Publications
Below you can find a list of our published research.
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Below you can find a list of our published research.
7971 results
Cited 34 times since 2019 (5.7 per year) source: EuropePMC
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, Volume 24, Issue 25, 1 1 2019 Monitoring antimicrobial resistance trends in commensal <i>Escherichia coli</i> from livestock, the Netherlands, 1998 to 2016. Hesp A, Veldman K, van der Goot J, Mevius D, van Schaik G
BackgroundMonitoring of antimicrobial resistance (AMR) in animals is essential for public health surveillance. To enhance interpretation of monitoring data, evaluation and optimisation of AMR trend analysis is needed.AimsTo quantify and evaluate trends in AMR in commensal Escherichia coli, using data from the Dutch national AMR monitoring programme in livestock (1998-2016).MethodsFaecal samples were collected at slaughter from broilers, pigs and veal calves. Minimum inhibitory concentration valu... Abstract
Cited 17 times since 2019 (2.8 per year) source: EuropePMC
Simulation in healthcare : journal of the Society for Simulation in Healthcare, Volume 14, Issue 3, 1 1 2019, Pages 140-145 Self-Reported Emotions in Simulation-Based Learning: Active Participants vs. Observers. Rogers T, Andler C, OʼBrien B, van Schaik S
Introduction: Experiential learning through active participation is thought to be a key benefit of simulation-based education. Recent research has challenged this assumption, suggesting that active participants learn just as well as observers. Studies report that active participants experience stress and anxiety during simulation, which may hamper learning by active participants. We undertook the current study to examine whether active participation results in different emotional arousal than ob... Abstract
Cited 10 times since 2019 (1.7 per year) source: EuropePMC
Campbell systematic reviews, Volume 15, Issue 1-2, 1 1 2019, Pages e1014 PROTOCOL: School-based education programmes for improving knowledge of back health, ergonomics and postural behaviour of school children aged 4-18: A systematic review. Bettany-Saltikov J, McSherry R, van Schaik P, Kandasamy G, Hogg J, Whittaker V, Racero GA, Arnell T
Cited 48 times since 2019 (8 per year) source: EuropePMC
Pharmacogenomics, Volume 20, Issue 9, 1 1 2019, Pages 643-657 Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey. Karas Kuželički N, Prodan Žitnik I, Gurwitz D, Llerena A, Cascorbi I, Siest S, Simmaco M, Ansari M, Pazzagli M, Di Resta C, Brandslund I, Schwab M, Vermeersch P, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Stingl JC, van Schaik RH, Manolopoulos VG, Marc J, Pharmacogenomics Education Working Group (PGxEWG), European Society of Pharmacogenomics and Personalized Therapy (ESPT)
Aim: The need for pharmacogenomic education is becoming more and more urgent. Our aim was to evaluate the progress in pharmacogenomics education since then, and to put forward further recommendations. Methods: A survey was sent to 248 schools of medicine, pharmacy, nursing and health professions around the world. Results: The majority of the study programs (87%) include pharmacogenomics education, which is generally taught as part of the pharmacology curriculum. On average, educators and teacher... Abstract
Cited 10 times since 2019 (1.7 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 20, Issue 6, 1 1 2019, Pages 694-699 Left ventricular 2D speckle tracking echocardiography for detection of systolic dysfunction in genetic, dilated cardiomyopathies. van der Bijl P, Bootsma M, Hiemstra YL, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Genetic, dilated cardiomyopathy (DCM) can be caused by a large variety of mutations. Mutation carriers are often asymptomatic until DCM is well established, presenting with heart failure, arrhythmias, or sudden cardiac death. Preventive strategies can only be applied if DCM can be detected early. Echocardiographic, left ventricular (LV) global longitudinal strain (GLS) is a promising tool for early diagnosis, i.e. before a decrease in LV ejection fraction (EF) has occurred. We, therefore,... Abstract
Cited 5 times since 2019 (0.8 per year) source: EuropePMC
Campbell systematic reviews, Volume 15, Issue 1-2, 1 1 2019, Pages e1015 PROTOCOL: Evidence-informed practice versus evidence-based practice educational interventions for improving knowledge, attitudes, understanding, and behavior toward the application of evidence into practice: A comprehensive systematic review of undergraduate students. Kumah EA, McSherry R, Bettany-Saltikov J, Hamilton S, Hogg J, Whittaker V, van Schaik P
Cited 61 times since 2019 (10.2 per year) source: EuropePMC
Nature reviews. Cardiology, Volume 16, Issue 6, 1 1 2019, Pages 325-343 T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword. Simons KH, de Jong A, Jukema JW, de Vries MR, Arens R, Quax PHA
The role of inflammation in cardiovascular disease (CVD) is now widely accepted. Immune cells, including T cells, are influenced by inflammatory signals and contribute to the onset and progression of CVD. T cell activation is modulated by T cell co-stimulation and co-inhibition pathways. Immune checkpoint inhibitors (ICIs) targeting T cell inhibition pathways have revolutionized cancer treatment and improved survival in patients with cancer. However, ICIs might induce cardiovascular toxicity via... Abstract
