Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9132 results
Cited 16 times since 2013 (1.3 per year) source: EuropePMC
Journal of clinical psychopharmacology, Volume 33, Issue 4, 1 1 2013, Pages 546-550 Association between genetic variation in the ABCB1 gene and switching, discontinuation, and dosage of antidepressant therapy: results from the Rotterdam Study. Noordam R, Aarts N, Hofman A, van Schaik RH, Stricker BH, Visser LE
The objective of this study was to investigate whether polymorphisms in the ABCB1 gene were associated with switching, with discontinuation of antidepressants within 45 days after starting therapy, and/or with dose change in a large prospective population-based cohort study. Between April 1, 1991, and December 31, 2007, there were 1257 incident users of antidepressants with known ABCB1 genotypes (1236C>T, 2677G>T/A, 3435C>T) in the population-based Rotterdam Study. Logistic regression m... Abstract
Cited 7 times since 2013 (0.6 per year) source: EuropePMC
Spine, Volume 38, Issue 18, 1 1 2013, Pages 1590-1594 An evaluation of web sites recommended by UK NHS consultants to patients with adolescent idiopathic scoliosis at the first point of diagnosis. Wellburn S, Bettany-Saltikov J, van Schaik P
Study design: An Internet-based evaluation of Web sites using a validated assessment tool. Objective: To evaluate the quality of information on scoliosis Web sites recommended by UK NHS consultants. Summary of background data: One of the most common sources of inquiry on the Web is for the purposes of health-related information. The number of Web sites in the field of scoliosis has increased, yet the quality of information is reported to continue to be of poor quality. The 2 previous studies in... Abstract
Cited 8 times since 2013 (0.7 per year) source: EuropePMC
Kidney international, Volume 85, Issue 1, 31 5 2013, Pages 94-102 Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling. San-Cristobal P, Lainez S, Dimke H, de Graaf MJ, Hoenderop JG, Bindels RJ
The voltage-gated potassium channel, Kv1.1, was recently identified as a causative gene in isolated dominant hypomagnesemia. The channel is situated in the distal convoluted tubule, where it participates in maintaining a favorable electrical gradient for driving magnesium ion into the cell through the transient receptor potential melastatin 6 channel. Pull-down experiments coupled to mass spectrometry using the carboxy-terminal domain of Kv1.1 as bait were used in mouse kidney lysates. Ankyrin-3... Abstract
Cited 81 times since 2013 (6.8 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 62, Issue 21, 31 5 2013, Pages 1966-1976 Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EPA, Li M, Leusink M, Trompet S, Verschuren JJW, Hovingh GK, Dehghan A, Nelson CP, Kotti S, Danchin N, Scholz M, Haase CL, Rothenbacher D, Swerdlow DI, Kuchenbaecker KB, Staines-Urias E, Goel A, van 't Hooft F, Gertow K, de Faire U, Panayiotou AG, Tremoli E, Baldassarre D, Veglia F, Holdt LM, Beutner F, Gansevoort RT, Navis GJ, Mateo Leach I, Breitling LP, Brenner H, Thiery J, Dallmeier D, Franco-Cereceda A, Boer JMA, Stephens JW, Hofker MH, Tedgui A, Hofman A, Uitterlinden AG, Adamkova V, Pitha J, Onland-Moret NC, Cramer MJ, Nathoe HM, Spiering W, Klungel OH, Kumari M, Whincup PH, Morrow DA, Braund PS, Hall AS, Olsson AG, Doevendans PA, Trip MD, Tobin MD, Hamsten A, Watkins H, Koenig W, Nicolaides AN, Teupser D, Day INM, Carlquist JF, Gaunt TR, Ford I, Sattar N, Tsimikas S, Schwartz GG, Lawlor DA, Morris RW, Sandhu MS, Poledne R, Maitland-van der
Objectives: This study sought to investigate the role of secretory phospholipase A2 (sPLA2)-IIA in cardiovascular disease. Background: Higher circulating levels of sPLA2-IIA mass or sPLA2 enzyme activity have been associated with increased risk of cardiovascular events. However, it is not clear if this association is causal. A recent phase III clinical trial of an sPLA2 inhibitor (varespladib) was stopped prematurely for lack of efficacy. Methods: We conducted a Mendelian randomization meta-anal... Abstract
Cited 13 times since 2013 (1.1 per year) source: EuropePMC
Resuscitation, Volume 84, Issue 11, 30 5 2013, Pages 1530-1535 Association between angiographic culprit lesion and out-of-hospital cardiac arrest in ST-elevation myocardial infarction patients. Velders MA, van Boven N, Boden H, van der Hoeven BL, Heestermans AA, Jukema JW, de Jonge E, Kuiper MA, van Boven AJ, Hofma SH, Schalij MJ, Umans VA
