Research

Publications

Below you can find a list of our published research.

6136 results

Cited 4 times since 2016 (0.5 per year) source: EuropePMC

Congenital heart disease, Volume 12, Issue 1, 25 4 2016, Pages 32-39 Surgical outcome in pediatric patients with Ebstein's anomaly: A multicenter, long-term study. Geerdink LM, du Marchie Sarvaas GJ, Kuipers IM, Helbing WA, Delhaas T, Ter Heide H, Rozendaal L, de Korte CL, Singh SK, Ebels T, Hazekamp MG, Haas F, Bogers AJ, Kapusta L

Objective: Surgical outcomes of pediatric patients with Ebstein's anomaly are often described as part of all-age-inclusive series. Our objective is to focus on patients treated surgically in childhood (0-18 y). We study the intended treatment (biventricular or 1.5 ventricle repair or univentricular palliation), freedom from unplanned reoperation and survival of this specific age group, in a nationwide study. Design: Records of all Ebstein's anomaly patients born between 1980 and 2013 w... Abstract

Angiology, Volume 68, Issue 6, 23 4 2016, Pages 519-527 Very Long-Term Follow-Up After Coronary Rotational Atherectomy: A Single-Center Experience. Tohamy A, Klomp M, Putter H, Youssef A, Shams-Eddin H, Abdelsabour M, Schalij MJ, Jukema JW

We assessed the very long-term follow-up of a large cohort of unselected patients treated with coronary rotational atherectomy (RA). All 143 patients who underwent RA at our institution from 2000 to 2013 and with complete baseline and follow-up information were analyzed in a retrospective manner. Major adverse cardiac events (MACE) were defined as the composite of target vessel revascularization (TVR), acute myocardial infarction, and all-cause mortality. The mean follow-up was 8.2 years. The 10... Abstract

Cited 15 times since 2016 (1.8 per year) source: EuropePMC

The American journal of cardiology, Volume 118, Issue 10, 23 4 2016, Pages 1533-1538 Comparison of Quantity of Calcific Deposits by Multidetector Computed Tomography in the Aortic Valve and Coronary Arteries. van Rosendael PJ, Kamperidis V, Kong WK, van Rosendael AR, Marsan NA, Bax JJ, Delgado V

The aim of this study was to compare the calcium burden of the aortic valve and coronary arteries with multidetector computed tomography (MDCT) in a propensity score-matched population of patients with a bicuspid versus a tricuspid aortic valve. From an ongoing clinical registry of patients who underwent MDCT, 70 patients with bicuspid aortic valve and 210 patients with tricuspid aortic valve were matched based on age, gender, cardiovascular risk factors, chest pain symptoms, and MDCT indication... Abstract

Cited 8 times since 2016 (0.9 per year) source: EuropePMC

The British journal of dermatology, Volume 175, Issue 6, 19 3 2016, Pages 1357-1360 Ulcerated infantile haemangiomas: the effect of the selective beta-blocker atenolol on wound healing. Ruitenberg G, Young-Afat DA, de Graaf M, Pasmans SG, Breugem CC

Abstract

Cited 177 times since 2016 (20.7 per year) source: EuropePMC

Circulation research, Volume 119, Issue 9, 16 3 2016, Pages 996-1003 RBM20 Regulates Circular RNA Production From the Titin Gene. Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM

Rationale: RNA-binding motif protein 20 (RBM20) is essential for normal splicing of many cardiac genes, and loss of RBM20 causes dilated cardiomyopathy. Given its role in splicing, we hypothesized an important role for RBM20 in forming circular RNAs (circRNAs), a novel class of noncoding RNA molecules. Objective: To establish the role of RBM20 in the formation of circRNAs in the heart. Methods and results: Here, we performed circRNA profiling on ribosomal depleted RNA from human hearts and ident... Abstract

Cited 2 times since 2016 (0.2 per year) source: EuropePMC

Cardiovascular revascularization medicine : including molecular interventions, Volume 18, Issue 1, 8 2 2016, Pages 66-69 Guide extension catheter stepwise advancement facilitated by repeated distal balloon anchoring. Andreou C, Karalis I, Maniotis C, Jukema JW, Koutouzis M

