Publications
Below you can find a list of our published research.
Op korte termijn komt deze Hart Long Centrum website te vervallen. Alle informatie kunt u vanaf heden vinden op https://www.lumc.nl/patientenzorg/specialistische-centra/hart-long-centrum/voor-patienten/
Below you can find a list of our published research.
7971 results
Cited 17 times since 2019 (2.8 per year) source: EuropePMC
Cells, Volume 8, Issue 4, 9 2 2019, Pages E334 Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis. Kritikou E, Depuydt MAC, de Vries MR, Mulder KE, Govaert AM, Smit MD, van Duijn J, Foks AC, Wezel A, Smeets HJ, Slütter B, Quax PHA, Kuiper J, Bot I
The presence of mast cells in human atherosclerotic plaques has been associated with adverse cardiovascular events. Mast cell activation, through the classical antigen sensitized-IgE binding to their characteristic Fcε-receptor, causes the release of their cytoplasmic granules. These granules are filled with neutral proteases such as tryptase, but also with histamine and pro-inflammatory mediators. Mast cells accumulate in high numbers within human atherosclerotic tissue, particularly in the sho... Abstract
Cited 16 times since 2019 (2.6 per year) source: EuropePMC
Veterinary microbiology, Volume 232, 6 1 2019, Pages 58-64 Prevalence of extended-spectrum and AmpC β-lactamase-producing Escherichia coli in Dutch dairy herds. Heuvelink AE, Gonggrijp MA, Buter RGJ, Ter Bogt-Kappert CC, van Schaik G, Velthuis AGJ, Lam TJGM
This study was conducted to assess: (1) a change in between-herd prevalence of extended-spectrum and AmpC β-lactamase-producing Escherichia coli (ESBL/AmpC-EC) between 2011 and 2013, the period during which the antimicrobial policy in animal husbandry in the Netherlands changed significantly, and (2) the prevalence of ESBL/AmpC-EC in individual calves, young stock, and dairy cows in the Netherlands. In 196 randomly selected conventional dairy herds, faecal samples were collected from calves (max... Abstract
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 57, Issue 6, 3 1 2019, Pages 766 Saccular Aneurysm of the Brachiocephalic Vein. van der Vorst JR, Veger HTC
Cited 7 times since 2019 (1.1 per year) source: EuropePMC
Preventive veterinary medicine, Volume 168, 3 1 2019, Pages 1-8 Short-term effects of air pollution and temperature on cattle mortality in the Netherlands. Egberts V, van Schaik G, Brunekreef B, Hoek G
Background: Extreme temperatures and air pollution are both associated with increased mortality risk in humans. However, the effects of temperature and air pollution on cattle have not been investigated much before. Objectives: Short-term effects of temperature (heat and cold) and air pollution on cattle mortality were investigated and quantified in the Netherlands during 2012-2017. Methods: Daily data on cattle mortality, weather conditions and mean levels of particulate matter (PM10), ozone (O... Abstract
Cited 10 times since 2019 (1.6 per year) source: EuropePMC
BMC infectious diseases, Volume 19, Issue 1, 3 1 2019, Pages 303 Incidence and microbiology of post-operative infections after radical cystectomy and ureteral stent removal; a retrospective cohort study. Kolwijck E, Seegers AEM, Tops SCM, van der Heijden AG, Sedelaar JPM, Ten Oever J
Background: Post-operative infections are frequent after radical cystectomy with urinary diversion surgery (UDS). Reduction of post-operative infections necessitates appropriate peri-operative antimicrobial prophylaxis targeting causative bacteria. We assessed the incidence and microbiology of infections in the 30-day post-operative period after UDS and investigated effectiveness of the currently used peri-operative antibacterial prophylaxis. Methods: Retrospective cohort study of all patients u... Abstract
Cited 41 times since 2019 (6.6 per year) source: EuropePMC
Evolutionary anthropology, Volume 28, Issue 3, 2 1 2019, Pages 133-143 Evaluating the self-domestication hypothesis of human evolution. Sánchez-Villagra MR, van Schaik CP