Background: Factors related to the occurrence of out-of-hospital cardiac arrest (OHCA) in ST-elevation myocardial infarction (STEMI) are still poorly understood. The current study sought to compare STEMI patients presenting with and without OHCA to identify angiographic factors related to OHCA. Methods: This multicenter registry consisted of consecutive STEMI patients, including OHCA patients with return-of-spontaneous circulation. Patients were treated with primary percutaneous coronary interve... Abstract
Cited 443 times since 2013 (37.2 per year) source: EuropePMC
PloS one, Volume 8, Issue 7, 30 5 2013, Pages e65174 The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, Wormser D, Kaptoge S, Whitlock G, Qiao Q, Lewington S, Di Angelantonio E, Vander Hoorn S, Lawes CM, Ali MK, Mozaffarian D, Ezzati M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group; Asia-Pacific Cohort Studies Collaboration (APCSC), Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in Europe (DECODE), Emerging Risk Factor Collaboration (ERFC), Prospective Studies Collaboration (PSC)
Background: The effects of systolic blood pressure (SBP), serum total cholesterol (TC), fasting plasma glucose (FPG), and body mass index (BMI) on the risk of cardiovascular diseases (CVD) have been established in epidemiological studies, but consistent estimates of effect sizes by age and sex are not available. Methods: We reviewed large cohort pooling projects, evaluating effects of baseline or usual exposure to metabolic risks on ischemic heart disease (IHD), hypertensive heart disease (HHD),... Abstract
Cited 35 times since 2013 (2.9 per year) source: EuropePMC
Preventive veterinary medicine, Volume 112, Issue 1-2, 30 5 2013, Pages 35-47 Schmallenberg virus epidemic in the Netherlands: spatiotemporal introduction in 2011 and seroprevalence in ruminants. Veldhuis AM, van Schaik G, Vellema P, Elbers AR, Bouwstra R, van der Heijden HM, Mars MH
This study aimed at estimating the Schmallenberg virus (SBV) seroprevalence in dairy heifers, non-dairy adult cattle, sheep and goats in the Netherlands after cessation of SBV transmission at the end of 2011. Archived serum samples from ruminants submitted to the GD Animal Health Service for monitoring purposes between November 2011 and March 2012 were selected and tested for presence of SBV-specific antibodies using an in-house ELISA. Animal seroprevalences were estimated at 63.4% in dairy heif... Abstract
Cited 4 times since 2013 (0.3 per year) source: EuropePMC
PloS one, Volume 8, Issue 7, 29 5 2013, Pages e69796 Connectivity between migrating and landlocked populations of a diadromous fish species investigated using otolith microchemistry. Tulp I, Keller M, Navez J, Winter HV, de Graaf M, Baeyens W
Smelt Osmerus eperlanus has two different life history strategies in The Netherlands. The migrating population inhabits the Wadden Sea and spawns in freshwater areas. After the closure of the Afsluitdijk in 1932, part of the smelt population became landlocked. The fresh water smelt population has been in severe decline since 1990, and has strongly negatively impacted the numbers of piscivorous water birds relying on smelt as their main prey. The lakes that were formed after the dike closure, IJs... Abstract
Cited 1 times since 2013 (0.1 per year) source: EuropePMC
BMJ case reports, Volume 2013, 29 5 2013, Pages bcr2013010219 An unusual cause of constipation in a 72-year-old man with a rising creatinine. Pimenta D, Yilmaz D, Grossman R, Soin B
Cited 112 times since 2013 (9.4 per year) source: EuropePMC
BMJ (Clinical research ed.), Volume 347, 29 5 2013, Pages f4600 Association of visit-to-visit variability in blood pressure with cognitive function in old age: prospective cohort study. Sabayan B, Wijsman LW, Foster-Dingley JC, Stott DJ, Ford I, Buckley BM, Sattar N, Jukema JW, van Osch MJ, van der Grond J, van Buchem MA, Westendorp RG, de Craen AJ, Mooijaart SP
Objective: To investigate the association between visit-to-visit variability in blood pressure and cognitive function in old age (>70 years). Design: Prospective cohort study. Setting: PROSPER (PROspective Study of Pravastatin in the Elderly at Risk) study, a collaboration between centres in Ireland, Scotland, and the Netherlands. Participants: 5461 participants, mean age 75.3 years, who were at risk of cardiovascular disease. Blood pressure was measured every three months during an average o... Abstract
