9401 results
Cited 17 times since 2020 (3.7 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 11, 19 3 2020, Pages 2386-2396
Sex Differences in Compositional Plaque Volume Progression in Patients With Coronary Artery Disease.
Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
Objectives: This study sought to explore sex-based differences in total and compositional plaque volume (PV) progression. Background: It is unclear whether sex has an impact on PV progression in patients with coronary artery disease (CAD). Methods: The study analyzed a prospective multinational registry of consecutive patients with suspected CAD who underwent 2 or more clinically indicated coronary computed tomography angiography (CTA) at ≥2-year intervals. Total and compositional PV at baseline...
Abstract
Cited 12 times since 2020 (2.6 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 4, 19 3 2020, Pages 730-739
Regurgitant Volume/Left Ventricular End-Diastolic Volume Ratio: Prognostic Value in Patients With Secondary Mitral Regurgitation.
Namazi F, van der Bijl P, Fortuni F, Mertens BJA, Kamperidis V, van Wijngaarden SE, Stone GW, Narula J, Ajmone Marsan N, Vahanian A, Delgado V, Bax JJ
Objectives: The purpose of this study was to investigate the prognostic implications of the ratio of mitral regurgitant volume (RVol) to left ventricular (LV) end-diastolic volume (EDV) in patients with significant secondary mitral regurgitation (MR). Background: Quantification of secondary MR remains challenging, and its severity can be over- or underestimated when using the proximal isovelocity surface area method, which does not take LV volume into account. This limitation can be addressed by...
Abstract
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 97, Issue 3, 18 3 2020, Pages 488-492
Reverse remodeling after percutaneous transluminal septal myocardial ablation in severe but asymptomatic LVOT obstruction (RASTA) study: Rationale and design of transcatheter septal reduction in asymptomatic patients with severe hypertrophic obstructive cardiomyopathy.
Arslan F, Akdim F, Ten Berg JM
Objectives: The aim of this study is to evaluate the impact of percutaneous transluminal septal myocardial ablation (PTSMA) on remodeling in asymptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM) and severe left ventricular outflow tract (LVOT) obstruction. Background: Symptoms justify invasive treatment in HOCM patients with LVOT obstruction. Adverse structural and functional changes (remodeling) in the heart occur preceding heart failure and sudden cardiac death. Early invas...
Abstract
Cited 11 times since 2020 (2.4 per year)
source: EuropePMC
BMC genomics,
Volume 21, Issue 1, 18 3 2020, Pages 568
Conditionally essential genes for survival during starvation in Enterococcus faecium E745.
de Maat V, Arredondo-Alonso S, Willems RJL, van Schaik W
Background: The nosocomial pathogen Enterococcus faecium can survive for prolonged periods of time on surfaces in the absence of nutrients. This trait is thought to contribute to the ability of E. faecium to spread among patients in hospitals. There is currently a lack of data on the mechanisms that are responsible for the ability of E. faecium to survive in the absence of nutrients. Results: We performed a high-throughput transposon mutant library screening (Tn-seq) to identify genes that have...
Abstract
The American journal of emergency medicine,
Volume 38, Issue 12, 15 3 2020, Pages 2762
Corrigendum to "Clinical Use of Copeptin in Migraine Patients Admitted to the Emergency Department" [American Journal of Emergency Medicine, Volume 38, Issue 9, September 2020, P1910-1914].
Yilmaz DY, Armağan HH, Karaman K, Şirin FB, Bozkurt M, Karaibrahimoğlu A, Yalçin İG, Beceren NG, Tomruk Ö
Abstract
Cited 10 times since 2020 (2.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 134, 15 3 2020, Pages 116-122
Comparison of the Usefulness of Strain Imaging by Echocardiography Versus Computed Tomography to Detect Right Ventricular Systolic Dysfunction in Patients With Significant Secondary Tricuspid Regurgitation.
