8684 results
Journal of the American College of Cardiology,
Volume 66, Issue 22, 1 1 2015, Pages 2576-2577
Reply: Elimination of All Inducible Ventricular Tachycardias as the Endpoint for Ablation.
Yokokawa M, Kim HM, Baser K, Stevenson W, Nagashima K, Della Bella P, Vergara P, Hindricks G, Arya A, Zeppenfeld K, de Riva Silva M, Daoud EG, Kumar S, Kuck KH, Tilz R, Mathew S, Ghanbari H, Latchamsetty R, Morady F, Bogun F
Abstract
Cited 31 times since 2015 (3.3 per year)
source: EuropePMC
American heart journal,
Volume 173, 1 1 2015, Pages 77-85
Rationale and design of POPular-TAVI: antiPlatelet therapy fOr Patients undergoing Transcatheter Aortic Valve Implantation.
Nijenhuis VJ, Bennaghmouch N, Hassell M, Baan J, van Kuijk JP, Agostoni P, van 't Hof A, Kievit PC, Veenstra L, van der Harst P, van den Heuvel AF, den Heijer P, Kelder JC, Deneer VH, van der Kley F, Onorati F, Collet JP, Maisano F, Latib A, Huber K, Stella PR, Ten Berg JM
Background: Despite improving experience and techniques, ischemic and bleeding complications after transcatheter aortic valve implantation (TAVI) remain prevalent and impair survival. Current guidelines recommend the temporary addition of clopidogrel in the initial period after TAVI to prevent thromboembolic events. However, explorative studies suggest that this is associated with a higher rate of major bleeding without a decrease in thromboembolic complications. Methods: The POPular TAVI trial...
Abstract
Cited 24 times since 2015 (2.5 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 27, Issue 1, 25 4 2015, Pages 80-87
VT Recurrence After Ablation: Incomplete Ablation or Disease Progression? A Multicentric European Study.
Berte B, Sacher F, Venlet J, Andreu D, Mahida S, Aldhoon B, DE Potter T, Sarkozy A, Tavernier R, Andronache M, Deneke T, Kautzner J, Berruezo A, Cochet H, Zeppenfeld K, Jaïs P
Aim: To determine whether ventricular tachycardia (VT) recurrences in arrhythmogenic RV cardiomyopathy (ARVC) and nonischemic cardiomyopathy (NICM) are related to incomplete ablation or disease progression. Methods: ARVC and NICM patients with two substrate maps of the same diseased ventricle with an interprocedural delay of ≥12 months were included. Disease progression was defined as ≥1 factor: scar area progression (PROG, +5%), ventricular remodeling (dilatation [+25 mL] or decreased ejection...
Abstract
European journal of preventive cardiology,
Volume 23, Issue 11, 24 4 2015, Pages 1195-1201
Advantages and disadvantages of unstructured cardiovascular risk factor screening for follow-up in primary care.
de Boer AW, de Mutsert R, den Heijer M, Rosendaal FR, Jukema JW, Blom JW, Numans ME, NEO study group
Background: In contrast to structured, integrated risk assessment in primary care, unstructured risk factor screening outside primary care and corresponding recommendations to consult a general practitioner (GP) are often based on one abnormal value of a single risk factor. This study investigates the advantages and disadvantages of unstructured screening of blood pressure and cholesterol outside primary care. Methods: After the baseline visit of the Netherlands Epidemiology of Obesity study (po...
Abstract
Cited 6 times since 2015 (0.6 per year)
source: EuropePMC
European journal of preventive cardiology,
Volume 23, Issue 10, 24 4 2015, Pages 1104-1113
Risk stratification and treatment effect of statins in secondary cardiovascular prevention in old age: Additive value of N-terminal pro-B-type natriuretic peptide.
Poortvliet RK, van Peet PG, de Craen AJ, Mertens BJ, Mooijaart SP, Wijsman LW, Drewes YM, Ford I, Sattar N, Jukema JW, Stott DJ, de Ruijter W, Gussekloo J
Background: To date, no validated risk scores exist for prediction of recurrence risk or potential treatment effect for older people with a history of a cardiovascular event. Therefore, we assessed predictive values for recurrent cardiovascular disease of models with age and sex, traditional cardiovascular risk markers, and 'SMART risk score', all with and without addition of N-terminal pro-B-type natriuretic peptide (NT-proBNP). Treatment effect of pravastatin was assessed across low...
