco L, Kini A, Kitamura M, Sharma R, Chakravarty T, Hildick-Smith D, Arnold M, de Brito FS, Jensen C, Jung C, Jilaihawi H, Smalling RW, Maisano F, Kasel AM, Treede H, Kempfert J, Pilgrim T, Kar S, Bapat V, Whisenant BK, Van Belle E, Delgado V, Modine T, Bax JJ, Makkar RR
Objectives: The aim of this study was to evaluate the predictors of left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR). Background: LVOT obstruction is a major concern with TMVR, but limited data exist regarding its predictors and impact on outcomes. Methods: Patients with pre-procedural multidetector row computed tomography (MDCT) undergoing TMVR for failed mitral bioprosthetic valves (valve-in-valve), annuloplasty rings (valve-in-ring), and mi...
Abstract
Cited 44 times since 2019 (7.1 per year)
source: EuropePMC
Circulation,
Volume 139, Issue 3, 1 1 2019, Pages 413-415
Outcomes Associated With Cardiogenic Shock in Takotsubo Syndrome.
Di Vece D, Citro R, Cammann VL, Kato K, Gili S, Szawan KA, Micek J, Jurisic S, Ding KJ, Bacchi B, Schwyzer M, Candreva A, Bossone E, D'Ascenzo F, Sarcon A, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuβ G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Gilyarova E, Shilova A, Gilyarov M, Horowitz J, Kozel M, Tousek P, Widimský P, Winchester DE, Ukena C, Di Mario C, Prasad A, Böhm M, Bax JJ, Lüscher TF, Ruschitzka F, Ghadri JR, Templin C
Abstract
Circulation,
Volume 139, Issue 2, 1 1 2019, Pages 286-288
European Society of Cardiology Congress 2018.
Bax JJ, Achenbach S
Abstract
