8684 results
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 60, Issue 4, 10 2 2020, Pages 632-633
Imaging Assessment of Carotid Artery Stenosis Varies in Clinical Practice.
Brouwers JJWM, Versluijs Y, van Walderveen MAA, Hamming JF, Schepers A
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
International journal of environmental research and public health,
Volume 17, Issue 16, 7 1 2020, Pages E5707
Automatic Process Comparison for Subpopulations: Application in Cancer Care.
Marazza F, Bukhsh FA, Geerdink J, Vijlbrief O, Pathak S, Keulen MV, Seifert C
Processes in organisations, such as hospitals, may deviate from the intended standard processes, due to unforeseeable events and the complexity of the organisation. For hospitals, the knowledge of actual patient streams for patient populations (e.g., severe or non-severe cases) is important for quality control and improvement. Process discovery from event data in electronic health records can shed light on the patient flows, but their comparison for different populations is cumbersome and time-c...
Abstract
Cited 8 times since 2020 (1.7 per year)
source: EuropePMC
European journal of medical genetics,
Volume 63, Issue 11, 7 1 2020, Pages 104032
Glutaric aciduria type 1: Genetic and phenotypic spectrum in 53 patients.
Gürbüz BB, Yılmaz DY, Coşkun T, Tokatlı A, Dursun A, Sivri HS
Introduction: Glutaric aciduria type 1 (GA1) is a rare and inherited autosomal-recessive metabolic disorder that occurs in the deficiency of glutaryl-co-enzyme A dehydrogenase (GCDH) enzyme encoded by GCDH gene. In this study, we aim to retrospectively investigate the clinical, biochemical, and neuroradiological parameters and examine the spectrum of GCDH gene variants in Turkish patients with glutaric aciduria type 1. Methods: This is a descriptive cross-sectional study. The study was conducted...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Clinical case reports,
Volume 8, Issue 11, 6 1 2020, Pages 2320-2321
The constrictive consequences of pericardial calcifications.
Egorova AD, Schalij MJ, Kiès P
A 53-year-old man presented with symptomatic severe pulmonary valve regurgitation. He underwent a diagnostic catheterization. A heavily calcified pericardium and the pressure tracings illustrate typical features of constrictive pericarditis physiology, including the "square root sign." This condition is important to recognize given the progressive nature and poor prognosis if untreated.
Abstract
Cited 17 times since 2020 (3.5 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 25, Issue 3, 5 1 2020, Pages 230-237
Placebo effect in chronic inflammatory demyelinating polyneuropathy: The PATH study and a systematic review.
Lewis RA, Cornblath DR, Hartung HP, Sobue G, Lawo JP, Mielke O, Durn BL, Bril V, Merkies ISJ, Bassett P, Cleasby A, van Schaik IN, PATH study group
The Polyneuropathy And Treatment with Hizentra (PATH) study required subjects with chronic inflammatory demyelinating polyneuropathy (CIDP) to show dependency on immunoglobulin G (IgG) and then be restabilized on IgG before being randomized to placebo or one of two doses of subcutaneous immunoglobulin (SCIG). Nineteen of the 51 subjects (37%) randomized to placebo did not relapse over the next 24 weeks. This article explores the reasons for this effect. A post-hoc analysis of the PATH placebo gr...
Abstract
Cited 85 times since 2020 (17.6 per year)
source: EuropePMC
Cancer immunology research,
Volume 8, Issue 10, 5 1 2020, Pages 1311-1321
CD39 Identifies the CD4<sup>+</sup> Tumor-Specific T-cell Population in Human Cancer.
Kortekaas KE, Santegoets SJ, Sturm G, Ehsan I, van Egmond SL, Finotello F, Trajanoski Z, Welters MJP, van Poelgeest MIE, van der Burg SH
The accumulation of tumor-specific CD4+ and CD8+ effector T cells is key to an effective antitumor response. Locally, CD4+ T cells promote the recruitment and effector function of tumor-specific CD8+ T cells and activate innate killer cells in the tumor. Here, we show that tumor-specific CD4+ T cells were predominantly present in the CD39+ subset of tumor-infiltrating lymphocytes (TIL). The CD39+ CD4+ and CD8+ TILs were detected in three different tumor types, and displayed an activated (PD-1+,...
Abstract
BMC medical education,
Volume 20, Issue 1, 5 1 2020, Pages 250
Refuting misconceptions in medical physiology.
