8684 results
Cited 1064 times since 2015 (108.8 per year)
source: EuropePMC
European heart journal,
Volume 36, Issue 42, 29 5 2015, Pages 2921-2964
2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS).
Adler Y, Charron P, Imazio M, Badano L, Barón-Esquivias G, Bogaert J, Brucato A, Gueret P, Klingel K, Lionis C, Maisch B, Mayosi B, Pavie A, Ristic AD, Sabaté Tenas M, Seferovic P, Swedberg K, Tomkowski W, ESC Scientific Document Group
Abstract
Cited 3251 times since 2015 (332.5 per year)
source: EuropePMC
European heart journal,
Volume 37, Issue 1, 29 5 2015, Pages 67-119
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).
Galiè N, Humbert M, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, Simonneau G, Peacock A, Vonk Noordegraaf A, Beghetti M, Ghofrani A, Gomez Sanchez MA, Hansmann G, Klepetko W, Lancellotti P, Matucci M, McDonagh T, Pierard LA, Trindade PT, Zompatori M, Hoeper M, ESC Scientific Document Group
Abstract
Cited 2378 times since 2015 (243.2 per year)
source: EuropePMC
European heart journal,
Volume 36, Issue 44, 29 5 2015, Pages 3075-3128
2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM).
Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos-Hesselink J, Snygg-Martin U, Thuny F, Tornos Mas P, Vilacosta I, Zamorano JL, ESC Scientific Document Group
Abstract
Cited 2399 times since 2015 (245.4 per year)
source: EuropePMC
European heart journal,
Volume 37, Issue 3, 29 5 2015, Pages 267-315
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC).
Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S, ESC Scientific Document Group
Abstract
Cited 1625 times since 2015 (166.2 per year)
source: EuropePMC
European heart journal,
Volume 36, Issue 41, 29 5 2015, Pages 2793-2867
2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC).
Priori SG, Blomström-Lundqvist C, Mazzanti A, Blom N, Borggrefe M, Camm J, Elliott PM, Fitzsimons D, Hatala R, Hindricks G, Kirchhof P, Kjeldsen K, Kuck KH, Hernandez-Madrid A, Nikolaou N, Norekvål TM, Spaulding C, Van Veldhuisen DJ, ESC Scientific Document Group
Abstract
Cited 20 times since 2015 (2 per year)
source: EuropePMC
American journal of primatology,
Volume 77, Issue 11, 28 4 2015, Pages 1216-1229
Why do orangutans leave the trees? Terrestrial behavior among wild Bornean orangutans (Pongo pygmaeus wurmbii) at Tuanan, Central Kalimantan.
Ashbury AM, Posa MR, Dunkel LP, Spillmann B, Atmoko SS, van Schaik CP, van Noordwijk MA
Orangutans (genus Pongo) are the largest arboreal mammals, but Bornean orangutans (P. pygmaeus spp.) also spend time on the ground. Here, we investigate ground use among orangutans using 32,000 hr of direct focal animal observations from a well-habituated wild population of Bornean orangutans (P. p. wurmbii) living in a closed-canopy swamp forest at Tuanan, Central Kalimantan, Indonesia. Ground use did not change with increasing observation time of well-habituated individuals, suggesting it was...
Abstract
Cited 22 times since 2015 (2.2 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 28, Issue 12, 22 4 2015, Pages 1379-89.e1
Quantitative Dobutamine Stress Echocardiography Using Speckle-Tracking Analysis versus Conventional Visual Analysis for Detection of Significant Coronary Artery Disease after ST-Segment Elevation Myocardial Infarction.
Joyce E, Hoogslag GE, Al Amri I, Debonnaire P, Katsanos S, Bax JJ, Delgado V, Marsan NA
Background: Residual ischemia detection after ST-segment elevation myocardial infarction (STEMI) during dobutamine stress echocardiography (DSE) using visual analysis is challenging. The aim of the present study was to investigate the feasibility and accuracy of two-dimensional speckle-tracking strain DSE to detect significant coronary artery disease (CAD) after STEMI. Methods: First STEMI patients (n = 105; mean age, 60 ± 11 years; 86% men) treated with primary percutaneous coronary interventio...