Cited 131 times since 2019 (21.8 per year) source: EuropePMC
European heart journal, Volume 40, Issue 22, 1 1 2019, Pages 1756-1763 Cardio-Oncology Services: rationale, organization, and implementation. Lancellotti P, Suter TM, López-Fernández T, Galderisi M, Lyon AR, Van der Meer P, Cohen Solal A, Zamorano JL, Jerusalem G, Moonen M, Aboyans V, Bax JJ, Asteggiano R
Aims: Anticancer therapies have extended the lives of millions of patients with malignancies, but for some this benefit is tempered by adverse cardiovascular (CV) effects. Cardiotoxicity may occur early or late after treatment initiation or termination. The extent of this cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, mediastinal radiotherapy, the presence of CV risk factors, and comorbidities. A recent position paper from the European Society of Ca... Abstract
Cited 54 times since 2019 (9 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 12, Issue 6, 1 1 2019, Pages 1058-1072 The Future of Cardiovascular Computed Tomography: Advanced Analytics and Clinical Insights. Nicol ED, Norgaard BL, Blanke P, Ahmadi A, Weir-McCall J, Horvat PM, Han K, Bax JJ, Leipsic J
Cardiovascular computed tomography (CCT) has undergone rapid maturation over the last decade and is now of proven clinical utility in the diagnosis and management of coronary artery disease, in guiding structural heart disease intervention, and in the diagnosis and treatment of congenital heart disease. The next decade will undoubtedly witness further advances in hardware and advanced analytics that will potentially see an increasingly core role for CCT at the center of clinical cardiovascular p... Abstract
Cited 7 times since 2019 (1.2 per year) source: EuropePMC
European heart journal, Volume 40, Issue 21, 1 1 2019, Pages 1728-1738 Roadmap for cardiovascular education across the European Society of Cardiology: inspiring better knowledge and skills, now and for the future. Kotecha D, Bax JJ, Carrera C, Casadei B, Merkely B, Anker SD, Vardas PE, Kearney PP, Roffi M, Ros M, Vahanian A, Weidinger F, Beeri R, Budaj A, Calabrò P, Czerwińska-Jelonkiewicz K, D'Ascenzi F, De Potter T, Fox KF, Hartikainen J, McAdam B, Milicic D, Pasquet AA, Sionis A, Sohaib SMA, Tsioufis C, Verhorst PMJ, Kirchhof P, ESC Scientific Document Group, 2016 ESC Education Conference
Aims: The provision of high-quality education allows the European Society of Cardiology (ESC) to achieve its mission of better cardiovascular practice and provides an essential component of translating new evidence to improve outcomes. Methods and results: The 4th ESC Education Conference, held in Sophia Antipolis (December 2016), brought together ESC education leaders, National Directors of Training of 43 ESC countries, and representatives of the ESC Young Community. Integrating national descri... Abstract
Cited 88 times since 2019 (14.6 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 20, Issue 6, 1 1 2019, Pages 620-624 MITRA-FR vs. COAPT: lessons from two trials with diametrically opposed results. Pibarot P, Delgado V, Bax JJ
Percutaneous mitral valve repair using the MitraClip device has been proposed to correct secondary mitral regurgitation (MR). Recently, the results of two randomized controlled trials, that is MITRA-FR (Percutaneous Repair with the MitraClip Device for Severe Functional/Secondary Mitral Regurgitation) and COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation), assessing the efficacy and safety of MitraClip... Abstract
Cited 212 times since 2019 (35.3 per year) source: EuropePMC
European heart journal, Volume 40, Issue 24, 1 1 2019, Pages 1975-1986 Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging. Al'Aref SJ, Anchouche K, Singh G, Slomka PJ, Kolli KK, Kumar A, Pandey M, Maliakal G, van Rosendael AR, Beecy AN, Berman DS, Leipsic J, Nieman K, Andreini D, Pontone G, Schoepf UJ, Shaw LJ, Chang HJ, Narula J, Bax JJ, Guan Y, Min JK
Artificial intelligence (AI) has transformed key aspects of human life. Machine learning (ML), which is a subset of AI wherein machines autonomously acquire information by extracting patterns from large databases, has been increasingly used within the medical community, and specifically within the domain of cardiovascular diseases. In this review, we present a brief overview of ML methodologies that are used for the construction of inferential and predictive data-driven models. We highlight seve... Abstract
European heart journal, Volume 40, Issue 22, 1 1 2019, Pages 1749-1751 What was hot at the EHRA2019 Congress. Burri H, Zeppenfeld K
Cited 52 times since 2019 (8.7 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 15, Issue 2, 1 1 2019, Pages 147-154 Optimising patient discharge management after transfemoral transcatheter aortic valve implantation: the multicentre European FAST-TAVI trial. Barbanti M, van Mourik MS, Spence MS, Iacovelli F, Martinelli GL, Muir DF, Saia F, Bortone AS, Densem CG, van der Kley F, Bramlage P, Vis M, Tamburino C
