7365 results
Cited 5 times since 2021 (1.3 per year)
source: EuropePMC
Journal of patient safety,
Volume 18, Issue 4, 17 3 2021, Pages e760-e768
Measuring What Matters at Morbidity and Mortality Conferences: A Scoping Review of Effectiveness Measures.
Verhagen MJ, de Vos MS, Smaggus A, Hamming JF
Objective: Efforts to study morbidity and mortality conferences (M&MC) are hampered by the lack of rigorous instruments to assess the effectiveness of the conferences for the purpose of quality improvement and medical education. This might limit further advancement of the practice. The aim of this scoping review was to determine commonly used effectiveness measures of M&MC in the literature. Method: A scoping review was performed of quantitative, qualitative, and mixed methods studies of...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Surgical infections,
Volume 23, Issue 2, 17 3 2021, Pages 135-141
Re-Assessment in Patients with Suspected Acute Appendicitis.
Bom WJ, Scheijmans JCG, van Geloven AAW, Gans SL, Boermeester MA, Bemelman WA, van Rossem CC, SNAPSHOT Collaborators
Background: The effect of diagnosing appendicitis at re-assessment on post-operative outcomes is not clear. This study aims to compare patients diagnosed with appendicitis at initial presentation versus patients who were diagnosed at re-assessment. Patients and Methods: Data from the Dutch SNAPSHOT appendicitis collaborative was used. Patients with appendicitis who underwent appendectomy were included. Effects of diagnosis at re-assessment were compared with diagnosis at initial presentation. Pr...
Abstract
Nederlands tijdschrift voor geneeskunde,
Volume 165, 16 3 2021, Pages D6492
[Appreciative calamity investigation].
Hamming JF, den Dijker L, Steneker I
Calamity investigations often lead to recommendations that are difficult to implement and that are of little relevance, because the analysis is carried out according to a cause and effect system. The complexity of care provision requires a different method that respects the complexity of day-to-day care and is able to assess it correctly. Research according to the Safety-II philosophy clearly shows the variable interactions and dependencies present in daily work. These investigations require mor...
Abstract
Cited 4 times since 2021 (1 per year)
source: EuropePMC
JMIR cardio,
Volume 5, Issue 2, 16 3 2021, Pages e26072
Real-World Experience of mHealth Implementation in Clinical Practice (the Box): Design and Usability Study.
Biersteker T, Hilt A, van der Velde E, Schalij MJ, Treskes RW
Background: Mobile health (mHealth) is an emerging field of scientific interest worldwide. Potential benefits include increased patient engagement, improved clinical outcomes, and reduced health care costs. However, mHealth is often studied in projects or trials, and structural implantation in clinical practice is less common. Objective: The purpose of this paper is to outline the design of the Box and its implementation and use in an outpatient clinic setting. The impact on logistical outcomes...
Abstract
Cited 16 times since 2021 (4.1 per year)
source: EuropePMC
Nanoscale,
Volume 13, Issue 48, 16 3 2021, Pages 20451-20461
Controlled delivery of gold nanoparticle-coupled miRNA therapeutics <i>via</i> an injectable self-healing hydrogel.
van der Ven CFT, Tibbitt MW, Conde J, van Mil A, Hjortnaes J, Doevendans PA, Sluijter JPG, Aikawa E, Langer RS
Differential expression of microRNAs (miRNAs) plays a role in many diseases, including cancer and cardiovascular diseases. Potentially, miRNAs could be targeted with miRNA-therapeutics. Sustained delivery of these therapeutics remains challenging. This study couples miR-mimics to PEG-peptide gold nanoparticles (AuNP) and loads these AuNP-miRNAs in an injectable, shear thinning, self-assembling polymer nanoparticle (PNP) hydrogel drug delivery platform to improve delivery. Spherical AuNPs coated...
Abstract
Cited 5 times since 2021 (1.3 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 10, Issue 24, 16 3 2021, Pages e023300
Cardiovascular Effects of Autologous Bone Marrow-Derived Mesenchymal Stromal Cell Therapy With Early Tacrolimus Withdrawal in Renal Transplant Recipients: An Analysis of the Randomized TRITON Study.
