Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
8684 results
Cited 6 times since 2015 (0.6 per year) source: EuropePMC
Frontiers in neuroscience, Volume 9, 2 1 2015, Pages 309 Sound stream segregation: a neuromorphic approach to solve the "cocktail party problem" in real-time. Thakur CS, Wang RM, Afshar S, Hamilton TJ, Tapson JC, Shamma SA, van Schaik A
The human auditory system has the ability to segregate complex auditory scenes into a foreground component and a background, allowing us to listen to specific speech sounds from a mixture of sounds. Selective attention plays a crucial role in this process, colloquially known as the "cocktail party effect." It has not been possible to build a machine that can emulate this human ability in real-time. Here, we have developed a framework for the implementation of a neuromorphic sound segre... Abstract
Cited 18 times since 2015 (1.8 per year) source: EuropePMC
PloS one, Volume 10, Issue 9, 2 1 2015, Pages e0137035 Circulating MicroRNAs Characterizing Patients with Insufficient Coronary Collateral Artery Function. Hakimzadeh N, Nossent AY, van der Laan AM, Schirmer SH, de Ronde MW, Pinto-Sietsma SJ, van Royen N, Quax PH, Hoefer IE, Piek JJ
Background: Coronary collateral arteries function as natural bypasses in the event of coronary obstruction. The degree of collateral network development significantly impacts the outcome of patients after an acute myocardial infarction (AMI). MicroRNAs (miRNAs, miRs) have arisen as biomarkers to identify heterogeneous patients, as well as new therapeutic targets in cardiovascular disease. We sought to identify miRNAs that are differentially expressed in chronic total occlusion (CTO) patients wit... Abstract
Cited 8 times since 2015 (0.8 per year) source: EuropePMC
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Volume 26, Issue 6, 1 1 2015, Pages 613-620 Fibrinogen reduction and coagulation in cardiac surgery: an investigational study. Gielen CL, Grimbergen J, Klautz RJ, Koopman J, Quax PH
Fibrinogen as precursor of fibrin plays an essential role in clot formation. There are three main mechanisms associated with a reduction in fibrinogen concentration during cardiac surgery: hemodilution, consumption, and degradation. Moreover, early fibrinogen degradation products (FgDPs) can interfere with normal fibrin formation of intact fibrinogen. The aim of this study was to determine the relative contributions of hemodilution, consumption, and degradation to fibrinogen loss in cardiac surg... Abstract
Cited 11 times since 2015 (1.1 per year) source: EuropePMC
Journal of orthopaedic trauma, Volume 29, Issue 9, 1 1 2015, Pages e285-92 Implant Removal After Internal Fixation of a Femoral Neck Fracture: Effects on Physical Functioning. Zielinski SM, Heetveld MJ, Bhandari M, Patka P, Van Lieshout EM, FAITH Trial Investigators
Objectives: The effect of implant removal after internal fixation of a femoral neck fracture on physical functioning was analyzed. Characteristics of patients who had their implant removed were studied, as it is currently unknown from which type of patients implants are removed and what effect removal has on function. Design: Secondary cohort study alongside a randomized controlled trial. Setting: Multicenter study in 14 hospitals. Patients and intervention: Patients who had their implant remove... Abstract
Cited 9 times since 2015 (0.9 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 11 Suppl W, 1 1 2015, Pages W123-7 The tricuspid valve and the right heart: anatomical, pathological and imaging specifications. van Rosendael PJ, Delgado V, Bax JJ
Transcatheter tricuspid valve repair/replacement is an emerging therapy for patients with symptomatic severe tricuspid regurgitation who are deemed inoperable. Accurate knowledge of the anatomy of the tricuspid valve and right ventricle is key to developing transcatheter techniques. In addition, it is important to understand the mechanistic concept of transcatheter tricuspid valve repair/replacement in order to select the patients who may benefit from it. The severity and mechanism of tricuspid... Abstract
