6136 results
Cited 2 times since 2017 (0.2 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 10, Issue 3, 1 1 2017, Pages 286-295
Trials Testing the Value of Imaging Use in Valve Disease and in Transcatheter Valvular Interventions.
Leipsic J, Bax JJ, Webb JG, Martin R, Blanke P
The role of imaging in the diagnosis of valvular heart disease is well established through years of investigation and validation. However, the role of imaging in guiding the treatment decision-making for valvular heart disease is less well established, and there is a striking paucity of randomized trial data to help inform these decisions. Given this relative absence of randomized trial data, the present article highlights some of the most important knowledge gaps and defines meaningful opportun...
Abstract
Cited 174 times since 2017 (21.7 per year)
source: EuropePMC
European heart journal,
Volume 38, Issue 11, 1 1 2017, Pages 828-836
The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction.
van Hout GP, Bosch L, Ellenbroek GH, de Haan JJ, van Solinge WW, Cooper MA, Arslan F, de Jager SC, Robertson AA, Pasterkamp G, Hoefer IE
Aims: Myocardial infarction (MI) triggers an intense inflammatory response that is associated with infarct expansion and is detrimental for cardiac function. Interleukin (IL)-1β and IL-18 are key players in this response and are controlled by the NLRP3-inflammasome. In the current study, we therefore hypothesized that selective inhibition of the NLRP3-inflammasome reduces infarct size and preserves cardiac function in a porcine MI model. Methods and results: Thirty female landrace pigs were subj...
Abstract
Cited 15 times since 2017 (1.9 per year)
source: EuropePMC
European heart journal,
Volume 38, Issue 10, 1 1 2017, Pages 720-726
Prognostic implications of left ventricular global longitudinal strain in heart failure patients with narrow QRS complex treated with cardiac resynchronization therapy: a subanalysis of the randomized EchoCRT trial.
Bax JJ, Delgado V, Sogaard P, Singh JP, Abraham WT, Borer JS, Dickstein K, Gras D, Brugada J, Robertson M, Ford I, Krum H, Holzmeister J, Ruschitzka F, Gorcsan J
Aim: Left ventricular (LV) global longitudinal strain (GLS) reflects LV systolic function and correlates inversely with the extent of LV myocardial scar and fibrosis. The present subanalysis of the Echocardiography Guided CRT trial investigated the prognostic value of LV GLS in patients with narrow QRS complex. Methods and results: Left ventricular (LV) global longitudinal strain (GLS) was measured on the apical 2-, 4- and 3-chamber views using speckle tracking analysis. Measurement of baseline...
Abstract
Cited 19 times since 2017 (2.4 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 10, Issue 3, 1 1 2017, Pages e006239
Atrial Functional Mitral Regurgitation: From Mitral Annulus Dilatation to Insufficient Leaflet Remodeling.
Delgado V, Bax JJ
Abstract
Cited 35 times since 2017 (4.4 per year)
source: EuropePMC
European heart journal,
Volume 38, Issue 9, 1 1 2017, Pages 665-674
Computed tomography for planning transcatheter tricuspid valve therapy.
van Rosendael PJ, Kamperidis V, Kong WK, van Rosendael AR, van der Kley F, Ajmone Marsan N, Delgado V, Bax JJ
Aims: Percutaneous transcatheter tricuspid valve therapy is an evolving treatment option for patients with significant tricuspid regurgitation (TR) deemed too fragile for open heart surgery. The present study proposes comprehensive anatomical evaluation of the tricuspid valve, right ventricle (RV), and vena cavae and its spatial relationships with the right coronary artery (RCA) using computed tomography (CT) and investigates the implications for suitability for current technologies. Methods and...
Abstract
Cited 32 times since 2017 (4 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 10, Issue 3, 1 1 2017, Pages e005155
Sex Differences in Phenotypes of Bicuspid Aortic Valve and Aortopathy: Insights From a Large Multicenter, International Registry.
Kong WK, Regeer MV, Ng AC, McCormack L, Poh KK, Yeo TC, Shanks M, Parent S, Enache R, Popescu BA, Yip JW, Ma L, Kamperidis V, van der Velde ET, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
Background: This large multicenter, international bicuspid aortic valve (BAV) registry aimed to define the sex differences in prevalence, valve morphology, dysfunction (aortic stenosis/regurgitation), aortopathy, and complications (endocarditis and aortic dissection). Methods and results: Demographic, clinical, and echocardiographic data at first presentation of 1992 patients with BAV (71.5% men) were retrospectively analyzed. BAV morphology and valve function were assessed; aortopathy configura...
Abstract
Cited 20 times since 2017 (2.5 per year)
source: EuropePMC
Cardiovascular research,
Volume 113, Issue 3, 1 1 2017, Pages 354-366
Optogenetic manipulation of anatomical re-entry by light-guided generation of a reversible local conduction block.