Coronary stent delivery can be extremely challenging in tortuous and calcified lesions especially when radial approach is chosen. Guide extension catheter is a useful tool for overcoming the inherent difficulties arising by the use of radial access in complex percutaneous interventions. We describe a technique for guide extension catheter system advancement by presenting two cases. This was performed stepwise by repeated distal balloon anchoring in the coronary artery of interest. Abstract

Cited 7 times since 2016 (0.8 per year) source: EuropePMC

Journal of dairy science, Volume 99, Issue 10, 8 2 2016, Pages 8282-8296 Improving the time efficiency of identifying dairy herds with poorer welfare in a population. de Vries M, Bokkers EAM, van Schaik G, Engel B, Dijkstra T, de Boer IJM

Animal-based welfare assessment is time consuming and expensive. A promising strategy for improving the efficiency of identifying dairy herds with poorer welfare is to first estimate levels of welfare in herds based on data that are more easily obtained. Our aims were to evaluate the potential of herd housing and management data for estimating the level of welfare in dairy herds, and to estimate the associated reduction in the number of farm visits required for identification of herds with poore... Abstract

Cited 17 times since 2016 (2 per year) source: EuropePMC

Expert review of medical devices, Volume 13, Issue 9, 8 2 2016, Pages 823-830 Mobile health in cardiology: a review of currently available medical apps and equipment for remote monitoring. Treskes RW, van der Velde ET, Barendse R, Bruining N

Introduction: Recent developments in implantable cardioverter-defibrillators (ICDs) and smartphone technology have increased the possibilities for remote monitoring. It is the purpose of this review to give an overview of these new possibilities. Areas covered: Remote monitoring in ICD allows for early detection of lead fractures and remote follow-up of patients. Possible limitations are the lack of standardization and the possible unsafety of the data stored on the ICD. Secondly, remote monitor... Abstract

Cited 9 times since 2016 (1 per year) source: EuropePMC

Arrhythmia & electrophysiology review, Volume 5, Issue 2, 1 1 2016, Pages 150-160 Anatomical Substrates and Ablation of Reentrant Atrial and Ventricular Tachycardias in Repaired Congenital Heart Disease. Brouwer C, Hazekamp MG, Zeppenfeld K

Advances in surgical repair techniques for various types of congenital heart disease have improved survival into adulthood over the past decades, thus exposing these patients to a high risk of atrial and ventricular arrhythmias later in life. These arrhythmias arise from complex arrhythmogenic substrates. Substrate formation may depend on both pathological myocardial remodelling and variable anatomical boundaries, determined by the type and timing of prior corrective surgery. Accordingly, arrhyt... Abstract

Cited 4 times since 2016 (0.5 per year) source: EuropePMC

Interactive cardiovascular and thoracic surgery, Volume 23, Issue 6, 1 1 2016, Pages 979-981 Left ventricular assist device implantation in patients after left ventricular reconstruction. Palmen M, Braun J, Beeres SL, Klautz RJ

Left ventricular assist device (LVAD) implantation can be challenging in patients with a prior surgical ventricular restoration (SVR). In this case series of heart failure patients with a history of SVR, we describe the surgical technique and outcome of a customized approach for inflow cannula orientation. Seven patients with a history of SVR with end-stage chronic heart failure were accepted for long-term LVAD support. In all patients, the Dacron patch was removed through left ventriculotomy an... Abstract

Cited 39 times since 2016 (4.5 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 9, Issue 8, 1 1 2016, Pages e004357 Multicenter Experience With Catheter Ablation for Ventricular Tachycardia in Lamin A/C Cardiomyopathy. Kumar S, Androulakis AF, Sellal JM, Maury P, Gandjbakhch E, Waintraub X, Rollin A, Richard P, Charron P, Baldinger SH, Macintyre CJ, Koplan BA, John RM, Michaud GF, Zeppenfeld K, Sacher F, Lakdawala NK, Stevenson WG, Tedrow UB