"Self-domestication" has been invoked to understand important aspects of human evolution, integrating physiological, behavioral, and morphological information in a novel way. It proposes that selection for reduced aggression on animals undergoing domestication provides a model for selection favoring prosocial behaviors in humans and for a set of seemingly independent features, which arose as a result of developmental correlation. We review the history of the idea and examine patterns o... Abstract
Cited 9 times since 2019 (1.5 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 108, Issue 1, 2 1 2019, Pages 167-174 Multicenter Phase II Clinical Trial of Isolated Lung Perfusion in Patients With Lung Metastases. Beckers PAJ, Versteegh MIM, Van Brakel TJ, Braun J, Van Putte B, Maat APWM, Vergauwen W, Rodrigus I, Den Hengst W, Lardon F, De Bruijn E, Guetens G, De Boeck G, Gielis JF, Lauwers P, Denissen L, Hendriks JMH, Van Schil PE
Background: Up to 66% of patients show local pulmonary disease progression after pulmonary metastasectomy. Regional treatment with isolated lung perfusion (ILuP) may improve local control with minimal systemic adverse effects. The aims of this study were to evaluate local and distant control after ILuP, determine the effect on overall survival compared with historical controls, and confirm the safety and feasibility of ILuP. Methods: A total of 107 patients with resectable pulmonary metastases o... Abstract
Cited 2 times since 2019 (0.3 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 55, Issue 4, 1 1 2019, Pages 751-759 Beyond the clinical impact of aortic and pulmonary valve implantation: health-related quality of life, informal care and productivity†. Huygens SA, van der Kley F, Bekkers JA, Bogers AJJC, Takkenberg JJM, Rutten-van Mölken MPMH
Objectives: Our aim was to provide estimates of patient-reported health-related quality of life (HRQoL), use of informal care and productivity in patients after surgical aortic and pulmonary valve replacement and transcatheter aortic valve implantation. Methods: Consecutive cohorts of 1239 adult patients who had surgical aortic valve replacement or surgical pulmonary valve replacement and 433 patients who had transcatheter aortic valve implantation at 2 Dutch heart centres were cross-sectionally... Abstract
Cited 9 times since 2019 (1.5 per year) source: EuropePMC
Rheumatology (Oxford, England), Volume 58, Issue 4, 1 1 2019, Pages 730-732 Prognostic properties of anti-topoisomerase antibodies in patients identified by the ACR/EULAR 2013 systemic sclerosis criteria. Boonstra M, Ninaber MK, Ajmone Marsan N, Huizinga TWJ, Scherer HU, de Vries-Bouwstra JK
Cited 14 times since 2019 (2.3 per year) source: EuropePMC
Journal of cellular and molecular medicine, Volume 23, Issue 6, 1 1 2019, Pages 3888-3896 IRF3 and IRF7 mediate neovascularization via inflammatory cytokines. Simons KH, de Vries MR, de Jong RCM, Peters HAB, Jukema JW, Quax PHA
Objective: To elucidate the role of interferon regulatory factor (IRF)3 and IRF7 in neovascularization. Methods: Unilateral hind limb ischaemia was induced in Irf3-/- , Irf7-/- and C57BL/6 mice by ligation of the left common femoral artery. Post-ischaemic blood flow recovery in the paw was measured with laser Doppler perfusion imaging. Soleus, adductor and gastrocnemius muscles were harvested to investigate angiogenesis and arteriogenesis and inflammation. Results: Post-ischaemic blood flow reco... Abstract
Cited 17 times since 2019 (2.8 per year) source: EuropePMC
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Volume 41, 1 1 2019, Pages 29-37 The role of hemodynamics in bicuspid aortopathy: a histopathologic study. Grewal N, Girdauskas E, DeRuiter M, Goumans MJ, Poelmann RE, Klautz RJM, Gittenberger-de Groot AC
Background: A bicuspid aortic valve (BAV) is the most common congenital cardiac malformation and is associated with ascending aortic dilation in 60%-80% of patients. In this study, we aimed to address the role of hemodynamic influences on the development of aortopathy in BAV patients. Patient and methods: BAV (n=36) and tricuspid aortic valve (TAV) patients (n=17) undergoing aortic valve replacement underwent preoperative flow magnetic resonance imaging (MRI) assessment to detect the area of max... Abstract
