Research

Publications

Below you can find a list of our published research.

7154 results

Cited 14 times since 2013 (1.2 per year) source: EuropePMC

Journal of electrocardiology, Volume 47, Issue 2, 27 4 2013, Pages 183-190 Acute coronary syndrome with a totally occluded culprit artery: relation of the ST injury vector with ST-elevation and non-ST elevation ECGs. Man S, Rahmattulla C, Maan AC, van der Putten NH, Dijk WA, van Zwet EW, van der Wall EE, Schalij MJ, Gorgels AP, Swenne CA

Background: In acute coronary syndrome (ACS), ST-segment elevation (STE), often associated with a completely occluded culprit artery, is an important ECG criterion for primary percutaneous coronary intervention (PCI). However, several studies showed that in ACS a completely occluded culprit artery can also occur with a non-ST-elevation (NSTE) ECG. In order to elucidate reasons for this discrepancy we examined ST injury vector orientation and magnitude in ACS patients with and without STE, all ad... Abstract

Cited 19 times since 2013 (1.7 per year) source: EuropePMC

Thyroid : official journal of the American Thyroid Association, Volume 24, Issue 2, 13 2 2013, Pages 208-214 Subclinical thyroid dysfunction and functional capacity among elderly. Virgini VS, Wijsman LW, Rodondi N, Bauer DC, Kearney PM, Gussekloo J, den Elzen WP, Jukema JW, Westendorp RG, Ford I, Stott DJ, Mooijaart SP, PROSPER Study Group

Background: Subclinical thyroid dysfunction is common among older people and has been associated with decreased functional capacity but with conflicting data. The aim of this study was to assess the association between subclinical thyroid dysfunction and functional capacity in an elderly population. Methods: We included 5182 participants with a mean age of 75.2 years from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Self-reported functional capacity was assessed using t... Abstract

Cited 85 times since 2013 (7.5 per year) source: EuropePMC

The lancet. Diabetes & endocrinology, Volume 2, Issue 3, 12 2 2013, Pages 210-217 Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study. Bakker LE, Boon MR, van der Linden RA, Arias-Bouda LP, van Klinken JB, Smit F, Verberne HJ, Jukema JW, Tamsma JT, Havekes LM, van Marken Lichtenbelt WD, Jazet IM, Rensen PC

Background: Individuals of south Asian origin have a very high risk of developing type 2 diabetes compared with white Caucasians. We aimed to assess volume and activity of brown adipose tissue (BAT), which is thought to have a role in energy metabolism by combusting fatty acids and glucose to produce heat and might contribute to the difference in incidence of type 2 diabetes between ethnic groups. Methods: We enrolled Dutch nationals with south Asian ancestry and matched Caucasian participants a... Abstract

Cited 39 times since 2013 (3.4 per year) source: EuropePMC

Psychological research, Volume 78, Issue 6, 8 2 2013, Pages 878-891 Optimal training design for procedural motor skills: a review and application to laparoscopic surgery. Spruit EN, Band GP, Hamming JF, Ridderinkhof KR

This literature review covers the choices to consider in training complex procedural, perceptual and motor skills. In particular, we focus on laparoscopic surgery. An overview is provided of important training factors modulating the acquisition, durability, transfer, and efficiency of trained skills. We summarize empirical studies and their theoretical background on the topic of training complex cognitive and motor skills that are pertinent to proficiency in laparoscopic surgery. The overview pe... Abstract

Cited 9 times since 2013 (0.8 per year) source: EuropePMC

American heart journal, Volume 167, Issue 2, 6 1 2013, Pages 178-185 Erectile dysfunction in the cardiology practice-a patients' perspective. Nicolai MP, van Bavel J, Somsen GA, de Grooth GJ, Tulevski II, Lorsheyd A, Putter H, Schalij MJ, Pelger RC, Elzevier HW