Abstract
Cited 171 times since 2015 (17.5 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 42, Issue 12, 21 3 2015, Pages 1929-1940
EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision.
Verberne HJ, Acampa W, Anagnostopoulos C, Ballinger J, Bengel F, De Bondt P, Buechel RR, Cuocolo A, van Eck-Smit BL, Flotats A, Hacker M, Hindorf C, Kaufmann PA, Lindner O, Ljungberg M, Lonsdale M, Manrique A, Minarik D, Scholte AJ, Slart RH, Trägårdh E, de Wit TC, Hesse B, European Association of Nuclear Medicine (EANM)
Since the publication of the European Association of Nuclear Medicine (EANM) procedural guidelines for radionuclide myocardial perfusion imaging (MPI) in 2005, many small and some larger steps of progress have been made, improving MPI procedures. In this paper, the major changes from the updated 2015 procedural guidelines are highlighted, focusing on the important changes related to new instrumentation with improved image information and the possibility to reduce radiation exposure, which is fur...
Abstract
Cited 23 times since 2015 (2.3 per year)
source: EuropePMC
International journal of antimicrobial agents,
Volume 46, Issue 5, 20 3 2015, Pages 572-575
Deletions in a ribosomal protein-coding gene are associated with tigecycline resistance in Enterococcus faecium.
Niebel M, Quick J, Prieto AM, Hill RL, Pike R, Huber D, David M, Hornsey M, Wareham D, Oppenheim B, Woodford N, van Schaik W, Loman N
Enterococcus faecium is an emerging nosocomial pathogen associated with antibiotic therapy in the hospital environment. Whole-genome sequences were determined for three pairs of related, consecutively collected E. faecium clinical isolates to determine putative mechanisms of resistance to tigecycline. The first isolates (1S, 2S and 3S) in each of the three pairs were sensitive to tigecycline [minimum inhibitory concentration (MIC) of 0.125 mg/L]. Following tigecycline therapy, the second isolate...
Abstract
Cited 2 times since 2015 (0.2 per year)
source: EuropePMC
European biophysics journal : EBJ,
Volume 44, Issue 7, 19 3 2015, Pages 557-565
Study of light-induced MscL gating by EPR spectroscopy.
Yilmaz D, Dimitrova AI, Walko M, Kocer A
A number of techniques developed to investigate protein structure and function depend on chemically modifying and/or labeling of proteins. However, in the case of homooligomeric proteins, the presence of multiple identical subunits obstructs the introduction of residue-specific labels to only one or several subunits, selectively. Here, in order to study the initial conformational changes of a homopentameric mechanosensitive ion channel during its gating, we developed a method for labeling a defi...
Abstract
Cited 9 times since 2015 (0.9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 16, Issue 10, 19 3 2015, Pages 1062-1064
Detection of viable myocardium and scar tissue.
Bax JJ, Delgado V
Abstract
Cited 21 times since 2015 (2.1 per year)
source: EuropePMC
Journal of affective disorders,
Volume 187, 18 3 2015, Pages 54-61
Adding mindfulness-based cognitive therapy to maintenance antidepressant medication for prevention of relapse/recurrence in major depressive disorder: Randomised controlled trial.
Huijbers MJ, Spinhoven P, Spijker J, Ruhé HG, van Schaik DJ, van Oppen P, Nolen WA, Ormel J, Kuyken W, van der Wilt GJ, Blom MB, Schene AH, Donders AR, Speckens AE
Background: Mindfulness-based cognitive therapy (MBCT) and maintenance antidepressant medication (mADM) both reduce the risk of relapse in recurrent depression, but their combination has not been studied. Our aim was to investigate whether the addition of MBCT to mADM is a more effective prevention strategy than mADM alone. Methods: This study is one of two multicenter randomised trials comparing the combination of MBCT and mADM to either intervention on its own. In the current trial, recurrentl...
