Research

Publications

Below you can find a list of our published research.

7995 results

Cited 26 times since 2013 (2.3 per year) source: EuropePMC

Respiratory medicine, Volume 108, Issue 2, 10 2 2013, Pages 351-357 Association of lung function measurements and visceral fat in men with metabolic syndrome. Thijs W, Alizadeh Dehnavi R, Hiemstra PS, de Roos A, Melissant CF, Janssen K, Tamsma JT, Rabe KF

Background: Several studies have reported a positive relationship between lung function impairment and the metabolic syndrome. This is most usually explained by abdominal adiposity. We hypothesized that the main determinant of the association between lung function impairment and abdominal obesity is the presence of visceral fat. Methods: The present study is a cross-sectional analysis of 98 non-diabetic men aged between 50 and 70 years with the metabolic syndrome. The amount of visceral and subc... Abstract

Cited 15 times since 2013 (1.3 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 33, Issue 12, 10 2 2013, Pages 2810-2817 An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation. Karper JC, de Jager SC, Ewing MM, de Vries MR, Bot I, van Santbrink PJ, Redeker A, Mallat Z, Binder CJ, Arens R, Jukema JW, Kuiper J, Quax PH

Objective: In atherosclerosis, Toll-like receptors (TLRs) are traditionally linked to effects on tissue macrophages or foam cells. RP105, a structural TLR4 homolog, is an important regulator of TLR signaling. The effects of RP105 on TLR signaling vary for different leukocyte subsets known to be involved in atherosclerosis, making it unique in its role of either suppressing (in myeloid cells) or enhancing (in B cells) TLR-regulated inflammation in different cell types. We aimed to identify a role... Abstract

Cited 12 times since 2013 (1.1 per year) source: EuropePMC

Journal of sex & marital therapy, Volume 40, Issue 4, 8 2 2013, Pages 309-322 Quality of sexual life and its effect on marital adjustment of Turkish women in pregnancy. Kisa S, Zeyneloğlu S, Yilmaz D, Güner T

Pregnancy is an important period of a woman's life that can affect marital relationships because of decrease in the sexual function. This study aimed to examine the effect of sexual life on the marital adjustment of 607 healthy, pregnant women using the self-administered Sexual Quality of Life Questionnaire-Female and the Marital Adjustment Scale. Results showed that 30% of the pregnant women experienced problems during sexual intercourse and 50% had painful intercourse. The median total sc... Abstract

Cited 37 times since 2013 (3.2 per year) source: EuropePMC

Head & neck, Volume 36, Issue 6, 4 1 2013, Pages 853-858 Intraoperative near-infrared fluorescence imaging of parathyroid adenomas with use of low-dose methylene blue. van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Tummers QR, Hutteman M, Hamming JF, Kievit J, Frangioni JV, van de Velde CJ, Vahrmeijer AL

Background: Intraoperative identification of parathyroid adenomas can be challenging. We hypothesized that low-doses methylene blue (MB) and near-infrared fluorescence (NIRF) imaging could be used to identify parathyroid adenomas intraoperatively. Methods: MB was injected intravenously after exploration at a dose of 0.5 mg/kg into 12 patients who underwent parathyroid surgery. NIRF imaging was performed using the Mini-FLARE imaging system. Results: In 10 of 12 patients, histology confirmed a par... Abstract

Cited 10 times since 2013 (0.9 per year) source: EuropePMC

Injury, Volume 45, Issue 4, 3 1 2013, Pages 696-700 Which factors affect limitation of pronation/supination after forearm fractures in children? A prospective multicentre study. Colaris JW, Allema JH, Reijman M, de Vries MR, Ulas Biter L, Bloem RM, van de Ven CP, Verhaar JA

Introduction: Both-bone forearm fractures in children frequently result in a limitation of pronation/supination, which hinders daily activities. The purpose of this prospective multicentre study was to investigate which clinical factors are related to the limitation of pronation/supination in children with a both-bone forearm fracture. Methods: In four Dutch hospitals, consecutive children ( Abstract

