Research

Publications

Below you can find a list of our published research.

6125 results

Cited 11 times since 2006 (0.6 per year) source: EuropePMC

Journal of clinical microbiology, Volume 44, Issue 3, 1 1 2006, Pages 1197-1201 Use of enzyme-linked immunospot assay with Mycobacterium tuberculosis-specific peptides for diagnosis of recent infection with M. tuberculosis after accidental laboratory exposure. Leyten EM, Mulder B, Prins C, Weldingh K, Andersen P, Ottenhoff TH, van Dissel JT, Arend SM

This report of an accidental exposure to Mycobacterium tuberculosis in a microbiological laboratory illustrates the value of gamma interferon enzyme-linked immunospot assay using peptides of ESAT-6, CFP-10, TB37.6, and TB7.7 for the diagnosis of latent infection. In particular, positive responses to peptides 2 to 6 of TB37.6 were observed exclusively in recently infected persons. Abstract

Cited 18 times since 2006 (0.9 per year) source: EuropePMC

Nature clinical practice. Cardiovascular medicine, Volume 3 Suppl 1, 1 1 2006, Pages S94-100 Intramyocardial injection of skeletal myoblasts: long-term follow-up with pressure-volume loops. Steendijk P, Smits PC, Valgimigli M, van der Giessen WJ, Onderwater EE, Serruys PW

The human heart has a limited capacity for self-repair because, unlike most other cells, cardiomyocytes do not regenerate. Therefore, if a substantial number of myocytes is lost after a myocardial infarction, the performance of the heart may become severely limited, leading to a condition of heart failure. Recently, cell transplantation has emerged as a potential therapy for patients with end-stage heart failure. Of the various cell types being investigated for this purpose, skeletal myoblasts a... Abstract

Nederlands tijdschrift voor geneeskunde, Volume 150, Issue 11, 1 1 2006, Pages 597-600 [Screening of asymptomatic individuals for coronary disease using CT-calcium measurement in the coronary arteries]. Schuijf JD, Bax JJ, Jukema JW, van der Wall EE

Coronary calcification is a specific marker for coronary atherosclerosis. It is therefore reasonable to assume that the risk ofcardiac events can be assessed by the quantification of the extent of coronary calcium. Until now, the predictive value of coronary calcium and its advantage over conventional risk factors has not been proven by any of the available prospective cohort studies. It is particularly likely that assessment of coronary atherosclerosis will help in the decision to initiate or d... Abstract

Cited 31 times since 2006 (1.6 per year) source: EuropePMC

Coronary artery disease, Volume 17, Issue 2, 1 1 2006, Pages 173-179 A meta-analysis of safety and effectiveness of perioperative beta-blocker use for the prevention of cardiac events in different types of noncardiac surgery. Schouten O, Shaw LJ, Boersma E, Bax JJ, Kertai MD, Feringa HH, Biagini E, Kok NF, Urk Hv, Elhendy A, Poldermans D

Objective: Perioperative beta-blocker therapy has been proposed to improve outcome. Most of the trials conducted, however, lacked statistical power to evaluate the incidence of hard cardiac events and the relationship to the type of surgery. Therefore, we conducted a meta-analysis of all randomized controlled trials in which beta-blocker therapy was evaluated. Methods: An electronic search of published reports on Medline was undertaken to identify studies published between January 1980 and Novem... Abstract

Cited 16 times since 2006 (0.8 per year) source: EuropePMC

Seminars in cardiothoracic and vascular anesthesia, Volume 10, Issue 1, 1 1 2006, Pages 25-31 Protecting the heart with cardiac medication in patients with left ventricular dysfunction undergoing major noncardiac vascular surgery. Feringa HH, Bax JJ, Schouten O, Poldermans D

