7996 results
Cited 9 times since 2018 (1.4 per year)
source: EuropePMC
Endocrine,
Volume 62, Issue 3, 20 3 2018, Pages 639-647
SSTR2A expression in medullary thyroid carcinoma is correlated with longer survival.
de Vries LH, Lodewijk L, Willems SM, Dreijerink KMA, de Keizer B, van Diest PJ, Schepers A, Bonenkamp HJ, van Engen-van Grunsven IACH, Kruijff S, van Hemel BM, Links TP, Nieveen van Dijkum EJM, van Eeden S, Valk GD, Borel Rinkes IHM, Vriens MR
Purpose: Medullary thyroid carcinoma (MTC) derives from the parafollicular C-cells of the thyroid gland. Somatostatin receptors (SSTRs) are expressed in various neuroendocrine tumours including MTC. The aim of this study was to evaluate SSTR2A as a prognostic factor for MTC, to study distribution of SSTR2A expression within tumours and to compare expression of SSTR2A between primary tumours and corresponding lymph node metastases. Methods: Patients who underwent surgery between 1988 and 2014 for...
Abstract
Cited 3 times since 2018 (0.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 122, Issue 10, 20 3 2018, Pages 1591-1597
Effect of Guideline-Based Therapy on Left Ventricular Systolic Function Recovery After ST-Segment Elevation Myocardial Infarction.
Abou R, Leung M, Goedemans L, Hoogslag GE, Schalij MJ, Marsan NA, Bax JJ, Delgado V
Little is known about the proportion of ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention, who have reduced left ventricular ejection fraction (LVEF) within 48 hours (baseline) of admission and exhibit LVEF recovery under optimal guideline-based medical treatment. Therefore, the present study evaluates the evolution of LVEF in patients after STEMI and under guideline-based medical therapy. In 2,853 STEMI patients treated with prim...
Abstract
Cited 20 times since 2018 (3 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 156, Issue 6, 18 3 2018, Pages 2260-2269
Coding of coronary arterial origin and branching in congenital heart disease: The modified Leiden Convention.
Gittenberger-de Groot AC, Koenraadt WMC, Bartelings MM, Bökenkamp R, DeRuiter MC, Hazekamp MG, Bogers AJJC, Quaegebeur JM, Schalij MJ, Vliegen HW, Poelmann RE, Jongbloed MRM
Objectives: Variations in coronary anatomy are common and may relate to the position of the coronary ostium relative to the aortic sinus, the angle of coronary take-off, or the course of the coronary arterial branches. Several classification systems have been proposed. However, they all lack a simple rationale that is applicable irrespective of the relative position of the great arteries, as well as in bicuspid aortic valves. We present a modification of a relatively simple system introduced in...
Abstract
Accident; analysis and prevention,
Volume 125, 18 3 2018, Pages 336-343
Forecasting German crash numbers: The effect of meteorological variables.
Diependaele K, Martensen H, Lerner M, Schepers A, Bijleveld F, Commandeur JJF
At the end of each year, the German Federal Highway Research Institute (BASt) publishes the road safety balance of the closing year. They describe the development of accident and casualty numbers disaggregated by road user types, age groups, type of road and the consequences of the accidents. However, at the time of publishing, these series are only available for the first eight or nine months of the year. To make the balance for the whole year, the last three or four months are forecasted. The...
Abstract
Cited 1 times since 2018 (0.2 per year)
source: EuropePMC
Medical science educator,
Volume 28, Issue 4, 17 3 2018, Pages 639-647
Resident and Faculty Attitudes Toward the Dutch Radiology Progress Test as It Transitions from a Formative to a Summative Measure of Licensure Eligibility.
Rutgers DR, van Schaik JPJ, van Lankeren W, van Raamt F, Cate TJT
Background: Progress testing, a regularly administered comprehensive test of a complete knowledge domain, usually serves to provide learners feedback and has a formative nature. Objective: Our study aimed to investigate the acceptability of introducing a summative component in the postgraduate Dutch Radiology Progress Test (DRPT) among residents and program directors in a competency-based training program. Methods: A 15-item questionnaire with 3 items on acceptability of summative postgraduate k...