Abstract
Cited 8 times since 2015 (0.8 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 102, Issue 2, 23 4 2015, Pages 107-113
Aortic valve prosthesis-patient mismatch and exercise capacity in adult patients with congenital heart disease.
van Slooten YJ, van Melle JP, Freling HG, Bouma BJ, van Dijk AP, Jongbloed MR, Post MC, Sieswerda GT, Huis In 't Veld A, Ebels T, Voors AA, Pieper PG
Objectives: To report the prevalence of aortic valve prosthesis-patient mismatch (PPM) in an adult population with congenital heart disease (CHD) and its impact on exercise capacity. Adults with congenital heart disease (ACHD) with a history of aortic valve replacement may outgrow their prosthesis later in life. However, the prevalence and clinical consequences of aortic PPM in ACHD are presently unknown. Methods: From the national Dutch Congenital Corvitia (CONCOR) registry, we identified 207 A...
Abstract
Cited 8 times since 2015 (0.8 per year)
source: EuropePMC
Muscle & nerve,
Volume 53, Issue 1, 21 3 2015, Pages 127-133
Assessment of intensive care unit-acquired weakness in young and old mice: An E. coli septic peritonitis model.
Witteveen E, Hoogland IC, Wieske L, Weber NC, Verhamme C, Schultz MJ, van Schaik IN, Horn J
Introduction: There are few reports of in vivo muscle strength measurements in animal models of ICU-acquired weakness (ICU-AW). In this study we investigated whether the Escherichia coli (E. coli) septic peritonitis mouse model may serve as an ICU-AW model using in vivo strength measurements and myosin/actin assays, and whether development of ICU-AW is age-dependent in this model. Methods: Young and old mice were injected intraperitoneally with E. coli and treated with ceftriaxone. Forelimb grip...
Abstract
Cited 98 times since 2015 (10.3 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 99, Issue 2, 20 3 2015, Pages 172-185
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
Kalman LV, Agúndez J, Appell ML, Black JL, Bell GC, Boukouvala S, Bruckner C, Bruford E, Caudle K, Coulthard SA, Daly AK, Del Tredici A, den Dunnen JT, Drozda K, Everts RE, Flockhart D, Freimuth RR, Gaedigk A, Hachad H, Hartshorne T, Ingelman-Sundberg M, Klein TE, Lauschke VM, Maglott DR, McLeod HL, McMillin GA, Meyer UA, Müller DJ, Nickerson DA, Oetting WS, Pacanowski M, Pratt VM, Relling MV, Roberts A, Rubinstein WS, Sangkuhl K, Schwab M, Scott SA, Sim SC, Thirumaran RK, Toji LH, Tyndale RF, van Schaik R, Whirl-Carrillo M, Yeo K, Zanger UM
This article provides nomenclature recommendations developed by an international workgroup to increase transparency and standardization of pharmacogenetic (PGx) result reporting. Presently, sequence variants identified by PGx tests are described using different nomenclature systems. In addition, PGx analysis may detect different sets of variants for each gene, which can affect interpretation of results. This practice has caused confusion and may thereby impede the adoption of clinical PGx testin...
Abstract
Cited 14 times since 2015 (1.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 17, Issue 11, 20 3 2015, Pages 1269-1278
Sustained favourable haemodynamics 1 year after TAVI: improvement in NYHA functional class related to improvement of left ventricular diastolic function.
Muratori M, Fusini L, Tamborini G, Gripari P, Delgado V, Marsan NA, Ghulam Ali S, Barbier P, Bartorelli AL, Alamanni F, Pepi M
Aims: Despite expected improvement in left ventricular (LV) systolic and diastolic function after transcatheter aortic valve implantation (TAVI), the complex relationship between pre-existent LV systolic and diastolic function and changes in LV haemodynamics and clinical symptoms have been scarcely investigated. This study investigated the presence of pre-operative LV diastolic dysfunction and its improvement over time after TAVI alongside improvement in New York Heart Association (NYHA) class i...