Cited 26 times since 2015 (2.7 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 20, Issue 3, 1 1 2015, Pages 289-295 Impairment measures versus inflammatory RODS in GBS and CIDP: a responsiveness comparison. Vanhoutte EK, Draak TH, Gorson KC, van Nes SI, Hoeijmakers JG, Van der Pol WL, Notermans NC, Lewis RA, Nobile-Orazio E, Léger JM, Van den Bergh PY, Lauria G, Bril V, Katzberg H, Lunn MP, Pouget J, van der Kooi AJ, Hahn AF, van Doorn PA, Cornblath DR, van den Berg LH, Faber CG, Merkies IS, PeriNomS Study Group
This study aimed to 'define responder' through the concept of minimum clinically important differences using the individually obtained standard errors (MCID-SE) and a heuristic 'external criterion' responsiveness method in patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). One hundred and fourteen newly diagnosed or relapsing patients (GBS: 55, CIDP: 59) were serially examined (1-year follow-up). The inflammatory... Abstract
Cited 6 times since 2015 (0.6 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 20, Issue 3, 1 1 2015, Pages 306-318 Outcome measures in MMN revisited: further improvement needed. Pruppers MH, Draak TH, Vanhoutte EK, Van der Pol WL, Gorson KC, Léger JM, Nobile-Orazio E, Lewis RA, van den Berg LH, Faber CG, Merkies IS, PeriNomS study group
The objectives of this study were to provide an overview of the outcome measures (OMs) applied in clinical trials in multifocal motor neuropathy (MMN) and to determine the responsiveness of a core set of selected OMs as part of the peripheral neuropathy outcome measures standardization (PeriNomS) study. The following OMs were serially applied in 26 patients with newly diagnosed or relapsing MMN, receiving intravenous immunoglobulin (assessments: T0/T3/T12 months): 14 muscle pairs MRC (Medical Re... Abstract
Cited 27 times since 2015 (2.8 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 20, Issue 3, 1 1 2015, Pages 296-305 Rasch-built Overall Disability Scale for Multifocal motor neuropathy (MMN-RODS(©) ). Vanhoutte EK, Faber CG, van Nes SI, Cats EA, Van der Pol WL, Gorson KC, van Doorn PA, Cornblath DR, van den Berg LH, Merkies IS, PeriNomS Study Group
Clinical trials in multifocal motor neuropathy (MMN) have often used ordinal-based measures that may not accurately capture changes. We aimed to construct a disability interval outcome measure specifically for MMN using the Rasch model and to examine its clinimetric properties. A total of 146 preliminary activity and participation items were assessed twice (reliability studies) in 96 clinically stable MMN patients. These patients also assessed the ordinal-based overall disability sum score (cons... Abstract
Cited 33 times since 2015 (3.4 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 20, Issue 3, 1 1 2015, Pages 260-268 Rasch-ionale for neurologists. Vanhoutte EK, Hermans MC, Faber CG, Gorson KC, Merkies IS, Thonnard JL, PeriNomS Study Group
Outcome measures are considered the most important tools to monitor patients' outcome in both clinical and research settings. Measuring the clinical state of patients is a fundamental part of our daily clinical practice and research that sometimes is taken for granted. In peripheral neuropathies, there are many scales available, but most of these are at the ordinal level. This paper will systematically address the types of scales available (being nominal, ordinal, interval, or ratio data-ba... Abstract
Cited 24 times since 2015 (2.5 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 20, Issue 3, 1 1 2015, Pages 269-276 Grip strength comparison in immune-mediated neuropathies: Vigorimeter vs. Jamar. Draak TH, Pruppers MH, van Nes SI, Vanhoutte EK, Bakkers M, Gorson KC, Van der Pol WL, Lewis RA, Notermans NC, Nobile-Orazio E, Léger JM, Van den Bergh PY, Lauria G, Bril V, Katzberg H, Lunn MP, Pouget J, van der Kooi AJ, van den Berg LH, van Doorn PA, Cornblath DR, Hahn AF, Faber CG, Merkies IS, PeriNomS study group