Abstract
Cited 1 times since 2015 (0.1 per year)
source: EuropePMC
Psychiatry research,
Volume 229, Issue 3, 15 3 2015, Pages 678-684
Viral metagenomics in drug-naïve, first-onset schizophrenia patients with prominent negative symptoms.
Canuti M, van Beveren NJ, Jazaeri Farsani SM, de Vries M, Deijs M, Jebbink MF, Zaaijer HL, van Schaik BD, van Kampen AH, van der Kuyl AC, de Haan L, Storosum JG, van der Hoek L
Although several studies suggest a virus or (endogenous) retrovirus involvement at the time of onset of schizophrenia, the unequivocal identification of one or more infectious agents, by means of an undirected catch-all technique, has never been conducted. In this study VIDISCA, a virus discovery method, was used in combination with Roche-454 high-throughput sequencing as a tool to determine the possible presence of viruses (known or unknown) in blood of first-onset drugs-naïve schizophrenic pat...
Abstract
Cited 14 times since 2015 (1.4 per year)
source: EuropePMC
The American journal of cardiology,
Volume 116, Issue 9, 14 2 2015, Pages 1334-1339
Comparison of Changes in Global Longitudinal Peak Systolic Strain After ST-Segment Elevation Myocardial Infarction in Patients With Versus Without Diabetes Mellitus.
Hoogslag GE, Abou R, Joyce E, Boden H, Kamperidis V, Regeer MV, van Rosendael PJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Global longitudinal strain (GLS) measured by 2-dimensional longitudinal speckle-tracking echocardiography may be a more sensitive measure of left ventricular (LV) mechanics than conventional LV ejection fraction (EF) to characterize adverse post-ST-segment elevation myocardial infarction (STEMI) remodeling. The aim of the present evaluation was to compare changes in LV GLS in patients with versus without diabetes after the first STEMI. Patients with first STEMI and diabetes (n = 143; age 64 ± 12...
Abstract
Cited 26 times since 2015 (2.6 per year)
source: EuropePMC
Journal of dairy science,
Volume 98, Issue 10, 13 2 2015, Pages 6965-6977
An estimation of the clinical mastitis incidence per 100 cows per year based on routinely collected herd data.
Santman-Berends IM, Lam TJ, Keurentjes J, van Schaik G
The aim of this study was to evaluate whether it was possible to (1) estimate the clinical mastitis incidence rate (CMI) for all Dutch dairy herds and (2) to detect farms with a high CMI based on routinely collected herd data. For this study, 240 dairy farms with a conventional milking system that participated in the milk recording program every 4 to 6 wk were randomly selected and agreed to participate. From the initial 240 herds, data of clinical mastitis (CM) registrations and routinely colle...
Abstract
Cited 7 times since 2015 (0.7 per year)
source: EuropePMC
The British journal of surgery,
Volume 102, Issue 11, 12 2 2015, Pages 1338-1347
Multicentre randomized clinical trial to investigate the cost-effectiveness of an allogeneic single-donor fibrin sealant after coronary artery bypass grafting (FIBER Study).
Tavilla G, Bruggemans EF, Gielen CL, Brand A, van den Hout WB, Klautz RJ, van Hilten JA
Background: Reduction of blood transfusion in cardiac surgery is an important target. The aim of this study was to investigate the cost-effectiveness of the use of CryoSeal®, an allogeneic single-donor fibrin sealant, in patients undergoing coronary artery bypass grafting (CABG). Methods: This randomized clinical study involved seven cardiac surgery centres in the Netherlands. Patients undergoing elective isolated CABG with the use of at least one internal thoracic artery (ITA) graft were assign...
Abstract
Cited 12 times since 2015 (1.2 per year)
source: EuropePMC
Pharmacogenomics,
Volume 16, Issue 11, 12 2 2015, Pages 1231-1241
Predicting paclitaxel-induced neutropenia using the DMET platform.