Meucci MC, Reinders MEJ, Groeneweg KE, Bezstarosti S, Ajmone Marsan N, Bax JJ, De Fijter JW, Delgado V
Background After renal transplantation, there is a need of immunosuppressive regimens that effectively prevent allograft rejection while minimizing cardiovascular complications. This substudy of the TRITON trial evaluated the cardiovascular effects of autologous bone marrow-derived mesenchymal stromal cells (MSCs) in renal transplant recipients. Methods and Results Renal transplant recipients were randomized to MSC therapy, infused at weeks 6 and 7 after transplantation, with withdrawal at week...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Antioxidants (Basel, Switzerland),
Volume 10, Issue 12, 15 3 2021, Pages 2002
Association of Circulating Heme Oxygenase-1, Lipid Profile and Coronary Disease Phenotype in Patients with Chronic Coronary Syndrome.
Caselli C, De Caterina R, Ragusa R, Liga R, Gimelli A, Scholte AJHA, Clerico A, Knuuti J, Neglia D
Background: The NF-E2-related factor 2 (Nrf2)/Heme Oxygenase-1 (HO-1) pathway has an emerging role in atherosclerosis. Activated by oxidative stress, it is deemed to exert athero-protective effects. We aimed at evaluating the relationships between plasma HO-1, clinical/molecular profiles and coronary disease patterns in patients with chronic coronary syndromes (CCS). Methods: HO-1 was measured in 526 patients (60 ± 9 years, 318 males) with CCS. Coronary computed tomography angiography (CTA) and...
Abstract
Cited 3 times since 2021 (0.8 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 30, Issue 6, 15 3 2021, Pages 328-334
Sex differences in treatment strategy for coronary artery aneurysms: Insights from the international Coronary Artery Aneurysm Registry.
Arslan F, Núñez-Gil IJ, Rodríguez-Olivares R, Cerrato E, Bollati M, Nombela-Franco L, Terol B, Alfonso-Rodríguez E, Camacho Freire SJ, Villablanca PA, Amat Santos IJ, De la Torre Hernández JM, Pascual I, Liebetrau C, Alkhouli M, Fernández-Ortiz A, Coronary Artery Aneurysm Registry (CAAR) investigators
Introduction: Sex disparities exist in coronary artery disease (CAD) in terms of risk profile, clinical management and outcome. It is unclear if differences are also present in coronary aneurysms, a rare variant of CAD. Methods: Patients were selected from the international Coronary Artery Aneurysm Registry (CAAR; ClinicalTrials.gov: NCT02563626), and differences between groups were analysed according to sex. The CAAR database is a prospective multicentre registry of 1565 patients with coronary...
Abstract
Cited 18 times since 2021 (4.6 per year)
source: EuropePMC
Annals of surgery,
14 2 2021
Association of Hospital Volume with Perioperative Mortality of Endovascular Repair of Complex Aortic Aneurysms: A Nationwide Cohort Study.
Alberga AJ, von Meijenfeldt GCI, Rastogi V, de Bruin JL, Wever JJ, van Herwaarden JA, Hamming JF, Hazenberg CEVB, van Schaik J, Mees BME, van der Laan MJ, Zeebregts CJ, Schurink GWH, Verhagen HJM, Dutch Society of Vascular Surgery*, the Steering Committee of the Dutch Surgical Aneurysm Audit, the Dutch Institute for Clinical Auditing
Objective: We evaluate nationwide perioperative outcomes of complex EVAR and assess the volume-outcome association of complex EVAR. Summary of background data: Endovascular treatment with fenestrated (FEVAR) or branched (BEVAR) endografts is progressively used for excluding complex aortic aneurysms (complex AAs). It is unclear if a volume-outcome association exists in endovascular treatment of complex AAs (complex EVAR). Methods: All patients prospectively registered in the Dutch Surgical Aneury...