Abstract
Cited 1 times since 2018 (0.2 per year)
source: EuropePMC
Cells, tissues, organs,
Volume 205, Issue 4, 17 3 2018, Pages 208-216
The Effects of Hypericum perforatum L. on the Proliferation, Osteogenic Differentiation, and Inflammatory Response of Mesenchymal Stem Cells from Different Niches.
Mendi A, Gökçınar Yağcı B, Saraç N, Kızıloğlu M, Uğur A, Uçkan D, Yılmaz D
The aim of this study is to demonstrate and compare the differentiation, proliferation, migration and inflammatory behavior of dental pulp- and bone marrow-derived mesenchymal stem cells (DP-MSCs and BM-MSCs) in response to a Hypericum perforatum ethanol extract. Using xCELLigence, a real-time monitoring system, a dose of 10 µg/mL was found to be the most efficient concentration for vitality. The IC50 values and doubling time were calculated. The results showed that H. perforatum L. was able to...
Abstract
Cited 11 times since 2018 (1.7 per year)
source: EuropePMC
American heart journal,
Volume 205, 16 3 2018, Pages 70-76
Mortality differences in acute myocardial infarction patients in the Netherlands: The weekend-effect.
Eindhoven DC, Wu HW, Kremer SWF, van Erkelens JA, Cannegieter SC, Schalij MJ, Borleffs CJW
Objective: Several studies have shown that patients admitted with an acute myocardial infarction during the weekends have a higher mortality rate than those admitted during weekdays, possibly attributable to less trained personnel available and a lower use of medical procedures. The current study aimed to assess this ‘weekend-effect’ in a nationwide registry. Methods: In the Netherlands, all inhabitants are, by law, obliged to have health insurance and all claim data are centrally registered. In...
Abstract
JACC. Cardiovascular interventions,
Volume 11, Issue 17, 15 3 2018, Pages e141-e142
Difficult Vascular Access in Urgent Coronary Artery Angiogram: A Rare Case of a Persistent Sciatic Artery.
van Rees JB, Montero-Cabezas JM, Ghariq E, Schalij MJ
Abstract
Cited 48 times since 2018 (7.3 per year)
source: EuropePMC
Circulation,
Volume 138, Issue 22, 15 3 2018, Pages 2499-2512
Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment.
Sliz E, Kettunen J, Holmes MV, Williams CO, Boachie C, Wang Q, Männikkö M, Sebert S, Walters R, Lin K, Millwood IY, Clarke R, Li L, Rankin N, Welsh P, Delles C, Jukema JW, Trompet S, Ford I, Perola M, Salomaa V, Järvelin MR, Chen Z, Lawlor DA, Ala-Korpela M, Danesh J, Davey Smith G, Sattar N, Butterworth A, Würtz P
Background: Both statins and PCSK9 inhibitors lower blood low-density lipoprotein cholesterol (LDL-C) levels to reduce risk of cardiovascular events. To assess potential differences between metabolic effects of these two lipid-lowering therapies, we performed detailed lipid and metabolite profiling of a large randomized statin trial and compared the results with the effects of genetic inhibition of PCSK9, acting as a naturally occurring trial. Methods: 228 circulating metabolic measures were qua...
Abstract
Cited 19 times since 2018 (2.9 per year)
source: EuropePMC
World journal of urology,
Volume 37, Issue 1, 14 2 2018, Pages 51-60
ICUD-SIU International Consultation on Bladder Cancer 2017: management of non-muscle invasive bladder cancer.
Monteiro LL, Witjes JA, Agarwal PK, Anderson CB, Bivalacqua TJ, Bochner BH, Boormans JL, Chang SS, Domínguez-Escrig JL, McKiernan JM, Dinney C, Godoy G, Kulkarni GS, Mariappan P, O'Donnell MA, Rentsch CA, Shah JB, Solsona E, Svatek RS, van der Heijden AG, van Valenberg FJP, Kassouf W
Purpose: To provide a summary of the Third International Consultation on Bladder Cancer recommendations for the management of non-muscle invasive bladder cancer (NMIBC). Methods: A detailed review of the literature was performed focusing on original articles for the management of NMIBC. An international committee assessed and graded the articles based on the Oxford Centre for Evidence-based Medicine system. The entire spectrum of NMIBC was covered such as prognostic factors of recurrence and pro...