Watanabe M, Feola I, Majumder R, Jangsangthong W, Teplenin AS, Ypey DL, Schalij MJ, Zeppenfeld K, de Vries AA, Pijnappels DA
Aims: Anatomical re-entry is an important mechanism of ventricular tachycardia, characterized by circular electrical propagation in a fixed pathway. It's current investigative and therapeutic approaches are non-biological, rather unspecific (drugs), traumatizing (electrical shocks), or irreversible (ablation). Optogenetics is a new biological technique that allows reversible modulation of electrical function with unmatched spatiotemporal precision using light-gated ion channels. We therefor...
Abstract
Cited 17 times since 2017 (2.1 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 51, Issue 3, 1 1 2017, Pages 532-538
Incidence and predictors of vasoplegia after heart failure surgery.
van Vessem ME, Palmen M, Couperus LE, Mertens B, Berendsen RR, Tops LF, Verwey HF, de Jonge E, Klautz RJ, Schalij MJ, Beeres SL
Objectives: Vasoplegia has been described as a complication after cardiac surgery, particularly in patients with a poor left ventricular ejection fraction. The aim of this study was to assess the incidence, survival and predictors of vasoplegia in patients undergoing heart failure surgery and to propose a risk model. Methods: A retrospective study including heart failure patients who underwent surgical left ventricular restoration, CorCap implantation or left ventricular assist device implantati...
Abstract
Cited 37 times since 2017 (4.6 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 25, Issue 3, 1 1 2017, Pages 181-185
2015 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: comments from the Dutch ACS working group.
Damman P, van 't Hof AW, Ten Berg JM, Jukema JW, Appelman Y, Liem AH, de Winter RJ
On behalf of the Dutch ACS working group, we discuss multiple recommendations which have been implemented in the 2015 ESC guidelines for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation.
Abstract
Cited 47 times since 2017 (5.9 per year)
source: EuropePMC
JAMA cardiology,
Volume 2, Issue 3, 1 1 2017, Pages 285-292
Prognostic Implications of Raphe in Bicuspid Aortic Valve Anatomy.
Kong WK, Delgado V, Poh KK, Regeer MV, Ng AC, McCormack L, Yeo TC, Shanks M, Parent S, Enache R, Popescu BA, Liang M, Yip JW, Ma LC, Kamperidis V, van Rosendael PJ, van der Velde ET, Ajmone Marsan N, Bax JJ
Importance: Little is known about the association between bicuspid aortic valve (BAV) morphologic findings and the degree of valvular dysfunction, presence of aortopathy, and complications, including aortic valve surgery, aortic dissection, and all-cause mortality. Objective: To investigate the association between BAV morphologic findings (raphe vs nonraphe) and the degree of valve dysfunction, presence of aortopathy, and prognosis (including need for aortic valve surgery, aortic dissection, and...
Abstract
Cited 4 times since 2017 (0.5 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 25, Issue 3, 1 1 2017, Pages 170-172
The management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: early invasive strategy for all?
Arslan F, Voskuil M
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 53, Issue 4, 28 4 2017, Pages 520-532
Adjusted Hospital Outcomes of Abdominal Aortic Aneurysm Surgery Reported in the Dutch Surgical Aneurysm Audit.
Lijftogt N, Vahl AC, Wilschut ED, Elsman BHP, Amodio S, van Zwet EW, Leijdekkers VJ, Wouters MWJM, Hamming JF, Dutch Society of Vascular Surgery, the Steering Committee of the Dutch Surgical Aneurysm Audit, and the Dutch Institute for Clinical Auditing
Objective/background: The Dutch Surgical Aneurysm Audit (DSAA) is mandatory for all patients with primary abdominal aortic aneurysms (AAAs) in the Netherlands. The aims are to present the observed outcomes of AAA surgery against the predicted outcomes by means of V-POSSUM (Vascular-Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity). Adjusted mortality was calculated by the original and re-estimated V(physiology)-POSSUM for hospital comparisons. Methods: Al...
Abstract
Cited 8 times since 2017 (1 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 103, Issue 6, 24 4 2017, Pages 1976-1983
Long-Term Follow-Up After the Ross Procedure: A Single Center 22-Year Experience.
Schneider AW, Putter H, Klautz RJM, Bruggemans EF, Holman ER, Bökenkamp R, Hazekamp MG
Background: The aim of this study was to analyze long-term outcomes after the Ross procedure, focusing on autograft function and risk of reoperation in time. Methods: Between February 1994 and February 2016, 154 patients underwent the Ross (n = 105) and Ross-Konno (n = 49) procedure at our institution and were included in this study. Data were collected retrospectively from patients' medical records or through telephone contact. Competing risks analyses were performed to determine incidence...
Abstract
Cited 19 times since 2017 (2.4 per year)
source: EuropePMC
RNA biology,
Volume 14, Issue 9, 23 4 2017, Pages 1089-1098
Antibodies specific for nucleic acid modifications.
Feederle R, Schepers A
Nucleotide modifications constitute marks in RNA and DNA that contribute to gene regulation, development and other cellular processes. The understanding of their intricate molecular roles has been hampered by the high number of different modifications, the lack of effective methods and tools for their detection and quantification as well as by their complex structure-function relationship. The recent development of RNA and DNA immunoprecipitation followed by high-throughput sequencing (RIP- and...