Patients with left ventricular dysfunction who are undergoing major noncardiac vascular surgery are at increased risk of adverse postoperative events. We sought to evaluate whether perioperative medication use, including angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, statins, and aspirin, was associated with a reduced incidence of postoperative in-hospital mortality in these high-risk patients. The study enrolled 511 patients with left ventricular dysfunction (left ventricular ej... Abstract

Cited 75 times since 2006 (3.9 per year) source: EuropePMC

Archives of internal medicine, Volume 166, Issue 5, 1 1 2006, Pages 529-535 The long-term prognostic value of the resting and postexercise ankle-brachial index. Feringa HH, Bax JJ, van Waning VH, Boersma E, Elhendy A, Schouten O, Tangelder MJ, van Sambeek MH, van den Meiracker AH, Poldermans D

Background: Peripheral arterial disease is associated with a high incidence of cardiovascular mortality. Peripheral arterial disease can be detected by using the ankle-brachial index (ABI). This study assessed the prognostic value of the postexercise ABI in addition to the resting ABI on long-term mortality in patients with suspected peripheral arterial disease. Methods: In this prospective cohort study of 3209 patients (mean +/- SD age, 63 +/- 12 years; 71.1% male), resting and postexercise ABI... Abstract

Cited 28 times since 2006 (1.5 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 13, Issue 2, 1 1 2006, Pages 210-219 Prediction of functional recovery after revascularization in patients with coronary artery disease and left ventricular dysfunction by gated FDG-PET. Slart RH, Bax JJ, van Veldhuisen DJ, van der Wall EE, Dierckx RA, de Boer J, Jager PL

Background: Traditionally, cardiac fluorodeoxyglucose (FDG) uptake is combined with regional perfusion for optimal evaluation of viability. Gated FDG-positron emission tomography (PET) may be an alternative technique for detection of viability because it permits combined assessment of glucose metabolism uptake and wall thickening (WT). In this study the value of FDG uptake and WT (analyzed from a stand-alone gated FDG-PET study) for the prediction of recovery of regional and global left ventricu... Abstract

Cited 1 times since 2006 (0.1 per year) source: EuropePMC

European journal of nuclear medicine and molecular imaging, Volume 33, Issue 3, 1 1 2006, Pages 353-355 MSCT is better than stress perfusion imaging for detecting CAD--For. Cademartiri F, Bax JJ

Abstract

Cited 66 times since 2006 (3.5 per year) source: EuropePMC

Heart rhythm, Volume 3, Issue 5, 28 4 2006, Pages 526-535 Ablation of focal atrial arrhythmia in patients with congenital heart defects after surgery: role of circumscribed areas with heterogeneous conduction. de Groot NM, Zeppenfeld K, Wijffels MC, Chan WK, Blom NA, Van der Wall EE, Schalij MJ

Background: In patients late after surgical repair of congenital heart disease (CHD), areas with abnormal electrophysiologic properties may serve as slow conducting pathways within a macroreentrant circuit or may be the source of focal atrial tachycardia. Objectives: The purpose of this study was to evaluate the role of abnormal areas during focal atrial tachycardia prior to ablation. Methods: Electroanatomic activation mapping of 62 atrial tachycardias was performed in 43 consecutive patients (... Abstract

Cited 10 times since 2006 (0.5 per year) source: EuropePMC

The American journal of cardiology, Volume 97, Issue 8, 28 4 2006, Pages 1146-1150 Relation of B-type natriuretic peptide early after acute myocardial infarction to left ventricular diastolic function and extent of myocardial damage determined by magnetic resonance imaging. Paelinck BP, Vrints CJ, Bax JJ, Bosmans JM, De Hert SG, de Roos A, Lamb HJ

Early after acute myocardial infarction, the relation between plasma B-type natriuretic peptide (BNP) and extent of myocardial scar formation and diastolic dysfunction remains unclear. In 32 consecutive patients early (5 +/- 3 days) after a first acute myocardial infarction, delayed contrast-enhanced magnetic resonance (MR) imaging was performed to define myocardial scar. Diastolic function was assessed using phase-contrast MR measurements of mitral flow and septal tissue velocities (tissue MR i... Abstract