Cited 4 times since 2013 (0.4 per year) source: EuropePMC

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Volume 28, Issue 12, 3 1 2013, Pages 3045-3052 Echocardiographical determinants of an abnormal spatial QRS-T angle in chronic dialysis patients. de Bie MK, Ajmone Marsan N, Gaasbeek A, Bax JJ, Delgado V, Rabelink TJ, Schalij MJ, Jukema JW

Background: The spatial QRS-T angle describes the relation between ventricular depolarization and repolarization. Having a wide (abnormal) angle is considered an important predictor of arrhythmic events. Given the high incidence of sudden cardiac death in dialysis patients, this parameter is of particular interest in this patient group. The objective of this study was to assess the association of (modifiable) echocardiographic parameters and an abnormal spatial QRS-T angle in dialysis patients.... Abstract

Cited 2 times since 2013 (0.2 per year) source: EuropePMC

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 46, Issue 6, 2 1 2013, Pages 719-725 Vascular training profiles across Europe. Avgerinos ED, European Vascular Surgeons in Training (EVST) Writing Committee

Background: The European Vascular Surgeons in Training (EVST) were appointed by the European Society for Vascular Surgery to review the current status and developments regarding training and certification in vascular surgery (VS) across Europe. Methods: An e-mail-based survey was distributed to EVST representatives in 33 countries. The questionnaire examined the current structure of vascular surgery training and certification (monospecialty, subspecialty, no specialty), as well as the evolving r... Abstract

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 9, Issue 6, 1 1 2013, Pages 761-4, 3 p following p764 How should I treat acute left main coronary obstruction after transapical aortic valve implantation? Nazeri I, Abdi S, Mandegar MH, Naemi S, Roshanali F, Tehrai M, Shahabi P, Debonnaire P, van der Kley F, Katsanos S, Delgado V, Van Mieghem NM

Abstract

Cited 10 times since 2013 (0.9 per year) source: EuropePMC

Cardiovascular drugs and therapy, Volume 27, Issue 5, 1 1 2013, Pages 433-439 Long term effects of epoetin alfa in patients with ST- elevation myocardial infarction. Fokkema ML, Kleijn L, van der Meer P, Belonje AM, Achterhof SK, Hillege HL, van 't Hof A, Jukema JW, Peels HO, Henriques JP, ten Berg JM, Vos J, van Gilst WH, van Veldhuisen DJ, Voors AA

Purpose: The HEBE III trial showed that epoetin alfa administration in patients with a first ST-elevation myocardial infarction (STEMI) did not improve left ventricular function at 6 weeks after primary percutaneous coronary intervention (PCI). The long term effects of erythropoiesis- stimulating agents on cardiovascular morbidity and mortality are unknown, therefore we evaluated clinical events at 1 year after PCI. Methods: A total of 529 patients with a first STEMI and successful primary PCI w... Abstract

Cited 4 times since 2013 (0.4 per year) source: EuropePMC

Indian dermatology online journal, Volume 4, Issue 4, 1 1 2013, Pages 369-371 A cases series of Piezogenic pedal papules. Karadag AS, Bilgili SG, Guner S, Yilmaz D

Abstract

Cited 8 times since 2013 (0.7 per year) source: EuropePMC

Journal of African earth sciences (Oxford, England : 1994), Volume 86, 1 1 2013, Pages 65-106 Orogen styles in the East African Orogen: A review of the Neoproterozoic to Cambrian tectonic evolution. Fritz H, Abdelsalam M, Ali KA, Bingen B, Collins AS, Fowler AR, Ghebreab W, Hauzenberger CA, Johnson PR, Kusky TM, Macey P, Muhongo S, Stern RJ, Viola G