Cited 6 times since 2013 (0.5 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 29, Issue 8, 27 4 2013, Pages 1829-1837 Association of atherosclerosis in the descending thoracic aorta with coronary artery disease on multi detector row computed tomography coronary angiography in patients with suspected coronary artery disease. Roos CJ, Witkowska AJ, de Graaf MA, Veltman CE, Delgado V, de Grooth GJ, Jukema JW, Bax JJ, Scholte AJ
The association between atherosclerosis in the descending thoracic aorta (DTA) visualized on computed tomography coronary angiography (CTA) and coronary artery disease (CAD) has not been extensively explored. Therefore, a comprehensive analysis of DTA atherosclerosis on CTA was performed and the association of DTA atherosclerosis with CAD was evaluated in patients with suspected CAD. A total of 344 patients (54 ± 12 years, 54% men) with suspected CAD underwent CTA. CTA were classified based on C... Abstract
Cited 5 times since 2013 (0.4 per year) source: EuropePMC
Renal failure, Volume 35, Issue 8, 26 4 2013, Pages 1163-1166 Intravascular large B-cell lymphoma presenting with anasarca-type edema and acute renal failure. Bilgili SG, Yılmaz D, Soyoral YU, Karadag AS, Bayram I
Intravascular lymphoma (IVL) is a rare extra nodal subtype (usually of B-cell origin) presenting with infiltration of large neoplastic lymphocytes into lumina of blood vessels, leading to vascular occlusion. The early diagnosis is very crucial, however it is usually diagnosed postmortem investigation in most of the cases. A 56-year-old female presented with elevated creatinine level, and anasarca-type edema that superimposed with hard, indurated, erythematous plaques extending to inguinal region... Abstract
Cited 19 times since 2013 (1.6 per year) source: EuropePMC
BMC palliative care, Volume 12, Issue 1, 23 4 2013, Pages 26 Improving palliative care outcomes for Aboriginal Australians: service providers' perspectives. Shahid S, Bessarab D, van Schaik KD, Aoun SM, Thompson SC
Background: Aboriginal Australians have a lower rate of utilisation of palliative care services than the general population. This study aimed to explore care providers' experiences and concerns in providing palliative care for Aboriginal people, and to identify opportunities for overcoming gaps in understanding between them and their Aboriginal patients and families. Methods: In-depth, qualitative interviews with urban, rural and remote palliative care providers were undertaken in inpatient... Abstract
Cited 734 times since 2013 (61.6 per year) source: EuropePMC
Nature reviews. Clinical oncology, Volume 10, Issue 9, 23 4 2013, Pages 507-518 Image-guided cancer surgery using near-infrared fluorescence. Vahrmeijer AL, Hutteman M, van der Vorst JR, van de Velde CJ, Frangioni JV
Paradigm shifts in surgery arise when surgeons are empowered to perform surgery faster, better and less expensively than current standards. Optical imaging that exploits invisible near-infrared (NIR) fluorescent light (700-900 nm) has the potential to improve cancer surgery outcomes, minimize the time patients are under anaesthesia and lower health-care costs largely by way of its improved contrast and depth of tissue penetration relative to visible light. Accordingly, the past few years have wi... Abstract
Cited 103 times since 2013 (8.6 per year) source: EuropePMC
The Journal of physiology, Volume 591, Issue 17, 22 4 2013, Pages 4189-4206 Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs. Jost N, Virág L, Comtois P, Ordög B, Szuts V, Seprényi G, Bitay M, Kohajda Z, Koncz I, Nagy N, Szél T, Magyar J, Kovács M, Puskás LG, Lengyel C, Wettwer E, Ravens U, Nánási PP, Papp JG, Varró A, Nattel S
The species-specific determinants of repolarization are poorly understood. This study compared the contribution of various currents to cardiac repolarization in canine and human ventricle. Conventional microelectrode, whole-cell patch-clamp, molecular biological and mathematical modelling techniques were used. Selective IKr block (50-100 nmol l(-1) dofetilide) lengthened AP duration at 90% of repolarization (APD90) >3-fold more in human than dog, suggesting smaller repolarization reserve in h... Abstract
Cited 30 times since 2013 (2.5 per year) source: EuropePMC