Background: Lamin A/C (LMNA) cardiomyopathy is a genetic disease with a proclivity for ventricular arrhythmias. We describe the multicenter experience with percutaneous catheter ablation of sustained monomorphic ventricular tachycardia (VT) in LMNA cardiomyopathy. Methods and results: Twenty-five consecutive LMNA mutation patients from 4 centers were included (mean age, 55±9 years; ejection fraction, 34±12%; VT storm in 36%). Complete atrioventricular block was present in 11 patients; 3 patients... Abstract

Cited 12 times since 2016 (1.4 per year) source: EuropePMC

Journal of hypertension, Volume 34, Issue 8, 1 1 2016, Pages 1544-1550 Visit-to-visit blood pressure variability and future functional decline in old age. Ogliari G, Smit RA, Westendorp RG, Jukema JW, de Craen AJ, Sabayan B

Objective: Higher blood pressure variability (BPV), independent of mean blood pressure (BP), has been associated with adverse health outcomes. We investigated the association between visit-to-visit BPV and functional decline in older adults at high cardiovascular risk. Methods: In PROspective Study of Pravastatin in the Elderly at Risk, 4745 participants with mean age of 75.2 years and high cardiovascular risk were followed for a mean of 3.2 years. BP was measured in every 3 months during the fi... Abstract

Cited 83 times since 2016 (9.6 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 68, Issue 9, 1 1 2016, Pages 934-945 Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. van der Laan SW, Fall T, Soumaré A, Teumer A, Sedaghat S, Baumert J, Zabaneh D, van Setten J, Isgum I, Galesloot TE, Arpegård J, Amouyel P, Trompet S, Waldenberger M, Dörr M, Magnusson PK, Giedraitis V, Larsson A, Morris AP, Felix JF, Morrison AC, Franceschini N, Bis JC, Kavousi M, O'Donnell C, Drenos F, Tragante V, Munroe PB, Malik R, Dichgans M, Worrall BB, Erdmann J, Nelson CP, Samani NJ, Schunkert H, Marchini J, Patel RS, Hingorani AD, Lind L, Pedersen NL, de Graaf J, Kiemeney LA, Baumeister SE, Franco OH, Hofman A, Uitterlinden AG, Koenig W, Meisinger C, Peters A, Thorand B, Jukema JW, Eriksen BO, Toft I, Wilsgaard T, Onland-Moret NC, van der Schouw YT, Debette S, Kumari M, Svensson P, van der Harst P, Kivimaki M, Keating BJ, Sattar N, Dehghan A, Reiner AP, Ingelsson E, den Ruijter HM, de Bakker PI, Pasterkamp G, Ärnlöv J, Holmes MV, Asselbergs FW

Background: Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of creatinine-based renal function measurements. It is unclear whether this relationship is causal, arises from residual confounding, and/or is a consequence of reverse causation. Objectives: The aim of this study was to use Mendelian randomization to investigate whether cystatin C is causally related to CVD in the general population. Methods: We incorpor... Abstract

Cited 7 times since 2016 (0.8 per year) source: EuropePMC

The American journal of cardiology, Volume 118, Issue 8, 29 5 2016, Pages 1217-1224 Long-Term Echocardiographic Outcome in Super-Responders to Cardiac Resynchronization Therapy and the Association With Mortality and Defibrillator Therapy. van der Heijden AC, Höke U, Thijssen J, Willem Borleffs CJ, Wolterbeek R, Schalij MJ, van Erven L

Super-response to cardiac resynchronization therapy (CRT) is associated with significant left ventricular (LV) reverse remodeling and improved clinical outcome. The study aimed to: (1) evaluate whether LV reverse remodeling remains sustained during long-term follow-up in super-responders and (2) analyze the association between the course of LV reverse remodeling and ventricular arrhythmias. Of all, primary prevention super-responders to CRT were selected. Super-response was defined as LV end-sys... Abstract

Cited 3 times since 2016 (0.3 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 23, Issue 6, 29 5 2016, Pages 1399-1410 Diagnostic and prognostic roles of echocardiography and cardiac magnetic resonance. Delgado V, Bucciarelli-Ducci C, Bax JJ