Abstract
Cited 9 times since 2017 (1.1 per year)
source: EuropePMC
Annals of intensive care,
Volume 7, Issue 1, 23 4 2017, Pages 20
Hemodynamic effects of short-term hyperoxia after coronary artery bypass grafting.
Helmerhorst HJF, de Wilde RBP, Lee DH, Palmen M, Jansen JRC, van Westerloo DJ, de Jonge E
Background: Although oxygen is generally administered in a liberal manner in the perioperative setting, the effects of oxygen administration on dynamic cardiovascular parameters, filling status and cerebral perfusion have not been fully unraveled. Our aim was to study the acute hemodynamic and microcirculatory changes before, during and after arterial hyperoxia in mechanically ventilated patients after coronary artery bypass grafting (CABG) surgery. Methods: This was a single-center physiologica...
Abstract
Cited 34 times since 2017 (4.2 per year)
source: EuropePMC
Circulation. Cardiovascular quality and outcomes,
Volume 10, Issue 2, 22 4 2017, Pages e003178
Does the Use of a Decision Aid Improve Decision Making in Prosthetic Heart Valve Selection? A Multicenter Randomized Trial.
Korteland NM, Ahmed Y, Koolbergen DR, Brouwer M, de Heer F, Kluin J, Bruggemans EF, Klautz RJ, Stiggelbout AM, Bucx JJ, Roos-Hesselink JW, Polak P, Markou T, van den Broek I, Ligthart R, Bogers AJ, Takkenberg JJ
Background: A Dutch online patient decision aid to support prosthetic heart valve selection was recently developed. A multicenter randomized controlled trial was conducted to assess whether use of the patient decision aid results in optimization of shared decision making in prosthetic heart valve selection. Methods and results: In a 5-center randomized controlled trial, patients were allocated to receive either standard preoperative care (control group) or additional access to the patient decisi...
Abstract
Cardiovascular revascularization medicine : including molecular interventions,
Volume 18, Issue 6 Suppl 1, 20 3 2017, Pages 48-51
Microcatheters: A valuable tool in the presence of a challenging coronary anatomy in the setting of acute coronary interventions. Case report and mini review.
Karalis I, Andreou C, Montero Cabezas JM, Schalij MJ
Popularity of microcatheters (MCs) is growing among interventional cardiologists, especially when complex coronary anatomy is involved. However, MCs are still considered by many as a niche tool and their value in common clinical practice and in the setting of acute coronary interventions has not been fully appreciated. This case report highlights the decisive role of MC use in the successful completion of a primary percutaneous coronary intervention. Characteristics and indications of the most c...
Abstract
Cited 11 times since 2017 (1.4 per year)
source: EuropePMC
Archives of cardiovascular diseases,
Volume 110, Issue 5, 17 3 2017, Pages 354-362
Ventricular arrhythmias and sudden death in tetralogy of Fallot.
Maury P, Sacher F, Rollin A, Mondoly P, Duparc A, Zeppenfeld K, Hascoet S, Réseau francophone de rythmologie pédiatrique et congénitale
Malignant ventricular arrhythmias and sudden cardiac death may late happen in repaired tetralogy of Fallot, although probably less frequently than previously thought, especially with the advent of new surgical techniques/management. Ventricular tachycardias are caused by reentry around the surgical scars/patches and valves. Many predictive factors have been proposed, which suffer from poor accuracy. There is currently no recommended indication for prophylactic implantable cardioverter defibrilla...
Abstract
Cited 9 times since 2017 (1.1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 119, Issue 9, 9 2 2017, Pages 1456-1462
Relation of Myocardial Contrast-Enhanced T<sub>1</sub> Mapping by Cardiac Magnetic Resonance to Left Ventricular Reverse Remodeling After Cardiac Resynchronization Therapy in Patients With Nonischemic Cardiomyopathy.
Höke U, Khidir MJ, van der Geest RJ, Schalij MJ, Bax JJ, Delgado V, Ajmone Marsan N
Myocardial scar is known to be associated with limited left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). However, the impact of diffuse myocardial interstitial fibrosis, as assessed with myocardial T1 mapping cardiac magnetic resonance (CMR), has not been studied in patients with CRT. Therefore, we aimed at evaluating the association between diffuse myocardial interstitial fibrosis, in nonischemic cardiomyopathy patients, and LV reverse remodeling after CRT....
Abstract
Cited 11 times since 2017 (1.4 per year)
source: EuropePMC
European journal of heart failure,
Volume 19, Issue 9, 8 2 2017, Pages 1145-1151
Impact of QRS complex duration and morphology on left ventricular reverse remodelling and left ventricular function improvement after cardiac resynchronization therapy.
van der Bijl P, Khidir M, Leung M, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
Aims: To evaluate the impact of the interaction of QRS duration and morphology on left ventricular (LV) reverse remodelling and LV functional improvement in heart failure (HF) patients treated with cardiac resynchronization therapy (CRT). Methods and results: From an ongoing registry of HF patients treated with CRT according to contemporary guidelines, demographic, clinical, electrocardiographic (ECG) and echocardiographic characteristics were analysed. Patients were divided according to QRS dur...
Abstract