Hirasawa K, van Rosendael PJ, Dietz MF, Ajmone Marsan N, Delgado V, Bax JJ
Assessment of right ventricular (RV) systolic function in patients with significant secondary tricuspid regurgitation (STR) remains challenging. In patients with severe aortic stenosis treated with transcatheter aortic valve implantation (TAVI), STR and RV enlargement have been associated with poor outcomes. In these patients, speckle tracking echocardiography (STE) may detect RV systolic dysfunction better than 3-dimensional (3D) RV ejection fraction (EF). The purpose of this study was to inves...
Abstract
Cited 44 times since 2020 (9.6 per year)
source: EuropePMC
Circulation. Genomic and precision medicine,
Volume 13, Issue 5, 14 2 2020, Pages 541-547
Metabolic Age Based on the BBMRI-NL <sup>1</sup>H-NMR Metabolomics Repository as Biomarker of Age-related Disease.
van den Akker EB, Trompet S, Barkey Wolf JJH, Beekman M, Suchiman HED, Deelen J, Asselbergs FW, Boersma E, Cats D, Elders PM, Geleijnse JM, Ikram MA, Kloppenburg M, Mei H, Meulenbelt I, Mooijaart SP, Nelissen RGHH, Netea MG, Penninx BWJH, Slofstra M, Stehouwer CDA, Swertz MA, Teunissen CE, Terwindt GM, 't Hart LM, van den Maagdenberg AMJM, van der Harst P, van der Horst ICC, van der Kallen CJH, van Greevenbroek MMJ, van Spil WE, Wijmenga C, Zhernakova A, Zwinderman AH, Sattar N, Jukema JW, van Duijn CM, Boomsma DI, Reinders MJT, Slagboom PE
Background: The blood metabolome incorporates cues from the environment and the host's genetic background, potentially offering a holistic view of an individual's health status. Methods: We have compiled a vast resource of proton nuclear magnetic resonance metabolomics and phenotypic data encompassing over 25 000 samples derived from 26 community and hospital-based cohorts. Results: Using this resource, we constructed a metabolomics-based age predictor (metaboAge) to calculate an indiv...
Abstract
Cited 3 times since 2020 (0.7 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 60, Issue 5, 13 2 2020, Pages 655-662
Editor's Choice - A Systemic Evaluation of the Costs of Elective EVAR and Open Abdominal Aortic Aneurysm Repair Implies Cost Equivalence.
Bulder RMA, Eefting D, Vriens PWHE, van Tongeren RB, Matsumura JS, van den Hout WB, Hamming JF, Lindeman JHN
Objective: The suggested high costs of endovascular aneurysm repair (EVAR) hamper the choice of insurance companies and financial regulators for EVAR as the primary option for elective abdominal aortic aneurysm (AAA) repair. However, arguments used in this debate are impeded by time related aspects such as effect modification and the introduction of confounding by indication, and by asymmetric evaluation of outcomes. Therefore, a re-evaluation minimising the impact of these interferences was con...
Abstract
Cited 5 times since 2020 (1.1 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 98, Issue 4, 13 2 2020, Pages 691-700
Clinical relevance of adding intravascular ultrasound to coronary angiography for the diagnosis of extrinsic left main coronary artery compression by a pulmonary artery aneurysm in pulmonary hypertension.
Velázquez Martín M, Montero Cabezas JM, Huertas S, Nuche J, Albarrán A, Delgado JF, Alonso S, Sarnago F, Arribas F, Escribano Subias P
Objectives: We sought to assess the clinical value of adding intravascular ultrasound (IVUS) evaluation to coronary angiography (CA) to guide extrinsic left main coronary artery (LMCA) compression diagnosis and treatment in pulmonary hypertension (PH). Background: LMCA compression due to a pulmonary artery aneurysm (PAA) is a severe complication of PH. Although guidelines encourage the use of IVUS for LMCA disease evaluation, it has hardly been used in this scenario. Methods: We analyzed morbimo...