The East African Orogen, extending from southern Israel, Sinai and Jordan in the north to Mozambique and Madagascar in the south, is the world́s largest Neoproterozoic to Cambrian orogenic complex. It comprises a collage of individual oceanic domains and continental fragments between the Archean Sahara-Congo-Kalahari Cratons in the west and Neoproterozoic India in the east. Orogen consolidation was achieved during distinct phases of orogeny between ∼850 and 550 Ma. The northern part of the oroge... Abstract

Cited 49 times since 2013 (4.3 per year) source: EuropePMC

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Volume 33, Issue 4, 29 5 2013, Pages 479-490 Determinants of virulence of influenza A virus. Schrauwen EJ, de Graaf M, Herfst S, Rimmelzwaan GF, Osterhaus AD, Fouchier RA

Influenza A viruses cause yearly seasonal epidemics and occasional global pandemics in humans. In the last century, four human influenza A virus pandemics have occurred. Occasionally, influenza A viruses that circulate in other species cross the species barrier and infect humans. Virus reassortment (i.e. mixing of gene segments of multiple viruses) and the accumulation of mutations contribute to the emergence of new influenza A virus variants. Fortunately, most of these variants do not have the... Abstract

Cited 5 times since 2013 (0.4 per year) source: EuropePMC

Heart and vessels, Volume 29, Issue 5, 27 4 2013, Pages 619-628 Prognostic implications of left ventricular regional function heterogeneity assessed with two-dimensional speckle tracking in patients with ST-segment elevation myocardial infarction and depressed left ventricular ejection fraction. Hoogslag GE, Thijssen J, Höke U, Boden H, Antoni ML, Debonnaire P, Haeck ML, Holman ER, Bax JJ, Ajmone Marsan N, Schalij MJ, Delgado V

The aim of the current study was to evaluate the prognostic implications of myocardial tissue heterogeneity assessed with two-dimensional speckle-tracking echocardiography in patients three months after first ST-segment elevation myocardial infarction (STEMI) with left ventricular ejection fraction (LVEF) ≤35 %. For this purpose, a total of 79 patients with first STEMI and LVEF ≤35 % at three months postinfarction were evaluated. Based on left ventricular (LV) speckle-tracking longitudinal strai... Abstract

Cited 7 times since 2013 (0.6 per year) source: Scopus

Interactive cardiovascular and thoracic surgery, Volume 18, Issue 1, 26 4 2013, Pages 33-37 Primary closure using Redon drains for the treatment of post-sternotomy mediastinitis. Vos RJ, van Putte BP, Sonker U, Kloppenburg GT

Objectives: Post-sternotomy mediastinitis is a severe complication of open heart surgery resulting in prolonged hospital stay and increased mortality. Vacuum-assisted closure is commonly used as treatment for post-sternotomy mediastinitis, but has some disadvantages. Primary closure over high vacuum suction Redon drains previously has shown to be an alternative approach with promising results. We report our short- and long-term results of Redon therapy-treated mediastinitis. Methods: We performe... Abstract

American heart journal, Volume 166, Issue 5, 24 4 2013, Pages e43 Reply to letter to the editor by Koza et al. Kooiman J, le Haen PA, Gezgin G, de Vries JP, Boersma D, Brulez HF, Sijpkens YW, van der Molen AJ, Cannegieter SC, Hamming JF, Huisman MV

Abstract

Cited 27 times since 2013 (2.4 per year) source: EuropePMC

Circulation, Volume 128, Issue 25, 24 4 2013, Pages 2732-2744 Atrium-specific Kir3.x determines inducibility, dynamics, and termination of fibrillation by regulating restitution-driven alternans. Bingen BO, Neshati Z, Askar SF, Kazbanov IV, Ypey DL, Panfilov AV, Schalij MJ, de Vries AA, Pijnappels DA

Background: Atrial fibrillation is the most common cardiac arrhythmia. Ventricular proarrhythmia hinders pharmacological atrial fibrillation treatment. Modulation of atrium-specific Kir3.x channels, which generate a constitutively active current (I(K,ACh-c)) after atrial remodeling, might circumvent this problem. However, it is unknown whether and how I(K,ACh-c) contributes to atrial fibrillation induction, dynamics, and termination. Therefore, we investigated the effects of I(K,ACh-c) blockade... Abstract