Versteeg M, van Loon MH, Wijnen-Meijer M, Steendijk P
Background: In medical physiology, educators and students face a serious challenge termed misconceptions. Misconceptions are incorrect ideas that do not match current scientific views. Accordingly, they have shown to hamper teaching and learning of physiological concepts. Conceptual Change Theory forms the basis of new teaching and learning practices that may alleviate misconceptions and facilitate critical thinking skills that are essential in becoming knowledgeable, self-regulated health profe...
Abstract
Cited 22 times since 2020 (4.6 per year)
source: EuropePMC
Molecular ecology resources,
Volume 20, Issue 6, 4 1 2020, Pages 1706-1722
A GT-seq panel for walleye (Sander vitreus) provides important insights for efficient development and implementation of amplicon panels in non-model organisms.
Bootsma ML, Gruenthal KM, McKinney GJ, Simmons L, Miller L, Sass GG, Larson WA
Targeted amplicon sequencing methods, such as genotyping-in-thousands by sequencing (GT-seq), facilitate rapid, accurate, and cost-effective analysis of hundreds of genetic loci in thousands of individuals. Development of GT-seq panels is nontrivial, but studies describing trade-offs associated with different steps of GT-seq panel development are rare. Here, we construct a dual-purpose GT-seq panel for walleye (Sander vitreus), discuss trade-offs associated with different development and genotyp...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 28, Issue 5, 4 1 2020, Pages 2343-2345
Hybrid Positron emission tomography/magnetic resonance imaging in viability assessment.
Bax JJ, Ng ACT, Delgado V
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 28, Issue Suppl 1, 1 1 2020, Pages 115-121
The role of long-term mechanical circulatory support in patients with advanced heart failure.
Felix SEA, de Jonge N, Caliskan K, Birim O, Damman K, Kuijpers M, Tops LF, Palmen M, Ramjankhan FZ
In patients with end-stage heart failure, advanced therapies such as heart transplantation and long-term mechanical circulatory support (MCS) with a left ventricular assist device (LVAD) have to be considered. LVADs can be implanted as a bridge to transplantation or as an alternative to heart transplantation: destination therapy. In the Netherlands, long-term LVAD therapy is gaining importance as a result of increased prevalence of heart failure together with a low number of heart transplantatio...
Abstract
Cited 32 times since 2020 (6.6 per year)
source: EuropePMC
Lab on a chip,
Volume 20, Issue 17, 1 1 2020, Pages 3132-3143
Multiplexed blood-brain barrier organ-on-chip.
Zakharova M, Palma do Carmo MA, van der Helm MW, Le-The H, de Graaf MNS, Orlova V, van den Berg A, van der Meer AD, Broersen K, Segerink LI
Organ-on-chip devices are intensively studied in academia and industry due to their high potential in pharmaceutical and biomedical applications. However, most of the existing organ-on-chip models focus on proof of concept of individual functional units without the possibility of testing multiple experimental stimuli in parallel. Here we developed a polydimethylsiloxane (PDMS) multiplexed chip with eight parallel channels branching from a common access port through which all eight channels can b...
Abstract
Cited 7 times since 2020 (1.4 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 8, 1 1 2020, Pages 828-832
EACVI survey on the evaluation of infective endocarditis.
Holte E, Dweck MR, Marsan NA, D'Andrea A, Manka R, Stankovic I, Haugaa KH
Aims: To evaluate the diagnosis and imaging of patients with suspected endocarditis and the management in routine clinical practice across Europe, the EACVI Scientific Initiatives Committee performed a survey across European centres. In particular, the routine use of echocardiography, advanced imaging modalities and multidisciplinary team was explored. Methods and results: A total of 100 European Echocardiography Laboratories from 29 different countries responded to the survey, which consisted o...
Abstract
Cited 8 times since 2020 (1.7 per year)
source: EuropePMC
European journal of emergency medicine : official journal of the European Society for Emergency Medicine,
Volume 27, Issue 4, 1 1 2020, Pages 243-244
The new era of chest pain evaluation in the Netherlands.
Backus BE, Tolsma RT, Boogers MJ
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Cardiovascular research,
Volume 116, Issue 10, 1 1 2020, Pages e115-e117
Gender balance at the heart of science.