Nieuweboer AJ, Smid M, de Graan AJ, Elbouazzaoui S, de Bruijn P, Martens JW, Mathijssen RH, van Schaik RH
Aim: The use of paclitaxel in cancer treatment is limited by paclitaxel-induced neutropenia. We investigated the ability of genetic variation in drug-metabolizing enzymes and transporters to predict hematological toxicity. Patients & methods: Using a discovery and validation approach, we identified a pharmacogenetic predictive model for neutropenia. For this, a drug-metabolizing enzymes and transporters plus DNA chip was used, which contains 1936 SNPs in 225 metabolic enzyme and drug-transpo...
Abstract
Cited 12 times since 2015 (1.2 per year)
source: EuropePMC
British journal of clinical pharmacology,
Volume 80, Issue 3, 12 2 2015, Pages 560-568
4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes.
de Graan AJ, Sparreboom A, de Bruijn P, de Jonge E, van der Holt B, Wiemer EA, Verweij J, Mathijssen RH, van Schaik RH
Aim: Taxanes are anti-cancer agents used to treat several types of solid tumours. They are metabolized by cytochrome P450 (CYP) 3A, displaying a large pharmacokinetic (PK) variability. In this study, we evaluated the endogenous CYP3A4 marker 4β-hydroxycholesterol (4β-OHC) as a potential individual taxane PK predictor. Methods: Serum 4β-OHC and cholesterol concentrations were determined in 291 paclitaxel and 151 docetaxel-treated patients, and were subsequently correlated with taxane clearance. R...
Abstract
Cited 40 times since 2015 (4.1 per year)
source: EuropePMC
BMJ open,
Volume 5, Issue 8, 11 2 2015, Pages e008808
Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium.
Morris RW, Taylor AE, Fluharty ME, Bjørngaard JH, Åsvold BO, Elvestad Gabrielsen M, Campbell A, Marioni R, Kumari M, Korhonen T, Männistö S, Marques-Vidal P, Kaakinen M, Cavadino A, Postmus I, Husemoen LL, Skaaby T, Ahluwalia TV, Treur JL, Willemsen G, Dale C, Wannamethee SG, Lahti J, Palotie A, Räikkönen K, McConnachie A, Padmanabhan S, Wong A, Dalgård C, Paternoster L, Ben-Shlomo Y, Tyrrell J, Horwood J, Fergusson DM, Kennedy MA, Nohr EA, Christiansen L, Kyvik KO, Kuh D, Watt G, Eriksson JG, Whincup PH, Vink JM, Boomsma DI, Davey Smith G, Lawlor D, Linneberg A, Ford I, Jukema JW, Power C, Hyppönen E, Jarvelin MR, Preisig M, Borodulin K, Kaprio J, Kivimaki M, Smith BH, Hayward C, Romundstad PR, Sørensen TI, Munafò MR, Sattar N
Objectives: To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity. Design: Mendelian randomisation meta-analyses using a genetic variant (rs16969968/rs1051730 in the CHRNA5-CHRNA3-CHRNB4 gene region) as a proxy for smoking heaviness, of the associations of smoking heaviness with a range of adiposity phenotypes. Participants: 148,731 current, former and never...
Abstract
Cited 10 times since 2015 (1 per year)
source: EuropePMC
PloS one,
Volume 10, Issue 8, 11 2 2015, Pages e0134254
Fast, Simple and Accurate Handwritten Digit Classification by Training Shallow Neural Network Classifiers with the 'Extreme Learning Machine' Algorithm.
McDonnell MD, Tissera MD, Vladusich T, van Schaik A, Tapson J
Recent advances in training deep (multi-layer) architectures have inspired a renaissance in neural network use. For example, deep convolutional networks are becoming the default option for difficult tasks on large datasets, such as image and speech recognition. However, here we show that error rates below 1% on the MNIST handwritten digit benchmark can be replicated with shallow non-convolutional neural networks. This is achieved by training such networks using the 'Extreme Learning Machine...
Abstract