Background: Erectile dysfunction (ED) is an independent risk factor for cardiovascular events sharing mutual risk factors with coronary artery disease. Several guidelines for the management of ED in cardiovascular disease have been proposed, recommending cardiologists to routinely inquire about erectile function. However, males' specific needs and wishes regarding sexual health care in cardiology are unknown. We sought to identify male patients' view concerning possible improvements in... Abstract

Cited 31 times since 2013 (2.7 per year) source: EuropePMC

Annals of surgery, Volume 258, Issue 5, 1 1 2013, Pages 743-51; discussion 752-3 The 14q32 microRNA-487b targets the antiapoptotic insulin receptor substrate 1 in hypertension-induced remodeling of the aorta. Nossent AY, Eskildsen TV, Andersen LB, Bie P, Brønnum H, Schneider M, Andersen DC, Welten SM, Jeppesen PL, Hamming JF, Hansen JL, Quax PH, Sheikh SP

Objectives: To study the role of microRNAs in hypertension-induced vascular pathology before the onset of symptoms of severe cardiovascular disease. Background: MicroRNAs play a crucial role in cardiovascular disease. However, microRNAs are often studied in full-blown cardiovascular disease models, not during development of cardiovascular pathology. Methods: Angiotensin II was infused into healthy adult rats, inducing chronic hypertension, and microRNA expression profiles were obtained. The most... Abstract

Cited 36 times since 2013 (3.2 per year) source: EuropePMC

Circulation. Cardiovascular imaging, Volume 7, Issue 1, 1 1 2013, Pages 74-81 Association between left ventricular global longitudinal strain and adverse left ventricular dilatation after ST-segment-elevation myocardial infarction. Joyce E, Hoogslag GE, Leong DP, Debonnaire P, Katsanos S, Boden H, Schalij MJ, Marsan NA, Bax JJ, Delgado V

Background: Myocardial infarct size is a major determinant of left ventricular (LV) remodeling after ST-segment-elevation myocardial infarction. We evaluated whether LV global longitudinal strain (GLS), proposed as a novel marker of infarct size, is associated with 3- and 6-month LV dilatation after ST-segment-elevation myocardial infarction. Methods and results: In the first ST-segment-elevation myocardial infarction patients treated with primary percutaneous coronary intervention, baseline LVG... Abstract

Cited 14 times since 2013 (1.2 per year) source: EuropePMC

Journal of electrocardiology, Volume 47, Issue 2, 1 1 2013, Pages 175-182 Electrocardiographic detection of right ventricular pressure overload in patients with suspected pulmonary hypertension. Kamphuis VP, Haeck ML, Wagner GS, Maan AC, Maynard C, Delgado V, Vliegen HW, Swenne CA

Background and purpose: Early, preferably noninvasive, detection of pulmonary hypertension improves prognosis. Our study evaluated the diagnostic accuracy of the electrocardiographically derived Butler-Leggett (BL) score and ventricular gradient (VG) to estimate mean pulmonary artery pressure (PAP). Methods: In 63 patients with suspected pulmonary hypertension, BL score and VG were calculated. The VG was projected on a direction optimized for detection of right ventricular pressure overload (VG-... Abstract

Cited 12 times since 2013 (1.1 per year) source: EuropePMC

European journal of anaesthesiology, Volume 30, Issue 11, 1 1 2013, Pages 685-694 Minimised closed circuit coronary artery bypass grafting in the elderly is associated with lower levels of organ-specific biomarkers: a prospective randomised study. van Boven WJ, Gerritsen WB, Driessen AH, van Dongen EP, Klautz RJ, Aarts LP

Background: Restrictive fluid management may protect organ function and improve postoperative outcome in elderly coronary artery bypass grafting (CABG) patients. Objective: We assessed organ-specific biomarker release to study the contribution of a fluid restrictive closed circuit concept to organ protection in elderly CABG patients. Cardiac, respiratory and abdominal organ injury was measured during and following minimal fluid coronary artery bypass grafting (mCABG), off-pump coronary artery by... Abstract