Cited 23 times since 2019 (3.7 per year) source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Volume 34, Issue 4, 1 1 2019, Pages 650-659 Low thyroid function is not associated with an accelerated deterioration in renal function. Meuwese CL, van Diepen M, Cappola AR, Sarnak MJ, Shlipak MG, Bauer DC, Fried LP, Iacoviello M, Vaes B, Degryse J, Khaw KT, Luben RN, Åsvold BO, Bjøro T, Vatten LJ, de Craen AJM, Trompet S, Iervasi G, Molinaro S, Ceresini G, Ferrucci L, Dullaart RPF, Bakker SJL, Jukema JW, Kearney PM, Stott DJ, Peeters RP, Franco OH, Völzke H, Walsh JP, Bremner A, Sgarbi JA, Maciel RMB, Imaizumi M, Ohishi W, Dekker FW, Rodondi N, Gussekloo J, den Elzen WPJ, Thyroid Studies Collaboration
Background: Chronic kidney disease (CKD) is frequently accompanied by thyroid hormone dysfunction. It is currently unclear whether these alterations are the cause or consequence of CKD. This study aimed at studying the effect of thyroid hormone alterations on renal function in cross-sectional and longitudinal analyses in individuals from all adult age groups. Methods: Individual participant data (IPD) from 16 independent cohorts having measured thyroid stimulating hormone, free thyroxine levels... Abstract
Cited 15 times since 2019 (2.4 per year) source: EuropePMC
Toxicological sciences : an official journal of the Society of Toxicology, Volume 168, Issue 2, 1 1 2019, Pages 519-534 Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice. Pouwer MG, Pieterman EJ, Chang SC, Olsen GW, Caspers MPM, Verschuren L, Jukema JW, Princen HMG
Epidemiological studies have reported positive associations between serum perfluorooctanoic acid (PFOA) and total and non-high-density lipoprotein cholesterol (non-HDL-C) although the magnitude of effect of PFOA on cholesterol lacks consistency. The objectives of this study were to evaluate the effect of PFOA on plasma cholesterol and triglyceride metabolism at various plasma PFOA concentrations relevant to humans, and to elucidate the mechanisms using APOE*3-Leiden.CETP mice, a model with a hum... Abstract
Cited 50 times since 2019 (8.1 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 21, Issue 4, 1 1 2019, Pages 581-589 Cryoballoon vs. radiofrequency ablation for atrial fibrillation: a study of outcome and safety based on the ESC-EHRA atrial fibrillation ablation long-term registry and the Swedish catheter ablation registry. Mörtsell D, Arbelo E, Dagres N, Brugada J, Laroche C, Trines SA, Malmborg H, Höglund N, Tavazzi L, Pokushalov E, Stabile G, Blomström-Lundqvist C, ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry investigators
Aims: Pulmonary vein isolation (PVI), the standard for atrial fibrillation (AF) ablation, is most commonly applied with radiofrequency (RF) energy, although cryoballoon technology (CRYO) has gained widespread use. The aim was to compare the second-generation cryoballoon and the irrigated RF energy regarding outcomes and safety. Methods and results: Of 4657 patients undergoing their first AF ablation, 982 with CRYO and 3675 with RF energy were included from the Swedish catheter ablation registry... Abstract
Cited 8 times since 2019 (1.3 per year) source: EuropePMC
Journal of orthopaedic trauma, Volume 33, Issue 4, 1 1 2019, Pages e124-e130 Ultrasound-Guided Nerve Blocks as Analgesia for Nonoperative Management of Distal Radius Fractures-Two Consecutive Randomized Controlled Trials. Siebelt M, Hartholt KA, van Winden DFM, Boot F, Papathanasiou D, Verdouw BC, de Vries MR, Mathijssen NM, Kraan GA
Objectives: To investigate whether a conventional fracture hematoma block (FHB) or an ultrasound-guided peripheral nerve block has more superior analgesic effect during nonoperative management of distal radius fractures in an emergency department setting. Two peripheral nerve block types were investigated, one at the level of the elbow, or cubital nerve block (CNB), and another an axillary nerve block (ANB). Design: Two prospective randomized controlled studies were performed to compare the diff... Abstract
