6177 results
Circulation. Cardiovascular imaging,
Volume 14, Issue 4, 2 1 2021, Pages e011688
Multimodality Evaluation of a Septal Cystic Cavity and Ventricular Septal Defect in the Setting of Neurocysticercosis and Endocarditis.
Schuuring MJ, van der Bom T, Konings TC, Götte MJW, Koolbergen DR, Boekholdt SM, de Winter RJ
Abstract
Cited 36 times since 2021 (8.9 per year)
source: EuropePMC
Human molecular genetics,
Volume 30, Issue 5, 1 1 2021, Pages 393-409
Genome-wide association study of circulating interleukin 6 levels identifies novel loci.
Ahluwalia TS, Prins BP, Abdollahi M, Armstrong NJ, Aslibekyan S, Bain L, Jefferis B, Baumert J, Beekman M, Ben-Shlomo Y, Bis JC, Mitchell BD, de Geus E, Delgado GE, Marek D, Eriksson J, Kajantie E, Kanoni S, Kemp JP, Lu C, Marioni RE, McLachlan S, Milaneschi Y, Nolte IM, Petrelis AM, Porcu E, Sabater-Lleal M, Naderi E, Seppälä I, Shah T, Singhal G, Standl M, Teumer A, Thalamuthu A, Thiering E, Trompet S, Ballantyne CM, Benjamin EJ, Casas JP, Toben C, Dedoussis G, Deelen J, Durda P, Engmann J, Feitosa MF, Grallert H, Hammarstedt A, Harris SE, Homuth G, Hottenga JJ, Jalkanen S, Jamshidi Y, Jawahar MC, Jess T, Kivimaki M, Kleber ME, Lahti J, Liu Y, Marques-Vidal P, Mellström D, Mooijaart SP, Müller-Nurasyid M, Penninx B, Revez JA, Rossing P, Räikkönen K, Sattar N, Scharnagl H, Sennblad B, Silveira A, Pourcain BS, Timpson NJ, Trollor J, CHARGE Inflammation Working Group, van Dongen J, Van Heemst D, Visvikis-Siest S, Vollenweider P, Völker U, Waldenberger M, Willemsen G, Zabaneh D, Morris RW, Arnett DK, Baune BT,
Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease pathogenesis. We conducted a two-staged, discovery and replication meta genome-wide association study (GWAS) of circulating serum IL-6 levels comprising up to 67 428 (ndiscovery = 52 654 and nreplication = 14 774) individuals of European ancestry. The inv...
Abstract
Cited 14 times since 2021 (3.4 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 32, Issue 4, 1 1 2021, Pages 506-514
Evolution from mitral annular dysfunction to severe mitral regurgitation in Barlow's disease.
Hiemstra YL, Tomsic A, Gripari P, van Wijngaarden AL, van der Pas SL, Palmen M, Klautz RJM, Pepi M, Bax JJ, Delgado V, Marsan NA
Objectives: Barlow's disease (BD) is characterized by thick, redundant mitral valve (MV) leaflets, which can lead to prolapse and significant mitral regurgitation (MR). MV annular abnormalities are also commonly observed and increasingly recognized as possible primary pathology, with leaflet thickening being secondary to increased stress on the MV apparatus. To provide more insights into this hypothesis, the evolution of MV abnormalities over time in patients with BD was assessed. Methods:...
Abstract
European heart journal. Cardiovascular Imaging,
Volume 22, Issue 5, 1 1 2021, Pages 516-517
Prognostic significance of left ventricular diastolic dysfunction and filling pressures based on current guideline recommendations.
Ng ACT, Narula J, Bax JJ
Abstract
Cited 1 times since 2021 (0.2 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 4, 1 1 2021, Pages 880-881
The Authors Reply.
Namazi F, Delgado V, Bax JJ
Abstract
Cited 19 times since 2021 (4.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 22, Issue 5, 1 1 2021, Pages 471-479
The structural heart disease interventional imager rationale, skills and training: a position paper of the European Association of Cardiovascular Imaging.