Cited 5 times since 2013 (0.4 per year) source: EuropePMC

Circulation. Cardiovascular imaging, Volume 6, Issue 6, 1 1 2013, Pages 855-857 Papillary muscle infarction, mitral regurgitation, and long-term prognosis. Bax JJ, Delgado V

Abstract

Cited 7 times since 2013 (0.6 per year) source: EuropePMC

Acta orthopaedica, Volume 84, Issue 5, 31 5 2013, Pages 489-494 Conversion to below-elbow cast after 3 weeks is safe for diaphyseal both-bone forearm fractures in children. Colaris JW, Allema JH, Biter LU, Reijman M, van de Ven CP, de Vries MR, Bloem RM, Kerver AJ, Verhaar JA

Background: It is unclear whether it is safe to convert above-elbow cast (AEC) to below-elbow cast (BEC) in a child who has sustained a displaced diaphyseal both-bone forearm fracture that is stable after reduction. In this multicenter study, we wanted to answer the question: does early conversion to BEC cause similar forearm rotation to that after treatment with AEC alone? Children and methods: Children were randomly allocated to 6 weeks of AEC, or 3 weeks of AEC followed by 3 weeks of BEC. The... Abstract

Cited 17 times since 2013 (1.5 per year) source: EuropePMC

Neurology, Volume 81, Issue 22, 30 5 2013, Pages 1922-1929 Total cerebral blood flow and mortality in old age: a 12-year follow-up study. Sabayan B, van der Grond J, Westendorp RG, Jukema JW, Ford I, Buckley BM, Sattar N, van Osch MJ, van Buchem MA, de Craen AJ

Objective: To examine the association of total cerebral blood flow (CBF) with all-cause, noncardiovascular, and cardiovascular mortality in older subjects at risk of cardiovascular disease. Methods: We included 411 subjects with a mean age of 74.5 years from the MRI substudy of the Prospective Study of Pravastatin in the Elderly at Risk. Total CBF was measured at baseline, and occurrence of death was recorded in an average follow-up period of 11.8 years. For each participant, total CBF was stand... Abstract

Cited 1 times since 2013 (0.1 per year) source: EuropePMC

Journal of plastic, reconstructive & aesthetic surgery : JPRAS, Volume 67, Issue 3, 27 4 2013, Pages 411-412 Response from the authors of 'Treatment of infantile haemangiomas with atenolol: comparison with a historical propranolol group'. de Graaf M, Raphael MF, Breugem CC, Knol MJ, Bruijnzeel-Koomen CA, Kon M, Breur JM, Pasmans SG

Abstract

Cited 1 times since 2013 (0.1 per year) source: EuropePMC

Heart rhythm, Volume 11, Issue 8, 22 4 2013, Pages 1490-1491 Cardiac sympathetic innervation in a patient with catecholaminergic polymorphic ventricular tachycardia. Paul M, Kies P, Schäfers M, Schulze-Bahr E

Abstract

Cited 18 times since 2013 (1.6 per year) source: EuropePMC

International journal of cardiology, Volume 169, Issue 6, 11 2 2013, Pages 439-444 5-year serial follow-up of clinical condition and ventricular function in patients after repair of tetralogy of Fallot. Luijnenburg SE, Helbing WA, Moelker A, Kroft LJ, Groenink M, Roos-Hesselink JW, de Rijke YB, Hazekamp MG, Bogers AJ, Vliegen HW, Mulder BJ

Objective: To study the changes over time in biventricular size and function, and clinical parameters in patients after repair of tetralogy of Fallot (TOF) without subsequent pulmonary valve replacement (PVR). Methods: We prospectively included 78 non-PVR patients (age 20(6-60)years at baseline), who were studied twice with a 5-year interval. Patients underwent magnetic resonance imaging for assessment of biventricular size and function. Exercise testing and electrocardiography were performed to... Abstract