Cited 7 times since 2019 (1.1 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 30, Issue 6, 29 5 2019, Pages 902-909 Optimizing ablation duration using dormant conduction to reveal incomplete isolation with the second generation cryoballoon: A randomized controlled trial. Keçe F, de Riva M, Naruse Y, Alizadeh Dehnavi R, Wijnmaalen AP, Schalij MJ, Zeppenfeld K, Trines SA
Introduction: Efficacy of cryoballoon ablation depends on balloon-tissue contact and ablation duration. Prolonged duration may increase extracardiac complications. The aim of this study is to determine the optimal additional ablation duration after acute pulmonary vein isolation (PVI). Methods: Consecutive patients with paroxysmal AF were randomized to three groups according to additional ablation duration (90, 120, or 150 seconds) after acute PVI (time-to-isolation). Primary outcome was reconne... Abstract
Cited 11 times since 2019 (1.8 per year) source: EuropePMC
Nutrition, metabolism, and cardiovascular diseases : NMCD, Volume 29, Issue 7, 28 4 2019, Pages 728-735 The role of inflammation in the association between overall and visceral adiposity and subclinical atherosclerosis. Christen T, Trompet S, Rensen PCN, Willems van Dijk K, Lamb HJ, Jukema JW, Rosendaal FR, le Cessie S, de Mutsert R
Background and aims: Inflammation may underlie the association between obesity, atherosclerosis and cardiovascular disease. We investigated to what extent markers of inflammation mediate associations between overall and visceral body fat and subclinical atherosclerosis. Methods and results: In this cross-sectional analysis of the Netherlands Epidemiology of Obesity study we estimated total body fat (TBF) by bio-impedance analysis, carotid artery intima media thickness (cIMT) by ultrasound, C-rea... Abstract
Cancer investigation, Volume 37, Issue 3, 25 4 2019, Pages 156-162 Mannose binding lectin and prediction of risk for chemotherapy induced febrile neutropenia in patients with a solid tumor. Epskamp C, Goudzwaard JA, Fiets E, Zuetenhorst JM, Polee MB, van de Geijn GM, van Schaik RHN, Birnie E, Hamberg P
Mannose-binding lectin (MBL) - deficient patients who undergo chemotherapy for a solid tumor might have an increased risk developing febrile neutropenia (FN). We investigated in a prospective cohort study relations between MBL-serum levels and polymorphisms in MBL promotor genotypes (-550H/L and -221X/Y) on incidence and severity of FN. Risk of FN was 17.9% in MBL-deficient and 22.5% in MBL-sufficient patients (RR = 0.796, p = 0.45). Median MBL serum levels at baseline were respectively 1.39 µg/... Abstract
Cited 57 times since 2019 (9.2 per year) source: EuropePMC
Blood reviews, Volume 35, 25 4 2019, Pages 59-67 Atrial fibrillation and cancer - An unexplored field in cardiovascular oncology. Chu G, Versteeg HH, Verschoor AJ, Trines SA, Hemels MEW, Ay C, Huisman MV, Klok FA
An increasing body of evidence suggests an association between cancer and atrial fibrillation (AF). The exact magnitude and underlying mechanism of this association are however unclear. Cancer-related inflammation, anti-cancer treatment and other cancer-related comorbidities are proposed to affect atrial remodelling, increasing the susceptibility of cancer patients for developing AF. Moreover, cancer is assumed to modify the risk of thromboembolisms and bleeding. A thorough and adequate understa... Abstract
Cited 22 times since 2019 (3.5 per year) source: EuropePMC
Cancers, Volume 11, Issue 3, 22 4 2019, Pages E403 Impact of Curcumin (with or without Piperine) on the Pharmacokinetics of Tamoxifen. Hussaarts KGAM, Hurkmans DP, Oomen-de Hoop E, van Harten LJ, Berghuis S, van Alphen RJ, Spierings LEA, van Rossum-Schornagel QC, Vastbinder MB, van Schaik RHN, van Gelder T, Jager A, van Leeuwen RWF, Mathijssen RHJ
Tamoxifen is a prodrug that is primarily metabolized into the pharmacologically active metabolite endoxifen and eventually into inactive metabolites. The herb curcumin may increase endoxifen exposure by affecting phase II metabolism. We compared endoxifen and tamoxifen exposure in breast cancer patients with or without curcumin, and with addition of the bio-enhancer piperine. Tamoxifen (20⁻30mg per day (q.d.)) was either given alone, or combined with curcumin (1200 mg three times daily (t.i.d.))... Abstract