Agricola E, Ancona F, Brochet E, Donal E, Dweck M, Faletra F, Lancellotti P, Mahmoud-Elsayed H, Marsan NA, Maurovich-Hovart P, Monaghan M, Ribeiro J, Sade LE, Swaans M, Von Bardeleben RS, Wunderlich N, Zamorano JL, Popescu BA, Cosyns B, Edvardsen T, Reviewers: This document was reviewed by members of the 2018-2020 EACVI Scientific Documents Committee
Percutaneous therapeutic options for an increasing variety of structural heart diseases (SHD) have grown dramatically. Within this context of continuous expansion of devices and procedures, there has been increased demand for physicians with specific knowledge, skills, and advanced training in multimodality cardiac imaging. As a consequence, a new subspecialty of 'Interventional Imaging' for SHD interventions and a new dedicated professional figure, the 'Interventional Imager'...
Abstract
Cited 7 times since 2021 (1.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 22, Issue 5, 1 1 2021, Pages 589-596
Assessment of left atrial electro-mechanical delay to predict atrial fibrillation in hypertrophic cardiomyopathy.
Tjahjadi C, Hiemstra YL, van der Bijl P, Pio SM, Bootsma M, Ajmone Marsan N, Delgado V, Bax JJ
Aims: Atrial fibrillation (AF) is frequently observed in hypertrophic cardiomyopathy (HCM) and is associated with poor clinical outcome. Total atrial conduction time, estimated by tissue Doppler imaging (TDI), the so-called PA-TDI duration, reflects the left atrial (LA) structural and electrical remodelling. The aim of this study was to evaluate the association between PA-TDI and new-onset AF in patients with HCM. Methods and results: From a large cohort of patients with HCM, 208 patients (64% m...
Abstract
Cited 4 times since 2021 (1 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 59, Issue 4, 1 1 2021, Pages 814-822
Wall shear stress in the thoracic aorta at rest and with dobutamine stress after arterial switch operation.
van der Palen RLF, Juffermans JF, Kroft LJM, Hazekamp MG, Lamb HJ, Blom NA, Roest AAW, Westenberg JJM
Objectives: Progressive root dilatation is an important complication in patients with transposition of the great arteries (TGA) after arterial switch operation (ASO) that may be caused by altered flow dynamics. Aortic wall shear stress (WSS) distribution at rest and under dobutamine stress (DS) conditions using 4D flow magnetic resonance imaging were investigated in relation to thoracic aorta geometry. Methods: 4D flow magnetic resonance imaging was performed in 16 adolescent TGA patients after...
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 59, Issue 4, 1 1 2021, Pages 830-831
We can, but should we?
Hazekamp MG, Sojak V
Abstract
Cited 12 times since 2021 (3 per year)
source: EuropePMC
Journal of patient safety,
Volume 17, Issue 3, 1 1 2021, Pages 157-165
Preoperative Anticoagulation Management in Everyday Clinical Practice: An International Comparative Analysis of Work-as-Done Using the Functional Resonance Analysis Method.
Damen NL, de Vos MS, Moesker MJ, Braithwaite J, de Lind van Wijngaarden RAF, Kaplan J, Hamming JF, Clay-Williams R
Objectives: Preoperative anticoagulation management (PAM) is a complex, multidisciplinary process important to patient safety. The Functional Resonance Analysis Method (FRAM) is a novel method to study how complex processes usually go right at the frontline (labeled Safety-II) and how this relates to predefined procedures. This study aimed to assess PAM in everyday practice and explore the usability and utility of FRAM. Methods: The study was conducted at an Australian and European Cardiothoraci...
Abstract
Cited 7 times since 2021 (1.7 per year)
source: EuropePMC
Journal of patient safety,
Volume 17, Issue 3, 1 1 2021, Pages 231-238
Learning From Morbidity and Mortality Conferences: Focus and Sustainability of Lessons for Patient Care.
de Vos MS, Hamming JF, Marang-van de Mheen PJ
Objective: It remains unclear to what extent the morbidity and mortality conference (M&M) meets the objective of improving quality and safety of patient care. It has been suggested that M&M may be too focused on individual performance, hampering system-level improvement. The aim of this study was to assess focus and sustainability of lessons for patient care that were derived from M&M. Methods: This is an observational study of routinely collected data on evaluated complications and...
Abstract
Cited 16 times since 2021 (3.9 per year)
source: EuropePMC
Cells,
Volume 10, Issue 4, 26 4 2021, Pages 737
The Inflammatory Profile of CTEPH-Derived Endothelial Cells Is a Possible Driver of Disease Progression.