Abstract
Cited 3 times since 2020 (0.7 per year)
source: EuropePMC
Langenbeck's archives of surgery,
Volume 405, Issue 6, 11 2 2020, Pages 851-859
Outcomes of parathyroidectomy versus calcimimetics for secondary hyperparathyroidism and kidney transplantation: a propensity-matched analysis.
Koh EY, van der Plas WY, Dulfer RR, Pol RA, Kruijff S, Rotmans JI, Appelman-Dijkstra N, Schepers A, de Borst MH, Hoorn EJ, van Ginhoven TM, Nieveen van Dijkum EJM, Vogt L, Engelsman AF, Dutch Hyperparathyroidism Study Group
Purpose: Calcimimetics are currently indicated for severe secondary hyperparathyroidism (SHPT). However, the role of parathyroidectomy (PTX) for these patients is still under debate, and its impact on subsequent kidney transplantation (KTX) is unclear. In this study, we compare the outcomes of kidney transplantation after PTX or medical treatment. Methods: Patients who underwent KTX and had SHPT were analyzed retrospectively. Two groups were selected (patients who had either PTX or calcimimetics...
Abstract
Cited 4 times since 2020 (0.9 per year)
source: EuropePMC
Obesity facts,
Volume 13, Issue 4, 11 2 2020, Pages 361-370
Experiences with Glucagon-Like Peptide-1 Receptor Agonist in Children with Acquired Hypothalamic Obesity.
van Schaik J, Begijn DGA, van Iersel L, Vergeer Y, Hoving EW, Peeters B, van Santen HM
Objective: Hypothalamic obesity (HO) in children after treatment for a tumor in the suprasellar region has severe implications. Previous studies have shown various effects of glucagon-like peptide-1 (GLP-1) receptor agonist in acquired HO, but in adults only. We present our experience of GLP-1 receptor agonist (exenatide) treatment during a 1-year period on body mass index (BMI) in children with acquired HO. Patients and methods: Children with severe weight gain after treatment for suprasellar t...
Abstract
Cited 4 times since 2020 (0.9 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 36, Issue 12, 10 2 2020, Pages 2357-2364
Per-lesion versus per-patient analysis of coronary artery disease in predicting the development of obstructive lesions: the Progression of AtheRosclerotic PlAque DetermIned by Computed TmoGraphic Angiography Imaging (PARADIGM) study.
Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
To determine whether the assessment of individual plaques is superior in predicting the progression to obstructive coronary artery disease (CAD) on serial coronary computed tomography angiography (CCTA) than per-patient assessment. From a multinational registry of 2252 patients who underwent serial CCTA at a ≥ 2-year inter-scan interval, patients with only non-obstructive lesions at baseline were enrolled. CCTA was quantitatively analyzed at both the per-patient and per-lesion level. Models pred...
Abstract
Cited 3 times since 2020 (0.7 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 60, Issue 4, 10 2 2020, Pages 632-633
Imaging Assessment of Carotid Artery Stenosis Varies in Clinical Practice.
Brouwers JJWM, Versluijs Y, van Walderveen MAA, Hamming JF, Schepers A
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
International journal of environmental research and public health,
Volume 17, Issue 16, 7 1 2020, Pages E5707
Automatic Process Comparison for Subpopulations: Application in Cancer Care.
Marazza F, Bukhsh FA, Geerdink J, Vijlbrief O, Pathak S, Keulen MV, Seifert C
Processes in organisations, such as hospitals, may deviate from the intended standard processes, due to unforeseeable events and the complexity of the organisation. For hospitals, the knowledge of actual patient streams for patient populations (e.g., severe or non-severe cases) is important for quality control and improvement. Process discovery from event data in electronic health records can shed light on the patient flows, but their comparison for different populations is cumbersome and time-c...
Abstract
Cited 3 times since 2020 (0.7 per year)
source: EuropePMC
European journal of medical genetics,
Volume 63, Issue 11, 7 1 2020, Pages 104032
Glutaric aciduria type 1: Genetic and phenotypic spectrum in 53 patients.