Abstract
Cited 10 times since 2021 (2.5 per year)
source: EuropePMC
International journal of cardiology. Heart & vasculature,
Volume 38, 13 2 2021, Pages 100926
Ascending aorta curvature and flow displacement are associated with accelerated aortic growth at long-term follow-up: A MRI study in Marfan and thoracic aortic aneurysm patients.
van Hout MJP, Juffermans JF, Lamb HJ, Kröner ESJ, van den Boogaard PJ, Schalij MJ, Dekkers IA, Scholte AJ, Westenberg JJ
Background: Aortic aneurysm formation is associated with increased risk of aortic dissection. Current diagnostic strategies are focused on diameter growth, the predictive value of aortic morphology and function remains underinvestigated. We aimed to assess the long-term prognostic value of ascending aorta (AA) curvature radius, regional pulse wave velocity (PWV) and flow displacement (FD) on aortic dilatation/elongation and evaluated adverse outcomes (proximal aortic surgery, dissection/rupture,...
Abstract
Cited 5 times since 2021 (1.3 per year)
source: EuropePMC
Trials,
Volume 22, Issue 1, 11 2 2021, Pages 902
The effectiveness of antibacterial therapeutic clothing based on silver or chitosan as compared with non-antibacterial therapeutic clothing in patients with moderate to severe atopic dermatitis (ABC trial): study protocol for a pragmatic randomized controlled trial.
Ragamin A, Fieten KB, Tupker RA, de Wit J, van Mierlo MMF, Jansen MS, Bronner MB, Schappin R, Schuren FHJ, Romeijn MLE, Arents BWM, Polinder S, de Graaf M, Rustemeyer T, Schuttelaar MLA, Pasmans SGMA
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects 10 to 20% of children and between 2 and 15% of the adults in Western Europe. Since 2000, therapeutic clothing or functional textiles based on silver or chitosan as antibacterial agents were introduced for AD. These agents aim to reduce skin colonization with Staphylococcus (S.) aureus. Increased colonization with S. aureus is correlated with increased AD severity. The antimicrobial effects of silver and chitos...
Abstract
Cited 11 times since 2021 (2.8 per year)
source: EuropePMC
Clinical epigenetics,
Volume 13, Issue 1, 11 2 2021, Pages 217
Genome-wide methylation patterns in Marfan syndrome.
van Andel MM, Groenink M, van den Berg MP, Timmermans J, Scholte AJHA, Mulder BJM, Zwinderman AH, de Waard V
Background: Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the Fibrillin-1 gene (FBN1). Here, we undertook the first epigenome-wide association study (EWAS) in patients with MFS aiming at identifying DNA methylation loci associated with MFS phenotypes that may shed light on the disease process. Methods: The Illumina 450 k DNA-methylation array was used on stored peripheral whole-blood samples of 190 patients with MFS originally included in the COMPARE trial. An unbi...
Abstract
Cited 31 times since 2021 (7.9 per year)
source: EuropePMC
Circulation research,
Volume 130, Issue 2, 10 2 2021, Pages 166-180
Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries.
Škorić-Milosavljević D, Tadros R, Bosada FM, Tessadori F, van Weerd JH, Woudstra OI, Tjong FVY, Lahrouchi N, Bajolle F, Cordell HJ, Agopian AJ, Blue GM, Barge-Schaapveld DQCM, Gewillig M, Preuss C, Lodder EM, Barnett P, Ilgun A, Beekman L, van Duijvenboden K, Bokenkamp R, Müller-Nurasyid M, KORA-Study Group, Vliegen HW, Konings TC, van Melle JP, van Dijk APJ, van Kimmenade RRJ, Roos-Hesselink JW, Sieswerda GT, Meijboom F, Abdul-Khaliq H, Berger F, Dittrich S, Hitz MP, Moosmann J, Riede FT, Schubert S, Galan P, Lathrop M, Munter HM, Al-Chalabi A, Shaw CE, Shaw PJ, Morrison KE, Veldink JH, van den Berg LH, Evans S, Nobrega MA, Aneas I, Radivojkov-Blagojević M, Meitinger T, Oechslin E, Mondal T, Bergin L, Smythe JF, Altamirano-Diaz L, Lougheed J, Bouma BJ, Chaix MA, Kline J, Bassett AS, Andelfinger G, van der Palen RLF, Bouvagnet P, Clur SB, Breckpot J, Kerstjens-Frederikse WS, Winlaw DS, Bauer UMM, Mital S, Goldmuntz E, Keavney B, Bonnet D, Mulder BJ, Tanck MWT, Bakkers J, Christoffels VM, Boogerd CJ, Postma AV
Rationale: Dextro-transposition of the great arteries (D-TGA) is a severe congenital heart defect which affects approximately 1 in 4,000 live births. While there are several reports of D-TGA patients with rare variants in individual genes, the majority of D-TGA cases remain genetically elusive. Familial recurrence patterns and the observation that most cases with D-TGA are sporadic suggest a polygenic inheritance for the disorder, yet this remains unexplored. Objective: We sought to study the ro...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 29, Issue 6, 9 2 2021, Pages 3177-3178
Myocardial sympathetic denervation in Chagas' cardiomyopathy: A predictor of deterioration of left ventricular systolic function.