Smolders VFED, Lodder K, Rodríguez C, Tura-Ceide O, Barberà JA, Jukema JW, Quax PHA, Goumans MJ, Kurakula K
Chronic thromboembolic pulmonary hypertension (CTEPH) is a form of pulmonary hypertension characterized by the presence of fibrotic intraluminal thrombi and causing obliteration of the pulmonary arteries. Although both endothelial cell (EC) dysfunction and inflammation are linked to CTEPH pathogenesis, regulation of the basal inflammatory response of ECs in CTEPH is not fully understood. Therefore, in the present study, we investigated the role of the nuclear factor (NF)-κB pro-inflammatory sign...
Abstract
Cited 54 times since 2021 (13.2 per year)
source: EuropePMC
Biomedicines,
Volume 9, Issue 4, 24 4 2021, Pages 328
Endothelial Barrier Function and Leukocyte Transmigration in Atherosclerosis.
Sluiter TJ, van Buul JD, Huveneers S, Quax PHA, de Vries MR
The vascular endothelium is a highly specialized barrier that controls passage of fluids and migration of cells from the lumen into the vessel wall. Endothelial cells assist leukocytes to extravasate and despite the variety in the specific mechanisms utilized by different leukocytes to cross different vascular beds, there is a general principle of capture, rolling, slow rolling, arrest, crawling, and ultimately diapedesis via a paracellular or transcellular route. In atherosclerosis, the barrier...
Abstract
Cited 27 times since 2021 (6.6 per year)
source: EuropePMC
Thorax,
Volume 76, Issue 10, 23 4 2021, Pages 1002-1009
Non-invasive early exclusion of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: the InShape II study.
Boon GJAM, Ende-Verhaar YM, Bavalia R, El Bouazzaoui LH, Delcroix M, Dzikowska-Diduch O, Huisman MV, Kurnicka K, Mairuhu ATA, Middeldorp S, Pruszczyk P, Ruigrok D, Verhamme P, Vliegen HW, Vonk Noordegraaf A, Vriend JWJ, Klok FA, InShape II study group
Background: The current diagnostic delay of chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism (PE) is unacceptably long, causing loss of quality-adjusted life years and excess mortality. Validated screening strategies for early CTEPH diagnosis are lacking. Echocardiographic screening among all PE survivors is associated with overdiagnosis and cost-ineffectiveness. We aimed to validate a simple screening strategy for excluding CTEPH early after acute PE, limiting the...
Abstract
Cited 6 times since 2021 (1.5 per year)
source: EuropePMC
Scientific reports,
Volume 11, Issue 1, 22 4 2021, Pages 6507
Reduced scan time and superior image quality with 3D flow MRI compared to 4D flow MRI for hemodynamic evaluation of the Fontan pathway.
Rijnberg FM, van Assen HC, Juffermans JF, Kroft LJM, van den Boogaard PJ, de Koning PJH, Hazekamp MG, van der Woude SFS, Warmerdam EG, Leiner T, Grotenhuis HB, Goeman JJ, Lamb HJ, Roest AAW, Westenberg JJM
Long scan times prohibit a widespread clinical applicability of 4D flow MRI in Fontan patients. As pulsatility in the Fontan pathway is minimal during the cardiac cycle, acquiring non-ECG gated 3D flow MRI may result in a reduction of scan time while accurately obtaining time-averaged clinical parameters in comparison with 2D and 4D flow MRI. Thirty-two Fontan patients prospectively underwent 2D (reference), 3D and 4D flow MRI of the Fontan pathway. Multiple clinical parameters were assessed fro...
Abstract
Cited 3 times since 2021 (0.7 per year)
source: EuropePMC
Access microbiology,
Volume 3, Issue 3, 22 4 2021, Pages 000217
<i>Bartonella quintana</i> as a cause for prosthetic valve endocarditis and post-sternotomy mediastinitis.
Plantinga NL, Vos RJ, Georgieva L, Roescher N
An otherwise healthy patient, with minimal clinical, biochemical and peroperative signs of infection, was diagnosed with Bartonella quintana prosthetic valve endocarditis by 16S PCR. The patient subsequently developed a post-sternotomy mediastinitis and Bartonella quintana was the only detected pathogen. Bartonella quintana can cause severe infections in individuals not classically at risk, and may be missed in the routine diagnostic work-up of endocarditis.