Cited 46 times since 2013 (4 per year) source: EuropePMC

The American journal of cardiology, Volume 112, Issue 12, 21 3 2013, Pages 1867-1872 Outcome after ST elevation myocardial infarction in patients with cancer treated with primary percutaneous coronary intervention. Velders MA, Boden H, Hofma SH, Osanto S, van der Hoeven BL, Heestermans AA, Cannegieter SC, Jukema JW, Umans VA, Schalij MJ, van Boven AJ

The simultaneous occurrence of cancer and coronary heart disease is increasing in the Western world. Nevertheless, the influence of cancer on ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) has not been investigated extensively. This multicenter registry included patients with STEMI treated with primary PCI from 2006 to 2009. Patients were stratified according to history of cancer, and primary focus lay on all-cause and cardiac mortalities... Abstract

Cited 18 times since 2013 (1.6 per year) source: EuropePMC

PloS one, Volume 8, Issue 9, 19 3 2013, Pages e75573 Erythrocyte-bound apolipoprotein B in relation to atherosclerosis, serum lipids and ABO blood group. Klop B, van de Geijn GJ, Bovenberg SA, van der Meulen N, Elte JW, Birnie E, Njo TL, Janssen HW, van Miltenburg A, Jukema JW, Cabezas MC

Introduction: Erythrocytes carry apolipoprotein B on their membrane, but the determining factors of erythrocyte-bound apolipoprotein B (ery-apoB) are unknown. We aimed to explore the determinants of ery-apoB to gain more insight into potential mechanisms. Methods: Subjects with and without CVD were included (N = 398). Ery-apoB was measured on fresh whole blood samples using flow cytometry. Subjects with ery-apoB levels ≤ 0.20 a.u. were considered deficient. Carotid intima media thickness (CIMT)... Abstract

Cited 59 times since 2013 (5.1 per year) source: EuropePMC

PloS one, Volume 8, Issue 9, 16 3 2013, Pages e74083 BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality. Boon MR, van den Berg SA, van den Berg SA, Wang Y, van den Bossche J, Karkampouna S, Bauwens M, De Saint-Hubert M, van der Horst G, Vukicevic S, de Winther MP, Havekes LM, Jukema JW, Tamsma JT, van der Pluijm G, van Dijk KW, Rensen PC

Background/aims: Brown adipose tissue (BAT) dissipates energy stored in triglycerides as heat via the uncoupling protein UCP-1 and is a promising target to combat hyperlipidemia and obesity. BAT is densely innervated by the sympathetic nervous system, which increases BAT differentiation and activity upon cold exposure. Recently, Bone Morphogenetic Protein 7 (BMP7) was identified as an inducer of BAT differentiation. We aimed to elucidate the role of sympathetic activation in the effect of BMP7 o... Abstract

Cited 12 times since 2013 (1 per year) source: EuropePMC

Journal of surgical education, Volume 71, Issue 2, 14 2 2013, Pages 222-228 Quality of life of surgical oncology residents and fellows across Europe. Mordant P, Deneuve S, Rivera C, Carrabin N, Mieog JS, Malyshev N, Van Der Vorst JR, Audisio RA, French Association of Young Surgical Oncologists (AJCO), European Society of Surgical Oncology Young Surgeons and Alumni Club (EYSAC)

Background: Data are currently lacking regarding the quality of life of surgical oncology (SO) trainees. We sought to assess the training conditions and quality of life of SO residents and fellows across Europe. Material and methods: Members of the European Society for Surgical Oncology were invited to complete a Web-based survey that included a questionnaire specifically designed for SO trainees. Demographics, timing, and incentive to choose for SO, quality of life, and symptoms of fatigue, sle... Abstract