Accurate prediction of sudden cardiac death due to ventricular arrhythmia remains challenging. Left ventricular ejection fraction has shown an association with increased risk of ventricular arrhythmias and is included in the recommendations for implantable cardioverter defibrillator as primary prevention. However, left ventricular ejection fraction may be normal in a large number of patients who are at risk of ventricular arrhythmias. Echocardiography remains the imaging technique of first choic... Abstract

Cited 29 times since 2016 (3.4 per year) source: EuropePMC

Scientific reports, Volume 6, 27 4 2016, Pages 30439 Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model. Wong C, Bezhaeva T, Rothuizen TC, Metselaar JM, de Vries MR, Verbeek FP, Vahrmeijer AL, Wezel A, van Zonneveld AJ, Rabelink TJ, Quax PH, Rotmans JI

Arteriovenous fistulas (AVF) for hemodialysis access have a 1-year primary patency rate of only 60%, mainly as a result of maturation failure that is caused by insufficient outward remodeling and intimal hyperplasia. The exact pathophysiology remains unknown, but the inflammatory vascular response is thought to play an important role. In the present study we demonstrate that targeted liposomal delivery of prednisolone increases outward remodeling of the AVF in a murine model. Liposomes accumulat... Abstract

Cited 18 times since 2016 (2.1 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 102, Issue 6, 22 4 2016, Pages 1981-1987 Effect of Aortic Valve Replacement on Aortic Root Dilatation Rate in Patients With Bicuspid and Tricuspid Aortic Valves. Regeer MV, Versteegh MI, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V

Background: It remains unclear whether aortic valve replacement (AVR) has an effect on the aortic root dilatation rate in patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV). The present study evaluated the pre- and postoperative annual aortic root dilatation rates in BAV and TAV. Methods: A total of 93 patients (67 ± 11 years; 71% men) who underwent AVR between 2003 and 2013 and had at least 2 pre- and postoperative echocardiographic studies 1 year or more apart were incl... Abstract

Cited 2 times since 2016 (0.2 per year) source: EuropePMC

Nuklearmedizin. Nuclear medicine, Volume 55, Issue 5, 20 3 2016, Pages 196-202 Sex differences in absolute myocardial perfusion. Non-invasive H2(15)O-PET in young healthy adults. Range FT, Kies P, Schäfers KP, Breithardt G, Schober O, Wichter T, Schäfers MA

Aim: To investigate sex differences in myocardial perfusion especially in healthy individuals since former studies are rare and findings are controversial. Participants, methods: 26 subjects were enrolled: 16 healthy women (age: 34 ±7 years) were compared with 10 healthy men (age: 34 ± 3 years; p = ns). Myocardial blood flow (MBF) and coronary vascular resistance (CVR) were quantified at rest, during adenosine infusion and cold-pressor-testing, using positron emission tomography and radioactive-... Abstract

Cited 13 times since 2016 (1.5 per year) source: EuropePMC

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 29, Issue 9, 19 3 2016, Pages 871-878 Prevalence and Correlates of Early Right Ventricular Dysfunction in Sarcoidosis and Its Association with Outcome. Joyce E, Kamperidis V, Ninaber MK, Katsanos S, Debonnaire P, Schalij MJ, Taube C, Bax JJ, Delgado V, Ajmone Marsan N

Background: Right ventricular (RV) function has not been systematically assessed in sarcoidosis. The aim of this study was to assess the prevalence and associates of RV dysfunction in sarcoidosis using global longitudinal peak systolic strain (GLS). Furthermore, whether RV dysfunction was associated with clinical outcomes was investigated. Methods: A total of 88 patients with sarcoidosis (mean age, 54 ± 13 years; 51% men) without known sarcoid-related or other structural heart disease or alterna... Abstract

Cited 5 times since 2016 (0.6 per year) source: EuropePMC

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 50, Issue 3, 19 3 2016, Pages 476-481 Valve-sparing root replacement in children. Kluin J, Koolbergen DR, Sojak V, Hazekamp MG

Objectives: In children, words of caution have been raised about valve-sparing procedures especially regarding the valve-remodelling technique. This study reviewed our experience with the valve-sparing reimplantation technique in children. Methods: All consecutive paediatric ( Abstract