Abstract
Cited 6 times since 2021 (1.5 per year)
source: EuropePMC
Heart rhythm O2,
Volume 2, Issue 3, 19 3 2021, Pages 290-297
Predicting early reconnection after cryoballoon ablation with procedural and biophysical parameters.
Keçe F, de Riva M, Alizadeh Dehnavi R, Wijnmaalen AP, Mertens BJ, Schalij MJ, Zeppenfeld K, Trines SA
Background: Predicting early reconnection/dormant conduction (ERC) immediately after pulmonary vein isolation (PVI) can avoid a waiting period with adenosine testing. Objective: To identify procedural and biophysical parameters predicting ERC. Methods: Consecutive atrial fibrillation (AF) patients undergoing a first cryoballoon ablation (Arctic Front Advance) between 2014 and 2017 were included. ERC was defined as manifest or dormant pulmonary vein (PV) reconnection with adenosine 30 minutes aft...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Diagnostics (Basel, Switzerland),
Volume 11, Issue 3, 19 3 2021, Pages 553
Radioiodine in Differentiated Thyroid Carcinoma: Do We Need Diagnostic Pre-Ablation Iodine-123 Scintigraphy to Optimize Treatment?
de Koster EJ, Sulaiman T, Hamming JF, Schepers A, Snel M, van Velden FHP, de Geus-Oei LF, Vriens D
Changing insights regarding radioiodine (I-131) administration in differentiated thyroid carcinoma (DTC) stir up discussions on the utility of pre-ablation diagnostic scintigraphy (DxWBS). Our retrospective study qualitatively and semi-quantitatively assessed posttherapy I-131 whole-body scintigraphy (TxWBS) data for thyroid remnant size and metastasis. Findings were associated with initial treatment success after nine months, as well as clinical, histopathological, and surgical parameters. Poss...
Abstract
Cited 11 times since 2021 (2.7 per year)
source: EuropePMC
BMC medicine,
Volume 19, Issue 1, 18 3 2021, Pages 69
Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses.
Bos MM, Goulding NJ, Lee MA, Hofman A, Bot M, Pool R, Vijfhuizen LS, Zhang X, Li C, Mustafa R, Neville MJ, Li-Gao R, Trompet S, Beekman M, Biermasz NR, Boomsma DI, de Boer I, Christodoulides C, Dehghan A, van Dijk KW, Ford I, Ghanbari M, Heijmans BT, Ikram MA, Jukema JW, Mook-Kanamori DO, Karpe F, Luik AI, Lumey LH, van den Maagdenberg AMJM, Mooijaart SP, de Mutsert R, Penninx BWJH, Rensen PCN, Richmond RC, Rosendaal FR, Sattar N, Schoevers RA, Slagboom PE, Terwindt GM, Thesing CS, Wade KH, Wijsman CA, Willemsen G, Zwinderman AH, van Heemst D, Noordam R, Lawlor DA
Background: Sleep traits are associated with cardiometabolic disease risk, with evidence from Mendelian randomization (MR) suggesting that insomnia symptoms and shorter sleep duration increase coronary artery disease risk. We combined adjusted multivariable regression (AMV) and MR analyses of phenotypes of unfavourable sleep on 113 metabolomic traits to investigate possible biochemical mechanisms linking sleep to cardiovascular disease. Methods: We used AMV (N = 17,368) combined with two-sample...
Abstract
Cited 6 times since 2021 (1.5 per year)
source: EuropePMC
Journal of molecular and cellular cardiology,
Volume 156, 18 3 2021, Pages 95-104
New calcification model for intact murine aortic valves.
Kruithof BPT, van de Pol V, Los T, Lodder K, Mousavi Gourabi B, DeRuiter MC, Goumans MJ, Ajmone Marsan N
Calcific aortic valve disease (CAVD) is a common progressive disease of the aortic valves, for which no medical treatment exists and surgery represents currently the only therapeutic solution. The development of novel pharmacological treatments for CAVD has been hampered by the lack of suitable test-systems, which require the preservation of the complex valve structure in a mechanically and biochemical controllable system. Therefore, we aimed at establishing a model which allows the study of cal...
Abstract