van der Bijl P, Bax JJ
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 22, Issue 24, 9 2 2021, Pages 13244
Arteriogenesis and Therapeutic Angiogenesis-An Update.
Deindl E, Quax PHA
Vascular occlusive diseases such myocardial infarction, peripheral artery disease of the lower extremities, or stroke still represent a substantial health burden worldwide [...].
Abstract
Cited 688 times since 2021 (174.8 per year)
source: EuropePMC
Nature,
Volume 600, Issue 7890, 9 2 2021, Pages 675-679
The power of genetic diversity in genome-wide association studies of lipids.
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, Choudhury A, Bentley AR, Ekoru K, Verma A, Trivedi B, Martin HC, Hunt KA, Hui Q, Klarin D, Zhu X, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Ruotsalainen SE, Havulinna AS, Veturi Y, Feng Q, Rosenthal EA, Lingren T, Pacheco JA, Pendergrass SA, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Hindy G, Rasheed A, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Willemsen G, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Yao J, Manichaikul A, Warren HR, Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Sidore C, Fiorillo E, McD
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use1. Despite advances in prevention and treatment, in particular through reducing low-density lipoprotein cholesterol levels2, heart disease remains the leading cause of death worldwide3. Genome-wideassociation studies (GWAS) of blood lipid levels have led to important biological and clinical insights, as well as new drug targets,...
Abstract
Cited 3 times since 2021 (0.8 per year)
source: EuropePMC
Appetite,
Volume 170, 8 2 2021, Pages 105853
To like or not to like: Negotiating food assessments of children from families with a low socioeconomic position.
van der Heijden A, Te Molder H, Huma B, Jager G
The present study explored how primary school-aged children from families with a low socioeconomic position produce 'likes' and 'dislikes' of foods during everyday family meals, and how these (dis)likes are understood and treated by their parents. It is crucial to understand how food preferences develop in the course of everyday life, as it is known that there are socioeconomic disparities in food preference and consumption, and that children from families with a low socioeco...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Epilepsy & behavior : E&B,
Volume 126, 2 1 2021, Pages 108456
Infantile spasms: Knowledge, attitude, and practice of pediatricians in Turkey.
Yılmaz D, Yayıcı Köken Ö, Gürkaş E, Ceylan N, Çıtak Kurt AN
Background: Infantile Spasms Syndrome (ISS) encompasses both West syndrome (WS), comprising epileptic spasms, psychomotor stagnation or regression and hypsarrhythmia, and also infants presenting with epileptic spasms who do not fulfill the triad of WS. Objective: To investigate the knowledge, attitude, and practice regarding ISS among Turkish pediatricians and pediatric residents. Methods: A cross-sectional study was conducted among pediatricians and pediatric residents from all regions of Turke...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Indian heart journal,
Volume 74, Issue 1, 2 1 2021, Pages 76-78
Acute aortic syndromes in India: The need for a nationwide program to increase awareness.
Shetty V, Shetty D, Grewal N
Acute aortic dissection is a rare, but potentially life-threatening and time-critical condition that is frequently misdiagnosed. Therefore, its prompt and proper diagnosis is vital to increase a patient's chance of survival and to prevent grievous complications. Raising awareness and educating the general population and healthcare professionals about an aortic dissection is mandatory, for early diagnosis and improving the chances of survival.
Abstract
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 1, 1 1 2021, Pages 113-114
Atrial positron emission tomography in atrial fibrillation: predicting radiofrequency catheter ablation success.
van der Bijl P, van Rosendael A, Bax JJ
Abstract