The Jamar dynamometer and Vigorimeter have been used to assess grip strength in immune-mediated neuropathies, but have never been compared to each other. Therefore, we performed a comparison study between these two devices in patients with immune-mediated neuropathies. Grip strength data were collected in 102 cross-sectional stable and 163 longitudinal (new diagnoses or changing condition) patients with Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CID... Abstract
Cited 19 times since 2015 (1.9 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 20, Issue 3, 1 1 2015, Pages 277-288 Comparing the NIS vs. MRC and INCAT sensory scale through Rasch analyses. Draak TH, Vanhoutte EK, van Nes SI, Gorson KC, Van der Pol WL, Notermans NC, Nobile-Orazio E, Lewis RA, Léger JM, Van den Bergh PY, Lauria G, Bril V, Katzberg H, Lunn MP, Pouget J, van der Kooi AJ, Hahn AF, van den Berg LH, van Doorn PA, Cornblath DR, Faber CG, Merkies IS, PeriNomS Study Group
We performed a comparison between Neuropathy Impairment Scale-sensory (NISs) vs. the modified Inflammatory Neuropathy Cause and Treatment sensory scale (mISS), and NIS-motor vs. the Medical Research Council sum score in patients with Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and IgM monoclonal gammopathy of undetermined significance-related polyneuropathy (MGUSP). The ordinal data were subjected to Rasch analyses, creating Rasch-transformed... Abstract
Circulation. Cardiovascular imaging, Volume 8, Issue 9, 1 1 2015, Pages e003985 Cardiac Simulation to Personalize Cardiac Resynchronization Therapy. Delgado V, Bax JJ
European heart journal. Cardiovascular Imaging, Volume 16, Issue 9, 1 1 2015, Pages 959-965 Highlights of the 12th International Conference on Nuclear Cardiology and Cardiac CT. Kitsiou A, Dorbala S, Scholte AJ
The 12th International Conference on Nuclear Cardiology and Cardiac CT was held from 3 to 5 May 2015 in Madrid, Spain. In this article, the three Congress Program Committee Chairs summarize selected highlights of the presented abstracts. Abstract
Cited 1331 times since 2015 (136.3 per year) source: EuropePMC
The New England journal of medicine, Volume 373, Issue 10, 1 1 2015, Pages 929-938 Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. Templin C, Ghadri JR, Diekmann J, Napp LC, Bataiosu DR, Jaguszewski M, Cammann VL, Sarcon A, Geyer V, Neumann CA, Seifert B, Hellermann J, Schwyzer M, Eisenhardt K, Jenewein J, Franke J, Katus HA, Burgdorf C, Schunkert H, Moeller C, Thiele H, Bauersachs J, Tschöpe C, Schultheiss HP, Laney CA, Rajan L, Michels G, Pfister R, Ukena C, Böhm M, Erbel R, Cuneo A, Kuck KH, Jacobshagen C, Hasenfuss G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Cuculi F, Banning A, Fischer TA, Vasankari T, Airaksinen KE, Fijalkowski M, Rynkiewicz A, Pawlak M, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, Erne P, Bax JJ, Ford I, Ruschitzka F, Prasad A, Lüscher TF
Background: The natural history, management, and outcome of takotsubo (stress) cardiomyopathy are incompletely understood. Methods: The International Takotsubo Registry, a consortium of 26 centers in Europe and the United States, was established to investigate clinical features, prognostic predictors, and outcome of takotsubo cardiomyopathy. Patients were compared with age- and sex-matched patients who had an acute coronary syndrome. Results: Of 1750 patients with takotsubo cardiomyopathy, 89.8%... Abstract
Cited 5 times since 2015 (0.5 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 23, Issue 10, 1 1 2015, Pages 457-465 The year of transparency: measuring quality of cardiac care. Eindhoven DC, Wierda E, de Bruijne MC, Amoroso G, de Mol BAJM, Umans VAWM, Schalij MJ, Borleffs CJW
The assessment of quality of care is becoming increasingly important in healthcare, both globally and in the Netherlands. The Dutch Minister of Health declared 2015 to be the year of transparency, thereby aiming to improve quality of care by transparent reporting of outcome data. With the increasing importance of transparency, knowledge on quality measurement will be essential for a cardiologist in daily clinical care. To that end, this paper provides a comprehensive overview of the Dutch health... Abstract