Aims: Treatment pathway optimisation in TAVI should include timely patient discharge with a minimised risk for out-of-hospital adverse events. The aim of this study was to define a standardised set of risk criteria that allows a safe and timely discharge, to validate their appropriateness prospectively in different centres and multiple European countries, and to assess post-discharge outcomes. Methods and results: We defined and validated the adequacy of a set of discharge criteria and its abili... Abstract
Cited 10 times since 2019 (1.7 per year) source: Scopus
Behavioural processes, Volume 166, 30 5 2019, Pages 103877 Does socio-ecology drive differences in alertness between wolves and dogs when resting? Kortekaas K, Kotrschal K
Variation in resting behaviour across animals may be driven by adaptations towards their environment. Wolves and dogs seem promising models to examine this idea as they share a common ancestor, but occupy different socio-ecological niches. While wolves generally avoid humans, hunt, defend their territory, and raise offspring cooperatively, most dogs live in human-shaped environments. Hence, we hypothesized wolves to be more alert towards their environment than dogs, i.e. the degree of activation... Abstract
Cited 5 times since 2019 (0.8 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 24, Issue 2, 29 5 2019, Pages 174-179 Diagnosis and treatment response in the asymmetric variant of chronic inflammatory demyelinating polyneuropathy. Lucke IM, Wieske L, van der Kooi AJ, van Schaik IN, Eftimov F, Verhamme C
The objectives were to (a) assess the diagnostic value of testing clinically affected and unaffected limbs with nerve conduction studies (NCS) in patients with the asymmetric chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) variant and to define the most useful strategy for diagnosis, and (b) describe treatment response and long-term outcome. We performed a retrospective study and included patients with a multifocal distribution of symptoms and signs, who met the probable or defi... Abstract
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 95, Issue 4, 29 5 2019, Pages 686-693 Procedural-related coronary atrial branch occlusion during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction and atrial arrhythmias at follow-up. Montero Cabezas JM, Abou R, Goedemans L, Agüero J, Schalij MJ, Ajmone Marsan N, Fuster V, Ibáñez B, Bax JJ, Delgado V
Objectives: To evaluate the frequency of procedural-related atrial branch occlusion in ST-segment elevation myocardial infarction (STEMI) patients and its association with atrial arrhythmias at 1-year follow-up. Background: Atrial ischemia due to procedural-related coronary atrial branch occlusion in elective percutaneous coronary intervention (PCI) has been associated with atrial arrhythmias. Its role in a STEMI scenario is unknown. Methods: STEMI patients treated with primary PCI were classifi... Abstract
Cited 10 times since 2019 (1.7 per year) source: EuropePMC
Journal of vascular surgery, Volume 71, Issue 1, 27 4 2019, Pages 242-249 Using maximal systolic acceleration to diagnose and assess the severity of peripheral artery disease in a flow model study. Brouwers JJWM, van Doorn LP, van Wissen RC, Putter H, Hamming JF
Background: Because of the presence of medial calcific sclerosis, both ankle-branchial index and toe pressure measures can yield misleading results when attempting to diagnose peripheral artery disease (PAD). A new ultrasound parameter, maximal systolic acceleration (ACCmax), can be an accurate tool for diagnosing PAD, including in diabetic patients. However, it has not been evaluated thoroughly. The aim of this study was to assess the feasibility of using ACCmax to diagnose and assess the sever... Abstract
Cited 17 times since 2019 (2.8 per year) source: EuropePMC
The American journal of cardiology, Volume 124, Issue 4, 27 4 2019, Pages 604-612 Prevalence and Prognostic Implications of Right Ventricular Dysfunction in Patients With Hypertrophic Cardiomyopathy. Hiemstra YL, Debonnaire P, Bootsma M, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Right ventricular (RV) dysfunction is a well-known prognostic factor in several cardiac diseases. However, the prevalence of RV dysfunction in hypertrophic cardiomyopathy (HC) is unclear and its prognostic value is unknown. This study aims at addressing these issues assessing RV function with speckle tracking echocardiography. In 267 HC patients (52 ± 15 years, 68% male), standard and advanced echocardiographic measurements of RV function were performed including RV 4-chamber longitudinal strain... Abstract
Cited 46 times since 2019 (7.6 per year) source: EuropePMC
Viruses, Volume 11, Issue 5, 25 4 2019, Pages E478 Animals as Reservoir for Human Norovirus. Villabruna N, Koopmans MPG, de Graaf M
Norovirus is the most common cause of non-bacterial gastroenteritis and is a burden worldwide. The increasing norovirus diversity is currently categorized into at least 10 genogroups which are further classified into more than 40 genotypes. In addition to humans, norovirus can infect a broad range of hosts including livestock, pets, and wild animals, e.g., marine mammals and bats. Little is known about norovirus infections in most non-human hosts, but the close genetic relatedness between some a... Abstract