Gürbüz BB, Yılmaz DY, Coşkun T, Tokatlı A, Dursun A, Sivri HS
Introduction: Glutaric aciduria type 1 (GA1) is a rare and inherited autosomal-recessive metabolic disorder that occurs in the deficiency of glutaryl-co-enzyme A dehydrogenase (GCDH) enzyme encoded by GCDH gene. In this study, we aim to retrospectively investigate the clinical, biochemical, and neuroradiological parameters and examine the spectrum of GCDH gene variants in Turkish patients with glutaric aciduria type 1. Methods: This is a descriptive cross-sectional study. The study was conducted...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Clinical case reports,
Volume 8, Issue 11, 6 1 2020, Pages 2320-2321
The constrictive consequences of pericardial calcifications.
Egorova AD, Schalij MJ, Kiès P
A 53-year-old man presented with symptomatic severe pulmonary valve regurgitation. He underwent a diagnostic catheterization. A heavily calcified pericardium and the pressure tracings illustrate typical features of constrictive pericarditis physiology, including the "square root sign." This condition is important to recognize given the progressive nature and poor prognosis if untreated.
Abstract
Cited 71 times since 2020 (15.5 per year)
source: EuropePMC
Cancer immunology research,
Volume 8, Issue 10, 5 1 2020, Pages 1311-1321
CD39 Identifies the CD4<sup>+</sup> Tumor-Specific T-cell Population in Human Cancer.
Kortekaas KE, Santegoets SJ, Sturm G, Ehsan I, van Egmond SL, Finotello F, Trajanoski Z, Welters MJP, van Poelgeest MIE, van der Burg SH
The accumulation of tumor-specific CD4+ and CD8+ effector T cells is key to an effective antitumor response. Locally, CD4+ T cells promote the recruitment and effector function of tumor-specific CD8+ T cells and activate innate killer cells in the tumor. Here, we show that tumor-specific CD4+ T cells were predominantly present in the CD39+ subset of tumor-infiltrating lymphocytes (TIL). The CD39+ CD4+ and CD8+ TILs were detected in three different tumor types, and displayed an activated (PD-1+,...
Abstract
BMC medical education,
Volume 20, Issue 1, 5 1 2020, Pages 250
Refuting misconceptions in medical physiology.
Versteeg M, van Loon MH, Wijnen-Meijer M, Steendijk P
Background: In medical physiology, educators and students face a serious challenge termed misconceptions. Misconceptions are incorrect ideas that do not match current scientific views. Accordingly, they have shown to hamper teaching and learning of physiological concepts. Conceptual Change Theory forms the basis of new teaching and learning practices that may alleviate misconceptions and facilitate critical thinking skills that are essential in becoming knowledgeable, self-regulated health profe...
Abstract
Cited 13 times since 2020 (2.8 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 25, Issue 3, 5 1 2020, Pages 230-237
Placebo effect in chronic inflammatory demyelinating polyneuropathy: The PATH study and a systematic review.
Lewis RA, Cornblath DR, Hartung HP, Sobue G, Lawo JP, Mielke O, Durn BL, Bril V, Merkies ISJ, Bassett P, Cleasby A, van Schaik IN, PATH study group
The Polyneuropathy And Treatment with Hizentra (PATH) study required subjects with chronic inflammatory demyelinating polyneuropathy (CIDP) to show dependency on immunoglobulin G (IgG) and then be restabilized on IgG before being randomized to placebo or one of two doses of subcutaneous immunoglobulin (SCIG). Nineteen of the 51 subjects (37%) randomized to placebo did not relapse over the next 24 weeks. This article explores the reasons for this effect. A post-hoc analysis of the PATH placebo gr...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 28, Issue 5, 4 1 2020, Pages 2343-2345
Hybrid Positron emission tomography/magnetic resonance imaging in viability assessment.
Bax JJ, Ng ACT, Delgado V
Abstract