Cited 13 times since 2013 (1.1 per year) source: EuropePMC

Atherosclerosis, Volume 231, Issue 2, 10 2 2013, Pages 346-351 Increased cytokine response after toll-like receptor stimulation in patients with stable coronary artery disease. Elsenberg EH, Sels JE, Hillaert MA, Schoneveld AH, van den Dungen NA, van Holten TC, Roest M, Jukema JW, van Zonneveld AJ, de Groot PG, Pijls N, Pasterkamp G, Hoefer IE

Objective: Atherosclerosis is associated with increased levels of plasma cytokines and expression of Toll-like receptors (TLRs). Yet, little is known about the potential use of TLR ligand induced cytokine release as a biomarker of coronary artery disease (CAD). In this study, we investigated whether TLR ligand induced cytokine release is associated with atherosclerotic disease severity and its predictive value for future cardiovascular events. Methods: Blood samples were obtained from 260 patien... Abstract

Cited 15 times since 2013 (1.3 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 33, Issue 12, 10 2 2013, Pages 2810-2817 An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation. Karper JC, de Jager SC, Ewing MM, de Vries MR, Bot I, van Santbrink PJ, Redeker A, Mallat Z, Binder CJ, Arens R, Jukema JW, Kuiper J, Quax PH

Objective: In atherosclerosis, Toll-like receptors (TLRs) are traditionally linked to effects on tissue macrophages or foam cells. RP105, a structural TLR4 homolog, is an important regulator of TLR signaling. The effects of RP105 on TLR signaling vary for different leukocyte subsets known to be involved in atherosclerosis, making it unique in its role of either suppressing (in myeloid cells) or enhancing (in B cells) TLR-regulated inflammation in different cell types. We aimed to identify a role... Abstract

Cited 12 times since 2013 (1.1 per year) source: EuropePMC

Journal of sex & marital therapy, Volume 40, Issue 4, 8 2 2013, Pages 309-322 Quality of sexual life and its effect on marital adjustment of Turkish women in pregnancy. Kisa S, Zeyneloğlu S, Yilmaz D, Güner T

Pregnancy is an important period of a woman's life that can affect marital relationships because of decrease in the sexual function. This study aimed to examine the effect of sexual life on the marital adjustment of 607 healthy, pregnant women using the self-administered Sexual Quality of Life Questionnaire-Female and the Marital Adjustment Scale. Results showed that 30% of the pregnant women experienced problems during sexual intercourse and 50% had painful intercourse. The median total sc... Abstract

Cited 37 times since 2013 (3.2 per year) source: EuropePMC

Head & neck, Volume 36, Issue 6, 4 1 2013, Pages 853-858 Intraoperative near-infrared fluorescence imaging of parathyroid adenomas with use of low-dose methylene blue. van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Tummers QR, Hutteman M, Hamming JF, Kievit J, Frangioni JV, van de Velde CJ, Vahrmeijer AL

Background: Intraoperative identification of parathyroid adenomas can be challenging. We hypothesized that low-doses methylene blue (MB) and near-infrared fluorescence (NIRF) imaging could be used to identify parathyroid adenomas intraoperatively. Methods: MB was injected intravenously after exploration at a dose of 0.5 mg/kg into 12 patients who underwent parathyroid surgery. NIRF imaging was performed using the Mini-FLARE imaging system. Results: In 10 of 12 patients, histology confirmed a par... Abstract

Cited 10 times since 2013 (0.9 per year) source: EuropePMC

Injury, Volume 45, Issue 4, 3 1 2013, Pages 696-700 Which factors affect limitation of pronation/supination after forearm fractures in children? A prospective multicentre study. Colaris JW, Allema JH, Reijman M, de Vries MR, Ulas Biter L, Bloem RM, van de Ven CP, Verhaar JA

Introduction: Both-bone forearm fractures in children frequently result in a limitation of pronation/supination, which hinders daily activities. The purpose of this prospective multicentre study was to investigate which clinical factors are related to the limitation of pronation/supination in children with a both-bone forearm fracture. Methods: In four Dutch hospitals, consecutive children ( Abstract