Cited 7 times since 2015 (0.7 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 23, Issue 10, 1 1 2015, Pages 493-501 Coupling between MRI-assessed regional aortic pulse wave velocity and diameters in patients with thoracic aortic aneurysm: a feasibility study. Kröner ESJ, Westenberg JJM, Kroft LJM, Brouwer NJ, van den Boogaard PJ, Scholte AJHA
Aims: Thoracic aortic aneurysm (TAA) is potentially life-threatening and requires close follow-up to prevent aortic dissection. Aortic stiffness and size are considered to be coupled. Regional aortic stiffness in patients with TAA is unknown. We aimed to evaluate coupling between regional pulse wave velocity (PWV), a marker of vascular stiffness, and aortic diameter in TAA patients. Methods: In 40 TAA patients (59 ± 13 years, 28 male), regional aortic diameters and regional PWV were assessed by... Abstract
Cited 50 times since 2015 (5.1 per year) source: EuropePMC
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, Volume 187, Issue 15, 31 5 2015, Pages E442-E449 Resting heart rate, heart rate variability and functional decline in old age. Ogliari G, Mahinrad S, Stott DJ, Jukema JW, Mooijaart SP, Macfarlane PW, Clark EN, Kearney PM, Westendorp RGJ, de Craen AJM, Sabayan B
Background: Heart rate and heart rate variability, markers of cardiac autonomic function, have been linked with cardiovascular disease. We investigated whether heart rate and heart rate variability are associated with functional status in older adults, independent of cardiovascular disease. Methods: We obtained data from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). A total of 5042 participants were included in the present study, and mean follow-up was 3.2 years. Heart r... Abstract
Cited 4 times since 2015 (0.4 per year) source: EuropePMC
International journal of surgery case reports, Volume 15, 30 5 2015, Pages 133-136 Case report of nail bed injury after blunt trauma; what lies beneath the nail? Nanninga GL, de Leur K, van den Boom AL, de Vries MR, van Ginhoven TM
Introduction: A stable, mobile and sensate fingertip is of paramount importance to perform daily tasks and sense dangerous situations. Unfortunately, fingertips are easily injured with various extents of soft tissue damage. Delayed and inadequate treatment of nail bed injuries may cause substantial clinical problems. The aim is to increase awareness about nail bed injuries among physicians who often treat these patients. Presentation of case: We present a 26-year-old male with blunt trauma to a... Abstract
Cited 34 times since 2015 (3.5 per year) source: EuropePMC
European heart journal, Volume 37, Issue 1, 30 5 2015, Pages 49-59 Association of persistent or worsened echocardiographic dyssynchrony with unfavourable clinical outcomes in heart failure patients with narrow QRS width: a subgroup analysis of the EchoCRT trial. Gorcsan J, Sogaard P, Bax JJ, Singh JP, Abraham WT, Borer JS, Dickstein K, Gras D, Krum H, Brugada J, Robertson M, Ford I, Holzmeister J, Ruschitzka F
Aims: EchoCRT was a randomized trial of cardiac resynchronization therapy (CRT) in severely symptomatic heart failure (HF) patients with narrow QRS width Abstract
Cited 9 times since 2015 (0.9 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 31, Issue 8, 29 5 2015, Pages 1583-1590 Effect of statins on aortic root growth rate in patients with bicuspid aortic valve anatomy. Regeer MV, van Rosendael PJ, Kamperidis V, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Bicuspid aortic valve (BAV) anatomy is associated with increased growth rate of the aortic root compared to tricuspid aortic valves. Statins decrease the growth rate of abdominal aneurysms; however their effect on the aortic root growth rate has not been elucidated. The present study evaluated the association between use of statins and aortic root growth in patients with BAV. A total of 199 patients (43 ± 15 years, 69% male) with BAV who underwent ≥ 2 echocardiographic measurements of the aortic... Abstract