Diabetes care, Volume 36, Issue 11, 22 4 2013, Pages 3498-3502 Risk of a recurrent cardiovascular event in individuals with type 2 diabetes or intermediate hyperglycemia: the Hoorn Study. van der Heijden AA, Van't Riet E, Bot SD, Cannegieter SC, Stehouwer CD, Baan CA, Dekker JM, Nijpels G
Objective: To investigate risk of a recurrent cardiovascular event and its predictors in a population-based cohort. Research design and methods: Participants of the Hoorn Study who had experienced a first cardiovascular event after baseline (n = 336) were followed with respect to a recurrent event. Absolute risk of a recurrent event was calculated for individuals with normal glucose metabolism, intermediate hyperglycemia, and type 2 diabetes. Cox regression models were used to investigate which... Abstract
Cited 29 times since 2013 (2.4 per year) source: EuropePMC
Seminars in fetal & neonatal medicine, Volume 18, Issue 5, 22 4 2013, Pages 237-244 Embryology of the heart and its impact on understanding fetal and neonatal heart disease. Gittenberger-de Groot AC, Bartelings MM, Poelmann RE, Haak MC, Jongbloed MR
Heart development is a complex process during which the heart needs to transform from a single tube towards a fully septated heart with four chambers and a separated outflow tract. Several major events contribute to this process, that largely overlap in time. Abnormal heart development results in congenital heart disease, which has an estimated incidence of 1% of liveborn children. Eighty percent of cases of congenital heart disease are considered to have a multifactoral developmental background... Abstract
Cited 8 times since 2013 (0.7 per year) source: EuropePMC
Journal of vascular surgery, Volume 58, Issue 6, 21 3 2013, Pages 1452-1457.e1 Validation of three models predicting in-hospital death in patients with an abdominal aortic aneurysm eligible for both endovascular and open repair. van Beek SC, Blankensteijn JD, Balm R, Dutch Randomised Endovascular Aneurysm Management (DREAM) trial collaborators
Objective: The Medicare, the Vascular Governance North West (VGNW), and the British Aneurysm Repair (BAR) models can be used to predict in-hospital death after an intervention for an asymptomatic abdominal aortic aneurysm (AAA). Validation of these models in patients with suitable aortic anatomy for endovascular repair and a general condition fit for open repair is lacking. We validated the Medicare, VGNW, and BAR models in patients from a randomized controlled trial comparing open and endovascu... Abstract
Cited 36 times since 2013 (3 per year) source: EuropePMC
The American journal of cardiology, Volume 112, Issue 8, 19 3 2013, Pages 1197-1206 Arrhythmogenic right ventricular dysplasia/cardiomyopathy according to revised 2010 task force criteria with inclusion of non-desmosomal phospholamban mutation carriers. Groeneweg JA, van der Zwaag PA, Olde Nordkamp LR, Bikker H, Jongbloed JD, Jongbloed R, Wiesfeld AC, Cox MG, van der Heijden JF, Atsma DE, de Boer K, Doevendans PA, Vink A, van Veen TA, Dooijes D, van den Berg MP, Wilde AA, van Tintelen JP, Hauer RN
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is frequently associated with desmosomal mutations. However, nondesmosomal mutations may be involved. The aim of this study was to assess the contribution of a phospholamban (PLN) gene mutation to ARVD/C diagnosis according to the revised 2010 task force criteria (TFC). In 142 Dutch patients (106 men, mean age 51 ± 13 years) with proven ARVD/C (fulfillment of 2010 TFC for diagnosis), 5 known desmosomal genes (PKP2, DSP, DSC2, DSG... Abstract
Cited 10 times since 2013 (0.8 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 15, Issue 2, 18 3 2013, Pages 189-194 Ventricular response to dobutamine stress relates to the change in peak oxygen uptake during the 5-year follow-up in young patients with repaired tetralogy of Fallot. Luijnenburg SE, Mekic S, van den Berg J, van der Geest RJ, Moelker A, Roos-Hesselink JW, Bogers AJ, de Rijke YB, Strengers JL, Mulder BJ, Vliegen HW, Helbing WA
Aims: To evaluate the additional value of dobutamine stress testing in patients with repaired tetralogy of Fallot (TOF) by relating stress imaging parameters at baseline to relevant parameters of clinical condition and right ventricular (RV) size during a serial follow-up. Methods and results: We prospectively included 27 patients (14 ± 4 years at baseline), who were studied twice with a 5-year interval. Patients underwent cardiovascular magnetic resonance imaging to assess RV systolic and diast... Abstract