Abstract
Cited 25 times since 2018 (3.8 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 56, Issue 5, 14 2 2018, Pages 663-671
High Density of Periaortic Adipose Tissue in Abdominal Aortic Aneurysm.
Dias-Neto M, Meekel JP, van Schaik TG, Hoozemans J, Sousa-Nunes F, Henriques-Coelho T, Lely RJ, Wisselink W, Blankensteijn JD, Yeung KK
Objectives: Perivascular adipose tissue (PVAT) is currently seen as a paracrine organ that produces vasoactive substances, including inflammatory agents, which may have an impact on the vasculature. In this study PVAT density was quantified in patients with an aortic aneurysm and compared with those with a non-dilated aorta. Since chronic inflammation, as the pathway to medial thinning, is a hallmark of abdominal aortic aneurysms (AAAs), it was hypothesised that PVAT density is higher in AAA pat...
Abstract
Cited 11 times since 2018 (1.7 per year)
source: EuropePMC
Journal of evolutionary biology,
Volume 31, Issue 10, 14 2 2018, Pages 1582-1588
Hibernation constrains brain size evolution in mammals.
Heldstab SA, Isler K, van Schaik CP
The expensive brain hypothesis predicts that the lowest stable level of steady energy input acts as a strong constraint on a species' brain size, and thus, that periodic troughs in net energy intake should select for reduced brain size relative to body mass. Here, we test this prediction for the extreme case of hibernation. Hibernators drastically reduce food intake for up to several months and are therefore expected to have smaller relative brain sizes than nonhibernating species. Using a...
Abstract
Cited 4 times since 2018 (0.6 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 106, Issue 5, 14 2 2018, Pages 1371-1378
Vasoplegia After Surgical Left Ventricular Restoration: 2-Year Follow-Up.
van Vessem ME, Palmen M, Couperus LE, Stijnen T, Berendsen RR, Aarts LPHJ, de Jonge E, Klautz RJM, Schalij MJ, Beeres SLMA
Background: Vasoplegia is a severe complication that can develop after surgical procedures for heart failure. The current study evaluated the effect of vasoplegia on survival, cardiac function, and renal function 2 years after surgical left ventricular restoration (SVR). Methods: Heart failure patients with a left ventricular ejection fraction (LVEF) of 0.35 or less who underwent SVR in 2006 to 2014 were included. Vasoplegia was defined as the continuous need of vasopressors (norepinephrine ≥0.2...
Abstract
Cited 2 times since 2018 (0.3 per year)
source: EuropePMC
Frontiers in psychiatry,
Volume 9, 7 1 2018, Pages 349
No Effect of Dose Adjustment to the <i>CYP2D6</i> Genotype in Patients With Severe Mental Illness.
Koopmans AB, Vinkers DJ, Poulina IT, Gelan PJA, van Schaik RHN, Hoek HW, van Harten PN
Background: The CYP2D6 enzyme is involved in the metabolism of numerous psychopharmacological drugs. Guidelines recommend how to adjust the dose of medication based on the CYP2D6 genotype. Aims: To evaluate the effect of dose adjustment to the CYP2D6 genotype and phenotype, in patients with severe mental illness (SMI) already receiving psychopharmacological treatment. Methods: A total of 269 psychiatric patients (on the island Curaçao) receiving antipsychotic treatment were genotyped for CYP2D6....
Abstract
Cited 2 times since 2018 (0.3 per year)
source: EuropePMC
European heart journal. Case reports,
Volume 2, Issue 3, 2 1 2018, Pages yty090
Rupture of a giant aneurysm of the sinus of Valsalva leading to acute heart failure: a case report demonstrating the excellence of echocardiography.