Cited 45 times since 2006 (2.4 per year) source: EuropePMC

The American journal of cardiology, Volume 97, Issue 7, 28 4 2006, Pages 1103-1106 Prognostic value of routine preoperative electrocardiography in patients undergoing noncardiac surgery. Noordzij PG, Boersma E, Bax JJ, Feringa HH, Schreiner F, Schouten O, Kertai MD, Klein J, van Urk H, Elhendy A, Poldermans D

Electrocardiography is commonly performed as part of preoperative cardiovascular risk assessment in patients undergoing noncardiac surgery. However, the prognostic value of such electrocardiography is still not clear. This study retrospectively studied 23,036 patients who underwent 28,457 surgical procedures at Erasmus Medical Center from 1991 to 2000. Patients were screened before surgery by type of surgery, cardiovascular risk factors (history of coronary heart disease, heart failure, diabetes... Abstract

Cited 88 times since 2006 (4.6 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 47, Issue 6, 23 4 2006, Pages 1182-1187 Cardioprotective medication is associated with improved survival in patients with peripheral arterial disease. Feringa HH, van Waning VH, Bax JJ, Elhendy A, Boersma E, Schouten O, Galal W, Vidakovic RV, Tangelder MJ, Poldermans D

Objectives: We sought to investigate the effect of cardiac medication on long-term mortality in patients with peripheral arterial disease (PAD). Background: Peripheral arterial disease is associated with increased cardiovascular morbidity and mortality. Treatment guidelines recommend aggressive management of risk factors and lifestyle modifications. However, the potential benefit of cardiac medication in patients with PAD remains ill defined. Methods: In this prospective observational cohort stu... Abstract

Cited 5 times since 2006 (0.3 per year) source: EuropePMC

European heart journal, Volume 27, Issue 6, 23 4 2006, Pages 631-632 Assessment of coronary artery disease in patients with (a)symptomatic diabetes. Bax JJ, van der Wall EE

Abstract

Cited 73 times since 2006 (3.8 per year) source: EuropePMC

The American journal of cardiology, Volume 97, Issue 7, 17 3 2006, Pages 1051-1055 Effects of volume and/or pressure overload secondary to congenital heart disease (tetralogy of fallot or pulmonary stenosis) on right ventricular function using cardiovascular magnetic resonance and B-type natriuretic peptide levels. Oosterhof T, Tulevski II, Vliegen HW, Spijkerboer AM, Mulder BJ

The aim of this study was to analyze the effect of pressure and/or volume overload on right ventricular (RV) function and brain natriuretic peptide (BNP) levels in patients with surgically corrected congenital heart disease. Forty-two consecutive patients aged 17 to 57 years (median 30) with congenital heart disease (32 with tetralogy of Fallot and 10 with pulmonary stenosis) were examined. The RV systolic pressure was estimated using Doppler echocardiography. Cardiovascular magnetic resonance i... Abstract

Cited 465 times since 2006 (24.4 per year) source: EuropePMC

Circulation, Volume 113, Issue 7, 13 2 2006, Pages 969-976 Effect of posterolateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy. Bleeker GB, Kaandorp TA, Lamb HJ, Boersma E, Steendijk P, de Roos A, van der Wall EE, Schalij MJ, Bax JJ

Background: Currently, one third of patients treated with cardiac resynchronization therapy (CRT) do not respond. Nonresponse to CRT may be explained by the presence of scar tissue in the posterolateral left ventricular (LV) segments, which may result in ineffective LV pacing and inadequate LV resynchronization. In the present study, the relationship between transmural posterolateral scar tissue and response to CRT was evaluated. Methods and results: Forty consecutive patients with end-stage hea... Abstract