Abstract
Cited 5 times since 2015 (0.5 per year)
source: EuropePMC
PloS one,
Volume 10, Issue 11, 20 3 2015, Pages e0143079
Candidate Gene Analysis of Mortality in Dialysis Patients.
Rothuizen TC, Ocak G, Verschuren JJ, Dekker FW, Rabelink TJ, Jukema JW, Rotmans JI
Background: Dialysis patients have high cardiovascular mortality risk. This study aimed to investigate the association between SNPs of genes involved in vascular processes and mortality in dialysis patients. Methods: Forty two SNPs in 25 genes involved in endothelial function, vascular remodeling, cell proliferation, inflammation, coagulation and calcium/phosphate metabolism were genotyped in 1330 incident dialysis patients. The effect of SNPs on 5-years cardiovascular and non-cardiovascular mor...
Abstract
Cited 4 times since 2015 (0.4 per year)
source: EuropePMC
JIMD reports,
Volume 28, 14 2 2015, Pages 95-103
In Patients with an α-Galactosidase A Variant, Small Nerve Fibre Assessment Cannot Confirm a Diagnosis of Fabry Disease.
van der Tol L, Verhamme C, van Schaik IN, van der Kooi AJ, Hollak CE, Biegstraaten M
Background: Fabry disease (FD) is an X-linked lysosomal storage disorder caused by an α-galactosidase A enzyme deficiency due to pathogenic variants in the α-galactosidase A gene (GLA). An increasing number of individuals with a GLA variant, but without characteristic FD features, are identified. A definite diagnosis of FD has important consequences for treatment and counselling. Objectives: We assessed the diagnostic value of quantitative sensory testing (QST) and intraepidermal nerve fibre den...
Abstract
Cited 4 times since 2015 (0.4 per year)
source: EuropePMC
NPJ aging and mechanisms of disease,
Volume 1, 12 2 2015, Pages 15011
Fine mapping the <i>CETP</i> region reveals a common intronic insertion associated to HDL-C.
van Leeuwen EM, Huffman JE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Feitosa MF, Duan Q, Schraut KE, Navarro P, van Vliet-Ostaptchouk JV, Zhu G, Mbarek H, Trompet S, Verweij N, Lyytikäinen LP, Deelen J, Nolte IM, van der Laan SW, Davies G, Vermeij-Verdoold AJ, van Oosterhout AA, Vergeer-Drop JM, Arking DE, Trochet H, Generation Scotland, Medina-Gomez C, Rivadeneira F, Uitterlinden AG, Dehghan A, Franco OH, Sijbrands EJ, Hofman A, White CC, Mychaleckyj JC, Peloso GM, Swertz MA, LifeLines Cohort Study, Willemsen G, de Geus EJ, Milaneschi Y, Penninx BW, Ford I, Buckley BM, de Craen AJ, Starr JM, Deary IJ, Pasterkamp G, Oldehinkel AJ, Snieder H, Slagboom PE, Nikus K, Kähönen M, Lehtimäki T, Viikari JS, Raitakari OT, van der Harst P, Jukema JW, Hottenga JJ, Boomsma DI, Whitfield JB, Montgomery G, Martin NG, CHARGE Lipids Working Group, Polasek O, Vitart V, Hayward C, Kolcic I, Wright AF, Rudan I, Joshi PK, Wilson JF, Lange LA, Wilson JG, Gudnason V, Harris TB, Morrison AC,
Background: Individuals with exceptional longevity and their offspring have significantly larger high-density lipoprotein concentrations (HDL-C) particle sizes due to the increased homozygosity for the I405V variant in the cholesteryl ester transfer protein (CETP) gene. In this study, we investigate the association of CETP and HDL-C further to identify novel, independent CETP variants associated with HDL-C in humans. Methods: We performed a meta-analysis of HDL-C within the CETP region using 59,...
Abstract
Cited 58 times since 2015 (6.1 per year)
source: EuropePMC
American journal of human genetics,
Volume 97, Issue 6, 12 2 2015, Pages 775-789
Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.