Wierda E, Koolbergen DR, de Mol BAJM, Bouma BJ
Abstract
Cited 51 times since 2018 (7.7 per year)
source: EuropePMC
Peptides,
Volume 107, 1 1 2018, Pages 25-31
Sex differences in body fat distribution are related to sex differences in serum leptin and adiponectin.
Christen T, Trompet S, Noordam R, van Klinken JB, van Dijk KW, Lamb HJ, Cobbaert CM, den Heijer M, Jazet IM, Jukema JW, Rosendaal FR, de Mutsert R
It is debated whether sex differences in adiponectin and leptin are due to sex differences in body fat distribution. In this cross-sectional analysis of the Netherlands Epidemiology of Obesity study, associations of measures of body fat and sex with serum adiponectin and leptin concentrations were examined using linear regression analysis (n = 6494, VAT: n = 2516). Sex differences were additionally adjusted for the measure of body fat that was most strongly associated with adiponectin or leptin...
Abstract
Cited 22 times since 2018 (3.3 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 31, Issue 8, 1 1 2018, Pages 916-925
Impact of Diabetes and Increasing Body Mass Index Category on Left Ventricular Systolic and Diastolic Function.
Ng ACT, Prevedello F, Dolci G, Roos CJ, Djaberi R, Bertini M, Ewe SH, Allman C, Leung DY, Marsan NA, Delgado V, Bax JJ
Background: Diabetes and obesity are both worldwide growing epidemics, and both are independently associated with increased risk for heart failure and death. The aim of this study was to examine the additive detrimental effect of both diabetes and increasing body mass index (BMI) category on left ventricular (LV) myocardial systolic and diastolic function. Methods: The present retrospective multicenter study included 653 patients (337 with type 2 diabetes and 316 without diabetes) of increasing...
Abstract
Cited 6 times since 2018 (0.9 per year)
source: EuropePMC
Arrhythmia & electrophysiology review,
Volume 7, Issue 3, 1 1 2018, Pages 169-180
The Impact of Advances in Atrial Fibrillation Ablation Devices on the Incidence and Prevention of Complications.
Keçe F, Zeppenfeld K, Trines SA
The number of patients with atrial fibrillation currently referred for catheter ablation is increasing. However, the number of trained operators and the capacity of many electrophysiology labs are limited. Accordingly, a steeper learning curve and technical advances for efficient and safe ablation are desirable. During the last decades several catheter-based ablation devices have been developed and adapted to improve not only lesion durability, but also safety profiles, to shorten procedure time...
Abstract
Cited 1 times since 2018 (0.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 25, Issue 4, 1 1 2018, Pages 1237-1241
Correction to: Radiopharmaceutical tracers for cardiac imaging.
Manabe O, Kikuchi T, Scholte AJHA, El Mahdiui M, Nishii R, Zhang MR, Suzuki E, Yoshinaga K
Regrettably the original version of the above article contained errors in the three chemical structures presented in the 'Atherosclerosis imaging' section of Table 5, namely: 99mTc annexin V, 68Ga DOTATATE, and 64Cu DOTATATE; the chemical structures have been corrected in Table presented here. In addition, the radiopharmaceutical for isotope 67Ga has been corrected to 67Ga citrate, and many of the radiopharmaceuticals presented at the end of the table have been corrected.
Abstract
Cited 66 times since 2018 (10 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 11, Issue 8, 1 1 2018, Pages e007372
Impact of Epicardial Adipose Tissue, Left Ventricular Myocardial Fat Content, and Interstitial Fibrosis on Myocardial Contractile Function.
Ng ACT, Strudwick M, van der Geest RJ, Ng ACC, Gillinder L, Goo SY, Cowin G, Delgado V, Wang WYS, Bax JJ
Background Current understanding of metabolic heart disease consists of a myriad of different pathophysiological mechanisms. Epicardial adipose tissue (EAT) is increasingly recognized as metabolically active and associated with adverse cardiovascular outcomes. The present study aimed to investigate the effect of increased EAT volume index on left ventricular (LV) myocardial fat content and burden of interstitial myocardial fibrosis and their subsequent effects on LV myocardial contractile functi...
Abstract