Cited 243 times since 2006 (12.7 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 26, Issue 4, 9 2 2006, Pages 716-728 Pericellular proteases in angiogenesis and vasculogenesis. van Hinsbergh VW, Engelse MA, Quax PH

Pericellular proteases play an important role in angiogenesis and vasculogenesis. They comprise (membrane-type) matrix metalloproteinases [(MT-)MMPs], serine proteases, cysteine cathepsins, and membrane-bound aminopeptidases. Specific inhibitors regulate them. Major roles in initiating angiogenesis have been attributed to MT1-matrix metalloproteinase (MMP), MMP-2, and MMP-9. Whereas MT-MMPs are membrane-bound by nature, MMP-2 and MMP-9 can localize to the membrane by binding to alphavbeta3-integ... Abstract

Cited 18 times since 2006 (0.9 per year) source: EuropePMC

Archives of surgery (Chicago, Ill. : 1960), Volume 141, Issue 2, 1 1 2006, Pages 161-6; discussion 166 Clinical indicators and psychosocial aspects in peripheral arterial disease. Aquarius AE, De Vries J, Henegouwen DP, Hamming JF

Hypothesis: Patients with peripheral arterial disease (PAD) often experience substantial impairment in health status and quality of life (QOL), but factors associated with these outcomes are unknown. We hypothesized that subjective pain symptoms in the legs and social support and stress (the degree to which situations are appraised as stressful) are associated with impaired health status and QOL. Design: Cross-sectional observational study. Setting: Vascular outpatient clinic of a teaching hospi... Abstract

Nederlands tijdschrift voor geneeskunde, Volume 150, Issue 8, 1 1 2006, Pages 413-414 [Mechanical circulatory support after paediatric cardiac surgery]. Hazekamp MG

When circulatory failure occurs after paediatric cardiac surgery despite conventional therapy (inotropic medication, optimising pre- and afterload) mechanical assist devices can be used. Assist devices can be categorised in different ways: according to the type of pump used (centrifugal, axial flow, or pneumatic), according to univentricular or biventricular support and in relation to the presence of an oxygenator. Paediatric devices are non-implantable. Extra-corporeal membrane oxygenation (ECM... Abstract

Cited 53 times since 2006 (2.8 per year) source: EuropePMC

American heart journal, Volume 151, Issue 2, 1 1 2006, Pages 265-272 Cardiovascular magnetic resonance in the follow-up of patients with corrected tetralogy of Fallot: a review. Oosterhof T, Mulder BJ, Vliegen HW, de Roos A

Cardiovascular magnetic resonance (CMR) is becoming an important tool in the clinical management of patients with congenital heart disease. Because of the diverse problems patients may face after initial correction for tetralogy of Fallot and the large amount of CMR techniques that can be applied, creating a patient-orientated imaging protocol is a difficult issue. Although it is still not certain what the impact of some parameters, provided by CMR, should be on clinical decision making, new tec... Abstract

Cited 7 times since 2006 (0.4 per year) source: EuropePMC

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 1, Issue 4, 1 1 2006, Pages 417-424 Myocardial repair by percutaneous cell transplantation of autologous skeletal myoblast as a stand alone procedure in post myocardial infarction chronic heart failure patients. Smits PC, Nienaber C, Colombo A, Ince H, Carlino M, Theuns DA, Biagini E, Valgimigli M, Onderwater EE, Steendijk P, Peters NS, Goedhart DM, Serruys PW

Aims: In this first multicentre study we assessed the safety and efficacy of percutaneous transendocardial skeletal myoblast injection as a stand alone procedure in congestive heart failure patients. Methods and results: 15 patients (14 male), age 63+/-7 (Mean+/-SD), NYHA class 2-4 were injected with 216+/-119 cells (81+/-19% Desmin+) using a NOGA or fluoroscopy guided injection catheter. The cells were injected in the scarred regions 6+/-4 years after myocardial infarction as a stand alone proc... Abstract