Palamara PF, Francioli LC, Wilton PR, Genovese G, Gusev A, Finucane HK, Sankararaman S, Genome of the Netherlands Consortium, Sunyaev SR, de Bakker PI, Wakeley J, Pe'er I, Price AL
The rate at which human genomes mutate is a central biological parameter that has many implications for our ability to understand demographic and evolutionary phenomena. We present a method for inferring mutation and gene-conversion rates by using the number of sequence differences observed in identical-by-descent (IBD) segments together with a reconstructed model of recent population-size history. This approach is robust to, and can quantify, the presence of substantial genotyping error, as val...
Abstract
Cited 7 times since 2015 (0.7 per year)
source: EuropePMC
Heart rhythm,
Volume 13, Issue 2, 11 2 2015, Pages 504-510
Troponin levels after ICD implantation with and without defibrillation testing and their predictive value for outcomes: Insights from the SIMPLE trial.
Vamos M, Healey JS, Wang J, Duray GZ, Connolly SJ, van Erven L, Vinolas X, Neuzner J, Glikson M, Hohnloser SH
Background: The Shockless IMPLant Evaluation trial randomized 2500 patients receiving a first implantable cardioverter-defibrillator (ICD)/cardiac resynchronization therapy-defibrillator device to have either defibrillation testing (DT) or no DT. It demonstrated that DT did not improve shock efficacy or reduce mortality. Objective: This prospective substudy evaluated the effect of DT on postoperative troponin levels and their predictive value for total and arrhythmic mortality. Methods: Troponin...
Abstract
Cited 62 times since 2015 (6.5 per year)
source: EuropePMC
Human molecular genetics,
Volume 25, Issue 2, 10 2 2015, Pages 358-370
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V, Hottenga JJ, Trompet S, Müller-Nurasyid M, Zhao JH, Brody JA, Kleber ME, Guo X, Wang JJ, Auer PL, Attia JR, Yanek LR, Ahluwalia TS, Lahti J, Venturini C, Tanaka T, Bielak LF, Joshi PK, Rocanin-Arjo A, Kolcic I, Navarro P, Rose LM, Oldmeadow C, Riess H, Mazur J, Basu S, Goel A, Yang Q, Ghanbari M, Willemsen G, Rumley A, Fiorillo E, de Craen AJ, Grotevendt A, Scott R, Taylor KD, Delgado GE, Yao J, Kifley A, Kooperberg C, Qayyum R, Lopez LM, Berentzen TL, Räikkönen K, Mangino M, Bandinelli S, Peyser PA, Wild S, Trégouët DA, Wright AF, Marten J, Zemunik T, Morrison AC, Sennblad B, Tofler G, de Maat MP, de Geus EJ, Lowe GD, Zoledziewska M, Sattar N, Binder H, Völker U, Waldenberger M, Khaw KT, Mcknight B, Huang J, Jenny NS, Holliday EG, Qi L, Mcevoy MG, Becker DM, Starr JM, Sarin AP, Hysi PG, Hernandez DG, Jhun MA, Campbell H, Hamsten A, Rivadeneira F, Mcardle WL, Slagboom PE, Zeller T, Koenig W, Psat
Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better coverage of uncommon variants, and includes indels. We conducted a genome-wide association analysis of 34 studies imputed to the 1000 Genomes Project reference panel and including ∼120 000 participants of European ancestry (95 806 participants with data on...
Abstract
Cited 3 times since 2015 (0.3 per year)
source: EuropePMC
Environmental pollution (Barking, Essex : 1987),
Volume 208, Issue Pt B, 6 1 2015, Pages 361-370
Assessment of biological effects of environmental pollution in Mersin Bay (Turkey, northeastern Mediterranean Sea) using Mullus barbatus and Liza ramada as target organisms.
Yılmaz D, Kalay M, Dönmez E, Yılmaz N
The increasing emphasis on the assessment and monitoring of marine ecosystems has revealed the need to use appropriate biological indicators for these areas. Enzyme activities and histopathology are increasingly being used as indicators of environmental stress since they provide a definite biological end-point of pollutant exposure. As part of an ecotoxicological assessment of Mersin Bay, EROD enzyme activity and histopathological response in selected organs and tissues of two species of fish, M...