Small HY, Timoteo AT, Buchanan GL, Gimelli A, Jurcut R, Marsan NA, Schüpke S, Zuhlke L
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 30, 1 1 2020, Pages 2828-2829
EHRA 2020 during COVID-19 days.
Burri H, Zeppenfeld K, Heidbuchel H
Abstract
Cited 8 times since 2020 (1.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 8, 1 1 2020, Pages 937-938
Echocardiography-computed tomography fusion imaging for guidance of transcatheter tricuspid valve annuloplasty.
Fortuni F, Marques AI, Bax JJ, Ajmone Marsan N, Delgado V
Abstract
Cited 5 times since 2020 (1 per year)
source: EuropePMC
Journal of neurology,
Volume 268, Issue 1, 31 5 2020, Pages 133-139
Presentation outside office hours does not negatively influence treatment times for reperfusion therapy for acute ischemic stroke.
Groot AE, de Bruin H, Nguyen TTM, Kappelhof M, de Beer F, Visser MC, Zwetsloot CP, Halkes PHA, de Kruijk J, van der Meulen WDM, van der Ree TC, Kwa VIH, van Schaik SM, Hani L, van den Berg R, Sprengers MES, Roosendaal SD, Emmer BJ, Nederkoorn PJ, Majoie CBLM, Roos YBWEM, Coutinho JM
Background: Treatment outside office hours has been associated with increased workflow times for intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). Limited data suggest that this "off-hours effect" also exists for endovascular treatment (EVT). We investigated this phenomenon in a well-organized acute stroke care region in the Netherlands. Methods: Retrospective, observational cohort study of consecutive patients with AIS who received reperfusion therapy in the Greater Amste...
Abstract
Cited 15 times since 2020 (3.1 per year)
source: EuropePMC
Journal of dairy science,
Volume 103, Issue 10, 31 5 2020, Pages 9446-9463
Quantification of risk factors for bovine viral diarrhea virus in cattle herds: A systematic search and meta-analysis of observational studies.
van Roon AM, Mercat M, van Schaik G, Nielen M, Graham DA, More SJ, Guelbenzu-Gonzalo M, Fourichon C, Madouasse A, Santman-Berends IMGA
Bovine viral diarrhea virus (BVDV) is endemic in many parts of the world, and multiple countries have implemented surveillance activities for disease control or eradication. In such control programs, the disease-free status can be compromised by factors that pose risks for introduction or persistence of the virus. The aim of the present study was to gain a comprehensive overview of possible risk factors for BVDV infection in cattle herds in Europe and to assess their importance. Papers that cons...
Abstract
Cited 6 times since 2020 (1.2 per year)
source: EuropePMC
Diabetologia,
Volume 63, Issue 11, 31 5 2020, Pages 2452-2461
A personalised screening strategy for diabetic retinopathy: a cost-effectiveness perspective.
Emamipour S, van der Heijden AAWA, Nijpels G, Elders P, Beulens JWJ, Postma MJ, van Boven JFM, Feenstra TL
Aims/hypothesis: In this study we examined the cost-effectiveness of three different screening strategies for diabetic retinopathy: using a personalised adaptive model, annual screening (fixed intervals), and the current Dutch guideline (stratified based on previous retinopathy grade). Methods: For each individual, optimal diabetic retinopathy screening intervals were determined, using a validated risk prediction model. Observational data (1998-2017) from the Hoorn Diabetes Care System cohort of...
Abstract
Cited 21 times since 2020 (4.3 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 6, Issue 9, 29 5 2020, Pages 1103-1114
Prevalence and Prognostic Impact of Pathogenic Variants in Patients With Dilated Cardiomyopathy Referred for Ventricular Tachycardia Ablation.
Ebert M, Wijnmaalen AP, de Riva M, Trines SA, Androulakis AFA, Glashan CA, Schalij MJ, Peter van Tintelen J, Jongbloed JDH, Zeppenfeld K
Objectives: This study aimed to assess the frequency of (likely) pathogenic variants (LP/Pv) among dilated cardiomyopathy (DCM) ventricular tachycardia (VT) patients referred for CA and their impact on procedural outcome and long-term prognosis. Background: The prevalence of genetic variants associated with monomorphic VT among DCM is unknown. Methods: Ninety-eight consecutive patients (age 56 ± 15 years; 84% men, left ventricular ejection fraction [LVEF] 39 ± 12%) referred for DCM-VT ablation w...
Abstract