Abstract
Cited 3 times since 2015 (0.3 per year)
source: EuropePMC
BMJ case reports,
Volume 2015, 5 1 2015, Pages bcr2015212271
Enterobius vermicularis infection of the liver in a patient with colorectal carcinoma with suspected liver metastasis.
Furnée EJ, Spoto C, de Graaf MJ, Smakman N
A 68-year-old man diagnosed with cT3N2 adenocarcinoma of the rectum presented with a synchronous solitary liver metastasis on CT scan. Neoadjuvant chemoradiotherapy was started to downstage the primary tumour. Resection of the rectal tumour followed 3 months after the last radiotherapy session and primary resection of the isolated liver lesion was performed in the intervening period. Histopathological assessment of the liver lesion, however, showed no malignancy, but did reveal a necrotic infect...
Abstract
Cited 43 times since 2015 (4.5 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 101, Issue 24, 5 1 2015, Pages 1989-1995
Contemporary survival of adults with congenital heart disease.
van der Bom T, Mulder BJ, Meijboom FJ, van Dijk AP, Pieper PG, Vliegen HW, Konings TC, Zwinderman AH, Bouma BJ
Background: Survival data that are applicable to the current population of adults with congenital heart disease (CHD) are not available. Objectives: Using an alternative survival analysis with age as the primary time scale, we assessed the contemporary survival of adult patients with CHD. Methods: Survival was assessed using prospective data of the national registry of adult patients with CHD of the Netherlands. Survival was stratified by severity and lesion, and compared with a standardised gen...
Abstract
Cited 91 times since 2015 (9.5 per year)
source: EuropePMC
Circulation. Cardiovascular genetics,
Volume 8, Issue 6, 4 1 2015, Pages 832-841
Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium.
Linneberg A, Jacobsen RK, Skaaby T, Taylor AE, Fluharty ME, Jeppesen JL, Bjorngaard JH, Åsvold BO, Gabrielsen ME, Campbell A, Marioni RE, Kumari M, Marques-Vidal P, Kaakinen M, Cavadino A, Postmus I, Ahluwalia TS, Wannamethee SG, Lahti J, Räikkönen K, Palotie A, Wong A, Dalgård C, Ford I, Ben-Shlomo Y, Christiansen L, Kyvik KO, Kuh D, Eriksson JG, Whincup PH, Mbarek H, de Geus EJ, Vink JM, Boomsma DI, Smith GD, Lawlor DA, Kisialiou A, McConnachie A, Padmanabhan S, Jukema JW, Power C, Hyppönen E, Preisig M, Waeber G, Vollenweider P, Korhonen T, Laatikainen T, Salomaa V, Kaprio J, Kivimaki M, Smith BH, Hayward C, Sørensen TI, Thuesen BH, Sattar N, Morris RW, Romundstad PR, Munafò MR, Jarvelin MR, Husemoen LL
Background: Smoking is an important cardiovascular disease risk factor, but the mechanisms linking smoking to blood pressure are poorly understood. Methods and results: Data on 141 317 participants (62 666 never, 40 669 former, 37 982 current smokers) from 23 population-based studies were included in observational and Mendelian randomization meta-analyses of the associations of smoking status and smoking heaviness with systolic and diastolic blood pressure, hypertension, and resting heart rate....
Abstract
Cited 2 times since 2015 (0.2 per year)
source: EuropePMC
Expert review of cardiovascular therapy,
Volume 14, Issue 1, 4 1 2015, Pages 75-86
The role of multimodality imaging in the selection of patients for aortic valve repair.
Regeer MV, Versteegh MI, Marsan NA, Bax JJ, Delgado V
Aortic valve sparing surgery for aortic regurgitation and/or aortopathy serves as an alternative to aortic valve and root replacement. One of the advantages of aortic valve sparing surgery over conventional replacement is that there is no need for life-long anticoagulation, which is particularly attractive in young patients who may receive a mechanical prosthesis otherwise. However, successful aortic valve repair requires high expertise. At present, reparability is determined intraoperatively by...
Abstract
